LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q407_LEIMA
TriTrypDb:
LmjF.33.1810 , LMJLV39_330027400 , LMJSD75_330027000
Length:
388

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 15
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q407
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q407

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 2
GO:0016874 ligase activity 2 2
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 347 351 PF00656 0.331
CLV_NRD_NRD_1 115 117 PF00675 0.397
CLV_NRD_NRD_1 119 121 PF00675 0.394
CLV_NRD_NRD_1 354 356 PF00675 0.411
CLV_PCSK_KEX2_1 115 117 PF00082 0.454
CLV_PCSK_SKI1_1 116 120 PF00082 0.395
CLV_PCSK_SKI1_1 3 7 PF00082 0.465
DEG_APCC_KENBOX_2 207 211 PF00400 0.519
DOC_CYCLIN_yClb5_NLxxxL_5 162 171 PF00134 0.399
DOC_MAPK_FxFP_2 122 125 PF00069 0.453
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IM57 Leptomonas seymouri 67% 95%
A0A0S4JGX9 Bodo saltans 38% 100%
A0A1X0P3L5 Trypanosomatidae 48% 100%
A0A3Q8IME8 Leishmania donovani 95% 100%
A0A422N3E6 Trypanosoma rangeli 49% 97%
A4HLP1 Leishmania braziliensis 85% 100%
A4I976 Leishmania infantum 95% 100%
D0A6D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 47% 99%
E9B417 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
V5BTX0 Trypanosoma cruzi 47% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS