Iwr1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q4K8_LEIMA

TriTrypDb:

LmjF.33.0150 , LMJLV39_330006800 , LMJSD75_330006700

Length:

279

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2

Previous1Next

Expansion

Sequence features

Q4Q4K8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4K8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.675
CLV_C14_Caspase3-7	68	72	PF00656	0.699
CLV_NRD_NRD_1	140	142	PF00675	0.640
CLV_NRD_NRD_1	203	205	PF00675	0.317
CLV_NRD_NRD_1	21	23	PF00675	0.630
CLV_NRD_NRD_1	247	249	PF00675	0.700
CLV_PCSK_KEX2_1	121	123	PF00082	0.686
CLV_PCSK_KEX2_1	139	141	PF00082	0.648
CLV_PCSK_KEX2_1	21	23	PF00082	0.630
CLV_PCSK_KEX2_1	247	249	PF00082	0.701

Previous1 2 3 4 5…11Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5U4	Leptomonas seymouri	44%	82%
A0A3S7X690	Leishmania donovani	88%	100%
A4HL52	Leishmania braziliensis	68%	100%
A4I8N1	Leishmania infantum	88%	100%
D0A4K8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	74%
E9B3J3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%

Previous1Next