LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q4A5_LEIMA
TriTrypDb:
LmjF.33.0870 , LMJLV39_330015800 * , LMJSD75_330015600 *
Length:
492

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4A5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4A5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 215 219 PF00656 0.505
CLV_C14_Caspase3-7 365 369 PF00656 0.618
CLV_C14_Caspase3-7 69 73 PF00656 0.677
CLV_MEL_PAP_1 259 265 PF00089 0.525
CLV_NRD_NRD_1 19 21 PF00675 0.444
CLV_NRD_NRD_1 281 283 PF00675 0.529
CLV_NRD_NRD_1 331 333 PF00675 0.693
CLV_NRD_NRD_1 40 42 PF00675 0.447
CLV_NRD_NRD_1 433 435 PF00675 0.402
CLV_NRD_NRD_1 474 476 PF00675 0.390
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PBA2 Leptomonas seymouri 43% 100%
A0A3Q8ITX1 Leishmania donovani 93% 100%
A4HLE1 Leishmania braziliensis 74% 100%
A4I8V0 Leishmania infantum 93% 100%
E9B3R9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS