Putative splicing factor ptsr1 interacting protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

splicing factor ptsr1 interacting protein, putative

Species:

Leishmania major

UniProt:

Q4Q3F8_LEIMA

TriTrypDb:

LmjF.34.0495 , LMJLV39_340010600 , LMJSD75_340010600

Length:

257

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q3F8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3F8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	203	207	PF00656	0.583
CLV_NRD_NRD_1	137	139	PF00675	0.830
CLV_NRD_NRD_1	152	154	PF00675	0.559
CLV_NRD_NRD_1	164	166	PF00675	0.573
CLV_NRD_NRD_1	173	175	PF00675	0.586
CLV_NRD_NRD_1	200	202	PF00675	0.618
CLV_NRD_NRD_1	211	213	PF00675	0.613
CLV_NRD_NRD_1	224	226	PF00675	0.661
CLV_NRD_NRD_1	227	229	PF00675	0.722
CLV_NRD_NRD_1	243	245	PF00675	0.520
CLV_NRD_NRD_1	250	252	PF00675	0.536
CLV_PCSK_FUR_1	162	166	PF00082	0.608
CLV_PCSK_FUR_1	197	201	PF00082	0.627
CLV_PCSK_FUR_1	225	229	PF00082	0.609
CLV_PCSK_KEX2_1	137	139	PF00082	0.830
CLV_PCSK_KEX2_1	152	154	PF00082	0.559
CLV_PCSK_KEX2_1	162	164	PF00082	0.571
CLV_PCSK_KEX2_1	173	175	PF00082	0.630
CLV_PCSK_KEX2_1	197	199	PF00082	0.630
CLV_PCSK_KEX2_1	200	202	PF00082	0.618
CLV_PCSK_KEX2_1	211	213	PF00082	0.613
CLV_PCSK_KEX2_1	224	226	PF00082	0.661
CLV_PCSK_KEX2_1	227	229	PF00082	0.722
CLV_PCSK_KEX2_1	243	245	PF00082	0.520
CLV_PCSK_KEX2_1	249	251	PF00082	0.527
CLV_PCSK_SKI1_1	42	46	PF00082	0.546
DEG_Nend_UBRbox_2	1	3	PF02207	0.575
DOC_MAPK_DCC_7	51	61	PF00069	0.665
DOC_PP4_MxPP_1	55	58	PF00568	0.660
DOC_USP7_MATH_1	69	73	PF00917	0.654
DOC_USP7_UBL2_3	86	90	PF12436	0.682
DOC_WW_Pin1_4	109	114	PF00397	0.699
LIG_14-3-3_CanoR_1	178	187	PF00244	0.636
LIG_14-3-3_CanoR_1	250	256	PF00244	0.506
LIG_deltaCOP1_diTrp_1	20	25	PF00928	0.402
LIG_FHA_2	110	116	PF00498	0.517
LIG_FHA_2	127	133	PF00498	0.528
LIG_FHA_2	92	98	PF00498	0.666
LIG_LIR_Gen_1	23	33	PF02991	0.405
LIG_LIR_Gen_1	95	106	PF02991	0.668
LIG_LIR_Nem_3	20	24	PF02991	0.412
LIG_LIR_Nem_3	40	44	PF02991	0.451
LIG_LIR_Nem_3	7	11	PF02991	0.605
LIG_LIR_Nem_3	95	101	PF02991	0.660
LIG_NRP_CendR_1	256	257	PF00754	0.608
LIG_Pex14_1	21	25	PF04695	0.396
LIG_SH2_CRK	41	45	PF00017	0.446
LIG_SH2_CRK	8	12	PF00017	0.604
LIG_SH2_NCK_1	8	12	PF00017	0.528
LIG_SH2_SRC	8	11	PF00017	0.608
LIG_SH2_STAT5	24	27	PF00017	0.410
LIG_SH3_3	50	56	PF00018	0.771
LIG_TRAF2_1	218	221	PF00917	0.686
LIG_WW_1	5	8	PF00397	0.525
LIG_WW_2	57	60	PF00397	0.678
MOD_CDK_SPK_2	109	114	PF00069	0.699
MOD_CK1_1	100	106	PF00069	0.623
MOD_CK1_1	108	114	PF00069	0.667
MOD_CK1_1	182	188	PF00069	0.688
MOD_CK1_1	190	196	PF00069	0.598
MOD_CK1_1	219	225	PF00069	0.699
MOD_CK1_1	232	238	PF00069	0.502
MOD_CK2_1	165	171	PF00069	0.692
MOD_CK2_1	215	221	PF00069	0.691
MOD_GlcNHglycan	107	110	PF01048	0.631
MOD_GlcNHglycan	192	195	PF01048	0.686
MOD_GlcNHglycan	231	234	PF01048	0.653
MOD_GlcNHglycan	71	74	PF01048	0.683
MOD_GSK3_1	104	111	PF00069	0.619
MOD_GSK3_1	133	140	PF00069	0.708
MOD_GSK3_1	178	185	PF00069	0.637
MOD_GSK3_1	189	196	PF00069	0.651
MOD_GSK3_1	211	218	PF00069	0.693
MOD_GSK3_1	227	234	PF00069	0.502
MOD_GSK3_1	61	68	PF00069	0.694
MOD_GSK3_1	96	103	PF00069	0.590
MOD_N-GLC_1	251	256	PF02516	0.510
MOD_NEK2_1	101	106	PF00069	0.601
MOD_PIKK_1	63	69	PF00454	0.702
MOD_PKA_1	137	143	PF00069	0.710
MOD_PKA_1	199	205	PF00069	0.615
MOD_PKA_1	211	217	PF00069	0.617
MOD_PKA_1	227	233	PF00069	0.503
MOD_PKA_2	133	139	PF00069	0.709
MOD_PKA_2	156	162	PF00069	0.686
MOD_PKA_2	182	188	PF00069	0.632
MOD_PKA_2	199	205	PF00069	0.649
MOD_PKA_2	210	216	PF00069	0.617
MOD_PKA_2	227	233	PF00069	0.492
MOD_PKB_1	163	171	PF00069	0.682
MOD_PKB_1	176	184	PF00069	0.562
MOD_PKB_1	197	205	PF00069	0.618
MOD_PKB_1	225	233	PF00069	0.673
MOD_PKB_1	249	257	PF00069	0.510
MOD_Plk_1	251	257	PF00069	0.519
MOD_Plk_1	96	102	PF00069	0.588
MOD_Plk_2-3	156	162	PF00069	0.686
MOD_Plk_4	97	103	PF00069	0.663
MOD_ProDKin_1	109	115	PF00069	0.701
MOD_SUMO_rev_2	82	88	PF00179	0.676
TRG_ENDOCYTIC_2	27	30	PF00928	0.506
TRG_ENDOCYTIC_2	41	44	PF00928	0.369
TRG_ENDOCYTIC_2	8	11	PF00928	0.608
TRG_ER_diArg_1	162	165	PF00400	0.575
TRG_ER_diArg_1	173	176	PF00400	0.625
TRG_ER_diArg_1	197	200	PF00400	0.629
TRG_ER_diArg_1	224	226	PF00400	0.613
TRG_ER_diArg_1	248	251	PF00400	0.520
TRG_ER_diArg_1	255	257	PF00400	0.596

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HR54	Leptomonas seymouri	45%	100%
A0A3Q8II79	Leishmania donovani	94%	100%
A4I9M0	Leishmania infantum	94%	100%
E9B4L8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%