Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q3L1_LEIMA

TriTrypDb:

LmjF.33.3250 , LMJLV39_330045800 , LMJSD75_330044600

Length:

354

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q3L1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3L1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	147	151	PF00656	0.668
CLV_C14_Caspase3-7	165	169	PF00656	0.477
CLV_NRD_NRD_1	103	105	PF00675	0.610
CLV_NRD_NRD_1	187	189	PF00675	0.821
CLV_NRD_NRD_1	215	217	PF00675	0.742
CLV_NRD_NRD_1	238	240	PF00675	0.793
CLV_NRD_NRD_1	289	291	PF00675	0.717
CLV_NRD_NRD_1	51	53	PF00675	0.653
CLV_NRD_NRD_1	8	10	PF00675	0.676
CLV_PCSK_KEX2_1	102	104	PF00082	0.613
CLV_PCSK_KEX2_1	118	120	PF00082	0.397
CLV_PCSK_KEX2_1	237	239	PF00082	0.792
CLV_PCSK_KEX2_1	289	291	PF00082	0.717
CLV_PCSK_KEX2_1	39	41	PF00082	0.659
CLV_PCSK_KEX2_1	51	53	PF00082	0.493
CLV_PCSK_PC1ET2_1	118	120	PF00082	0.609
CLV_PCSK_PC1ET2_1	39	41	PF00082	0.622
CLV_PCSK_SKI1_1	15	19	PF00082	0.642
CLV_PCSK_SKI1_1	39	43	PF00082	0.618
DEG_SPOP_SBC_1	183	187	PF00917	0.836
DEG_SPOP_SBC_1	196	200	PF00917	0.613
DOC_CKS1_1	233	238	PF01111	0.782
DOC_MAPK_gen_1	108	116	PF00069	0.565
DOC_MAPK_MEF2A_6	108	116	PF00069	0.565
DOC_USP7_MATH_1	13	17	PF00917	0.548
DOC_USP7_MATH_1	130	134	PF00917	0.592
DOC_USP7_MATH_1	182	186	PF00917	0.839
DOC_USP7_MATH_1	267	271	PF00917	0.744
DOC_USP7_MATH_1	283	287	PF00917	0.727
DOC_USP7_MATH_1	319	323	PF00917	0.716
DOC_USP7_MATH_1	327	331	PF00917	0.772
DOC_USP7_MATH_1	333	337	PF00917	0.662
DOC_USP7_UBL2_3	113	117	PF12436	0.441
DOC_USP7_UBL2_3	27	31	PF12436	0.561
DOC_USP7_UBL2_3	70	74	PF12436	0.619
DOC_USP7_UBL2_3	76	80	PF12436	0.532
DOC_WW_Pin1_4	172	177	PF00397	0.765
DOC_WW_Pin1_4	232	237	PF00397	0.781
DOC_WW_Pin1_4	281	286	PF00397	0.818
LIG_14-3-3_CanoR_1	188	194	PF00244	0.811
LIG_14-3-3_CanoR_1	241	246	PF00244	0.605
LIG_14-3-3_CanoR_1	40	46	PF00244	0.671
LIG_BIR_II_1	1	5	PF00653	0.477
LIG_FHA_1	137	143	PF00498	0.666
LIG_FHA_1	197	203	PF00498	0.659
LIG_FHA_1	267	273	PF00498	0.608
LIG_FHA_1	339	345	PF00498	0.702
LIG_FHA_2	198	204	PF00498	0.705
LIG_PDZ_Class_2	349	354	PF00595	0.748
LIG_SH3_2	233	238	PF14604	0.782
LIG_SH3_3	19	25	PF00018	0.702
LIG_SH3_3	223	229	PF00018	0.691
LIG_SH3_3	230	236	PF00018	0.687
LIG_SH3_3	244	250	PF00018	0.594
LIG_TRAF2_1	132	135	PF00917	0.633
LIG_TRAF2_1	271	274	PF00917	0.799
LIG_TRAF2_1	5	8	PF00917	0.506
MOD_CDK_SPK_2	232	237	PF00069	0.781
MOD_CDK_SPxK_1	172	178	PF00069	0.585
MOD_CDK_SPxK_1	232	238	PF00069	0.781
MOD_CDK_SPxxK_3	232	239	PF00069	0.783
MOD_CK1_1	187	193	PF00069	0.825
MOD_CK1_1	197	203	PF00069	0.668
MOD_CK1_1	255	261	PF00069	0.599
MOD_CK2_1	197	203	PF00069	0.771
MOD_CK2_1	298	304	PF00069	0.717
MOD_GlcNHglycan	243	246	PF01048	0.759
MOD_GlcNHglycan	254	257	PF01048	0.752
MOD_GlcNHglycan	269	272	PF01048	0.561
MOD_GlcNHglycan	274	278	PF01048	0.599
MOD_GlcNHglycan	300	303	PF01048	0.705
MOD_GlcNHglycan	329	332	PF01048	0.800
MOD_GlcNHglycan	335	338	PF01048	0.707
MOD_GSK3_1	117	124	PF00069	0.491
MOD_GSK3_1	183	190	PF00069	0.817
MOD_GSK3_1	197	204	PF00069	0.586
MOD_GSK3_1	206	213	PF00069	0.700
MOD_GSK3_1	248	255	PF00069	0.800
MOD_GSK3_1	281	288	PF00069	0.789
MOD_GSK3_1	315	322	PF00069	0.732
MOD_GSK3_1	327	334	PF00069	0.655
MOD_N-GLC_1	194	199	PF02516	0.766
MOD_NEK2_1	332	337	PF00069	0.683
MOD_NEK2_1	41	46	PF00069	0.668
MOD_NEK2_2	13	18	PF00069	0.535
MOD_PIKK_1	130	136	PF00454	0.594
MOD_PIKK_1	187	193	PF00454	0.763
MOD_PIKK_1	283	289	PF00454	0.755
MOD_PKA_1	117	123	PF00069	0.443
MOD_PKA_1	231	237	PF00069	0.741
MOD_PKA_2	187	193	PF00069	0.825
MOD_PKA_2	315	321	PF00069	0.738
MOD_PKB_1	239	247	PF00069	0.749
MOD_Plk_4	197	203	PF00069	0.607
MOD_ProDKin_1	172	178	PF00069	0.770
MOD_ProDKin_1	232	238	PF00069	0.781
MOD_ProDKin_1	281	287	PF00069	0.819
MOD_SUMO_for_1	75	78	PF00179	0.549
MOD_SUMO_for_1	79	82	PF00179	0.485
MOD_SUMO_for_1	85	88	PF00179	0.499
MOD_SUMO_for_1	91	94	PF00179	0.400
MOD_SUMO_rev_2	165	173	PF00179	0.564
MOD_SUMO_rev_2	7	11	PF00179	0.507
TRG_DiLeu_BaEn_1	141	146	PF01217	0.620
TRG_ER_diArg_1	101	104	PF00400	0.632
TRG_ER_diArg_1	236	239	PF00400	0.787
TRG_ER_diArg_1	289	291	PF00400	0.709
TRG_NLS_Bipartite_1	39	56	PF00514	0.605
TRG_NLS_MonoExtN_4	51	56	PF00514	0.665

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IUB2	Leishmania donovani	88%	77%
A4HM33	Leishmania braziliensis	54%	100%
A4I9G6	Leishmania infantum	88%	77%
E9B4G4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	92%