Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q3N7_LEIMA

TriTrypDb:

LmjF.33.2990 , LMJLV39_330042300 , LMJSD75_330041700

Length:

332

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q3N7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3N7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	111	115	PF00656	0.517
CLV_C14_Caspase3-7	231	235	PF00656	0.549
CLV_NRD_NRD_1	238	240	PF00675	0.635
CLV_NRD_NRD_1	304	306	PF00675	0.570
CLV_NRD_NRD_1	310	312	PF00675	0.569
CLV_PCSK_KEX2_1	298	300	PF00082	0.618
CLV_PCSK_KEX2_1	304	306	PF00082	0.546
CLV_PCSK_KEX2_1	310	312	PF00082	0.532
CLV_PCSK_KEX2_1	324	326	PF00082	0.476
CLV_PCSK_PC1ET2_1	298	300	PF00082	0.620
CLV_PCSK_PC1ET2_1	324	326	PF00082	0.593
CLV_PCSK_SKI1_1	295	299	PF00082	0.548
DEG_Nend_UBRbox_3	1	3	PF02207	0.658
DOC_ANK_TNKS_1	94	101	PF00023	0.555
DOC_CYCLIN_RxL_1	193	204	PF00134	0.383
DOC_PP4_MxPP_1	86	89	PF00568	0.557
DOC_USP7_MATH_1	223	227	PF00917	0.578
DOC_USP7_MATH_1	30	34	PF00917	0.656
DOC_USP7_UBL2_3	236	240	PF12436	0.600
LIG_14-3-3_CanoR_1	299	304	PF00244	0.678
LIG_14-3-3_CanoR_1	305	310	PF00244	0.740
LIG_CtBP_PxDLS_1	283	287	PF00389	0.548
LIG_deltaCOP1_diTrp_1	141	147	PF00928	0.437
LIG_EVH1_1	172	176	PF00568	0.420
LIG_FHA_1	288	294	PF00498	0.780
LIG_FHA_1	99	105	PF00498	0.601
LIG_LIR_Gen_1	140	150	PF02991	0.441
LIG_LIR_Gen_1	248	258	PF02991	0.537
LIG_LIR_Nem_3	140	145	PF02991	0.492
LIG_LIR_Nem_3	204	209	PF02991	0.394
LIG_LIR_Nem_3	211	216	PF02991	0.407
LIG_LYPXL_yS_3	202	205	PF13949	0.590
LIG_PCNA_PIPBox_1	188	197	PF02747	0.311
LIG_PCNA_yPIPBox_3	188	199	PF02747	0.308
LIG_Pex14_2	147	151	PF04695	0.467
LIG_RPA_C_Fungi	23	35	PF08784	0.614
LIG_SH2_CRK	195	199	PF00017	0.366
LIG_SH2_CRK	265	269	PF00017	0.594
LIG_SH2_SRC	265	268	PF00017	0.566
LIG_SH2_STAT3	187	190	PF00017	0.401
LIG_SH2_STAT3	8	11	PF00017	0.594
LIG_SH2_STAT5	209	212	PF00017	0.550
LIG_SH2_STAT5	213	216	PF00017	0.492
LIG_SH3_1	170	176	PF00018	0.436
LIG_SH3_3	170	176	PF00018	0.478
LIG_SH3_3	252	258	PF00018	0.718
LIG_SH3_3	261	267	PF00018	0.647
LIG_SH3_3	37	43	PF00018	0.539
LIG_TRFH_1	36	40	PF08558	0.579
LIG_TYR_ITIM	192	197	PF00017	0.411
LIG_TYR_ITIM	200	205	PF00017	0.362
LIG_WW_1	184	187	PF00397	0.419
MOD_CK1_1	226	232	PF00069	0.587
MOD_CK1_1	291	297	PF00069	0.618
MOD_GlcNHglycan	152	155	PF01048	0.381
MOD_GlcNHglycan	69	72	PF01048	0.661
MOD_GSK3_1	282	289	PF00069	0.662
MOD_N-GLC_1	106	111	PF02516	0.591
MOD_N-GLC_1	291	296	PF02516	0.612
MOD_NEK2_1	286	291	PF00069	0.590
MOD_PIKK_1	245	251	PF00454	0.665
MOD_PIKK_1	257	263	PF00454	0.509
MOD_PIKK_1	98	104	PF00454	0.629
MOD_PKA_1	240	246	PF00069	0.548
MOD_PKA_1	298	304	PF00069	0.605
MOD_PKA_2	287	293	PF00069	0.772
MOD_PKA_2	298	304	PF00069	0.543
MOD_Plk_1	106	112	PF00069	0.543
MOD_Plk_4	240	246	PF00069	0.579
MOD_Plk_4	3	9	PF00069	0.524
MOD_SUMO_for_1	317	320	PF00179	0.566
MOD_SUMO_rev_2	162	172	PF00179	0.519
MOD_SUMO_rev_2	229	238	PF00179	0.543
TRG_DiLeu_BaLyEn_6	193	198	PF01217	0.456
TRG_ENDOCYTIC_2	194	197	PF00928	0.438
TRG_ENDOCYTIC_2	202	205	PF00928	0.574
TRG_ENDOCYTIC_2	212	215	PF00928	0.400
TRG_ENDOCYTIC_2	217	220	PF00928	0.433
TRG_ER_diArg_1	303	305	PF00400	0.572
TRG_ER_diArg_1	309	311	PF00400	0.566
TRG_Pf-PMV_PEXEL_1	196	201	PF00026	0.378

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I737	Leptomonas seymouri	42%	97%
A0A3Q8IHR4	Leishmania donovani	82%	100%
A4HM09	Leishmania braziliensis	56%	100%
A4I9E1	Leishmania infantum	80%	100%
E9B4E0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	68%