Mitochondrial ATPase inhibitor

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q3E9_LEIMA

TriTrypDb:

LmjF.34.0580 , LMJLV39_340012000 , LMJSD75_340011700

Length:

122


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

Q4Q3E9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3E9


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	86	90	PF00656	0.563
CLV_NRD_NRD_1	11	13	PF00675	0.657
CLV_PCSK_KEX2_1	11	13	PF00082	0.644
CLV_PCSK_KEX2_1	77	79	PF00082	0.609
CLV_PCSK_KEX2_1	95	97	PF00082	0.622
CLV_PCSK_PC1ET2_1	77	79	PF00082	0.609
CLV_PCSK_PC1ET2_1	95	97	PF00082	0.622
CLV_PCSK_SKI1_1	12	16	PF00082	0.637
CLV_PCSK_SKI1_1	37	41	PF00082	0.576
DEG_Nend_UBRbox_3	1	3	PF02207	0.643
DOC_CKS1_1	60	65	PF01111	0.590
DOC_USP7_MATH_1	14	18	PF00917	0.578
DOC_USP7_UBL2_3	118	122	PF12436	0.616
DOC_USP7_UBL2_3	37	41	PF12436	0.622
DOC_USP7_UBL2_3	84	88	PF12436	0.544
DOC_WW_Pin1_4	59	64	PF00397	0.526
LIG_14-3-3_CanoR_1	11	19	PF00244	0.564
LIG_14-3-3_CanoR_1	29	35	PF00244	0.523
LIG_FHA_1	13	19	PF00498	0.657
LIG_FHA_2	60	66	PF00498	0.558
LIG_SH2_GRB2like	34	37	PF00017	0.631
LIG_SH2_SRC	67	70	PF00017	0.624
LIG_SH2_STAT5	34	37	PF00017	0.613
LIG_TRAF2_1	62	65	PF00917	0.508
MOD_CDK_SPxxK_3	59	66	PF00069	0.523
MOD_CK1_1	17	23	PF00069	0.635
MOD_CK2_1	58	64	PF00069	0.522
MOD_GlcNHglycan	108	112	PF01048	0.374
MOD_GlcNHglycan	19	22	PF01048	0.601
MOD_N-GLC_1	58	63	PF02516	0.639
MOD_PIKK_1	78	84	PF00454	0.614
MOD_PKA_2	28	34	PF00069	0.702
MOD_Plk_1	107	113	PF00069	0.378
MOD_Plk_4	14	20	PF00069	0.604
MOD_ProDKin_1	59	65	PF00069	0.524
MOD_SUMO_for_1	105	108	PF00179	0.622
MOD_SUMO_for_1	83	86	PF00179	0.623
TRG_ER_diArg_1	10	12	PF00400	0.661
TRG_Pf-PMV_PEXEL_1	41	45	PF00026	0.532
TRG_Pf-PMV_PEXEL_1	50	55	PF00026	0.523


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HXR7	Leptomonas seymouri	59%	97%
A0A1X0P8N6	Trypanosomatidae	38%	100%
A0A3Q8IUE6	Leishmania donovani	91%	100%
A0A3R7KP65	Trypanosoma rangeli	36%	100%
A4HAG8	Leishmania braziliensis	80%	100%
A4I9M8	Leishmania infantum	91%	100%
B6DTD2	Bodo saltans	30%	100%
D0A1Z3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
E9B4M7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
V5DIQ6	Trypanosoma cruzi	35%	100%