Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q3G9_LEIMA

TriTrypDb:

LmjF.34.0390 , LMJLV39_340009300 , LMJSD75_340009300

Length:

568

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 3, no: 4
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

Q4Q3G9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3G9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	23	27	PF00656	0.661
CLV_NRD_NRD_1	32	34	PF00675	0.651
CLV_NRD_NRD_1	51	53	PF00675	0.410
CLV_NRD_NRD_1	513	515	PF00675	0.602
CLV_PCSK_FUR_1	511	515	PF00082	0.608
CLV_PCSK_KEX2_1	32	34	PF00082	0.651
CLV_PCSK_KEX2_1	511	513	PF00082	0.600
CLV_PCSK_SKI1_1	163	167	PF00082	0.512
CLV_PCSK_SKI1_1	213	217	PF00082	0.498
CLV_PCSK_SKI1_1	32	36	PF00082	0.547
CLV_Separin_Metazoa	29	33	PF03568	0.639
DOC_CKS1_1	417	422	PF01111	0.505
DOC_MAPK_DCC_7	195	205	PF00069	0.505
DOC_PP4_FxxP_1	327	330	PF00568	0.564
DOC_PP4_FxxP_1	333	336	PF00568	0.548
DOC_PP4_FxxP_1	353	356	PF00568	0.285
DOC_USP7_MATH_1	101	105	PF00917	0.658
DOC_USP7_MATH_1	189	193	PF00917	0.748
DOC_USP7_MATH_1	2	6	PF00917	0.441
DOC_USP7_MATH_1	259	263	PF00917	0.669
DOC_USP7_MATH_1	286	290	PF00917	0.454
DOC_USP7_MATH_1	336	340	PF00917	0.621
DOC_USP7_MATH_1	354	358	PF00917	0.356
DOC_WW_Pin1_4	238	243	PF00397	0.478
DOC_WW_Pin1_4	352	357	PF00397	0.540
DOC_WW_Pin1_4	392	397	PF00397	0.842
DOC_WW_Pin1_4	398	403	PF00397	0.568
DOC_WW_Pin1_4	416	421	PF00397	0.425
LIG_14-3-3_CanoR_1	152	159	PF00244	0.496
LIG_14-3-3_CanoR_1	213	222	PF00244	0.451
LIG_14-3-3_CanoR_1	334	344	PF00244	0.445
LIG_14-3-3_CanoR_1	444	451	PF00244	0.524
LIG_APCC_ABBA_1	364	369	PF00400	0.457
LIG_BRCT_BRCA1_1	163	167	PF00533	0.479
LIG_deltaCOP1_diTrp_1	515	523	PF00928	0.596
LIG_FHA_1	177	183	PF00498	0.615
LIG_FHA_1	204	210	PF00498	0.431
LIG_FHA_1	216	222	PF00498	0.438
LIG_FHA_1	235	241	PF00498	0.435
LIG_FHA_1	264	270	PF00498	0.520
LIG_FHA_1	373	379	PF00498	0.552
LIG_FHA_1	416	422	PF00498	0.464
LIG_FHA_1	42	48	PF00498	0.643
LIG_FHA_1	428	434	PF00498	0.459
LIG_FHA_1	445	451	PF00498	0.526
LIG_FHA_1	479	485	PF00498	0.452
LIG_FHA_2	186	192	PF00498	0.620
LIG_FHA_2	21	27	PF00498	0.650
LIG_FHA_2	357	363	PF00498	0.515
LIG_FHA_2	402	408	PF00498	0.624
LIG_LIR_Apic_2	325	330	PF02991	0.531
LIG_LIR_Gen_1	293	298	PF02991	0.503
LIG_LIR_Gen_1	375	381	PF02991	0.592
LIG_LIR_Gen_1	411	420	PF02991	0.577
LIG_LIR_Gen_1	490	498	PF02991	0.459
LIG_LIR_Nem_3	164	170	PF02991	0.409
LIG_LIR_Nem_3	293	297	PF02991	0.478
LIG_LIR_Nem_3	375	380	PF02991	0.587
LIG_LIR_Nem_3	411	415	PF02991	0.660
LIG_LIR_Nem_3	448	454	PF02991	0.545
LIG_LIR_Nem_3	490	496	PF02991	0.468
LIG_LIR_Nem_3	532	538	PF02991	0.485
LIG_LYPXL_yS_3	479	482	PF13949	0.463
LIG_SH2_CRK	294	298	PF00017	0.489
LIG_SH2_CRK	412	416	PF00017	0.589
LIG_SH2_GRB2like	22	25	PF00017	0.579
LIG_SH2_NCK_1	538	542	PF00017	0.484
LIG_SH2_PTP2	377	380	PF00017	0.611
LIG_SH2_STAP1	153	157	PF00017	0.496
LIG_SH2_STAP1	294	298	PF00017	0.522
LIG_SH2_STAP1	446	450	PF00017	0.476
LIG_SH2_STAT3	93	96	PF00017	0.511
LIG_SH2_STAT5	146	149	PF00017	0.444
LIG_SH2_STAT5	17	20	PF00017	0.587
LIG_SH2_STAT5	210	213	PF00017	0.507
LIG_SH2_STAT5	22	25	PF00017	0.629
LIG_SH2_STAT5	377	380	PF00017	0.681
LIG_SH2_STAT5	39	42	PF00017	0.658
LIG_SH2_STAT5	446	449	PF00017	0.549
LIG_SH2_STAT5	520	523	PF00017	0.562
LIG_SH2_STAT5	529	532	PF00017	0.473
LIG_SH2_STAT5	538	541	PF00017	0.325
LIG_SH2_STAT5	557	560	PF00017	0.366
LIG_SH2_STAT5	93	96	PF00017	0.448
LIG_SH3_1	414	420	PF00018	0.493
LIG_SH3_3	111	117	PF00018	0.683
LIG_SH3_3	171	177	PF00018	0.581
LIG_SH3_3	248	254	PF00018	0.647
LIG_SH3_3	266	272	PF00018	0.513
LIG_SH3_3	414	420	PF00018	0.486
LIG_SH3_3	477	483	PF00018	0.475
LIG_SUMO_SIM_anti_2	231	237	PF11976	0.403
LIG_SUMO_SIM_par_1	201	207	PF11976	0.454
LIG_TYR_ITIM	292	297	PF00017	0.473
LIG_TYR_ITIM	410	415	PF00017	0.521
LIG_TYR_ITSM	373	380	PF00017	0.494
LIG_UBA3_1	166	172	PF00899	0.450
LIG_WRC_WIRS_1	337	342	PF05994	0.534
LIG_WW_3	29	33	PF00397	0.639
LIG_WW_3	395	399	PF00397	0.586
MOD_CDC14_SPxK_1	395	398	PF00782	0.594
MOD_CDK_SPxK_1	392	398	PF00069	0.597
MOD_CK1_1	228	234	PF00069	0.554
MOD_CK1_1	312	318	PF00069	0.571
MOD_CK1_1	401	407	PF00069	0.607
MOD_CK1_1	507	513	PF00069	0.504
MOD_CK1_1	546	552	PF00069	0.453
MOD_CK1_1	560	566	PF00069	0.503
MOD_CK2_1	185	191	PF00069	0.759
MOD_CK2_1	336	342	PF00069	0.497
MOD_CK2_1	356	362	PF00069	0.383
MOD_CK2_1	401	407	PF00069	0.698
MOD_CK2_1	528	534	PF00069	0.521
MOD_CK2_1	86	92	PF00069	0.489
MOD_DYRK1A_RPxSP_1	398	402	PF00069	0.557
MOD_GlcNHglycan	138	141	PF01048	0.478
MOD_GlcNHglycan	163	166	PF01048	0.486
MOD_GlcNHglycan	213	216	PF01048	0.457
MOD_GlcNHglycan	345	348	PF01048	0.409
MOD_GlcNHglycan	356	359	PF01048	0.580
MOD_GlcNHglycan	550	553	PF01048	0.445
MOD_GlcNHglycan	559	562	PF01048	0.511
MOD_GSK3_1	185	192	PF00069	0.751
MOD_GSK3_1	209	216	PF00069	0.508
MOD_GSK3_1	230	237	PF00069	0.423
MOD_GSK3_1	259	266	PF00069	0.695
MOD_GSK3_1	286	293	PF00069	0.416
MOD_GSK3_1	352	359	PF00069	0.633
MOD_GSK3_1	392	399	PF00069	0.846
MOD_GSK3_1	474	481	PF00069	0.369
MOD_GSK3_1	539	546	PF00069	0.554
MOD_N-GLC_1	134	139	PF02516	0.551
MOD_N-GLC_1	189	194	PF02516	0.709
MOD_N-GLC_1	322	327	PF02516	0.529
MOD_N-GLC_1	41	46	PF02516	0.647
MOD_N-GLC_1	505	510	PF02516	0.669
MOD_NEK2_1	145	150	PF00069	0.500
MOD_NEK2_1	151	156	PF00069	0.591
MOD_NEK2_1	20	25	PF00069	0.707
MOD_NEK2_1	203	208	PF00069	0.422
MOD_NEK2_1	234	239	PF00069	0.479
MOD_NEK2_2	356	361	PF00069	0.501
MOD_PIKK_1	101	107	PF00454	0.562
MOD_PIKK_1	41	47	PF00454	0.664
MOD_PIKK_1	428	434	PF00454	0.548
MOD_PKA_2	151	157	PF00069	0.509
MOD_PKA_2	487	493	PF00069	0.575
MOD_PKA_2	536	542	PF00069	0.465
MOD_PKA_2	543	549	PF00069	0.385
MOD_Plk_1	189	195	PF00069	0.594
MOD_Plk_1	322	328	PF00069	0.616
MOD_Plk_1	458	464	PF00069	0.461
MOD_Plk_4	2	8	PF00069	0.553
MOD_Plk_4	230	236	PF00069	0.398
MOD_Plk_4	293	299	PF00069	0.438
MOD_Plk_4	560	566	PF00069	0.482
MOD_ProDKin_1	238	244	PF00069	0.481
MOD_ProDKin_1	352	358	PF00069	0.541
MOD_ProDKin_1	392	398	PF00069	0.842
MOD_ProDKin_1	416	422	PF00069	0.504
MOD_SUMO_rev_2	382	386	PF00179	0.684
TRG_DiLeu_BaEn_1	43	48	PF01217	0.640
TRG_ENDOCYTIC_2	138	141	PF00928	0.534
TRG_ENDOCYTIC_2	17	20	PF00928	0.631
TRG_ENDOCYTIC_2	294	297	PF00928	0.485
TRG_ENDOCYTIC_2	37	40	PF00928	0.435
TRG_ENDOCYTIC_2	377	380	PF00928	0.681
TRG_ENDOCYTIC_2	412	415	PF00928	0.588
TRG_ENDOCYTIC_2	479	482	PF00928	0.455
TRG_ENDOCYTIC_2	493	496	PF00928	0.388
TRG_ENDOCYTIC_2	97	100	PF00928	0.502
TRG_ER_diArg_1	31	33	PF00400	0.649
TRG_ER_diArg_1	317	320	PF00400	0.605
TRG_ER_diArg_1	511	514	PF00400	0.615
TRG_NES_CRM1_1	464	478	PF08389	0.513

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HW70	Leptomonas seymouri	62%	97%
A0A1X0PA87	Trypanosomatidae	41%	100%
A0A3S7X7F2	Leishmania donovani	92%	99%
A4HAF2	Leishmania braziliensis	24%	100%
A4HAF3	Leishmania braziliensis	77%	99%
A4I9K9	Leishmania infantum	92%	99%