Tubulin beta chain

Quick info Localization Phosphorylation Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Tubulin beta chain

Gene product:

beta tubulin

Species:

Leishmania major

UniProt:

Q4Q4C4_LEIMA

TriTrypDb:

LmjF.33.0812 , LMJLV39_330015200 , LMJSD75_080016300

Length:

443

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 1
Forrest at al. (metacyclic)	yes	yes: 3
Forrest at al. (procyclic)	yes	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 20

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 36

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 23
NetGPI	no	yes: 0, no: 23

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	4
GO:0005874	microtubule	6	24
GO:0099080	supramolecular complex	2	24
GO:0099081	supramolecular polymer	3	24
GO:0099512	supramolecular fiber	4	24
GO:0099513	polymeric cytoskeletal fiber	5	24
GO:0110165	cellular anatomical entity	1	24

Phosphorylation

Promastigote: 285

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

Q4Q4C4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4C4

Function

Biological processes
Term	Name	Level	Count
GO:0000226	microtubule cytoskeleton organization	3	4
GO:0000278	mitotic cell cycle	3	4
GO:0006996	organelle organization	4	4
GO:0007010	cytoskeleton organization	5	4
GO:0007017	microtubule-based process	2	24
GO:0007049	cell cycle	2	4
GO:0009987	cellular process	1	24
GO:0016043	cellular component organization	3	4
GO:0071840	cellular component organization or biogenesis	2	4

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	24
GO:0003824	catalytic activity	1	24
GO:0003924	GTPase activity	7	24
GO:0005198	structural molecule activity	1	24
GO:0005200	structural constituent of cytoskeleton	2	24
GO:0005488	binding	1	24
GO:0005525	GTP binding	5	24
GO:0016462	pyrophosphatase activity	5	24
GO:0016787	hydrolase activity	2	24
GO:0016817	hydrolase activity, acting on acid anhydrides	3	24
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	24
GO:0017076	purine nucleotide binding	4	24
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	24
GO:0019001	guanyl nucleotide binding	5	24
GO:0032553	ribonucleotide binding	3	24
GO:0032555	purine ribonucleotide binding	4	24
GO:0032561	guanyl ribonucleotide binding	5	24
GO:0035639	purine ribonucleoside triphosphate binding	4	24
GO:0036094	small molecule binding	2	24
GO:0043167	ion binding	2	24
GO:0043168	anion binding	3	24
GO:0097159	organic cyclic compound binding	2	24
GO:0097367	carbohydrate derivative binding	2	24
GO:1901265	nucleoside phosphate binding	3	24
GO:1901363	heterocyclic compound binding	2	24

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	111	115	PF00656	0.484
CLV_NRD_NRD_1	120	122	PF00675	0.330
CLV_NRD_NRD_1	250	252	PF00675	0.427
CLV_NRD_NRD_1	379	381	PF00675	0.309
CLV_NRD_NRD_1	390	392	PF00675	0.487
CLV_PCSK_KEX2_1	379	381	PF00082	0.309
CLV_PCSK_KEX2_1	390	392	PF00082	0.487
CLV_PCSK_SKI1_1	213	217	PF00082	0.423
CLV_PCSK_SKI1_1	309	313	PF00082	0.302
CLV_PCSK_SKI1_1	359	363	PF00082	0.302
CLV_PCSK_SKI1_1	391	395	PF00082	0.452
CLV_PCSK_SKI1_1	62	66	PF00082	0.284
DEG_APCC_DBOX_1	61	69	PF00400	0.484
DEG_Nend_UBRbox_1	1	4	PF02207	0.432
DOC_CKS1_1	217	222	PF01111	0.433
DOC_CYCLIN_RxL_1	210	221	PF00134	0.547
DOC_MAPK_gen_1	251	257	PF00069	0.416
DOC_MAPK_gen_1	359	367	PF00069	0.496
DOC_MAPK_MEF2A_6	359	367	PF00069	0.496
DOC_PP1_RVXF_1	260	266	PF00149	0.336
DOC_USP7_MATH_1	173	177	PF00917	0.484
DOC_USP7_MATH_1	231	235	PF00917	0.366
DOC_USP7_MATH_1	272	276	PF00917	0.484
DOC_USP7_MATH_1	32	36	PF00917	0.529
DOC_WW_Pin1_4	169	174	PF00397	0.484
DOC_WW_Pin1_4	216	221	PF00397	0.433
LIG_14-3-3_CanoR_1	162	168	PF00244	0.485
LIG_14-3-3_CanoR_1	174	182	PF00244	0.484
LIG_14-3-3_CanoR_1	282	287	PF00244	0.485
LIG_14-3-3_CanoR_1	309	317	PF00244	0.505
LIG_14-3-3_CanoR_1	318	326	PF00244	0.502
LIG_Actin_WH2_2	203	218	PF00022	0.484
LIG_Actin_WH2_2	346	364	PF00022	0.505
LIG_APCC_ABBA_1	47	52	PF00400	0.484
LIG_APCC_ABBAyCdc20_2	46	52	PF00400	0.484
LIG_BRCT_BRCA1_1	313	317	PF00533	0.502
LIG_BRCT_BRCA1_1	337	341	PF00533	0.502
LIG_BRCT_BRCA1_1	363	367	PF00533	0.574
LIG_CAP-Gly_1	435	443	PF01302	0.637
LIG_Clathr_ClatBox_1	65	69	PF01394	0.484
LIG_FHA_1	147	153	PF00498	0.482
LIG_FHA_1	164	170	PF00498	0.484
LIG_FHA_1	184	190	PF00498	0.484
LIG_FHA_1	212	218	PF00498	0.428
LIG_FHA_1	235	241	PF00498	0.372
LIG_FHA_1	321	327	PF00498	0.504
LIG_FHA_2	176	182	PF00498	0.486
LIG_FHA_2	219	225	PF00498	0.421
LIG_FHA_2	407	413	PF00498	0.462
LIG_FHA_2	427	433	PF00498	0.556
LIG_LIR_Gen_1	166	175	PF02991	0.484
LIG_LIR_Gen_1	18	25	PF02991	0.484
LIG_LIR_Nem_3	166	170	PF02991	0.484
LIG_LIR_Nem_3	18	24	PF02991	0.484
LIG_LIR_Nem_3	209	215	PF02991	0.533
LIG_LIR_Nem_3	219	225	PF02991	0.421
LIG_LIR_Nem_3	278	284	PF02991	0.485
LIG_LIR_Nem_3	376	381	PF02991	0.502
LIG_LIR_Nem_3	420	425	PF02991	0.471
LIG_MLH1_MIPbox_1	337	341	PF16413	0.502
LIG_PCNA_yPIPBox_3	371	380	PF02747	0.502
LIG_Pex14_2	266	270	PF04695	0.484
LIG_Pex14_2	385	389	PF04695	0.415
LIG_SH2_CRK	281	285	PF00017	0.484
LIG_SH2_CRK	81	85	PF00017	0.484
LIG_SH2_SRC	425	428	PF00017	0.488
LIG_SH2_STAP1	208	212	PF00017	0.484
LIG_SH2_STAT5	106	109	PF00017	0.484
LIG_SH2_STAT5	310	313	PF00017	0.502
LIG_SH2_STAT5	340	343	PF00017	0.502
LIG_SH2_STAT5	398	401	PF00017	0.441
LIG_SH2_STAT5	50	53	PF00017	0.488
LIG_SH2_STAT5	59	62	PF00017	0.497
LIG_SH3_3	176	182	PF00018	0.484
LIG_SH3_3	255	261	PF00018	0.411
LIG_SUMO_SIM_par_1	148	153	PF11976	0.482
LIG_SxIP_EBH_1	162	176	PF03271	0.484
LIG_TRAF2_1	429	432	PF00917	0.578
LIG_WRC_WIRS_1	164	169	PF05994	0.486
MOD_CDK_SPK_2	169	174	PF00069	0.484
MOD_CK1_1	196	202	PF00069	0.484
MOD_CK1_1	234	240	PF00069	0.371
MOD_CK1_1	275	281	PF00069	0.484
MOD_CK2_1	175	181	PF00069	0.484
MOD_CK2_1	282	288	PF00069	0.484
MOD_CK2_1	319	325	PF00069	0.502
MOD_CK2_1	406	412	PF00069	0.464
MOD_CK2_1	426	432	PF00069	0.537
MOD_GlcNHglycan	144	147	PF01048	0.289
MOD_GlcNHglycan	233	236	PF01048	0.385
MOD_GlcNHglycan	313	316	PF01048	0.302
MOD_GlcNHglycan	52	56	PF01048	0.313
MOD_GlcNHglycan	94	97	PF01048	0.287
MOD_GSK3_1	142	149	PF00069	0.484
MOD_GSK3_1	165	172	PF00069	0.484
MOD_GSK3_1	211	218	PF00069	0.420
MOD_GSK3_1	271	278	PF00069	0.485
MOD_GSK3_1	406	413	PF00069	0.475
MOD_LATS_1	307	313	PF00433	0.502
MOD_N-GLC_1	183	188	PF02516	0.284
MOD_N-GLC_1	336	341	PF02516	0.302
MOD_N-GLC_1	369	374	PF02516	0.304
MOD_N-GLC_2	371	373	PF02516	0.302
MOD_NEK2_1	112	117	PF00069	0.484
MOD_NEK2_1	133	138	PF00069	0.595
MOD_NEK2_1	150	155	PF00069	0.391
MOD_NEK2_1	165	170	PF00069	0.486
MOD_NEK2_1	215	220	PF00069	0.428
MOD_NEK2_1	311	316	PF00069	0.502
MOD_NEK2_1	361	366	PF00069	0.509
MOD_NEK2_1	51	56	PF00069	0.574
MOD_NEK2_1	92	97	PF00069	0.487
MOD_NEK2_2	211	216	PF00069	0.414
MOD_OFUCOSY	120	127	PF10250	0.284
MOD_PIKK_1	275	281	PF00454	0.484
MOD_PIKK_1	287	293	PF00454	0.484
MOD_PK_1	282	288	PF00069	0.484
MOD_PKA_2	173	179	PF00069	0.574
MOD_PKA_2	275	281	PF00069	0.484
MOD_PKA_2	319	325	PF00069	0.502
MOD_PKB_1	318	326	PF00069	0.502
MOD_Plk_1	183	189	PF00069	0.484
MOD_Plk_1	196	202	PF00069	0.484
MOD_Plk_1	336	342	PF00069	0.504
MOD_Plk_1	369	375	PF00069	0.502
MOD_Plk_1	426	432	PF00069	0.537
MOD_Plk_2-3	69	75	PF00069	0.484
MOD_Plk_4	112	118	PF00069	0.484
MOD_Plk_4	146	152	PF00069	0.491
MOD_Plk_4	175	181	PF00069	0.484
MOD_Plk_4	336	342	PF00069	0.502
MOD_Plk_4	363	369	PF00069	0.502
MOD_ProDKin_1	169	175	PF00069	0.484
MOD_ProDKin_1	216	222	PF00069	0.435
TRG_DiLeu_BaEn_1	108	113	PF01217	0.484
TRG_ENDOCYTIC_2	281	284	PF00928	0.484
TRG_ENDOCYTIC_2	81	84	PF00928	0.484
TRG_ER_diArg_1	317	320	PF00400	0.502
TRG_ER_diArg_1	378	380	PF00400	0.509
TRG_ER_diArg_1	389	391	PF00400	0.470

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P449	Leptomonas seymouri	31%	94%
A0A0N0P7H2	Leptomonas seymouri	35%	99%
A0A0N1HR67	Leptomonas seymouri	40%	98%
A0A0S4J7M4	Bodo saltans	35%	98%
A0A0S4JK93	Bodo saltans	24%	77%
A0A0S4KPM6	Bodo saltans	30%	93%
A0A1X0NLP3	Trypanosomatidae	35%	99%
A0A1X0NXK9	Trypanosomatidae	96%	100%
A0A1X0NXS7	Trypanosomatidae	29%	90%
A0A381MCS3	Leishmania infantum	40%	98%
A0A381MS01	Leishmania infantum	100%	100%
A0A3Q8IAD6	Leishmania donovani	31%	94%
A0A3Q8IDE9	Leishmania donovani	35%	99%
A0A3Q8IFB7	Leishmania donovani	99%	100%
A0A3Q8IM37	Leishmania donovani	100%	100%
A0A3R7KU60	Trypanosoma rangeli	32%	93%
A0A3S5H697	Leishmania donovani	99%	100%
A0A3S5H6A0	Leishmania donovani	99%	100%
A0A3S5H6N2	Leishmania donovani	40%	98%
A0A3S5H7U1	Leishmania donovani	100%	100%
A0A422NXM1	Trypanosoma rangeli	36%	99%
A0AAL4	Dictyostelium purpureum	40%	100%
A2AQ07	Mus musculus	73%	98%
A4H727	Leishmania braziliensis	40%	98%
A4HBW1	Leishmania braziliensis	30%	94%
A4HC48	Leishmania braziliensis	98%	100%
A4HE31	Leishmania braziliensis	35%	99%
A4HLC8	Leishmania braziliensis	100%	100%
A4HLC9	Leishmania braziliensis	99%	100%
A4HTR0	Leishmania infantum	99%	100%
A4HTR1	Leishmania infantum	100%	100%
A4HZJ3	Leishmania infantum	99%	100%
A4I1D7	Leishmania infantum	35%	99%
A5A6J1	Pan troglodytes	42%	98%
A6NHL2	Homo sapiens	40%	99%
A6NNZ2	Homo sapiens	81%	100%
B9DGT7	Arabidopsis thaliana	42%	98%
B9DHQ0	Arabidopsis thaliana	41%	98%
C9ZIG2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	95%	100%
C9ZIG3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	98%
C9ZIG6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZIG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	93%	100%
C9ZJV2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	99%
D0A1A1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	91%
E8NHR0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9AGK7	Leishmania infantum	40%	90%
E9AGW9	Leishmania infantum	31%	94%
E9AMJ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9AMJ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
E9AP62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	81%
E9AV85	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	94%
E9AVI3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9AXH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	99%
E9B3R4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	90%
O04386	Chlamydomonas incerta	88%	100%
O17449	Manduca sexta	84%	99%
O22347	Eleusine indica	42%	98%
O22348	Eleusine indica	41%	99%
O22349	Eleusine indica	40%	98%
O42786	Dothistroma septosporum	78%	99%
O44388	Trichuris trichiura	85%	100%
O49068	Oryza sativa subsp. japonica	35%	94%
O59837	Phytophthora cinnamomi	87%	100%
O93807	Candida albicans	28%	88%
O94128	Zymoseptoria tritici	40%	98%
P02550	Sus scrofa	42%	98%
P02552	Gallus gallus	43%	100%
P02554	Sus scrofa	86%	100%
P02557	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	72%	97%
P04105	Physarum polycephalum	42%	99%
P04106	Trypanosoma brucei rhodesiense	41%	98%
P04107	Trypanosoma brucei rhodesiense	95%	100%
P04350	Homo sapiens	85%	100%
P04688	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	97%
P04689	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	99%
P04690	Chlamydomonas reinhardtii	88%	100%
P05213	Mus musculus	43%	98%
P05214	Mus musculus	42%	98%
P05219	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	74%	99%
P05220	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	79%	99%
P05304	Giardia intestinalis	83%	99%
P06603	Drosophila melanogaster	42%	98%
P06604	Drosophila melanogaster	41%	99%
P06605	Drosophila melanogaster	42%	98%
P06606	Drosophila melanogaster	39%	96%
P07304	Stylonychia lemnae	41%	100%
P07436	Physarum polycephalum	87%	95%
P07437	Homo sapiens	86%	100%
P08070	Gallus gallus	40%	99%
P08537	Xenopus laevis	42%	99%
P08562	Trypanosoma cruzi	95%	100%
P08841	Drosophila melanogaster	80%	98%
P09203	Gallus gallus	86%	100%
P09204	Chlamydomonas reinhardtii	41%	98%
P09205	Chlamydomonas reinhardtii	41%	98%
P09206	Gallus gallus	86%	100%
P09207	Gallus gallus	78%	99%
P09243	Stylonychia lemnae	42%	99%
P09244	Gallus gallus	86%	100%
P09642	Gallus gallus	40%	100%
P09643	Gallus gallus	39%	100%
P09644	Gallus gallus	42%	99%
P09645	Gallus gallus	38%	100%
P09652	Gallus gallus	82%	99%
P09653	Gallus gallus	83%	99%
P09733	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	99%
P09734	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	100%
P0DPH7	Homo sapiens	42%	98%
P0DPH8	Homo sapiens	42%	98%
P10653	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	78%	99%
P10872	Tetrahymena pyriformis	43%	99%
P10873	Toxoplasma gondii	42%	98%
P10874	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	75%	99%
P10875	Candida albicans	72%	99%
P10876	Tetrahymena pyriformis	89%	100%
P10878	Toxoplasma gondii	88%	99%
P11139	Arabidopsis thaliana	41%	98%
P11237	Naegleria gruberi	42%	98%
P11480	Physarum polycephalum	43%	99%
P11481	Volvox carteri	41%	98%
P11482	Volvox carteri	88%	100%
P11833	Paracentrotus lividus	86%	99%
P11857	Stylonychia lemnae	90%	100%
P12411	Arabidopsis thaliana	86%	99%
P12456	Caenorhabditis elegans	84%	100%
P12457	Euglena gracilis	88%	100%
P12458	Physarum polycephalum	78%	98%
P12459	Glycine max	82%	100%
P12460	Glycine max	85%	99%
P12543	Plasmodium yoelii yoelii	42%	98%
P13602	Xenopus laevis	85%	100%
P14140	Plasmodium falciparum	86%	100%
P14640	Zea mays	42%	98%
P14641	Zea mays	42%	98%
P14642	Plasmodium falciparum (isolate K1 / Thailand)	42%	98%
P14643	Plasmodium falciparum (isolate K1 / Thailand)	86%	100%
P16040	Blumeria hordei	78%	99%
P17938	Epichloe typhina	79%	99%
P18025	Zea mays	85%	99%
P18026	Zea mays	86%	100%
P18241	Brugia pahangi	81%	99%
P18258	Paracentrotus lividus	41%	98%
P18288	Oncorhynchus mykiss	41%	98%
P18695	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	98%
P20364	Daucus carota	86%	100%
P20365	Euplotes crassus	89%	99%
P20802	Achlya klebsiana	87%	100%
P21148	Leishmania mexicana	98%	100%
P22012	Aspergillus flavus	78%	99%
P22013	Colletotrichum graminicola	71%	100%
P22014	Colletotrichum graminicola	79%	99%
P22275	Zea mays	41%	98%
P22852	Polytomella agilis	87%	100%
P23257	Drosophila melanogaster	34%	93%
P23258	Homo sapiens	35%	98%
P23330	Xenopus laevis	34%	98%
P24633	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	40%	99%
P24634	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	40%	98%
P24636	Arabidopsis thaliana	85%	100%
P24637	Pneumocystis carinii	78%	100%
P25295	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	99%
P25862	Avena sativa	88%	100%
P28268	Euplotes vannus	43%	98%
P28287	Oxytricha granulifera	42%	98%
P28551	Glycine max	87%	100%
P28752	Oryza sativa subsp. japonica	41%	98%
P29500	Pisum sativum	85%	98%
P29501	Pisum sativum	86%	99%
P29502	Pisum sativum	86%	100%
P29511	Arabidopsis thaliana	42%	98%
P29513	Arabidopsis thaliana	85%	99%
P29514	Arabidopsis thaliana	86%	99%
P29515	Arabidopsis thaliana	86%	99%
P29516	Arabidopsis thaliana	85%	99%
P29517	Arabidopsis thaliana	86%	100%
P30156	Ectocarpus variabilis	85%	99%
P30157	Ectocarpus variabilis	85%	99%
P30436	Oncorhynchus keta	42%	98%
P30668	Schizophyllum commune	79%	100%
P30883	Xenopus laevis	86%	100%
P31017	Entamoeba histolytica	37%	97%
P31863	Hypocrea rufa	77%	99%
P31864	Hypocrea rufa	74%	99%
P32255	Dictyostelium discoideum	42%	97%
P32256	Dictyostelium discoideum	75%	97%
P32348	Microbotryum violaceum	36%	94%
P32882	Gallus gallus	86%	100%
P32924	Geotrichum candidum	73%	99%
P32925	Geotrichum candidum	60%	98%
P32928	Colletotrichum gloeosporioides	69%	99%
P33127	Epichloe coenophiala	79%	99%
P33188	Paramecium tetraurelia	90%	100%
P33623	Anemia phyllitidis	42%	98%
P33624	Anemia phyllitidis	41%	100%
P33625	Euglena gracilis	43%	98%
P33627	Zea mays	41%	98%
P33629	Prunus dulcis	42%	98%
P33630	Anemia phyllitidis	84%	100%
P33631	Anemia phyllitidis	86%	100%
P34108	Naegleria pringsheimi	89%	98%
P34475	Caenorhabditis elegans	31%	100%
P34690	Caenorhabditis elegans	41%	99%
P34785	Anemia phyllitidis	34%	94%
P34786	Euplotoides octocarinatus	34%	96%
P34787	Plasmodium falciparum (isolate NF54)	33%	98%
P35394	Enteroctopus dofleini	79%	99%
P36220	Torpedo marmorata	42%	98%
P36221	Notothenia neglecta	85%	99%
P37392	Lupinus albus	85%	99%
P37832	Oryza sativa subsp. japonica	87%	100%
P38557	Arabidopsis thaliana	34%	93%
P38558	Arabidopsis thaliana	35%	93%
P38668	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	40%	98%
P38669	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	40%	99%
P40633	Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O)	34%	97%
P40904	Colletotrichum gloeosporioides	79%	99%
P40905	Erysiphe pisi	78%	99%
P41351	Tetrahymena thermophila	43%	99%
P41352	Tetrahymena thermophila	90%	100%
P41383	Patella vulgata	41%	98%
P41385	Bombyx mori	75%	98%
P41386	Haliotis discus	87%	100%
P41387	Onchocerca gibsoni	83%	100%
P41388	Venturia inaequalis	79%	99%
P41741	Acremonium chrysogenum	78%	99%
P41742	Ajellomyces capsulatus	76%	100%
P41799	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	78%	99%
P41937	Caenorhabditis elegans	84%	100%
P42271	Drosophila melanogaster	33%	97%
P45960	Oryza sativa subsp. japonica	86%	99%
P46259	Pisum sativum	42%	98%
P46263	Solanum tuberosum	85%	98%
P46264	Solanum tuberosum	85%	98%
P46265	Oryza sativa subsp. japonica	87%	99%
P49741	Schizophyllum commune	41%	99%
P49742	Schizophyllum commune	41%	99%
P50258	Physarum polycephalum	42%	98%
P50259	Porphyra purpurea	73%	97%
P50260	Oomycete-like sp. (strain MacKay2000)	89%	100%
P50261	Oomycete-like sp. (strain MacKay2000)	85%	100%
P50262	Oomycete-like sp. (strain MacKay2000)	87%	98%
P50719	Haemonchus contortus	42%	98%
P52273	Bombyx mori	41%	98%
P52274	Caenorhabditis elegans	41%	98%
P52275	Caenorhabditis elegans	80%	98%
P53371	Ajellomyces capsulatus	39%	100%
P53372	Pneumocystis carinii	42%	99%
P53373	Botryotinia fuckeliana	79%	99%
P53374	Gibberella fujikuroi	79%	99%
P53375	Penicillium digitatum	77%	99%
P53376	Rhynchosporium secalis	79%	99%
P53377	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	34%	96%
P53378	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	94%
P54401	Entamoeba histolytica	32%	98%
P54402	Euplotes aediculatus	34%	96%
P54403	Euplotes crassus	35%	96%
P54404	Euplotes crassus	36%	96%
P54405	Reticulomyxa filosa	34%	93%
P61857	Drosophila melanogaster	84%	99%
P61858	Drosophila hydei	84%	99%
P68360	Meriones unguiculatus	43%	98%
P68361	Cricetulus griseus	43%	98%
P68362	Cricetulus griseus	42%	98%
P68363	Homo sapiens	43%	98%
P68365	Cricetulus griseus	42%	99%
P68366	Homo sapiens	42%	99%
P68367	Macaca fascicularis	42%	99%
P68368	Mus musculus	42%	99%
P68369	Mus musculus	42%	98%
P68370	Rattus norvegicus	42%	98%
P68371	Homo sapiens	86%	100%
P68372	Mus musculus	86%	100%
P68373	Mus musculus	42%	99%
P69893	Cricetulus griseus	86%	100%
P69895	Macaca mulatta	86%	100%
P69897	Rattus norvegicus	86%	100%
P79008	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)	80%	100%
P81947	Bos taurus	43%	98%
P81948	Bos taurus	42%	99%
P83130	Drosophila erecta	84%	99%
P83887	Mus musculus	34%	98%
P83888	Rattus norvegicus	34%	98%
P85108	Rattus norvegicus	86%	100%
P87066	Candida albicans	43%	99%
P90548	Euplotoides octocarinatus	34%	96%
P91910	Caenorhabditis elegans	41%	98%
P92120	Encephalitozoon hellem	39%	100%
P93176	Hordeum vulgare	86%	99%
P99024	Mus musculus	86%	100%
Q00264	Aspergillus parasiticus	78%	99%
Q02245	Zea mays	41%	98%
Q04709	Babesia bovis	86%	100%
Q06331	Enteroctopus dofleini	41%	98%
Q08114	Euplotoides octocarinatus	42%	98%
Q08115	Euplotoides octocarinatus	89%	100%
Q0VCD2	Bos taurus	34%	98%
Q0WV25	Arabidopsis thaliana	42%	98%
Q13509	Homo sapiens	82%	98%
Q13885	Homo sapiens	86%	100%
Q17299	Caenorhabditis briggsae	84%	100%
Q24560	Drosophila melanogaster	85%	99%
Q24829	Encephalitozoon hellem	74%	100%
Q25008	Homarus americanus	41%	98%
Q25009	Homarus americanus	81%	98%
Q25563	Naegleria pringsheimi	42%	98%
Q27352	Trypanosoma cruzi	41%	98%
Q27380	Eimeria tenella	87%	99%
Q27U48	Glossina morsitans morsitans	85%	99%
Q28IX8	Xenopus tropicalis	42%	99%
Q2HJ81	Bos taurus	84%	99%
Q2HJ86	Bos taurus	43%	98%
Q2HJB8	Bos taurus	41%	99%
Q2KJD0	Bos taurus	86%	100%
Q2T9S0	Bos taurus	82%	98%
Q2U2U3	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	78%	99%
Q2XVP4	Sus scrofa	43%	98%
Q32KM1	Bos taurus	34%	98%
Q32KN8	Bos taurus	41%	98%
Q38771	Avena sativa	40%	99%
Q39445	Cicer arietinum	85%	99%
Q39582	Chlamydomonas reinhardtii	33%	95%
Q39697	Daucus carota	84%	100%
Q3KRE8	Rattus norvegicus	86%	100%
Q3KVN1	Cercospora beticola	78%	99%
Q3MHM5	Bos taurus	86%	100%
Q3UX10	Mus musculus	40%	99%
Q3ZBU7	Bos taurus	85%	100%
Q3ZCJ7	Bos taurus	42%	99%
Q3ZCM7	Homo sapiens	83%	100%
Q40106	Lupinus albus	85%	99%
Q40665	Oryza sativa subsp. japonica	87%	99%
Q40831	Pelvetia fastigiata	41%	98%
Q40832	Pelvetia fastigiata	42%	98%
Q41782	Zea mays	83%	99%
Q41783	Zea mays	86%	99%
Q41784	Zea mays	86%	100%
Q41785	Zea mays	86%	100%
Q41807	Zea mays	34%	94%
Q41808	Zea mays	34%	94%
Q41874	Zea mays	33%	100%
Q42480	Chondrus crispus	66%	98%
Q43473	Hordeum vulgare	41%	98%
Q43594	Oryza sativa subsp. japonica	86%	99%
Q43695	Zea mays	85%	100%
Q43697	Zea mays	86%	100%
Q4HZS8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	79%	99%
Q4P235	Ustilago maydis (strain 521 / FGSC 9021)	76%	99%
Q4Q9Z8	Leishmania major	35%	100%
Q4QBZ6	Leishmania major	99%	100%
Q4QC95	Leishmania major	31%	94%
Q4QGC5	Leishmania major	40%	98%
Q4QI42	Leishmania major	99%	100%
Q4QRB4	Rattus norvegicus	82%	98%
Q4R4X8	Macaca fascicularis	85%	100%
Q4R538	Macaca fascicularis	43%	98%
Q4R5B3	Macaca fascicularis	86%	100%
Q4R7T7	Macaca fascicularis	26%	98%
Q4R9N3	Cochliobolus heterostrophus	78%	99%
Q4WA70	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	73%	99%
Q52NY7	Metarhizium anisopliae	79%	99%
Q52PV9	Tyrophagus putrescentiae	41%	98%
Q53M52	Oryza sativa subsp. japonica	42%	98%
Q55AR3	Dictyostelium discoideum	35%	96%
Q56WH1	Arabidopsis thaliana	41%	98%
Q56YW9	Arabidopsis thaliana	86%	98%
Q5I2J3	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	40%	99%
Q5R1W4	Pan troglodytes	43%	98%
Q5R943	Pongo abelii	86%	100%
Q5UBX3	Trichophyton rubrum	74%	99%
Q5XIF6	Rattus norvegicus	42%	99%
Q60HC2	Macaca fascicularis	82%	98%
Q68FR8	Rattus norvegicus	42%	98%
Q6AY56	Rattus norvegicus	41%	99%
Q6AYZ1	Rattus norvegicus	42%	99%
Q6B856	Bos taurus	86%	100%
Q6DIM3	Xenopus tropicalis	27%	98%
Q6EVK8	Suillus bovinus	79%	99%
Q6FNU9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	30%	95%
Q6GLE7	Xenopus tropicalis	86%	100%
Q6P9T8	Rattus norvegicus	86%	100%
Q6P9V9	Rattus norvegicus	43%	98%
Q6PEY2	Homo sapiens	42%	98%
Q6QDC9	Zymoseptoria tritici	77%	99%
Q6VAF4	Gossypium hirsutum	85%	100%
Q6VAF5	Gossypium hirsutum	83%	100%
Q6VAF6	Gossypium hirsutum	86%	98%
Q6VAF7	Gossypium hirsutum	86%	100%
Q6VAF8	Gossypium hirsutum	85%	100%
Q6VAF9	Gossypium hirsutum	42%	98%
Q6VAG0	Gossypium hirsutum	42%	98%
Q6VAG1	Gossypium hirsutum	42%	98%
Q71G51	Neospora caninum	42%	98%
Q71U36	Homo sapiens	42%	98%
Q752Y2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	41%	99%
Q75A43	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	33%	94%
Q767L7	Sus scrofa	86%	100%
Q76FS2	Oryza sativa subsp. japonica	85%	99%
Q76FS3	Oryza sativa subsp. japonica	86%	100%
Q7JJU6	Pan troglodytes	86%	100%
Q7KQL5	Plasmodium falciparum (isolate 3D7)	86%	100%
Q7TMM9	Mus musculus	86%	100%
Q7Z9Z2	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)	33%	98%
Q84TG9	Neopyropia yezoensis	73%	97%
Q86ZP5	Uncinula necator	78%	99%
Q875L2	Hypocrea virens	77%	99%
Q875L3	Hypocrea virens	77%	100%
Q8H7U1	Oryza sativa subsp. japonica	85%	99%
Q8HZV4	Canis lupus familiaris	25%	98%
Q8J1R4	Suillus bovinus	59%	100%
Q8SRD2	Encephalitozoon cuniculi (strain GB-M1)	31%	100%
Q8SRI6	Encephalitozoon cuniculi (strain GB-M1)	40%	100%
Q8SS99	Encephalitozoon cuniculi (strain GB-M1)	75%	100%
Q8T6A5	Aplysia californica	42%	98%
Q8VCK3	Mus musculus	34%	98%
Q8WP13	Papio hamadryas	82%	100%
Q8WP14	Pan troglodytes	82%	100%
Q8WQ47	Lepidoglyphus destructor	41%	98%
Q8WZE0	Microbotryum violaceum	76%	100%
Q91060	Notophthalmus viridescens	42%	98%
Q91240	Pseudopleuronectes americanus	85%	100%
Q91575	Xenopus laevis	86%	100%
Q92268	Pleurotus sajor-caju	78%	99%
Q922F4	Mus musculus	83%	99%
Q92335	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)	40%	99%
Q94570	Homarus americanus	40%	98%
Q94571	Homarus americanus	80%	98%
Q94572	Homarus americanus	41%	98%
Q962P8	Naegleria pringsheimi	39%	98%
Q96460	Hordeum vulgare	42%	98%
Q96TU8	Uromyces fabae	79%	99%
Q9ASR0	Arabidopsis thaliana	86%	98%
Q9BQE3	Homo sapiens	42%	99%
Q9BUF5	Homo sapiens	82%	99%
Q9BVA1	Homo sapiens	86%	100%
Q9C413	Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)	39%	98%
Q9CWF2	Mus musculus	86%	100%
Q9D6F9	Mus musculus	85%	100%
Q9D6T1	Mus musculus	34%	93%
Q9ERD7	Mus musculus	82%	98%
Q9FT36	Daucus carota	42%	98%
Q9GKK5	Canis lupus familiaris	34%	98%
Q9GSR5	Encephalitozoon intestinalis	74%	100%
Q9H4B7	Homo sapiens	74%	98%
Q9HFQ3	Melampsora lini	80%	99%
Q9JJZ2	Mus musculus	41%	99%
Q9LKI8	Thalassiosira weissflogii	84%	100%
Q9N2N6	Euplotes focardii	89%	100%
Q9NFZ5	Echinococcus multilocularis	74%	100%
Q9NFZ6	Echinococcus multilocularis	86%	100%
Q9NFZ7	Echinococcus multilocularis	85%	99%
Q9NRH3	Homo sapiens	35%	98%
Q9NY65	Homo sapiens	42%	99%
Q9R1K7	Mus musculus	26%	97%
Q9SCC8	Guillardia theta	41%	99%
Q9SEA4	Guillardia theta	24%	100%
Q9SEV2	Guillardia theta	77%	100%
Q9UJT0	Homo sapiens	35%	93%
Q9UJT1	Homo sapiens	25%	98%
Q9UV72	Pestalotiopsis microspora	79%	99%
Q9VRX3	Drosophila melanogaster	54%	96%
Q9XFG3	Physcomitrium patens	34%	93%
Q9Y882	Schizosaccharomyces japonicus	36%	99%
Q9YHC3	Gadus morhua	85%	100%
Q9ZPN7	Eleusine indica	86%	99%
Q9ZPN8	Eleusine indica	87%	99%
Q9ZPN9	Eleusine indica	85%	99%
Q9ZPP0	Eleusine indica	86%	100%
Q9ZRA8	Triticum aestivum	85%	99%
Q9ZRA9	Triticum aestivum	85%	100%
Q9ZRB0	Triticum aestivum	86%	100%
Q9ZRB1	Triticum aestivum	86%	99%
Q9ZRB2	Triticum aestivum	85%	100%
Q9ZRB7	Triticum aestivum	42%	98%
Q9ZRJ4	Chlorella vulgaris	42%	98%
Q9ZRR5	Hordeum vulgare	42%	98%
Q9ZSW1	Cyanophora paradoxa	89%	99%
R9TL42	Trypanosoma rangeli	96%	100%
R9TNG7	Trypanosoma rangeli	41%	98%
V5AR05	Trypanosoma cruzi	32%	93%
V5DCF0	Trypanosoma cruzi	35%	99%