Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q3G3_LEIMA

TriTrypDb:

LmjF.34.0450 , LMJLV39_340009900 , LMJSD75_340009900

Length:

936

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q3G3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3G3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	124	128	PF00656	0.693
CLV_C14_Caspase3-7	51	55	PF00656	0.684
CLV_C14_Caspase3-7	689	693	PF00656	0.725
CLV_C14_Caspase3-7	900	904	PF00656	0.550
CLV_NRD_NRD_1	114	116	PF00675	0.757
CLV_NRD_NRD_1	415	417	PF00675	0.715
CLV_NRD_NRD_1	422	424	PF00675	0.707
CLV_NRD_NRD_1	459	461	PF00675	0.660
CLV_NRD_NRD_1	703	705	PF00675	0.793
CLV_NRD_NRD_1	744	746	PF00675	0.737
CLV_NRD_NRD_1	756	758	PF00675	0.568
CLV_NRD_NRD_1	928	930	PF00675	0.671
CLV_PCSK_KEX2_1	114	116	PF00082	0.757
CLV_PCSK_KEX2_1	192	194	PF00082	0.672
CLV_PCSK_KEX2_1	415	417	PF00082	0.715
CLV_PCSK_KEX2_1	422	424	PF00082	0.707
CLV_PCSK_KEX2_1	515	517	PF00082	0.666
CLV_PCSK_KEX2_1	703	705	PF00082	0.791
CLV_PCSK_KEX2_1	743	745	PF00082	0.691
CLV_PCSK_KEX2_1	756	758	PF00082	0.558
CLV_PCSK_KEX2_1	854	856	PF00082	0.531
CLV_PCSK_KEX2_1	879	881	PF00082	0.683
CLV_PCSK_KEX2_1	928	930	PF00082	0.671
CLV_PCSK_PC1ET2_1	192	194	PF00082	0.672
CLV_PCSK_PC1ET2_1	515	517	PF00082	0.666
CLV_PCSK_PC1ET2_1	854	856	PF00082	0.531
CLV_PCSK_PC1ET2_1	879	881	PF00082	0.652
CLV_PCSK_SKI1_1	166	170	PF00082	0.605
CLV_PCSK_SKI1_1	42	46	PF00082	0.701
CLV_PCSK_SKI1_1	490	494	PF00082	0.666
CLV_PCSK_SKI1_1	515	519	PF00082	0.620
CLV_PCSK_SKI1_1	524	528	PF00082	0.545
CLV_PCSK_SKI1_1	857	861	PF00082	0.637
DEG_APCC_KENBOX_2	140	144	PF00400	0.729
DEG_SCF_FBW7_1	25	31	PF00400	0.742
DEG_SCF_FBW7_1	346	351	PF00400	0.701
DEG_SPOP_SBC_1	15	19	PF00917	0.658
DEG_SPOP_SBC_1	229	233	PF00917	0.582
DEG_SPOP_SBC_1	33	37	PF00917	0.571
DEG_SPOP_SBC_1	693	697	PF00917	0.687
DEG_SPOP_SBC_1	758	762	PF00917	0.647
DEG_SPOP_SBC_1	831	835	PF00917	0.658
DOC_CKS1_1	25	30	PF01111	0.742
DOC_CYCLIN_yCln2_LP_2	261	267	PF00134	0.632
DOC_MAPK_DCC_7	38	46	PF00069	0.631
DOC_MAPK_gen_1	527	538	PF00069	0.539
DOC_MAPK_gen_1	577	586	PF00069	0.494
DOC_MAPK_gen_1	671	679	PF00069	0.599
DOC_MAPK_MEF2A_6	673	681	PF00069	0.599
DOC_PP2B_LxvP_1	212	215	PF13499	0.648
DOC_PP2B_LxvP_1	261	264	PF13499	0.664
DOC_PP2B_LxvP_1	325	328	PF13499	0.768
DOC_PP2B_LxvP_1	433	436	PF13499	0.673
DOC_PP2B_LxvP_1	493	496	PF13499	0.641
DOC_PP4_FxxP_1	22	25	PF00568	0.741
DOC_PP4_FxxP_1	360	363	PF00568	0.742
DOC_PP4_FxxP_1	40	43	PF00568	0.559
DOC_PP4_MxPP_1	361	364	PF00568	0.711
DOC_USP7_MATH_1	146	150	PF00917	0.725
DOC_USP7_MATH_1	196	200	PF00917	0.680
DOC_USP7_MATH_1	2	6	PF00917	0.680
DOC_USP7_MATH_1	201	205	PF00917	0.626
DOC_USP7_MATH_1	229	233	PF00917	0.663
DOC_USP7_MATH_1	234	238	PF00917	0.614
DOC_USP7_MATH_1	257	261	PF00917	0.681
DOC_USP7_MATH_1	279	283	PF00917	0.600
DOC_USP7_MATH_1	309	313	PF00917	0.685
DOC_USP7_MATH_1	34	38	PF00917	0.708
DOC_USP7_MATH_1	348	352	PF00917	0.785
DOC_USP7_MATH_1	517	521	PF00917	0.534
DOC_USP7_MATH_1	596	600	PF00917	0.642
DOC_USP7_MATH_1	629	633	PF00917	0.735
DOC_USP7_MATH_1	682	686	PF00917	0.648
DOC_USP7_MATH_1	710	714	PF00917	0.695
DOC_USP7_MATH_1	747	751	PF00917	0.682
DOC_USP7_MATH_1	758	762	PF00917	0.598
DOC_USP7_MATH_1	802	806	PF00917	0.654
DOC_USP7_MATH_1	815	819	PF00917	0.592
DOC_USP7_MATH_1	831	835	PF00917	0.549
DOC_USP7_MATH_1	902	906	PF00917	0.649
DOC_USP7_MATH_1	98	102	PF00917	0.717
DOC_USP7_MATH_2	474	480	PF00917	0.571
DOC_USP7_UBL2_3	524	528	PF12436	0.612
DOC_USP7_UBL2_3	669	673	PF12436	0.736
DOC_WW_Pin1_4	21	26	PF00397	0.748
DOC_WW_Pin1_4	213	218	PF00397	0.552
DOC_WW_Pin1_4	259	264	PF00397	0.647
DOC_WW_Pin1_4	28	33	PF00397	0.630
DOC_WW_Pin1_4	305	310	PF00397	0.743
DOC_WW_Pin1_4	312	317	PF00397	0.620
DOC_WW_Pin1_4	344	349	PF00397	0.705
DOC_WW_Pin1_4	391	396	PF00397	0.654
DOC_WW_Pin1_4	407	412	PF00397	0.571
DOC_WW_Pin1_4	5	10	PF00397	0.649
DOC_WW_Pin1_4	592	597	PF00397	0.657
DOC_WW_Pin1_4	601	606	PF00397	0.576
DOC_WW_Pin1_4	620	625	PF00397	0.708
DOC_WW_Pin1_4	631	636	PF00397	0.636
DOC_WW_Pin1_4	714	719	PF00397	0.685
DOC_WW_Pin1_4	784	789	PF00397	0.696
DOC_WW_Pin1_4	795	800	PF00397	0.606
LIG_14-3-3_CanoR_1	193	202	PF00244	0.588
LIG_14-3-3_CanoR_1	230	239	PF00244	0.569
LIG_14-3-3_CanoR_1	26	32	PF00244	0.720
LIG_14-3-3_CanoR_1	294	302	PF00244	0.647
LIG_14-3-3_CanoR_1	353	358	PF00244	0.734
LIG_14-3-3_CanoR_1	422	427	PF00244	0.789
LIG_14-3-3_CanoR_1	428	436	PF00244	0.680
LIG_14-3-3_CanoR_1	460	469	PF00244	0.590
LIG_14-3-3_CanoR_1	579	585	PF00244	0.651
LIG_14-3-3_CanoR_1	662	668	PF00244	0.701
LIG_14-3-3_CanoR_1	736	741	PF00244	0.727
LIG_14-3-3_CanoR_1	783	788	PF00244	0.711
LIG_14-3-3_CanoR_1	864	873	PF00244	0.719
LIG_14-3-3_CanoR_1	97	105	PF00244	0.616
LIG_BIR_II_1	1	5	PF00653	0.631
LIG_BRCT_BRCA1_1	234	238	PF00533	0.667
LIG_BRCT_BRCA1_1	36	40	PF00533	0.568
LIG_BRCT_BRCA1_1	644	648	PF00533	0.754
LIG_CaM_IQ_9	508	523	PF13499	0.499
LIG_CaM_IQ_9	921	936	PF13499	0.681
LIG_deltaCOP1_diTrp_1	640	648	PF00928	0.738
LIG_EVH1_1	495	499	PF00568	0.553
LIG_FHA_1	152	158	PF00498	0.687
LIG_FHA_1	195	201	PF00498	0.586
LIG_FHA_1	394	400	PF00498	0.757
LIG_FHA_1	428	434	PF00498	0.748
LIG_FHA_1	596	602	PF00498	0.700
LIG_FHA_1	811	817	PF00498	0.634
LIG_FHA_1	824	830	PF00498	0.618
LIG_FHA_2	122	128	PF00498	0.714
LIG_FHA_2	299	305	PF00498	0.661
LIG_FHA_2	505	511	PF00498	0.619
LIG_FHA_2	898	904	PF00498	0.553
LIG_Integrin_isoDGR_2	404	406	PF01839	0.730
LIG_LIR_Apic_2	19	25	PF02991	0.735
LIG_LIR_Apic_2	236	242	PF02991	0.672
LIG_LIR_Apic_2	359	363	PF02991	0.738
LIG_LIR_Apic_2	37	43	PF02991	0.562
LIG_LIR_Gen_1	510	517	PF02991	0.609
LIG_LIR_Nem_3	483	488	PF02991	0.542
LIG_LIR_Nem_3	510	514	PF02991	0.614
LIG_NRP_CendR_1	934	936	PF00754	0.675
LIG_SH2_CRK	239	243	PF00017	0.679
LIG_SH2_NCK_1	239	243	PF00017	0.581
LIG_SH3_3	22	28	PF00018	0.744
LIG_SH3_3	261	267	PF00018	0.632
LIG_SH3_3	317	323	PF00018	0.735
LIG_SH3_3	325	331	PF00018	0.692
LIG_SH3_3	493	499	PF00018	0.625
LIG_SH3_3	704	710	PF00018	0.670
LIG_SH3_3	735	741	PF00018	0.770
LIG_SUMO_SIM_par_1	289	295	PF11976	0.646
LIG_TRAF2_1	532	535	PF00917	0.525
LIG_TRAF2_1	604	607	PF00917	0.540
LIG_TRAF2_1	886	889	PF00917	0.663
LIG_TRAF2_2	498	503	PF00917	0.616
LIG_WRC_WIRS_1	477	482	PF05994	0.604
LIG_WRC_WIRS_1	485	490	PF05994	0.450
LIG_WRC_WIRS_1	924	929	PF05994	0.681
MOD_CDK_SPK_2	21	26	PF00069	0.718
MOD_CDK_SPxK_1	620	626	PF00069	0.667
MOD_CK1_1	149	155	PF00069	0.775
MOD_CK1_1	21	27	PF00069	0.718
MOD_CK1_1	216	222	PF00069	0.702
MOD_CK1_1	225	231	PF00069	0.694
MOD_CK1_1	232	238	PF00069	0.635
MOD_CK1_1	280	286	PF00069	0.690
MOD_CK1_1	298	304	PF00069	0.576
MOD_CK1_1	308	314	PF00069	0.671
MOD_CK1_1	321	327	PF00069	0.544
MOD_CK1_1	338	344	PF00069	0.617
MOD_CK1_1	351	357	PF00069	0.630
MOD_CK1_1	391	397	PF00069	0.645
MOD_CK1_1	431	437	PF00069	0.754
MOD_CK1_1	462	468	PF00069	0.625
MOD_CK1_1	5	11	PF00069	0.622
MOD_CK1_1	520	526	PF00069	0.578
MOD_CK1_1	587	593	PF00069	0.674
MOD_CK1_1	595	601	PF00069	0.632
MOD_CK1_1	67	73	PF00069	0.693
MOD_CK1_1	694	700	PF00069	0.761
MOD_CK1_1	725	731	PF00069	0.651
MOD_CK1_1	760	766	PF00069	0.727
MOD_CK1_1	786	792	PF00069	0.658
MOD_CK1_1	800	806	PF00069	0.592
MOD_CK1_1	807	813	PF00069	0.681
MOD_CK1_1	823	829	PF00069	0.621
MOD_CK1_1	834	840	PF00069	0.594
MOD_CK1_1	866	872	PF00069	0.679
MOD_CK1_1	923	929	PF00069	0.719
MOD_CK2_1	279	285	PF00069	0.664
MOD_CK2_1	298	304	PF00069	0.496
MOD_CK2_1	431	437	PF00069	0.674
MOD_CK2_1	601	607	PF00069	0.694
MOD_CK2_1	682	688	PF00069	0.759
MOD_CK2_1	694	700	PF00069	0.765
MOD_CK2_1	74	80	PF00069	0.697
MOD_CK2_1	762	768	PF00069	0.679
MOD_CK2_1	830	836	PF00069	0.736
MOD_GlcNHglycan	203	206	PF01048	0.671
MOD_GlcNHglycan	224	227	PF01048	0.721
MOD_GlcNHglycan	232	235	PF01048	0.694
MOD_GlcNHglycan	243	246	PF01048	0.545
MOD_GlcNHglycan	279	282	PF01048	0.671
MOD_GlcNHglycan	297	300	PF01048	0.496
MOD_GlcNHglycan	320	323	PF01048	0.805
MOD_GlcNHglycan	337	340	PF01048	0.628
MOD_GlcNHglycan	385	388	PF01048	0.659
MOD_GlcNHglycan	440	443	PF01048	0.682
MOD_GlcNHglycan	454	457	PF01048	0.634
MOD_GlcNHglycan	464	467	PF01048	0.643
MOD_GlcNHglycan	586	589	PF01048	0.683
MOD_GlcNHglycan	617	621	PF01048	0.682
MOD_GlcNHglycan	712	715	PF01048	0.750
MOD_GlcNHglycan	789	792	PF01048	0.585
MOD_GlcNHglycan	804	807	PF01048	0.629
MOD_GlcNHglycan	868	871	PF01048	0.628
MOD_GlcNHglycan	884	887	PF01048	0.535
MOD_GSK3_1	14	21	PF00069	0.738
MOD_GSK3_1	146	153	PF00069	0.746
MOD_GSK3_1	171	178	PF00069	0.701
MOD_GSK3_1	224	231	PF00069	0.741
MOD_GSK3_1	24	31	PF00069	0.642
MOD_GSK3_1	277	284	PF00069	0.752
MOD_GSK3_1	305	312	PF00069	0.732
MOD_GSK3_1	331	338	PF00069	0.758
MOD_GSK3_1	344	351	PF00069	0.639
MOD_GSK3_1	352	359	PF00069	0.659
MOD_GSK3_1	422	429	PF00069	0.729
MOD_GSK3_1	431	438	PF00069	0.576
MOD_GSK3_1	476	483	PF00069	0.618
MOD_GSK3_1	5	12	PF00069	0.688
MOD_GSK3_1	580	587	PF00069	0.666
MOD_GSK3_1	592	599	PF00069	0.581
MOD_GSK3_1	60	67	PF00069	0.777
MOD_GSK3_1	616	623	PF00069	0.734
MOD_GSK3_1	694	701	PF00069	0.746
MOD_GSK3_1	710	717	PF00069	0.594
MOD_GSK3_1	757	764	PF00069	0.677
MOD_GSK3_1	783	790	PF00069	0.686
MOD_GSK3_1	800	807	PF00069	0.724
MOD_GSK3_1	816	823	PF00069	0.598
MOD_GSK3_1	830	837	PF00069	0.568
MOD_GSK3_1	862	869	PF00069	0.630
MOD_GSK3_1	891	898	PF00069	0.717
MOD_LATS_1	513	519	PF00433	0.651
MOD_N-GLC_1	222	227	PF02516	0.698
MOD_N-GLC_1	351	356	PF02516	0.736
MOD_N-GLC_1	431	436	PF02516	0.729
MOD_N-GLC_1	67	72	PF02516	0.622
MOD_N-GLC_1	823	828	PF02516	0.677
MOD_N-GLC_2	73	75	PF02516	0.632
MOD_NEK2_1	224	229	PF00069	0.705
MOD_NEK2_1	292	297	PF00069	0.647
MOD_NEK2_1	426	431	PF00069	0.663
MOD_NEK2_1	480	485	PF00069	0.630
MOD_NEK2_1	563	568	PF00069	0.640
MOD_NEK2_1	569	574	PF00069	0.540
MOD_NEK2_1	584	589	PF00069	0.554
MOD_NEK2_1	648	653	PF00069	0.700
MOD_NEK2_1	816	821	PF00069	0.713
MOD_NEK2_1	830	835	PF00069	0.590
MOD_NEK2_1	862	867	PF00069	0.652
MOD_NEK2_2	234	239	PF00069	0.671
MOD_PIKK_1	480	486	PF00454	0.535
MOD_PIKK_1	629	635	PF00454	0.672
MOD_PIKK_1	736	742	PF00454	0.728
MOD_PIKK_1	804	810	PF00454	0.584
MOD_PIKK_1	864	870	PF00454	0.678
MOD_PIKK_1	902	908	PF00454	0.680
MOD_PK_1	134	140	PF00069	0.572
MOD_PK_1	362	368	PF00069	0.657
MOD_PKA_1	422	428	PF00069	0.726
MOD_PKA_1	460	466	PF00069	0.664
MOD_PKA_1	515	521	PF00069	0.639
MOD_PKA_2	229	235	PF00069	0.585
MOD_PKA_2	352	358	PF00069	0.734
MOD_PKA_2	421	427	PF00069	0.816
MOD_PKA_2	459	465	PF00069	0.593
MOD_PKA_2	515	521	PF00069	0.639
MOD_PKA_2	580	586	PF00069	0.736
MOD_PKA_2	661	667	PF00069	0.700
MOD_PKA_2	702	708	PF00069	0.777
MOD_PKA_2	777	783	PF00069	0.700
MOD_PKA_2	863	869	PF00069	0.638
MOD_PKB_1	577	585	PF00069	0.589
MOD_PKB_1	781	789	PF00069	0.578
MOD_Plk_1	431	437	PF00069	0.718
MOD_Plk_1	504	510	PF00069	0.621
MOD_Plk_1	606	612	PF00069	0.664
MOD_Plk_1	67	73	PF00069	0.621
MOD_Plk_1	823	829	PF00069	0.609
MOD_Plk_4	18	24	PF00069	0.642
MOD_Plk_4	234	240	PF00069	0.628
MOD_Plk_4	356	362	PF00069	0.744
MOD_Plk_4	476	482	PF00069	0.635
MOD_Plk_4	504	510	PF00069	0.692
MOD_Plk_4	563	569	PF00069	0.637
MOD_Plk_4	596	602	PF00069	0.700
MOD_Plk_4	869	875	PF00069	0.697
MOD_ProDKin_1	21	27	PF00069	0.747
MOD_ProDKin_1	213	219	PF00069	0.551
MOD_ProDKin_1	259	265	PF00069	0.644
MOD_ProDKin_1	28	34	PF00069	0.629
MOD_ProDKin_1	305	311	PF00069	0.746
MOD_ProDKin_1	312	318	PF00069	0.621
MOD_ProDKin_1	344	350	PF00069	0.705
MOD_ProDKin_1	391	397	PF00069	0.654
MOD_ProDKin_1	407	413	PF00069	0.571
MOD_ProDKin_1	5	11	PF00069	0.650
MOD_ProDKin_1	592	598	PF00069	0.659
MOD_ProDKin_1	601	607	PF00069	0.576
MOD_ProDKin_1	620	626	PF00069	0.709
MOD_ProDKin_1	631	637	PF00069	0.632
MOD_ProDKin_1	714	720	PF00069	0.682
MOD_ProDKin_1	784	790	PF00069	0.695
MOD_ProDKin_1	795	801	PF00069	0.608
MOD_SUMO_for_1	672	675	PF00179	0.706
MOD_SUMO_rev_2	280	289	PF00179	0.661
MOD_SUMO_rev_2	885	893	PF00179	0.618
TRG_DiLeu_BaEn_2	475	481	PF01217	0.622
TRG_DiLeu_BaLyEn_6	287	292	PF01217	0.680
TRG_DiLeu_BaLyEn_6	40	45	PF01217	0.742
TRG_ENDOCYTIC_2	485	488	PF00928	0.608
TRG_ER_diArg_1	114	117	PF00400	0.702
TRG_ER_diArg_1	415	417	PF00400	0.660
TRG_ER_diArg_1	536	539	PF00400	0.596
TRG_ER_diArg_1	576	579	PF00400	0.622
TRG_ER_diArg_1	702	704	PF00400	0.795
TRG_ER_diArg_1	743	745	PF00400	0.741
TRG_ER_diArg_1	927	929	PF00400	0.678
TRG_NLS_MonoCore_2	853	858	PF00514	0.540
TRG_NLS_MonoExtN_4	852	858	PF00514	0.538
TRG_Pf-PMV_PEXEL_1	42	47	PF00026	0.658
TRG_Pf-PMV_PEXEL_1	539	543	PF00026	0.612
TRG_Pf-PMV_PEXEL_1	722	727	PF00026	0.570

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGY8	Leishmania donovani	87%	100%
A4HAF9	Leishmania braziliensis	57%	99%
A4I9L5	Leishmania infantum	87%	100%
E9B4L3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%