Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q3Y5_LEIMA

TriTrypDb:

LmjF.33.2020 , LMJLV39_330030300 , LMJSD75_330029800

Length:

877

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

Q4Q3Y5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3Y5

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	100	102	PF00675	0.439
CLV_NRD_NRD_1	281	283	PF00675	0.492
CLV_NRD_NRD_1	294	296	PF00675	0.492
CLV_NRD_NRD_1	383	385	PF00675	0.584
CLV_NRD_NRD_1	386	388	PF00675	0.577
CLV_NRD_NRD_1	483	485	PF00675	0.529
CLV_NRD_NRD_1	575	577	PF00675	0.804
CLV_NRD_NRD_1	632	634	PF00675	0.470
CLV_NRD_NRD_1	672	674	PF00675	0.412
CLV_NRD_NRD_1	868	870	PF00675	0.465

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H7U8	Leishmania donovani	83%	100%
A4HLR4	Leishmania braziliensis	51%	100%
A4I964	Leishmania infantum	83%	100%
E9B440	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%

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