Peptidyl-prolyl cis-trans isomerase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cyclophilin 4, putative

Species:

Leishmania major

UniProt:

Q4Q424_LEIMA

TriTrypDb:

LmjF.33.1630 , LMJLV39_330025100 , LMJSD75_330024800

Length:

220

Annotations

LeishMANIAdb annotations

A large collection of conserved eukaryotic peptidyl-prolyl cis-trans isomerases. Some members of this group are secreted (into the ER).. Localization: Cytoplasmic (by homology) / ER (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 1
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 30

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	4
GO:0016020	membrane	2	2

Expansion

Sequence features

Q4Q424

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q424

PDB structure(s): 2hqj_A

Function

Biological processes
Term	Name	Level	Count
GO:0000413	protein peptidyl-prolyl isomerization	7	13
GO:0006457	protein folding	2	13
GO:0006807	nitrogen compound metabolic process	2	13
GO:0008152	metabolic process	1	13
GO:0009987	cellular process	1	13
GO:0018193	peptidyl-amino acid modification	5	13
GO:0018208	peptidyl-proline modification	6	13
GO:0019538	protein metabolic process	3	13
GO:0036211	protein modification process	4	13
GO:0043170	macromolecule metabolic process	3	13
GO:0043412	macromolecule modification	4	13
GO:0044238	primary metabolic process	2	13
GO:0071704	organic substance metabolic process	2	13
GO:1901564	organonitrogen compound metabolic process	3	13

Molecular functions
Term	Name	Level	Count
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3	13
GO:0003824	catalytic activity	1	13
GO:0005488	binding	1	2
GO:0016018	cyclosporin A binding	4	2
GO:0016853	isomerase activity	2	13
GO:0016859	cis-trans isomerase activity	3	13
GO:0033218	amide binding	2	2
GO:0042277	peptide binding	3	2
GO:0140096	catalytic activity, acting on a protein	2	13

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	173	177	PF00656	0.354
CLV_NRD_NRD_1	27	29	PF00675	0.548
CLV_NRD_NRD_1	35	37	PF00675	0.397
CLV_PCSK_KEX2_1	27	29	PF00082	0.673
CLV_PCSK_KEX2_1	35	37	PF00082	0.508
CLV_PCSK_SKI1_1	28	32	PF00082	0.537
DOC_ANK_TNKS_1	143	150	PF00023	0.411
DOC_MAPK_MEF2A_6	13	21	PF00069	0.442
DOC_PP1_RVXF_1	176	183	PF00149	0.338
DOC_PP1_RVXF_1	92	99	PF00149	0.380
DOC_USP7_MATH_1	134	138	PF00917	0.318
DOC_USP7_MATH_1	41	45	PF00917	0.424
LIG_14-3-3_CanoR_1	13	18	PF00244	0.619
LIG_14-3-3_CanoR_1	206	212	PF00244	0.458
LIG_14-3-3_CanoR_1	27	31	PF00244	0.476
LIG_Actin_WH2_2	5	20	PF00022	0.407
LIG_APCC_ABBA_1	65	70	PF00400	0.338
LIG_BRCT_BRCA1_1	162	166	PF00533	0.338
LIG_DLG_GKlike_1	13	21	PF00625	0.386
LIG_FHA_1	170	176	PF00498	0.338
LIG_FHA_2	121	127	PF00498	0.287
LIG_FHA_2	208	214	PF00498	0.303
LIG_LIR_Gen_1	101	111	PF02991	0.310
LIG_LIR_Gen_1	186	195	PF02991	0.336
LIG_LIR_Nem_3	101	106	PF02991	0.310
LIG_LIR_Nem_3	186	192	PF02991	0.336
LIG_LIR_Nem_3	66	71	PF02991	0.308
LIG_LIR_Nem_3	77	82	PF02991	0.350
LIG_MLH1_MIPbox_1	162	166	PF16413	0.338
LIG_SH2_CRK	189	193	PF00017	0.401
LIG_SH2_STAP1	189	193	PF00017	0.411
LIG_SH2_STAT5	10	13	PF00017	0.449
LIG_SH3_1	35	41	PF00018	0.393
LIG_SH3_3	16	22	PF00018	0.563
LIG_SH3_3	35	41	PF00018	0.424
LIG_SUMO_SIM_par_1	207	213	PF11976	0.300
MOD_CK1_1	202	208	PF00069	0.370
MOD_CK1_1	54	60	PF00069	0.346
MOD_CK2_1	120	126	PF00069	0.287
MOD_GlcNHglycan	201	204	PF01048	0.354
MOD_GlcNHglycan	31	34	PF01048	0.503
MOD_GlcNHglycan	91	94	PF01048	0.305
MOD_GSK3_1	120	127	PF00069	0.341
MOD_GSK3_1	13	20	PF00069	0.415
MOD_N-GLC_1	120	125	PF02516	0.338
MOD_N-GLC_1	160	165	PF02516	0.329
MOD_NEK2_1	166	171	PF00069	0.338
MOD_NEK2_1	17	22	PF00069	0.514
MOD_NEK2_1	26	31	PF00069	0.517
MOD_NEK2_1	51	56	PF00069	0.287
MOD_NEK2_1	6	11	PF00069	0.411
MOD_NEK2_1	98	103	PF00069	0.374
MOD_NEK2_2	124	129	PF00069	0.338
MOD_PIKK_1	160	166	PF00454	0.338
MOD_PIKK_1	194	200	PF00454	0.390
MOD_PIKK_1	54	60	PF00454	0.321
MOD_PKA_2	26	32	PF00069	0.518
MOD_Plk_1	134	140	PF00069	0.338
MOD_Plk_1	51	57	PF00069	0.287
MOD_Plk_4	124	130	PF00069	0.338
MOD_SUMO_for_1	193	196	PF00179	0.291
MOD_SUMO_for_1	217	220	PF00179	0.610
MOD_SUMO_rev_2	173	180	PF00179	0.359
TRG_ENDOCYTIC_2	189	192	PF00928	0.338
TRG_ER_diArg_1	26	28	PF00400	0.679
TRG_ER_diArg_1	35	37	PF00400	0.501
TRG_Pf-PMV_PEXEL_1	105	109	PF00026	0.338

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A075B759	Homo sapiens	56%	100%
A0A075B767	Homo sapiens	56%	100%
A0A0B4J2A2	Homo sapiens	57%	100%
A0A0N0P364	Leptomonas seymouri	49%	96%
A0A0N0P3D1	Leptomonas seymouri	30%	100%
A0A0N0P523	Leptomonas seymouri	67%	80%
A0A0N0P839	Leptomonas seymouri	90%	100%
A0A0N1I0P5	Leptomonas seymouri	70%	100%
A0A0N1I6E6	Leptomonas seymouri	56%	100%
A0A0N1I8P9	Leptomonas seymouri	53%	75%
A0A0N1IL84	Leptomonas seymouri	34%	69%
A0A0N1PC19	Leptomonas seymouri	36%	100%
A0A0N1PDY0	Leptomonas seymouri	32%	90%
A0A0S4IKA5	Bodo saltans	36%	72%
A0A0S4IZ55	Bodo saltans	25%	100%
A0A0S4J0W0	Bodo saltans	63%	90%
A0A0S4J378	Bodo saltans	56%	100%
A0A0S4J465	Bodo saltans	26%	91%
A0A0S4J4A4	Bodo saltans	64%	100%
A0A0S4J7K8	Bodo saltans	68%	100%
A0A0S4J8W7	Bodo saltans	48%	95%
A0A0S4J9U9	Bodo saltans	34%	100%
A0A0S4JID7	Bodo saltans	61%	98%
A0A0S4KGS8	Bodo saltans	38%	89%
A0A0S4KLH0	Bodo saltans	83%	100%
A0A1X0NJS0	Trypanosomatidae	56%	100%
A0A1X0NTQ9	Trypanosomatidae	56%	96%
A0A1X0NTS4	Trypanosomatidae	52%	95%
A0A1X0NXG7	Trypanosomatidae	68%	85%
A0A1X0P184	Trypanosomatidae	87%	100%
A0A1X0P2K2	Trypanosomatidae	36%	84%
A0A1X0P4X3	Trypanosomatidae	38%	100%
A0A1X0P5F9	Trypanosomatidae	69%	100%
A0A3Q8ICB3	Leishmania donovani	46%	96%
A0A3Q8IDR1	Leishmania donovani	39%	77%
A0A3R7M7E5	Trypanosoma rangeli	36%	71%
A0A3R7MER6	Trypanosoma rangeli	42%	66%
A0A3R7MP70	Trypanosoma rangeli	41%	100%
A0A3R7NMR3	Trypanosoma rangeli	69%	100%
A0A3R7RC31	Trypanosoma rangeli	84%	100%
A0A3R7RE54	Trypanosoma rangeli	66%	86%
A0A3R7RI88	Trypanosoma rangeli	54%	100%
A0A3S5H5N2	Leishmania donovani	55%	100%
A0A3S5H7U6	Leishmania donovani	98%	85%
A0A3S5IQL2	Trypanosoma rangeli	36%	85%
A0A3S7WXF4	Leishmania donovani	66%	74%
A0A3S7WYD9	Leishmania donovani	26%	91%
A0A3S7WYY5	Leishmania donovani	71%	100%
A0A3S7X325	Leishmania donovani	33%	90%
A0A3S7X410	Leishmania donovani	55%	96%
A0A3S7XB52	Leishmania donovani	37%	83%
A0A422N1Z9	Trypanosoma rangeli	56%	98%
A0A422N490	Trypanosoma rangeli	47%	95%
A4FV72	Bos taurus	63%	73%
A4H4H8	Leishmania braziliensis	53%	100%
A4HCI8	Leishmania braziliensis	47%	96%
A4HCL8	Leishmania braziliensis	66%	74%
A4HE26	Leishmania braziliensis	72%	100%
A4HHU7	Leishmania braziliensis	33%	90%
A4HIW9	Leishmania braziliensis	54%	96%
A4HLM4	Leishmania braziliensis	92%	100%
A4HPH9	Leishmania braziliensis	37%	100%
A4HSQ3	Leishmania infantum	55%	100%
A4I004	Leishmania infantum	46%	96%
A4I042	Leishmania infantum	66%	74%
A4I0X0	Leishmania infantum	26%	91%
A4I1D2	Leishmania infantum	71%	100%
A4I4Z7	Leishmania infantum	33%	90%
A4I698	Leishmania infantum	55%	96%
A4I935	Leishmania infantum	98%	85%
A4IDA1	Leishmania infantum	37%	83%
A8X8D0	Caenorhabditis briggsae	49%	70%
B3A0R0	Lottia gigantea	52%	100%
C9ZIV0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	86%	100%
C9ZNS2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	93%
C9ZQE6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	85%
C9ZRQ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	98%
C9ZSQ5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	95%
C9ZT99	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	100%
C9ZUX8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	64%	73%
C9ZVY5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	78%
C9ZWH7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
D0A5M6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	100%
D0A8E1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
D4AY02	Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)	57%	97%
E9AFI5	Leishmania major	30%	89%
E9AKP0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	100%
E9AT91	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9AVX7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	48%	96%
E9AW05	Leishmania mexicana (strain MHOM/GT/2001/U1103)	68%	76%
E9AWX4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	91%
E9AXG9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	69%	100%
E9B0C7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	90%
E9B1F3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	54%	96%
E9B400	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	86%
F5H284	Homo sapiens	56%	100%
O00060	Uromyces fabae	58%	100%
O00845	Paramecium primaurelia	53%	100%
O02614	Leishmania major	69%	98%
O43447	Homo sapiens	55%	100%
O49605	Arabidopsis thaliana	50%	98%
O49886	Lupinus luteus	69%	100%
O53021	Dickeya dadantii (strain 3937)	31%	100%
O74729	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	50%	100%
O93826	Arthroderma benhamiae	57%	97%
O94273	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	53%	100%
P0C1H7	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	63%	100%
P0C1H8	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	64%	100%
P0C1H9	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	47%	100%
P0C1I0	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	47%	100%
P0C1I2	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	64%	70%
P0C1I3	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	53%	100%
P0C1I4	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	49%	100%
P0C1I7	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	63%	100%
P0C1I8	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	62%	100%
P0CP78	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	54%	95%
P0CP79	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	54%	95%
P0CP82	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	56%	100%
P0CP83	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	56%	100%
P0CP84	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	49%	100%
P0CP85	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	49%	100%
P0DN26	Homo sapiens	56%	100%
P0DN37	Homo sapiens	56%	100%
P10111	Rattus norvegicus	64%	100%
P10255	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	50%	99%
P14088	Echinococcus granulosus	65%	100%
P14832	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	65%	100%
P14851	Cricetulus griseus	65%	100%
P15425	Drosophila melanogaster	43%	93%
P17742	Mus musculus	64%	100%
P18253	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	67%	100%
P21568	Solanum lycopersicum	72%	100%
P21569	Zea mays	69%	100%
P22011	Candida albicans (strain SC5314 / ATCC MYA-2876)	63%	100%
P23284	Homo sapiens	55%	100%
P23285	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	50%	100%
P23869	Escherichia coli (strain K12)	28%	100%
P24367	Gallus gallus	58%	100%
P24368	Rattus norvegicus	56%	100%
P24369	Mus musculus	55%	100%
P24525	Brassica napus	67%	100%
P25007	Drosophila melanogaster	64%	97%
P25334	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	69%
P25719	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	58%	100%
P28517	Calliphora vicina	39%	94%
P29117	Rattus norvegicus	65%	100%
P30404	Bos taurus	66%	100%
P30405	Homo sapiens	65%	100%
P30412	Mus musculus	57%	100%
P34790	Arabidopsis thaliana	70%	100%
P34791	Arabidopsis thaliana	54%	85%
P34887	Allium cepa	72%	100%
P35176	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	47%	98%
P35627	Unspecified eudicot DB-1992	63%	100%
P42693	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	32%	100%
P44499	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	28%	100%
P45877	Homo sapiens	58%	100%
P52009	Caenorhabditis elegans	71%	100%
P52010	Caenorhabditis elegans	66%	100%
P52011	Caenorhabditis elegans	69%	100%
P52013	Caenorhabditis elegans	52%	100%
P52014	Caenorhabditis elegans	50%	100%
P52015	Caenorhabditis elegans	69%	100%
P52018	Caenorhabditis elegans	52%	100%
P53728	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	71%
P54985	Blattella germanica	67%	100%
P62935	Bos taurus	65%	100%
P62936	Sus scrofa	65%	100%
P62937	Homo sapiens	64%	100%
P62938	Chlorocebus aethiops	64%	100%
P62940	Macaca mulatta	64%	100%
P62941	Papio anubis	64%	100%
P65763	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	38%	100%
P73789	Synechocystis sp. (strain PCC 6803 / Kazusa)	69%	100%
P80311	Bos taurus	56%	100%
P83221	Streptomyces antibioticus	32%	100%
P84343	Neospora caninum	50%	100%
P91791	Hemicentrotus pulcherrimus	66%	100%
P9WHW0	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	31%	71%
P9WHW1	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	31%	71%
P9WHW2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	38%	100%
P9WHW3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	38%	100%
Q01490	Orpinomyces sp. (strain PC-2)	56%	100%
Q06118	Streptomyces anulatus	58%	100%
Q08E11	Bos taurus	58%	100%
Q09637	Caenorhabditis elegans	47%	71%
Q0P5D0	Bos taurus	55%	100%
Q0ZQK3	Saguinus oedipus	63%	100%
Q0ZQK6	Symphalangus syndactylus	64%	100%
Q0ZQK7	Nomascus leucogenys	64%	100%
Q0ZQK8	Hylobates lar	64%	100%
Q0ZQL0	Gorilla gorilla gorilla	64%	100%
Q0ZQL1	Pan troglodytes	64%	100%
Q0ZQL2	Pan paniscus	64%	100%
Q1RMP7	Bos taurus	42%	72%
Q26516	Schistosoma japonicum	61%	100%
Q26548	Schistosoma mansoni	62%	81%
Q26551	Schistosoma mansoni	51%	100%
Q26565	Schistosoma mansoni	57%	100%
Q27774	Schistosoma japonicum	52%	100%
Q2FIC1	Staphylococcus aureus (strain USA300)	42%	100%
Q2FZU9	Staphylococcus aureus (strain NCTC 8325 / PS 47)	42%	100%
Q2TZ33	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	52%	100%
Q2U6U0	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	49%	100%
Q2UGK2	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	51%	100%
Q2YPY5	Brucella abortus (strain 2308)	34%	100%
Q2YWT2	Staphylococcus aureus (strain bovine RF122 / ET3-1)	42%	100%
Q38867	Arabidopsis thaliana	66%	100%
Q38900	Arabidopsis thaliana	66%	100%
Q39613	Catharanthus roseus	72%	100%
Q41651	Vicia faba	57%	89%
Q42406	Arabidopsis thaliana	69%	100%
Q49W93	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	42%	100%
Q4G338	Haemonchus contortus	58%	68%
Q4I5R9	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	56%	89%
Q4IPB8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	40%	100%
Q4IPH4	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	57%	100%
Q4L4W9	Staphylococcus haemolyticus (strain JCSC1435)	39%	100%
Q4P6X6	Ustilago maydis (strain 521 / FGSC 9021)	52%	100%
Q4Q1A6	Leishmania major	37%	100%
Q4Q6Q9	Leishmania major	55%	96%
Q4Q7V7	Leishmania major	33%	90%
Q4QAK0	Leishmania major	28%	91%
Q4QBH1	Leishmania major	68%	75%
Q4QBK2	Leishmania major	46%	96%
Q4QJ67	Leishmania major	54%	100%
Q4WCM6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	54%	100%
Q4WCR3	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	50%	100%
Q4WMB6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	34%	100%
Q4WP12	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	55%	100%
Q54SM3	Dictyostelium discoideum	70%	100%
Q57D43	Brucella abortus biovar 1 (strain 9-941)	34%	100%
Q5AQL0	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	54%	100%
Q5ASQ0	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	48%	100%
Q5B4R3	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	54%	100%
Q5BAH7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	36%	100%
Q5E992	Bos taurus	44%	100%
Q5HHD1	Staphylococcus aureus (strain COL)	42%	100%
Q5HQK8	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	40%	100%
Q5R723	Pongo abelii	63%	73%
Q5R8S7	Pongo pygmaeus	64%	100%
Q5UP71	Acanthamoeba polyphaga mimivirus	28%	94%
Q6C4W6	Yarrowia lipolytica (strain CLIB 122 / E 150)	58%	96%
Q6DTV9	Aotus trivirgatus	63%	100%
Q6GAX2	Staphylococcus aureus (strain MSSA476)	42%	100%
Q6GID4	Staphylococcus aureus (strain MRSA252)	42%	100%
Q6MWS8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	40%	100%
Q7A1C0	Staphylococcus aureus (strain MW2)	42%	100%
Q7A6I1	Staphylococcus aureus (strain N315)	42%	100%
Q7S7Z6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	58%	77%
Q7SG06	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	57%	100%
Q8CT84	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	40%	100%
Q8G0J9	Brucella suis biovar 1 (strain 1330)	35%	100%
Q8HXS3	Felis catus	65%	100%
Q8IXY8	Homo sapiens	43%	71%
Q8L8W5	Arabidopsis thaliana	62%	96%
Q8LDP4	Arabidopsis thaliana	63%	100%
Q8SRE1	Encephalitozoon cuniculi (strain GB-M1)	54%	100%
Q8W171	Glycine max	71%	100%
Q8X166	Aspergillus niger	55%	100%
Q8X191	Aspergillus niger	48%	100%
Q8YHB5	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	35%	100%
Q99KR7	Mus musculus	65%	100%
Q99VD4	Staphylococcus aureus (strain Mu50 / ATCC 700699)	42%	100%
Q9ASS6	Arabidopsis thaliana	57%	85%
Q9C835	Arabidopsis thaliana	28%	93%
Q9CDE9	Mycobacterium leprae (strain TN)	39%	100%
Q9D0W5	Mus musculus	45%	100%
Q9D6D8	Mus musculus	39%	70%
Q9D868	Mus musculus	60%	100%
Q9LIK6	Arabidopsis thaliana	41%	95%
Q9LPC7	Arabidopsis thaliana	46%	100%
Q9QZH3	Mus musculus	63%	73%
Q9SKQ0	Arabidopsis thaliana	71%	100%
Q9SP02	Arabidopsis thaliana	62%	100%
Q9TTC6	Oryctolagus cuniculus	63%	100%
Q9TW32	Dictyostelium discoideum	62%	100%
Q9UA41	Dictyostelium discoideum	59%	100%
Q9UNP9	Homo sapiens	61%	73%
Q9V3G3	Drosophila melanogaster	62%	73%
Q9Y3C6	Homo sapiens	44%	100%
Q9Y536	Homo sapiens	56%	100%
Q9ZVJ4	Arabidopsis thaliana	55%	100%
V5B2A0	Trypanosoma cruzi	67%	85%
V5B9Y6	Trypanosoma cruzi	38%	71%
V5BGX2	Trypanosoma cruzi	38%	83%
V5BHF5	Trypanosoma cruzi	85%	100%
V5BM49	Trypanosoma cruzi	36%	89%
V5D532	Trypanosoma cruzi	53%	100%
V5DJ29	Trypanosoma cruzi	40%	68%