40S ribosomal protein S25

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ribosomal protein S25

Species:

Leishmania major

UniProt:

Q4Q3G4_LEIMA

TriTrypDb:

LmjF.25.1190 , LMJLV39_250018800 , LMJSD75_250018600

Length:

121

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0015935	small ribosomal subunit	4	3
GO:0022627	cytosolic small ribosomal subunit	5	3
GO:0032991	protein-containing complex	1	15
GO:0044391	ribosomal subunit	3	3
GO:1990904	ribonucleoprotein complex	2	15
GO:0005840	ribosome	5	12
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

Q4Q3G4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3G4

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	3
GO:0005198	structural molecule activity	1	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	18	22	PF00082	0.254
CLV_PCSK_SKI1_1	33	37	PF00082	0.328
CLV_PCSK_SKI1_1	58	62	PF00082	0.360
CLV_PCSK_SKI1_1	9	13	PF00082	0.393
DEG_APCC_DBOX_1	84	92	PF00400	0.387
DOC_CKS1_1	59	64	PF01111	0.328
DOC_MAPK_gen_1	68	75	PF00069	0.328
DOC_MAPK_MEF2A_6	68	75	PF00069	0.328
DOC_USP7_UBL2_3	18	22	PF12436	0.426
DOC_USP7_UBL2_3	25	29	PF12436	0.328
DOC_WW_Pin1_4	58	63	PF00397	0.331
LIG_FHA_1	100	106	PF00498	0.458
LIG_FHA_1	59	65	PF00498	0.337
LIG_LIR_Gen_1	45	55	PF02991	0.474
LIG_LIR_Gen_1	98	109	PF02991	0.620
LIG_LIR_Nem_3	45	50	PF02991	0.482
LIG_LIR_Nem_3	98	104	PF02991	0.358
LIG_SH2_CRK	101	105	PF00017	0.474
LIG_SH2_CRK	47	51	PF00017	0.406
LIG_SH2_CRK	57	61	PF00017	0.265
LIG_SH2_STAP1	101	105	PF00017	0.387
LIG_SH2_STAT5	101	104	PF00017	0.344
MOD_CK1_1	63	69	PF00069	0.331
MOD_CK1_1	93	99	PF00069	0.329
MOD_GSK3_1	21	28	PF00069	0.340
MOD_GSK3_1	95	102	PF00069	0.435
MOD_PKA_1	21	27	PF00069	0.340
MOD_Plk_2-3	43	49	PF00069	0.328
MOD_Plk_4	60	66	PF00069	0.330
MOD_ProDKin_1	58	64	PF00069	0.331
MOD_SUMO_for_1	11	14	PF00179	0.458
TRG_ENDOCYTIC_2	101	104	PF00928	0.418
TRG_ENDOCYTIC_2	47	50	PF00928	0.406
TRG_ENDOCYTIC_2	57	60	PF00928	0.265
TRG_NLS_MonoExtC_3	8	14	PF00514	0.344

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4KIW3	Bodo saltans	70%	100%
A0A1D8PNQ6	Candida albicans (strain SC5314 / ATCC MYA-2876)	45%	100%
A0A1X0P8I6	Trypanosomatidae	72%	100%
A0A3Q8INE9	Leishmania donovani	100%	100%
A0A3R7MV32	Trypanosoma rangeli	67%	100%
A4HAF8	Leishmania braziliensis	100%	100%
A4HE62	Leishmania braziliensis	99%	100%
C9ZK09	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
D0A1X6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	73%	100%
E9AXJ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9B4L2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
P62851	Homo sapiens	49%	97%
P62852	Mus musculus	49%	97%
P62853	Rattus norvegicus	49%	97%
Q03409	Dictyostelium discoideum	43%	100%
Q4Q9X4	Leishmania major	100%	100%
Q56JX5	Bos taurus	49%	97%
Q6PBI5	Danio rerio	48%	98%
Q6Q311	Ovis aries	49%	97%
Q7SC06	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	45%	100%
Q8STD9	Encephalitozoon cuniculi (strain GB-M1)	27%	100%
Q90YP9	Ictalurus punctatus	47%	98%
Q9N9V4	Leishmania infantum	100%	100%
V5BRV7	Trypanosoma cruzi	70%	100%