Putative calcium-transporting ATPase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

calcium-transporting ATPase, putative

Species:

Leishmania major

UniProt:

Q4Q490_LEIMA

TriTrypDb:

LmjF.33.1010 , LMJLV39_330017400 , LMJSD75_330017200

Length:

1194

Annotations

LeishMANIAdb annotations

Homologous to other eukaryotic P-type Ca2+ ATPases.. For some reason, this group has heavily expanded in Kinetoplastida.. Localization: Endosomal (by homology) / ER (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0005886	plasma membrane	3	3
GO:0016020	membrane	2	15
GO:0043226	organelle	2	4
GO:0043227	membrane-bounded organelle	3	4
GO:0043229	intracellular organelle	3	4
GO:0043231	intracellular membrane-bounded organelle	4	4
GO:0110165	cellular anatomical entity	1	15
GO:0005783	endoplasmic reticulum	5	1

Expansion

Sequence features

Q4Q490

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q490

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006816	calcium ion transport	7	1
GO:0006873	intracellular monoatomic ion homeostasis	4	1
GO:0006874	intracellular calcium ion homeostasis	7	1
GO:0006875	obsolete intracellular metal ion homeostasis	6	1
GO:0009987	cellular process	1	1
GO:0019725	cellular homeostasis	2	1
GO:0030001	metal ion transport	6	1
GO:0030003	intracellular monoatomic cation homeostasis	5	1
GO:0034220	monoatomic ion transmembrane transport	3	1
GO:0042592	homeostatic process	3	1
GO:0048878	chemical homeostasis	4	1
GO:0050801	monoatomic ion homeostasis	5	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0055065	obsolete metal ion homeostasis	7	1
GO:0055074	calcium ion homeostasis	8	1
GO:0055080	monoatomic cation homeostasis	6	1
GO:0055082	intracellular chemical homeostasis	3	1
GO:0055085	transmembrane transport	2	1
GO:0065007	biological regulation	1	1
GO:0065008	regulation of biological quality	2	1
GO:0070588	calcium ion transmembrane transport	6	1
GO:0072503	obsolete cellular divalent inorganic cation homeostasis	6	1
GO:0072507	obsolete divalent inorganic cation homeostasis	7	1
GO:0098655	monoatomic cation transmembrane transport	4	1
GO:0098660	inorganic ion transmembrane transport	4	1
GO:0098662	inorganic cation transmembrane transport	5	1
GO:0098771	inorganic ion homeostasis	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	15
GO:0003824	catalytic activity	1	15
GO:0005215	transporter activity	1	4
GO:0005388	P-type calcium transporter activity	4	4
GO:0005488	binding	1	15
GO:0005524	ATP binding	5	15
GO:0008324	monoatomic cation transmembrane transporter activity	4	4
GO:0015075	monoatomic ion transmembrane transporter activity	3	4
GO:0015085	calcium ion transmembrane transporter activity	6	4
GO:0015318	inorganic molecular entity transmembrane transporter activity	3	4
GO:0015399	primary active transmembrane transporter activity	4	4
GO:0015662	P-type ion transporter activity	4	4
GO:0016462	pyrophosphatase activity	5	15
GO:0016787	hydrolase activity	2	15
GO:0016817	hydrolase activity, acting on acid anhydrides	3	15
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	15
GO:0016887	ATP hydrolysis activity	7	15
GO:0017076	purine nucleotide binding	4	15
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	15
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3	4
GO:0022804	active transmembrane transporter activity	3	4
GO:0022853	active monoatomic ion transmembrane transporter activity	4	4
GO:0022857	transmembrane transporter activity	2	4
GO:0022890	inorganic cation transmembrane transporter activity	4	4
GO:0030554	adenyl nucleotide binding	5	15
GO:0032553	ribonucleotide binding	3	15
GO:0032555	purine ribonucleotide binding	4	15
GO:0032559	adenyl ribonucleotide binding	5	15
GO:0035639	purine ribonucleoside triphosphate binding	4	15
GO:0036094	small molecule binding	2	15
GO:0042626	ATPase-coupled transmembrane transporter activity	2	4
GO:0043167	ion binding	2	15
GO:0043168	anion binding	3	15
GO:0046873	metal ion transmembrane transporter activity	5	4
GO:0097159	organic cyclic compound binding	2	15
GO:0097367	carbohydrate derivative binding	2	15
GO:0140358	P-type transmembrane transporter activity	3	4
GO:0140657	ATP-dependent activity	1	4
GO:1901265	nucleoside phosphate binding	3	15
GO:1901363	heterocyclic compound binding	2	15

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	176	180	PF00656	0.697
CLV_C14_Caspase3-7	188	192	PF00656	0.639
CLV_C14_Caspase3-7	261	265	PF00656	0.448
CLV_C14_Caspase3-7	772	776	PF00656	0.723
CLV_NRD_NRD_1	1182	1184	PF00675	0.405
CLV_NRD_NRD_1	147	149	PF00675	0.409
CLV_NRD_NRD_1	165	167	PF00675	0.361
CLV_NRD_NRD_1	50	52	PF00675	0.320
CLV_NRD_NRD_1	560	562	PF00675	0.363
CLV_NRD_NRD_1	871	873	PF00675	0.251
CLV_NRD_NRD_1	938	940	PF00675	0.285
CLV_PCSK_FUR_1	1180	1184	PF00082	0.377
CLV_PCSK_FUR_1	558	562	PF00082	0.313
CLV_PCSK_KEX2_1	1165	1167	PF00082	0.472
CLV_PCSK_KEX2_1	1182	1184	PF00082	0.417
CLV_PCSK_KEX2_1	164	166	PF00082	0.393
CLV_PCSK_KEX2_1	5	7	PF00082	0.406
CLV_PCSK_KEX2_1	50	52	PF00082	0.322
CLV_PCSK_KEX2_1	560	562	PF00082	0.356
CLV_PCSK_KEX2_1	864	866	PF00082	0.324
CLV_PCSK_KEX2_1	871	873	PF00082	0.279
CLV_PCSK_KEX2_1	909	911	PF00082	0.248
CLV_PCSK_PC1ET2_1	1165	1167	PF00082	0.369
CLV_PCSK_PC1ET2_1	5	7	PF00082	0.404
CLV_PCSK_PC1ET2_1	864	866	PF00082	0.323
CLV_PCSK_PC1ET2_1	909	911	PF00082	0.248
CLV_PCSK_SKI1_1	1165	1169	PF00082	0.367
CLV_PCSK_SKI1_1	1175	1179	PF00082	0.377
CLV_PCSK_SKI1_1	1183	1187	PF00082	0.401
CLV_PCSK_SKI1_1	165	169	PF00082	0.347
CLV_PCSK_SKI1_1	248	252	PF00082	0.323
CLV_PCSK_SKI1_1	328	332	PF00082	0.357
CLV_PCSK_SKI1_1	377	381	PF00082	0.268
CLV_PCSK_SKI1_1	417	421	PF00082	0.311
CLV_PCSK_SKI1_1	482	486	PF00082	0.414
CLV_PCSK_SKI1_1	864	868	PF00082	0.354
CLV_PCSK_SKI1_1	932	936	PF00082	0.278
CLV_PCSK_SKI1_1	939	943	PF00082	0.306
CLV_Separin_Metazoa	155	159	PF03568	0.593
DEG_APCC_DBOX_1	1174	1182	PF00400	0.606
DEG_APCC_DBOX_1	49	57	PF00400	0.451
DEG_COP1_1	1006	1017	PF00400	0.506
DEG_MDM2_SWIB_1	1097	1105	PF02201	0.400
DEG_SPOP_SBC_1	174	178	PF00917	0.533
DOC_ANK_TNKS_1	686	693	PF00023	0.570
DOC_CKS1_1	109	114	PF01111	0.451
DOC_CYCLIN_RxL_1	935	947	PF00134	0.519
DOC_CYCLIN_yClb5_NLxxxL_5	380	389	PF00134	0.551
DOC_CYCLIN_yCln2_LP_2	251	257	PF00134	0.513
DOC_CYCLIN_yCln2_LP_2	578	584	PF00134	0.425
DOC_MAPK_gen_1	863	869	PF00069	0.509
DOC_MAPK_gen_1	909	917	PF00069	0.456
DOC_MAPK_MEF2A_6	115	123	PF00069	0.358
DOC_MAPK_MEF2A_6	971	980	PF00069	0.284
DOC_PP1_RVXF_1	938	945	PF00149	0.506
DOC_PP2B_LxvP_1	198	201	PF13499	0.453
DOC_PP2B_LxvP_1	409	412	PF13499	0.575
DOC_PP2B_PxIxI_1	849	855	PF00149	0.564
DOC_PP4_FxxP_1	461	464	PF00568	0.653
DOC_USP7_MATH_1	101	105	PF00917	0.513
DOC_USP7_MATH_1	174	178	PF00917	0.585
DOC_USP7_MATH_1	234	238	PF00917	0.451
DOC_USP7_MATH_1	452	456	PF00917	0.661
DOC_USP7_MATH_1	563	567	PF00917	0.499
DOC_USP7_MATH_1	618	622	PF00917	0.547
DOC_USP7_MATH_1	76	80	PF00917	0.543
DOC_USP7_MATH_1	770	774	PF00917	0.609
DOC_USP7_MATH_1	960	964	PF00917	0.382
DOC_WW_Pin1_4	1055	1060	PF00397	0.229
DOC_WW_Pin1_4	108	113	PF00397	0.438
DOC_WW_Pin1_4	26	31	PF00397	0.650
DOC_WW_Pin1_4	294	299	PF00397	0.516
DOC_WW_Pin1_4	335	340	PF00397	0.477
DOC_WW_Pin1_4	444	449	PF00397	0.723
DOC_WW_Pin1_4	470	475	PF00397	0.772
DOC_WW_Pin1_4	766	771	PF00397	0.788
DOC_WW_Pin1_4	817	822	PF00397	0.663
DOC_WW_Pin1_4	856	861	PF00397	0.557
DOC_WW_Pin1_4	965	970	PF00397	0.381
LIG_14-3-3_CanoR_1	1063	1072	PF00244	0.396
LIG_14-3-3_CanoR_1	1180	1186	PF00244	0.706
LIG_14-3-3_CanoR_1	164	170	PF00244	0.618
LIG_14-3-3_CanoR_1	454	464	PF00244	0.636
LIG_14-3-3_CanoR_1	543	550	PF00244	0.565
LIG_14-3-3_CanoR_1	561	570	PF00244	0.483
LIG_14-3-3_CanoR_1	605	610	PF00244	0.539
LIG_14-3-3_CanoR_1	633	639	PF00244	0.477
LIG_14-3-3_CanoR_1	726	734	PF00244	0.612
LIG_14-3-3_CanoR_1	837	845	PF00244	0.555
LIG_14-3-3_CanoR_1	865	870	PF00244	0.482
LIG_14-3-3_CanoR_1	910	917	PF00244	0.448
LIG_Actin_WH2_2	365	383	PF00022	0.513
LIG_AP2alpha_2	253	255	PF02296	0.448
LIG_APCC_ABBA_1	493	498	PF00400	0.452
LIG_BIR_III_4	648	652	PF00653	0.598
LIG_BRCT_BRCA1_1	1015	1019	PF00533	0.465
LIG_BRCT_BRCA1_1	694	698	PF00533	0.498
LIG_deltaCOP1_diTrp_1	78	83	PF00928	0.496
LIG_EH1_1	1107	1115	PF00400	0.256
LIG_EH1_1	373	381	PF00400	0.448
LIG_EVH1_2	466	470	PF00568	0.646
LIG_FHA_1	1008	1014	PF00498	0.513
LIG_FHA_1	1024	1030	PF00498	0.442
LIG_FHA_1	1047	1053	PF00498	0.270
LIG_FHA_1	1129	1135	PF00498	0.244
LIG_FHA_1	114	120	PF00498	0.440
LIG_FHA_1	1147	1153	PF00498	0.402
LIG_FHA_1	188	194	PF00498	0.673
LIG_FHA_1	348	354	PF00498	0.483
LIG_FHA_1	367	373	PF00498	0.608
LIG_FHA_1	404	410	PF00498	0.572
LIG_FHA_1	411	417	PF00498	0.587
LIG_FHA_1	423	429	PF00498	0.589
LIG_FHA_1	451	457	PF00498	0.683
LIG_FHA_1	483	489	PF00498	0.564
LIG_FHA_1	605	611	PF00498	0.503
LIG_FHA_1	755	761	PF00498	0.650
LIG_FHA_1	780	786	PF00498	0.627
LIG_FHA_1	840	846	PF00498	0.518
LIG_FHA_2	108	114	PF00498	0.491
LIG_FHA_2	1133	1139	PF00498	0.270
LIG_FHA_2	186	192	PF00498	0.718
LIG_FHA_2	439	445	PF00498	0.658
LIG_FHA_2	533	539	PF00498	0.522
LIG_FHA_2	857	863	PF00498	0.529
LIG_LIR_Apic_2	458	464	PF02991	0.638
LIG_LIR_Gen_1	1025	1035	PF02991	0.344
LIG_LIR_Gen_1	1138	1146	PF02991	0.336
LIG_LIR_Gen_1	151	159	PF02991	0.655
LIG_LIR_Gen_1	220	229	PF02991	0.469
LIG_LIR_Gen_1	321	330	PF02991	0.449
LIG_LIR_Gen_1	78	88	PF02991	0.509
LIG_LIR_Nem_3	1016	1021	PF02991	0.518
LIG_LIR_Nem_3	1138	1144	PF02991	0.317
LIG_LIR_Nem_3	151	156	PF02991	0.678
LIG_LIR_Nem_3	220	224	PF02991	0.452
LIG_LIR_Nem_3	321	325	PF02991	0.461
LIG_LIR_Nem_3	329	334	PF02991	0.491
LIG_LIR_Nem_3	78	84	PF02991	0.533
LIG_LIR_Nem_3	834	839	PF02991	0.578
LIG_NRBOX	865	871	PF00104	0.595
LIG_NRP_CendR_1	1191	1194	PF00754	0.447
LIG_Pex14_1	1079	1083	PF04695	0.367
LIG_Pex14_2	1019	1023	PF04695	0.376
LIG_Pex14_2	1097	1101	PF04695	0.451
LIG_Pex14_2	132	136	PF04695	0.267
LIG_PTB_Apo_2	915	922	PF02174	0.455
LIG_REV1ctd_RIR_1	1083	1093	PF16727	0.276
LIG_SH2_CRK	1038	1042	PF00017	0.251
LIG_SH2_CRK	1141	1145	PF00017	0.281
LIG_SH2_CRK	172	176	PF00017	0.534
LIG_SH2_GRB2like	609	612	PF00017	0.597
LIG_SH2_GRB2like	787	790	PF00017	0.655
LIG_SH2_SRC	787	790	PF00017	0.650
LIG_SH2_STAP1	1141	1145	PF00017	0.367
LIG_SH2_STAP1	1163	1167	PF00017	0.562
LIG_SH2_STAP1	22	26	PF00017	0.557
LIG_SH2_STAP1	341	345	PF00017	0.474
LIG_SH2_STAP1	374	378	PF00017	0.513
LIG_SH2_STAT3	147	150	PF00017	0.545
LIG_SH2_STAT3	848	851	PF00017	0.466
LIG_SH2_STAT5	1064	1067	PF00017	0.270
LIG_SH2_STAT5	333	336	PF00017	0.535
LIG_SH2_STAT5	609	612	PF00017	0.581
LIG_SH2_STAT5	634	637	PF00017	0.540
LIG_SH2_STAT5	848	851	PF00017	0.522
LIG_SH3_3	1048	1054	PF00018	0.228
LIG_SH3_3	1056	1062	PF00018	0.203
LIG_SH3_3	355	361	PF00018	0.499
LIG_SH3_3	459	465	PF00018	0.716
LIG_SH3_3	483	489	PF00018	0.564
LIG_SH3_3	612	618	PF00018	0.595
LIG_SH3_3	685	691	PF00018	0.564
LIG_SH3_3	734	740	PF00018	0.672
LIG_SH3_3	746	752	PF00018	0.671
LIG_SH3_3	966	972	PF00018	0.284
LIG_SH3_3	992	998	PF00018	0.524
LIG_SUMO_SIM_anti_2	268	274	PF11976	0.513
LIG_SUMO_SIM_anti_2	350	357	PF11976	0.484
LIG_SUMO_SIM_anti_2	912	919	PF11976	0.499
LIG_SUMO_SIM_par_1	1118	1123	PF11976	0.468
LIG_SUMO_SIM_par_1	356	362	PF11976	0.499
LIG_SUMO_SIM_par_1	364	369	PF11976	0.499
LIG_SUMO_SIM_par_1	703	708	PF11976	0.506
LIG_SUMO_SIM_par_1	912	919	PF11976	0.499
LIG_TRAF2_1	40	43	PF00917	0.625
LIG_TRAF2_2	821	826	PF00917	0.619
LIG_TYR_ITIM	1036	1041	PF00017	0.256
LIG_UBA3_1	1177	1186	PF00899	0.588
LIG_WRC_WIRS_1	137	142	PF05994	0.208
LIG_WRC_WIRS_1	319	324	PF05994	0.276
LIG_WRC_WIRS_1	439	444	PF05994	0.567
LIG_WRC_WIRS_1	539	544	PF05994	0.343
LIG_WRC_WIRS_1	954	959	PF05994	0.361
LIG_WW_2	737	740	PF00397	0.532
MOD_CDC14_SPxK_1	968	971	PF00782	0.326
MOD_CDK_SPK_2	1055	1060	PF00069	0.208
MOD_CDK_SPxK_1	965	971	PF00069	0.326
MOD_CDK_SPxxK_3	108	115	PF00069	0.452
MOD_CDK_SPxxK_3	470	477	PF00069	0.537
MOD_CDK_SPxxK_3	856	863	PF00069	0.416
MOD_CK1_1	1007	1013	PF00069	0.411
MOD_CK1_1	1055	1061	PF00069	0.287
MOD_CK1_1	1184	1190	PF00069	0.612
MOD_CK1_1	185	191	PF00069	0.565
MOD_CK1_1	237	243	PF00069	0.438
MOD_CK1_1	258	264	PF00069	0.324
MOD_CK1_1	288	294	PF00069	0.367
MOD_CK1_1	422	428	PF00069	0.602
MOD_CK1_1	455	461	PF00069	0.549
MOD_CK1_1	473	479	PF00069	0.653
MOD_CK1_1	532	538	PF00069	0.322
MOD_CK1_1	565	571	PF00069	0.371
MOD_CK1_1	753	759	PF00069	0.645
MOD_CK2_1	1132	1138	PF00069	0.377
MOD_CK2_1	37	43	PF00069	0.666
MOD_CK2_1	56	62	PF00069	0.345
MOD_CK2_1	766	772	PF00069	0.552
MOD_CK2_1	791	797	PF00069	0.569
MOD_CK2_1	83	89	PF00069	0.368
MOD_CK2_1	837	843	PF00069	0.519
MOD_Cter_Amidation	1191	1194	PF01082	0.705
MOD_GlcNHglycan	1043	1046	PF01048	0.394
MOD_GlcNHglycan	1054	1057	PF01048	0.266
MOD_GlcNHglycan	1146	1149	PF01048	0.291
MOD_GlcNHglycan	1186	1189	PF01048	0.640
MOD_GlcNHglycan	213	216	PF01048	0.376
MOD_GlcNHglycan	257	260	PF01048	0.284
MOD_GlcNHglycan	264	268	PF01048	0.326
MOD_GlcNHglycan	281	284	PF01048	0.224
MOD_GlcNHglycan	39	42	PF01048	0.595
MOD_GlcNHglycan	421	424	PF01048	0.555
MOD_GlcNHglycan	43	47	PF01048	0.519
MOD_GlcNHglycan	636	639	PF01048	0.514
MOD_GlcNHglycan	730	733	PF01048	0.691
MOD_GlcNHglycan	788	792	PF01048	0.795
MOD_GlcNHglycan	826	829	PF01048	0.663
MOD_GlcNHglycan	874	878	PF01048	0.303
MOD_GlcNHglycan	950	953	PF01048	0.451
MOD_GSK3_1	1128	1135	PF00069	0.291
MOD_GSK3_1	183	190	PF00069	0.682
MOD_GSK3_1	26	33	PF00069	0.645
MOD_GSK3_1	285	292	PF00069	0.333
MOD_GSK3_1	364	371	PF00069	0.277
MOD_GSK3_1	396	403	PF00069	0.419
MOD_GSK3_1	478	485	PF00069	0.587
MOD_GSK3_1	510	517	PF00069	0.486
MOD_GSK3_1	528	535	PF00069	0.347
MOD_GSK3_1	538	545	PF00069	0.451
MOD_GSK3_1	634	641	PF00069	0.377
MOD_GSK3_1	705	712	PF00069	0.374
MOD_GSK3_1	750	757	PF00069	0.597
MOD_GSK3_1	766	773	PF00069	0.551
MOD_GSK3_1	787	794	PF00069	0.560
MOD_GSK3_1	813	820	PF00069	0.473
MOD_GSK3_1	879	886	PF00069	0.340
MOD_GSK3_1	944	951	PF00069	0.275
MOD_N-GLC_1	347	352	PF02516	0.284
MOD_N-GLC_1	513	518	PF02516	0.344
MOD_N-GLC_1	742	747	PF02516	0.635
MOD_N-GLC_1	780	785	PF02516	0.741
MOD_N-GLC_1	817	822	PF02516	0.483
MOD_N-GLC_1	948	953	PF02516	0.414
MOD_N-GLC_1	965	970	PF02516	0.313
MOD_N-GLC_2	37	39	PF02516	0.507
MOD_NEK2_1	1023	1028	PF00069	0.337
MOD_NEK2_1	107	112	PF00069	0.493
MOD_NEK2_1	1144	1149	PF00069	0.405
MOD_NEK2_1	1181	1186	PF00069	0.481
MOD_NEK2_1	136	141	PF00069	0.436
MOD_NEK2_1	225	230	PF00069	0.450
MOD_NEK2_1	255	260	PF00069	0.308
MOD_NEK2_1	334	339	PF00069	0.337
MOD_NEK2_1	366	371	PF00069	0.366
MOD_NEK2_1	372	377	PF00069	0.326
MOD_NEK2_1	527	532	PF00069	0.377
MOD_NEK2_1	542	547	PF00069	0.300
MOD_NEK2_1	779	784	PF00069	0.532
MOD_NEK2_1	805	810	PF00069	0.624
MOD_NEK2_1	824	829	PF00069	0.576
MOD_NEK2_1	83	88	PF00069	0.449
MOD_NEK2_1	944	949	PF00069	0.340
MOD_NEK2_1	999	1004	PF00069	0.349
MOD_NEK2_2	452	457	PF00069	0.529
MOD_NEK2_2	742	747	PF00069	0.591
MOD_PIKK_1	532	538	PF00454	0.256
MOD_PIKK_1	542	548	PF00454	0.256
MOD_PIKK_1	692	698	PF00454	0.347
MOD_PIKK_1	70	76	PF00454	0.279
MOD_PKA_1	165	171	PF00069	0.464
MOD_PKA_1	909	915	PF00069	0.276
MOD_PKA_2	1161	1167	PF00069	0.541
MOD_PKA_2	1181	1187	PF00069	0.610
MOD_PKA_2	165	171	PF00069	0.441
MOD_PKA_2	510	516	PF00069	0.355
MOD_PKA_2	542	548	PF00069	0.357
MOD_PKA_2	604	610	PF00069	0.406
MOD_PKA_2	62	68	PF00069	0.268
MOD_PKA_2	632	638	PF00069	0.534
MOD_PKA_2	909	915	PF00069	0.276
MOD_Plk_1	234	240	PF00069	0.416
MOD_Plk_1	437	443	PF00069	0.502
MOD_Plk_1	709	715	PF00069	0.393
MOD_Plk_1	742	748	PF00069	0.554
MOD_Plk_1	780	786	PF00069	0.735
MOD_Plk_2-3	438	444	PF00069	0.684
MOD_Plk_4	101	107	PF00069	0.372
MOD_Plk_4	1013	1019	PF00069	0.333
MOD_Plk_4	1101	1107	PF00069	0.325
MOD_Plk_4	1139	1145	PF00069	0.419
MOD_Plk_4	131	137	PF00069	0.344
MOD_Plk_4	165	171	PF00069	0.378
MOD_Plk_4	258	264	PF00069	0.350
MOD_Plk_4	396	402	PF00069	0.373
MOD_Plk_4	430	436	PF00069	0.433
MOD_Plk_4	457	463	PF00069	0.497
MOD_Plk_4	605	611	PF00069	0.384
MOD_Plk_4	76	82	PF00069	0.358
MOD_Plk_4	780	786	PF00069	0.530
MOD_Plk_4	865	871	PF00069	0.338
MOD_Plk_4	925	931	PF00069	0.366
MOD_ProDKin_1	1055	1061	PF00069	0.249
MOD_ProDKin_1	108	114	PF00069	0.445
MOD_ProDKin_1	26	32	PF00069	0.569
MOD_ProDKin_1	294	300	PF00069	0.371
MOD_ProDKin_1	335	341	PF00069	0.316
MOD_ProDKin_1	444	450	PF00069	0.659
MOD_ProDKin_1	470	476	PF00069	0.724
MOD_ProDKin_1	766	772	PF00069	0.752
MOD_ProDKin_1	817	823	PF00069	0.575
MOD_ProDKin_1	856	862	PF00069	0.421
MOD_ProDKin_1	965	971	PF00069	0.368
MOD_SUMO_rev_2	1002	1010	PF00179	0.343
MOD_SUMO_rev_2	648	657	PF00179	0.365
MOD_SUMO_rev_2	8	17	PF00179	0.457
TRG_DiLeu_BaEn_1	268	273	PF01217	0.419
TRG_DiLeu_BaLyEn_6	1086	1091	PF01217	0.276
TRG_DiLeu_BaLyEn_6	1154	1159	PF01217	0.287
TRG_DiLeu_BaLyEn_6	862	867	PF01217	0.386
TRG_ENDOCYTIC_2	1038	1041	PF00928	0.414
TRG_ENDOCYTIC_2	1141	1144	PF00928	0.367
TRG_ENDOCYTIC_2	172	175	PF00928	0.404
TRG_ER_diArg_1	1179	1182	PF00400	0.529
TRG_ER_diArg_1	164	166	PF00400	0.482
TRG_ER_diArg_1	558	561	PF00400	0.412
TRG_ER_diArg_1	590	593	PF00400	0.343
TRG_ER_diArg_1	870	872	PF00400	0.369
TRG_NES_CRM1_1	347	362	PF08389	0.361
TRG_NES_CRM1_1	673	685	PF08389	0.328
TRG_Pf-PMV_PEXEL_1	1166	1171	PF00026	0.570
TRG_Pf-PMV_PEXEL_1	837	841	PF00026	0.424

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8I8	Leptomonas seymouri	67%	98%
A0A1X0P0Y8	Trypanosomatidae	47%	100%
A0A3S7WUG2	Leishmania donovani	35%	100%
A0A3S7X6H3	Leishmania donovani	95%	100%
A4HLF4	Leishmania braziliensis	80%	100%
A4HTF0	Leishmania infantum	32%	100%
A4HXD4	Leishmania infantum	35%	100%
A4I8W5	Leishmania infantum	95%	100%
E9AR29	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9B3T4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4QED4	Leishmania major	36%	100%
Q95Z93	Leishmania major	25%	100%
V5BPC6	Trypanosoma cruzi	48%	100%