Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Secreted protein

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q4K5_LEIMA

TriTrypDb:

LmjF.33.0180 , LMJLV39_330007200 , LMJSD75_330007100

Length:

162

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4K5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4K5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	33	37	PF00656	0.551
CLV_NRD_NRD_1	131	133	PF00675	0.553
CLV_PCSK_KEX2_1	131	133	PF00082	0.553
CLV_PCSK_SKI1_1	137	141	PF00082	0.701
DEG_APCC_DBOX_1	1	9	PF00400	0.648
DEG_Nend_UBRbox_1	1	4	PF02207	0.549
DOC_CYCLIN_RxL_1	131	143	PF00134	0.779
DOC_MAPK_gen_1	131	141	PF00069	0.554
DOC_MAPK_MEF2A_6	18	27	PF00069	0.476
DOC_MAPK_NFAT4_5	18	26	PF00069	0.488
DOC_PP1_RVXF_1	135	142	PF00149	0.553
DOC_PP4_FxxP_1	141	144	PF00568	0.547
DOC_USP7_MATH_1	120	124	PF00917	0.727
DOC_WW_Pin1_4	107	112	PF00397	0.721
LIG_14-3-3_CanoR_1	113	121	PF00244	0.593
LIG_14-3-3_CanoR_1	18	24	PF00244	0.416
LIG_14-3-3_CanoR_1	2	12	PF00244	0.527
LIG_14-3-3_CanoR_1	28	34	PF00244	0.490
LIG_14-3-3_CterR_2	160	162	PF00244	0.542
LIG_EH1_1	56	64	PF00400	0.520
LIG_FHA_1	100	106	PF00498	0.660
LIG_FHA_1	43	49	PF00498	0.527
LIG_FHA_2	31	37	PF00498	0.550
LIG_LIR_Gen_1	14	23	PF02991	0.488
LIG_LIR_Gen_1	87	97	PF02991	0.540
LIG_LIR_Nem_3	14	19	PF02991	0.578
LIG_LIR_Nem_3	87	93	PF02991	0.612
LIG_SH2_CRK	94	98	PF00017	0.549
LIG_SH2_STAP1	100	104	PF00017	0.561
LIG_SH2_STAT5	100	103	PF00017	0.633
LIG_SH2_STAT5	68	71	PF00017	0.541
LIG_SH3_3	69	75	PF00018	0.602
LIG_WRC_WIRS_1	100	105	PF05994	0.564
LIG_WRC_WIRS_1	121	126	PF05994	0.594
MOD_CDC14_SPxK_1	110	113	PF00782	0.565
MOD_CDK_SPxK_1	107	113	PF00069	0.723
MOD_CK1_1	123	129	PF00069	0.603
MOD_CK2_1	41	47	PF00069	0.490
MOD_GlcNHglycan	114	117	PF01048	0.486
MOD_GlcNHglycan	127	131	PF01048	0.511
MOD_GlcNHglycan	13	16	PF01048	0.464
MOD_GlcNHglycan	152	155	PF01048	0.722
MOD_GlcNHglycan	47	51	PF01048	0.522
MOD_GSK3_1	19	26	PF00069	0.480
MOD_GSK3_1	30	37	PF00069	0.457
MOD_GSK3_1	42	49	PF00069	0.510
MOD_GSK3_1	79	86	PF00069	0.733
MOD_NEK2_1	19	24	PF00069	0.411
MOD_NEK2_1	3	8	PF00069	0.529
MOD_NEK2_1	34	39	PF00069	0.500
MOD_NEK2_2	89	94	PF00069	0.558
MOD_PKA_2	112	118	PF00069	0.568
MOD_PKA_2	27	33	PF00069	0.455
MOD_PKA_2	3	9	PF00069	0.527
MOD_PKB_1	148	156	PF00069	0.619
MOD_PKB_1	2	10	PF00069	0.530
MOD_Plk_1	30	36	PF00069	0.489
MOD_Plk_1	79	85	PF00069	0.602
MOD_Plk_4	57	63	PF00069	0.512
MOD_Plk_4	89	95	PF00069	0.644
MOD_Plk_4	99	105	PF00069	0.503
MOD_ProDKin_1	107	113	PF00069	0.723
TRG_ENDOCYTIC_2	100	103	PF00928	0.469
TRG_ENDOCYTIC_2	68	71	PF00928	0.541
TRG_ENDOCYTIC_2	94	97	PF00928	0.547
TRG_ER_diArg_1	1	4	PF00400	0.646
TRG_ER_diArg_1	131	133	PF00400	0.567
TRG_ER_diArg_1	134	137	PF00400	0.574
TRG_ER_diArg_1	147	150	PF00400	0.538
TRG_Pf-PMV_PEXEL_1	32	36	PF00026	0.567

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X6D8	Leishmania donovani	84%	100%
A4I8N4	Leishmania infantum	82%	100%