Transposase

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Transposase

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q3Q5_LEIMA

TriTrypDb:

LmjF.33.2800 , LMJLV39_330039200 , LMJSD75_330038700

Length:

151

Annotations

LeishMANIAdb annotations

Probably not embedded into the membranes.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 19
NetGPI	no	yes: 0, no: 19

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	12
GO:0016020	membrane	2	10

Expansion

Sequence features

Q4Q3Q5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3Q5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	56	60	PF00656	0.626
CLV_NRD_NRD_1	126	128	PF00675	0.588
CLV_PCSK_KEX2_1	126	128	PF00082	0.588
CLV_PCSK_SKI1_1	109	113	PF00082	0.326
CLV_PCSK_SKI1_1	37	41	PF00082	0.388
DOC_PP1_RVXF_1	77	84	PF00149	0.551
DOC_WW_Pin1_4	131	136	PF00397	0.408
LIG_14-3-3_CanoR_1	109	118	PF00244	0.425
LIG_14-3-3_CanoR_1	126	130	PF00244	0.388
LIG_BIR_II_1	1	5	PF00653	0.672
LIG_FHA_2	54	60	PF00498	0.604
LIG_LIR_Nem_3	112	118	PF02991	0.386
LIG_LIR_Nem_3	128	133	PF02991	0.343
LIG_LIR_Nem_3	77	81	PF02991	0.622
LIG_LIR_Nem_3	94	99	PF02991	0.500
LIG_LYPXL_S_1	129	133	PF13949	0.576
LIG_LYPXL_yS_3	130	133	PF13949	0.378
LIG_PCNA_yPIPBox_3	97	105	PF02747	0.638
LIG_PTB_Phospho_1	145	151	PF10480	0.421
LIG_SH2_CRK	78	82	PF00017	0.549
LIG_SH2_STAT5	89	92	PF00017	0.540
LIG_SH3_3	126	132	PF00018	0.408
LIG_SH3_3	17	23	PF00018	0.637
LIG_UBA3_1	24	30	PF00899	0.497
MOD_CK1_1	12	18	PF00069	0.663
MOD_CK1_1	134	140	PF00069	0.510
MOD_Cter_Amidation	124	127	PF01082	0.472
MOD_GlcNHglycan	91	94	PF01048	0.370
MOD_NEK2_1	1	6	PF00069	0.673
MOD_NEK2_2	125	130	PF00069	0.358
MOD_PIKK_1	1	7	PF00454	0.558
MOD_PIKK_1	109	115	PF00454	0.464
MOD_PKA_1	10	16	PF00069	0.593
MOD_PKA_2	125	131	PF00069	0.361
MOD_ProDKin_1	131	137	PF00069	0.404
TRG_DiLeu_BaEn_1	71	76	PF01217	0.584
TRG_ENDOCYTIC_2	130	133	PF00928	0.378
TRG_ENDOCYTIC_2	78	81	PF00928	0.586
TRG_ER_diArg_1	65	68	PF00400	0.649
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.372

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTD3	Leptomonas seymouri	33%	94%
A0A0N1PDI5	Leptomonas seymouri	66%	100%
A0A0S4JQI6	Bodo saltans	43%	100%
A0A1X0NJU2	Trypanosomatidae	28%	100%
A0A1X0NR99	Trypanosomatidae	46%	100%
A0A3S7WP26	Leishmania donovani	32%	90%
A0A3S7X736	Leishmania donovani	90%	100%
A0A422N2T1	Trypanosoma rangeli	28%	100%
A0A422NKR0	Trypanosoma rangeli	44%	100%
A4H495	Leishmania braziliensis	33%	89%
A4HLZ1	Leishmania braziliensis	85%	99%
A4I9C1	Leishmania infantum	90%	100%
C9ZJA0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
C9ZUD9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
E9AKF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	90%
E9B4C0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	99%
V5BJW3	Trypanosoma cruzi	24%	100%
V5DB75	Trypanosoma cruzi	46%	100%