LeishMANIAdb
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STI1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
STI1 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q4K1_LEIMA
TriTrypDb:
LmjF.33.0220 * , LMJLV39_330008000 * , LMJSD75_330007700 *
Length:
140

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0005739 mitochondrion 5 2
GO:0020023 kinetoplast 2 2
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043231 intracellular membrane-bounded organelle 4 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

Q4Q4K1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4K1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 62 66 PF00082 0.494
DEG_Nend_UBRbox_2 1 3 PF02207 0.493
DOC_PP2B_LxvP_1 89 92 PF13499 0.559
DOC_USP7_MATH_1 40 44 PF00917 0.613
DOC_WW_Pin1_4 15 20 PF00397 0.498
LIG_FHA_1 70 76 PF00498 0.468
LIG_FHA_2 93 99 PF00498 0.610
LIG_PDZ_Class_1 135 140 PF00595 0.495
MOD_CDK_SPxxK_3 15 22 PF00069 0.557
MOD_CK1_1 24 30 PF00069 0.494
MOD_CK2_1 124 130 PF00069 0.523
MOD_Cter_Amidation 56 59 PF01082 0.463
MOD_GlcNHglycan 126 129 PF01048 0.557
MOD_GlcNHglycan 30 33 PF01048 0.526
MOD_GSK3_1 24 31 PF00069 0.568
MOD_N-GLC_1 15 20 PF02516 0.564
MOD_NEK2_1 21 26 PF00069 0.600
MOD_NEK2_1 28 33 PF00069 0.633
MOD_NEK2_1 9 14 PF00069 0.560
MOD_PIKK_1 4 10 PF00454 0.571
MOD_PKA_2 21 27 PF00069 0.636
MOD_Plk_1 87 93 PF00069 0.609
MOD_Plk_4 24 30 PF00069 0.569
MOD_ProDKin_1 15 21 PF00069 0.498
TRG_ENDOCYTIC_2 67 70 PF00928 0.459

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I5B0 Leptomonas seymouri 75% 69%
A0A0S4KJX2 Bodo saltans 38% 73%
A0A3S7X6E1 Leishmania donovani 95% 100%
A4HL59 Leishmania braziliensis 86% 100%
E9B3K0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 69%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS