Kinesin motor domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q3W0_LEIMA

TriTrypDb:

LmjF.33.2270 , LMJLV39_330033200 , LMJLV39_330033300 , LMJSD75_330032800

Length:

579

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q3W0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3W0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	23	27	PF00656	0.598
CLV_C14_Caspase3-7	51	55	PF00656	0.566
CLV_NRD_NRD_1	532	534	PF00675	0.481
CLV_PCSK_SKI1_1	110	114	PF00082	0.636
CLV_PCSK_SKI1_1	515	519	PF00082	0.582
CLV_PCSK_SKI1_1	59	63	PF00082	0.557
CLV_PCSK_SKI1_1	87	91	PF00082	0.471
DEG_APCC_DBOX_1	100	108	PF00400	0.516
DEG_SPOP_SBC_1	45	49	PF00917	0.628
DOC_CYCLIN_RxL_1	56	64	PF00134	0.510
DOC_CYCLIN_yClb5_NLxxxL_5	59	65	PF00134	0.441
DOC_MAPK_gen_1	59	67	PF00069	0.434
DOC_MAPK_MEF2A_6	59	67	PF00069	0.434
DOC_MAPK_MEF2A_6	8	16	PF00069	0.625
DOC_USP7_MATH_1	111	115	PF00917	0.828
DOC_USP7_MATH_1	141	145	PF00917	0.577
DOC_USP7_MATH_1	180	184	PF00917	0.575
DOC_USP7_MATH_1	219	223	PF00917	0.611
DOC_USP7_MATH_1	258	262	PF00917	0.603
DOC_USP7_MATH_1	28	32	PF00917	0.755
DOC_USP7_MATH_1	297	301	PF00917	0.841
DOC_USP7_MATH_1	336	340	PF00917	0.594
DOC_USP7_MATH_1	375	379	PF00917	0.748
DOC_USP7_MATH_1	414	418	PF00917	0.561
DOC_USP7_UBL2_3	477	481	PF12436	0.573
DOC_WW_Pin1_4	8	13	PF00397	0.676
LIG_14-3-3_CanoR_1	37	46	PF00244	0.628
LIG_Actin_WH2_2	485	503	PF00022	0.419
LIG_BIR_II_1	1	5	PF00653	0.596
LIG_FHA_1	40	46	PF00498	0.552
LIG_FHA_2	51	57	PF00498	0.558
LIG_GBD_Chelix_1	488	496	PF00786	0.498
LIG_LIR_LC3C_4	484	487	PF02991	0.434
LIG_LIR_Nem_3	56	61	PF02991	0.535
LIG_NRBOX	550	556	PF00104	0.547
LIG_SH2_CRK	58	62	PF00017	0.533
LIG_SH2_STAT5	33	36	PF00017	0.641
LIG_SH3_3	11	17	PF00018	0.684
LIG_SH3_3	459	465	PF00018	0.605
LIG_SH3_3	539	545	PF00018	0.472
LIG_SUMO_SIM_anti_2	484	489	PF11976	0.429
LIG_SUMO_SIM_anti_2	96	101	PF11976	0.455
LIG_TRAF2_1	556	559	PF00917	0.620
MOD_CAAXbox	576	579	PF01239	0.595
MOD_CK1_1	29	35	PF00069	0.673
MOD_CK1_1	38	44	PF00069	0.591
MOD_CK1_1	47	53	PF00069	0.487
MOD_CK2_1	141	147	PF00069	0.600
MOD_CK2_1	180	186	PF00069	0.781
MOD_CK2_1	219	225	PF00069	0.644
MOD_CK2_1	258	264	PF00069	0.574
MOD_CK2_1	297	303	PF00069	0.644
MOD_CK2_1	336	342	PF00069	0.720
MOD_CK2_1	375	381	PF00069	0.593
MOD_CK2_1	414	420	PF00069	0.562
MOD_CK2_1	50	56	PF00069	0.565
MOD_CK2_1	553	559	PF00069	0.566
MOD_GlcNHglycan	1	4	PF01048	0.625
MOD_GlcNHglycan	144	147	PF01048	0.667
MOD_GlcNHglycan	183	186	PF01048	0.535
MOD_GlcNHglycan	222	225	PF01048	0.554
MOD_GlcNHglycan	26	29	PF01048	0.780
MOD_GlcNHglycan	261	264	PF01048	0.743
MOD_GlcNHglycan	300	303	PF01048	0.777
MOD_GlcNHglycan	339	342	PF01048	0.556
MOD_GlcNHglycan	378	381	PF01048	0.761
MOD_GlcNHglycan	417	420	PF01048	0.521
MOD_GlcNHglycan	466	469	PF01048	0.554
MOD_GlcNHglycan	50	53	PF01048	0.578
MOD_GlcNHglycan	520	523	PF01048	0.483
MOD_GlcNHglycan	550	554	PF01048	0.593
MOD_GlcNHglycan	555	558	PF01048	0.629
MOD_GSK3_1	20	27	PF00069	0.638
MOD_GSK3_1	29	36	PF00069	0.585
MOD_GSK3_1	37	44	PF00069	0.531
MOD_GSK3_1	46	53	PF00069	0.525
MOD_GSK3_1	549	556	PF00069	0.700
MOD_N-GLC_1	24	29	PF02516	0.637
MOD_N-GLC_1	563	568	PF02516	0.544
MOD_NEK2_1	35	40	PF00069	0.703
MOD_NEK2_1	46	51	PF00069	0.606
MOD_NEK2_1	82	87	PF00069	0.530
MOD_PIKK_1	26	32	PF00454	0.638
MOD_PKA_2	83	89	PF00069	0.561
MOD_Plk_1	20	26	PF00069	0.665
MOD_Plk_2-3	20	26	PF00069	0.597
MOD_Plk_4	41	47	PF00069	0.632
MOD_ProDKin_1	8	14	PF00069	0.676
MOD_SUMO_for_1	61	64	PF00179	0.524
TRG_DiLeu_BaEn_1	550	555	PF01217	0.587
TRG_ENDOCYTIC_2	58	61	PF00928	0.534
TRG_ENDOCYTIC_2	79	82	PF00928	0.620
TRG_NES_CRM1_1	484	498	PF08389	0.421

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9AHP6	Leishmania infantum	83%	100%
E9B466	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	71%