Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q403_LEIMA

TriTrypDb:

LmjF.33.1850 , LMJLV39_330028000 , LMJSD75_330027600

Length:

256

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q403

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q403

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	124	128	PF00656	0.620
CLV_C14_Caspase3-7	189	193	PF00656	0.436
CLV_NRD_NRD_1	32	34	PF00675	0.423
CLV_PCSK_KEX2_1	32	34	PF00082	0.421
CLV_PCSK_SKI1_1	226	230	PF00082	0.527
CLV_PCSK_SKI1_1	32	36	PF00082	0.429
CLV_PCSK_SKI1_1	9	13	PF00082	0.477
DOC_CYCLIN_yCln2_LP_2	138	144	PF00134	0.424
DOC_MAPK_gen_1	195	202	PF00069	0.518
DOC_MAPK_MEF2A_6	231	239	PF00069	0.405
DOC_PP2B_LxvP_1	138	141	PF13499	0.415
DOC_PP4_FxxP_1	145	148	PF00568	0.429
DOC_PP4_FxxP_1	88	91	PF00568	0.517
DOC_USP7_MATH_1	97	101	PF00917	0.764
DOC_WW_Pin1_4	144	149	PF00397	0.415
DOC_WW_Pin1_4	173	178	PF00397	0.586
DOC_WW_Pin1_4	73	78	PF00397	0.670
DOC_WW_Pin1_4	79	84	PF00397	0.609
LIG_APCC_ABBA_1	200	205	PF00400	0.438
LIG_BIR_II_1	1	5	PF00653	0.502
LIG_eIF4E_1	210	216	PF01652	0.451
LIG_FHA_1	173	179	PF00498	0.599
LIG_FHA_1	180	186	PF00498	0.443
LIG_FHA_2	236	242	PF00498	0.402
LIG_LIR_Apic_2	143	148	PF02991	0.426
LIG_LIR_Apic_2	87	91	PF02991	0.519
LIG_LIR_Gen_1	155	164	PF02991	0.464
LIG_LIR_Nem_3	155	161	PF02991	0.447
LIG_PTB_Apo_2	35	42	PF02174	0.424
LIG_PTB_Phospho_1	35	41	PF10480	0.394
LIG_SH2_CRK	52	56	PF00017	0.387
LIG_SH3_3	102	108	PF00018	0.709
LIG_SH3_3	16	22	PF00018	0.421
LIG_SUMO_SIM_anti_2	184	189	PF11976	0.497
LIG_SUMO_SIM_par_1	181	186	PF11976	0.515
LIG_TRAF2_1	238	241	PF00917	0.504
LIG_UBA3_1	130	139	PF00899	0.434
LIG_WRC_WIRS_1	248	253	PF05994	0.526
MOD_CDC14_SPxK_1	147	150	PF00782	0.416
MOD_CDC14_SPxK_1	82	85	PF00782	0.525
MOD_CDK_SPxK_1	144	150	PF00069	0.410
MOD_CDK_SPxK_1	79	85	PF00069	0.543
MOD_CK1_1	100	106	PF00069	0.594
MOD_CK1_1	201	207	PF00069	0.540
MOD_CK1_1	217	223	PF00069	0.354
MOD_CK1_1	247	253	PF00069	0.474
MOD_CK1_1	89	95	PF00069	0.590
MOD_CK2_1	235	241	PF00069	0.495
MOD_GlcNHglycan	1	4	PF01048	0.491
MOD_GlcNHglycan	164	168	PF01048	0.592
MOD_GlcNHglycan	61	64	PF01048	0.598
MOD_GlcNHglycan	67	70	PF01048	0.594
MOD_GlcNHglycan	92	95	PF01048	0.677
MOD_GSK3_1	140	147	PF00069	0.423
MOD_GSK3_1	152	159	PF00069	0.422
MOD_GSK3_1	172	179	PF00069	0.454
MOD_GSK3_1	214	221	PF00069	0.478
MOD_GSK3_1	73	80	PF00069	0.624
MOD_GSK3_1	86	93	PF00069	0.615
MOD_N-GLC_1	172	177	PF02516	0.666
MOD_N-GLC_1	241	246	PF02516	0.543
MOD_NEK2_1	156	161	PF00069	0.522
MOD_NEK2_1	183	188	PF00069	0.401
MOD_NEK2_2	198	203	PF00069	0.415
MOD_PKA_2	100	106	PF00069	0.609
MOD_PKA_2	41	47	PF00069	0.428
MOD_Plk_1	217	223	PF00069	0.524
MOD_Plk_1	26	32	PF00069	0.397
MOD_Plk_1	86	92	PF00069	0.536
MOD_Plk_2-3	111	117	PF00069	0.660
MOD_Plk_4	152	158	PF00069	0.418
MOD_Plk_4	183	189	PF00069	0.409
MOD_Plk_4	198	204	PF00069	0.464
MOD_Plk_4	244	250	PF00069	0.488
MOD_ProDKin_1	144	150	PF00069	0.410
MOD_ProDKin_1	173	179	PF00069	0.582
MOD_ProDKin_1	73	79	PF00069	0.671
MOD_SUMO_for_1	24	27	PF00179	0.430
TRG_DiLeu_BaLyEn_6	129	134	PF01217	0.434
TRG_ENDOCYTIC_2	157	160	PF00928	0.443
TRG_ENDOCYTIC_2	52	55	PF00928	0.382
TRG_ER_diArg_1	31	33	PF00400	0.433
TRG_Pf-PMV_PEXEL_1	132	136	PF00026	0.429

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P841	Leptomonas seymouri	59%	100%
A0A3S7X6W7	Leishmania donovani	91%	100%
A4HLP6	Leishmania braziliensis	75%	100%
A4I947	Leishmania infantum	91%	100%
E9B421	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%