LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q4G3_LEIMA
TriTrypDb:
LmjF.33.0460 , LMJLV39_330010900 * , LMJSD75_330010900
Length:
288

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4G3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4G3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 190 194 PF00656 0.618
CLV_NRD_NRD_1 133 135 PF00675 0.537
CLV_NRD_NRD_1 138 140 PF00675 0.516
CLV_NRD_NRD_1 248 250 PF00675 0.623
CLV_NRD_NRD_1 53 55 PF00675 0.777
CLV_PCSK_KEX2_1 133 135 PF00082 0.546
CLV_PCSK_KEX2_1 138 140 PF00082 0.507
CLV_PCSK_KEX2_1 148 150 PF00082 0.421
CLV_PCSK_KEX2_1 225 227 PF00082 0.523
CLV_PCSK_KEX2_1 248 250 PF00082 0.623
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IHC5 Leishmania donovani 93% 100%
A4HL81 Leishmania braziliensis 67% 100%
A4I8Q9 Leishmania infantum 91% 100%
E9B3M4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS