LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Uncharacterized protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania major
UniProt:
Q4Q3R3_LEIMA
TriTrypDb:
Length:
47

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q3R3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3R3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 28 30 PF00675 0.430
CLV_PCSK_KEX2_1 2 4 PF00082 0.466
CLV_PCSK_PC1ET2_1 2 4 PF00082 0.466
DEG_Nend_UBRbox_1 1 4 PF02207 0.475
DOC_MAPK_gen_1 29 37 PF00069 0.428
DOC_USP7_UBL2_3 12 16 PF12436 0.460
DOC_USP7_UBL2_3 26 30 PF12436 0.430
LIG_14-3-3_CanoR_1 21 26 PF00244 0.442
LIG_BRCT_BRCA1_1 21 25 PF00533 0.443
MOD_GlcNHglycan 32 35 PF01048 0.427
MOD_GlcNHglycan 7 10 PF01048 0.460
MOD_GSK3_1 20 27 PF00069 0.443
MOD_N-GLC_1 19 24 PF02516 0.451
MOD_PKA_2 20 26 PF00069 0.445
MOD_PKA_2 28 34 PF00069 0.427
MOD_SUMO_for_1 25 28 PF00179 0.433
MOD_SUMO_rev_2 22 32 PF00179 0.433

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS