Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Phosphate transport (Pho88), putative

Species:

Leishmania major

UniProt:

Q4Q3Z5_LEIMA

TriTrypDb:

LmjF.33.1920 , LMJLV39_330028900 , LMJSD75_330028500

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005783	endoplasmic reticulum	5	11
GO:0016020	membrane	2	10
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11

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Expansion

Sequence features

Q4Q3Z5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3Z5

Function

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Biological processes
Term	Name	Level	Count
GO:0006605	protein targeting	5	11
GO:0006810	transport	3	11
GO:0006886	intracellular protein transport	4	11
GO:0008104	protein localization	4	11
GO:0009987	cellular process	1	11
GO:0015031	protein transport	4	11
GO:0033036	macromolecule localization	2	11
GO:0033365	protein localization to organelle	5	11
GO:0045047	protein targeting to ER	6	11
GO:0045184	establishment of protein localization	3	11

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	185	187	PF00675	0.693
CLV_NRD_NRD_1	25	27	PF00675	0.422
CLV_PCSK_KEX2_1	131	133	PF00082	0.548
CLV_PCSK_KEX2_1	187	189	PF00082	0.731
CLV_PCSK_KEX2_1	25	27	PF00082	0.546
CLV_PCSK_PC1ET2_1	131	133	PF00082	0.497
CLV_PCSK_PC1ET2_1	187	189	PF00082	0.731
CLV_PCSK_PC7_1	127	133	PF00082	0.497
CLV_PCSK_SKI1_1	25	29	PF00082	0.546
DEG_Nend_UBRbox_3	1	3	PF02207	0.306

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDP6	Leptomonas seymouri	63%	100%
A0A0S4IMC9	Bodo saltans	35%	94%
A0A3S7X6X6	Leishmania donovani	93%	100%
A0A422N623	Trypanosoma rangeli	36%	100%
A4HJX0	Leishmania braziliensis	69%	99%
A4HLQ4	Leishmania braziliensis	70%	100%
A4I954	Leishmania infantum	92%	100%
D0A6C0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
E9B429	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%

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