LeishMANIAdb
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Rhodanese domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Rhodanese domain-containing protein
Gene product:
rhodanese-like domain containing protein, putative
Species:
Leishmania major
UniProt:
Q4Q492_LEIMA
TriTrypDb:
LmjF.33.0990 , LMJLV39_330017200 , LMJSD75_330017000
Length:
142

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 10
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q492
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q492

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 127 131 PF00082 0.296
DEG_APCC_DBOX_1 126 134 PF00400 0.496
DOC_MAPK_MEF2A_6 123 130 PF00069 0.496
DOC_PP4_FxxP_1 58 61 PF00568 0.496
DOC_WW_Pin1_4 117 122 PF00397 0.416
DOC_WW_Pin1_4 95 100 PF00397 0.465
LIG_BIR_II_1 1 5 PF00653 0.615
LIG_LIR_Apic_2 57 61 PF02991 0.507
LIG_LIR_Gen_1 135 142 PF02991 0.550
LIG_LIR_Gen_1 53 61 PF02991 0.493
LIG_LIR_Gen_1 70 81 PF02991 0.493
LIG_LIR_Nem_3 135 139 PF02991 0.496
LIG_LIR_Nem_3 53 58 PF02991 0.493
LIG_LIR_Nem_3 70 76 PF02991 0.493
LIG_PDZ_Class_2 137 142 PF00595 0.468
LIG_Pex14_1 136 140 PF04695 0.549
LIG_SH2_GRB2like 109 112 PF00017 0.493
LIG_SH2_STAT5 109 112 PF00017 0.493
LIG_SH2_STAT5 134 137 PF00017 0.520
LIG_SUMO_SIM_anti_2 43 48 PF11976 0.493
LIG_SUMO_SIM_par_1 43 48 PF11976 0.456
LIG_TRAF2_1 28 31 PF00917 0.493
LIG_TRAF2_1 67 70 PF00917 0.493
LIG_WRC_WIRS_1 55 60 PF05994 0.496
MOD_CDK_SPxK_1 117 123 PF00069 0.416
MOD_CK1_1 95 101 PF00069 0.455
MOD_CK2_1 25 31 PF00069 0.296
MOD_GlcNHglycan 21 24 PF01048 0.498
MOD_GlcNHglycan 27 30 PF01048 0.295
MOD_GlcNHglycan 94 97 PF01048 0.271
MOD_GSK3_1 113 120 PF00069 0.444
MOD_GSK3_1 134 141 PF00069 0.480
MOD_GSK3_1 36 43 PF00069 0.445
MOD_N-GLC_1 36 41 PF02516 0.237
MOD_PIKK_1 134 140 PF00454 0.476
MOD_PKA_2 6 12 PF00069 0.597
MOD_Plk_4 40 46 PF00069 0.547
MOD_ProDKin_1 117 123 PF00069 0.416
MOD_ProDKin_1 95 101 PF00069 0.465
TRG_ENDOCYTIC_2 55 58 PF00928 0.594

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1ILL9 Leptomonas seymouri 53% 100%
A0A0R6XWV6 Leishmania donovani 92% 99%
A0A0S4J1P4 Bodo saltans 30% 78%
A4I8W3 Leishmania infantum 94% 100%
E9B3T2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 99%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS