LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q498_LEIMA
TriTrypDb:
LmjF.33.0935 , LMJLV39_330016500 * , LMJSD75_330016300 *
Length:
548

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q498
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q498

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 111 113 PF00675 0.720
CLV_NRD_NRD_1 126 128 PF00675 0.669
CLV_NRD_NRD_1 153 155 PF00675 0.539
CLV_NRD_NRD_1 19 21 PF00675 0.593
CLV_NRD_NRD_1 191 193 PF00675 0.647
CLV_NRD_NRD_1 204 206 PF00675 0.490
CLV_NRD_NRD_1 280 282 PF00675 0.674
CLV_NRD_NRD_1 283 285 PF00675 0.657
CLV_NRD_NRD_1 287 289 PF00675 0.616
CLV_NRD_NRD_1 293 295 PF00675 0.557
CLV_NRD_NRD_1 33 35 PF00675 0.593
CLV_NRD_NRD_1 349 351 PF00675 0.580
CLV_PCSK_FUR_1 189 193 PF00082 0.656
CLV_PCSK_FUR_1 281 285 PF00082 0.680
CLV_PCSK_FUR_1 288 292 PF00082 0.616
CLV_PCSK_KEX2_1 111 113 PF00082 0.720
CLV_PCSK_KEX2_1 153 155 PF00082 0.539
CLV_PCSK_KEX2_1 19 21 PF00082 0.593
CLV_PCSK_KEX2_1 191 193 PF00082 0.647
CLV_PCSK_KEX2_1 203 205 PF00082 0.515
CLV_PCSK_KEX2_1 222 224 PF00082 0.486
CLV_PCSK_KEX2_1 280 282 PF00082 0.674
CLV_PCSK_KEX2_1 283 285 PF00082 0.657
CLV_PCSK_KEX2_1 286 288 PF00082 0.634
CLV_PCSK_KEX2_1 290 292 PF00082 0.589
CLV_PCSK_KEX2_1 293 295 PF00082 0.557
CLV_PCSK_KEX2_1 33 35 PF00082 0.617
CLV_PCSK_KEX2_1 337 339 PF00082 0.545
CLV_PCSK_PC1ET2_1 222 224 PF00082 0.629
CLV_PCSK_PC1ET2_1 290 292 PF00082 0.639
CLV_PCSK_PC1ET2_1 337 339 PF00082 0.545
CLV_PCSK_PC7_1 283 289 PF00082 0.687
CLV_PCSK_PC7_1 29 35 PF00082 0.592
CLV_PCSK_SKI1_1 205 209 PF00082 0.604
CLV_PCSK_SKI1_1 219 223 PF00082 0.574
CLV_PCSK_SKI1_1 350 354 PF00082 0.660
CLV_PCSK_SKI1_1 382 386 PF00082 0.799
CLV_PCSK_SKI1_1 524 528 PF00082 0.659
CLV_PCSK_SKI1_1 60 64 PF00082 0.503
DEG_APCC_DBOX_1 144 152 PF00400 0.572
DEG_APCC_DBOX_1 178 186 PF00400 0.654
DEG_APCC_DBOX_1 204 212 PF00400 0.576
DEG_SPOP_SBC_1 420 424 PF00917 0.691
DEG_SPOP_SBC_1 469 473 PF00917 0.592
DOC_CYCLIN_yCln2_LP_2 114 120 PF00134 0.636
DOC_MAPK_gen_1 142 151 PF00069 0.483
DOC_MAPK_gen_1 191 201 PF00069 0.686
DOC_MAPK_gen_1 350 360 PF00069 0.650
DOC_MAPK_JIP1_4 195 201 PF00069 0.587
DOC_MAPK_MEF2A_6 45 53 PF00069 0.580
DOC_USP7_MATH_1 170 174 PF00917 0.525
DOC_USP7_MATH_1 241 245 PF00917 0.693
DOC_USP7_MATH_1 32 36 PF00917 0.604
DOC_USP7_MATH_1 367 371 PF00917 0.699
DOC_USP7_MATH_1 462 466 PF00917 0.737
DOC_USP7_MATH_1 474 478 PF00917 0.650
DOC_USP7_MATH_1 483 487 PF00917 0.637
DOC_USP7_MATH_1 496 500 PF00917 0.579
DOC_USP7_MATH_1 504 508 PF00917 0.691
DOC_USP7_MATH_1 78 82 PF00917 0.557
DOC_WW_Pin1_4 137 142 PF00397 0.644
DOC_WW_Pin1_4 2 7 PF00397 0.719
DOC_WW_Pin1_4 338 343 PF00397 0.715
DOC_WW_Pin1_4 389 394 PF00397 0.594
DOC_WW_Pin1_4 406 411 PF00397 0.582
DOC_WW_Pin1_4 477 482 PF00397 0.668
DOC_WW_Pin1_4 74 79 PF00397 0.598
LIG_14-3-3_CanoR_1 179 183 PF00244 0.735
LIG_14-3-3_CanoR_1 223 228 PF00244 0.744
LIG_14-3-3_CanoR_1 243 247 PF00244 0.455
LIG_14-3-3_CanoR_1 338 342 PF00244 0.669
LIG_14-3-3_CanoR_1 45 53 PF00244 0.580
LIG_14-3-3_CanoR_1 60 68 PF00244 0.484
LIG_Actin_WH2_2 321 339 PF00022 0.534
LIG_Actin_WH2_2 367 383 PF00022 0.692
LIG_BIR_III_4 438 442 PF00653 0.562
LIG_BRCT_BRCA1_1 3 7 PF00533 0.618
LIG_BRCT_BRCA1_1 54 58 PF00533 0.585
LIG_eIF4E_1 143 149 PF01652 0.579
LIG_FHA_1 26 32 PF00498 0.608
LIG_FHA_1 327 333 PF00498 0.711
LIG_FHA_1 338 344 PF00498 0.585
LIG_FHA_1 401 407 PF00498 0.630
LIG_FHA_1 422 428 PF00498 0.684
LIG_FHA_1 471 477 PF00498 0.656
LIG_FHA_1 482 488 PF00498 0.600
LIG_FHA_1 509 515 PF00498 0.561
LIG_FHA_2 182 188 PF00498 0.594
LIG_LIR_Gen_1 10 17 PF02991 0.696
LIG_LIR_Gen_1 140 151 PF02991 0.709
LIG_LIR_Nem_3 10 15 PF02991 0.692
LIG_LIR_Nem_3 140 146 PF02991 0.724
LIG_PDZ_Class_2 543 548 PF00595 0.605
LIG_Pex14_2 7 11 PF04695 0.572
LIG_PTAP_UEV_1 497 502 PF05743 0.639
LIG_SH3_2 376 381 PF14604 0.683
LIG_SH3_2 498 503 PF14604 0.687
LIG_SH3_3 114 120 PF00018 0.636
LIG_SH3_3 135 141 PF00018 0.603
LIG_SH3_3 373 379 PF00018 0.595
LIG_SH3_3 426 432 PF00018 0.679
LIG_SH3_3 490 496 PF00018 0.740
LIG_TRAF2_2 432 437 PF00917 0.547
MOD_CDK_SPK_2 137 142 PF00069 0.519
MOD_CK1_1 165 171 PF00069 0.607
MOD_CK1_1 178 184 PF00069 0.502
MOD_CK1_1 197 203 PF00069 0.470
MOD_CK1_1 250 256 PF00069 0.725
MOD_CK1_1 326 332 PF00069 0.760
MOD_CK1_1 430 436 PF00069 0.661
MOD_CK1_1 465 471 PF00069 0.643
MOD_CK1_1 477 483 PF00069 0.619
MOD_CK1_1 486 492 PF00069 0.639
MOD_CK1_1 5 11 PF00069 0.610
MOD_CK1_1 509 515 PF00069 0.711
MOD_CK1_1 81 87 PF00069 0.749
MOD_CK2_1 181 187 PF00069 0.602
MOD_CK2_1 241 247 PF00069 0.586
MOD_CK2_1 293 299 PF00069 0.672
MOD_CK2_1 7 13 PF00069 0.576
MOD_DYRK1A_RPxSP_1 338 342 PF00069 0.620
MOD_GlcNHglycan 100 104 PF01048 0.443
MOD_GlcNHglycan 165 168 PF01048 0.651
MOD_GlcNHglycan 247 250 PF01048 0.571
MOD_GlcNHglycan 268 271 PF01048 0.571
MOD_GlcNHglycan 314 317 PF01048 0.649
MOD_GlcNHglycan 355 358 PF01048 0.652
MOD_GlcNHglycan 376 379 PF01048 0.679
MOD_GlcNHglycan 410 413 PF01048 0.643
MOD_GlcNHglycan 464 467 PF01048 0.754
MOD_GlcNHglycan 476 479 PF01048 0.672
MOD_GlcNHglycan 489 492 PF01048 0.737
MOD_GlcNHglycan 498 501 PF01048 0.635
MOD_GlcNHglycan 54 57 PF01048 0.535
MOD_GlcNHglycan 7 10 PF01048 0.549
MOD_GlcNHglycan 84 87 PF01048 0.596
MOD_GSK3_1 1 8 PF00069 0.630
MOD_GSK3_1 11 18 PF00069 0.530
MOD_GSK3_1 177 184 PF00069 0.580
MOD_GSK3_1 241 248 PF00069 0.659
MOD_GSK3_1 319 326 PF00069 0.758
MOD_GSK3_1 332 339 PF00069 0.583
MOD_GSK3_1 358 365 PF00069 0.637
MOD_GSK3_1 389 396 PF00069 0.590
MOD_GSK3_1 408 415 PF00069 0.635
MOD_GSK3_1 465 472 PF00069 0.753
MOD_GSK3_1 477 484 PF00069 0.654
MOD_GSK3_1 504 511 PF00069 0.735
MOD_GSK3_1 52 59 PF00069 0.559
MOD_GSK3_1 74 81 PF00069 0.643
MOD_GSK3_1 85 92 PF00069 0.581
MOD_N-GLC_1 223 228 PF02516 0.594
MOD_N-GLC_1 304 309 PF02516 0.565
MOD_N-GLC_1 74 79 PF02516 0.560
MOD_NEK2_1 15 20 PF00069 0.555
MOD_NEK2_1 175 180 PF00069 0.635
MOD_NEK2_1 199 204 PF00069 0.562
MOD_NEK2_1 336 341 PF00069 0.629
MOD_NEK2_1 380 385 PF00069 0.694
MOD_NEK2_1 51 56 PF00069 0.517
MOD_NEK2_1 539 544 PF00069 0.650
MOD_NEK2_1 58 63 PF00069 0.531
MOD_NEK2_1 7 12 PF00069 0.610
MOD_NEK2_1 79 84 PF00069 0.632
MOD_NEK2_2 106 111 PF00069 0.434
MOD_NEK2_2 367 372 PF00069 0.554
MOD_PIKK_1 130 136 PF00454 0.624
MOD_PIKK_1 250 256 PF00454 0.561
MOD_PIKK_1 32 38 PF00454 0.613
MOD_PIKK_1 323 329 PF00454 0.674
MOD_PIKK_1 430 436 PF00454 0.621
MOD_PIKK_1 44 50 PF00454 0.458
MOD_PIKK_1 541 547 PF00454 0.604
MOD_PKA_1 19 25 PF00069 0.533
MOD_PKA_1 286 292 PF00069 0.688
MOD_PKA_1 293 299 PF00069 0.617
MOD_PKA_1 337 343 PF00069 0.546
MOD_PKA_1 350 356 PF00069 0.520
MOD_PKA_2 178 184 PF00069 0.618
MOD_PKA_2 19 25 PF00069 0.593
MOD_PKA_2 194 200 PF00069 0.542
MOD_PKA_2 228 234 PF00069 0.597
MOD_PKA_2 242 248 PF00069 0.570
MOD_PKA_2 286 292 PF00069 0.688
MOD_PKA_2 293 299 PF00069 0.617
MOD_PKA_2 32 38 PF00069 0.556
MOD_PKA_2 337 343 PF00069 0.696
MOD_PKA_2 427 433 PF00069 0.567
MOD_PKA_2 44 50 PF00069 0.458
MOD_PKA_2 509 515 PF00069 0.686
MOD_PKB_1 284 292 PF00069 0.687
MOD_Plk_1 223 229 PF00069 0.602
MOD_Plk_1 304 310 PF00069 0.541
MOD_Plk_4 380 386 PF00069 0.722
MOD_Plk_4 7 13 PF00069 0.607
MOD_Plk_4 89 95 PF00069 0.566
MOD_ProDKin_1 137 143 PF00069 0.640
MOD_ProDKin_1 2 8 PF00069 0.715
MOD_ProDKin_1 338 344 PF00069 0.715
MOD_ProDKin_1 389 395 PF00069 0.591
MOD_ProDKin_1 406 412 PF00069 0.580
MOD_ProDKin_1 477 483 PF00069 0.663
MOD_ProDKin_1 74 80 PF00069 0.599
TRG_ENDOCYTIC_2 143 146 PF00928 0.667
TRG_ER_diArg_1 110 112 PF00400 0.715
TRG_ER_diArg_1 152 154 PF00400 0.544
TRG_ER_diArg_1 189 192 PF00400 0.658
TRG_ER_diArg_1 203 205 PF00400 0.564
TRG_ER_diArg_1 279 281 PF00400 0.683
TRG_ER_diArg_1 283 286 PF00400 0.648
TRG_ER_diArg_1 291 294 PF00400 0.572
TRG_NES_CRM1_1 41 52 PF08389 0.552
TRG_NLS_Bipartite_1 280 294 PF00514 0.636
TRG_NLS_MonoCore_2 289 294 PF00514 0.562
TRG_NLS_MonoExtC_3 289 294 PF00514 0.637
TRG_NLS_MonoExtC_3 535 541 PF00514 0.577
TRG_NLS_MonoExtN_4 287 294 PF00514 0.639
TRG_PTS2 1 42 PF00400 0.625

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X6K5 Leishmania donovani 83% 100%
A4HLE8 Leishmania braziliensis 61% 100%
A4I8V7 Leishmania infantum 84% 100%
E9B3S6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS