LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q487_LEIMA
TriTrypDb:
LmjF.33.1035 , LMJLV39_330017700 * , LMJSD75_330017500
Length:
177

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 4
Forrest at al. (procyclic) no yes: 4
Silverman et al. no yes: 0
Pissara et al. no yes: 9
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q487
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q487

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 170 174 PF00656 0.665
CLV_C14_Caspase3-7 87 91 PF00656 0.794
CLV_PCSK_SKI1_1 39 43 PF00082 0.726
CLV_PCSK_SKI1_1 9 13 PF00082 0.722
DOC_PP4_FxxP_1 143 146 PF00568 0.445
DOC_PP4_FxxP_1 150 153 PF00568 0.422
DOC_USP7_MATH_1 17 21 PF00917 0.566
DOC_USP7_MATH_1 22 26 PF00917 0.702
DOC_USP7_MATH_1 5 9 PF00917 0.723
DOC_USP7_MATH_1 50 54 PF00917 0.670
DOC_USP7_MATH_1 78 82 PF00917 0.760
DOC_WW_Pin1_4 128 133 PF00397 0.499
DOC_WW_Pin1_4 61 66 PF00397 0.628
LIG_BRCT_BRCA1_1 146 150 PF00533 0.488
LIG_FHA_2 85 91 PF00498 0.798
LIG_LIR_Apic_2 139 145 PF02991 0.426
LIG_LIR_Apic_2 147 153 PF02991 0.438
LIG_LIR_Apic_2 156 161 PF02991 0.437
LIG_PDZ_Class_3 172 177 PF00595 0.700
LIG_SH2_STAT5 135 138 PF00017 0.539
LIG_SH2_STAT5 142 145 PF00017 0.434
LIG_SH3_3 115 121 PF00018 0.631
LIG_SH3_3 67 73 PF00018 0.659
MOD_CK1_1 20 26 PF00069 0.781
MOD_CK1_1 66 72 PF00069 0.687
MOD_CK2_1 169 175 PF00069 0.643
MOD_GlcNHglycan 107 110 PF01048 0.666
MOD_GlcNHglycan 13 16 PF01048 0.624
MOD_GlcNHglycan 20 23 PF01048 0.540
MOD_GlcNHglycan 3 6 PF01048 0.725
MOD_GlcNHglycan 59 62 PF01048 0.706
MOD_GSK3_1 1 8 PF00069 0.721
MOD_GSK3_1 18 25 PF00069 0.489
MOD_GSK3_1 46 53 PF00069 0.755
MOD_GSK3_1 57 64 PF00069 0.609
MOD_GSK3_1 84 91 PF00069 0.757
MOD_N-GLC_1 32 37 PF02516 0.621
MOD_N-GLC_1 54 59 PF02516 0.673
MOD_N-GLC_1 61 66 PF02516 0.634
MOD_NEK2_1 1 6 PF00069 0.702
MOD_NMyristoyl 1 7 PF02799 0.651
MOD_PIKK_1 50 56 PF00454 0.666
MOD_Plk_1 66 72 PF00069 0.647
MOD_Plk_2-3 169 175 PF00069 0.670
MOD_ProDKin_1 128 134 PF00069 0.490
MOD_ProDKin_1 61 67 PF00069 0.627
MOD_SPalmitoyl_4 1 7 PF01529 0.651
MOD_SUMO_for_1 126 129 PF00179 0.553
MOD_SUMO_rev_2 4 14 PF00179 0.643
MOD_SUMO_rev_2 79 87 PF00179 0.792

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I074 Leptomonas seymouri 55% 100%
A0A3S7X6J5 Leishmania donovani 84% 100%
A4I8W8 Leishmania infantum 84% 100%
D0A4W3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 100%
E9B3T7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 71% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS