LeishMANIAdb
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Mitochondrial RNA binding complex 1 subunit

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Mitochondrial RNA binding complex 1 subunit
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q3D5_LEIMA
TriTrypDb:
LmjF.34.0710 * , LMJLV39_340013500 * , LMJSD75_340013500 *
Length:
769

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q3D5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q3D5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 583 587 PF00656 0.598
CLV_NRD_NRD_1 251 253 PF00675 0.596
CLV_NRD_NRD_1 351 353 PF00675 0.551
CLV_NRD_NRD_1 433 435 PF00675 0.591
CLV_NRD_NRD_1 463 465 PF00675 0.592
CLV_NRD_NRD_1 509 511 PF00675 0.623
CLV_PCSK_KEX2_1 177 179 PF00082 0.384
CLV_PCSK_KEX2_1 251 253 PF00082 0.596
CLV_PCSK_KEX2_1 351 353 PF00082 0.551
CLV_PCSK_KEX2_1 433 435 PF00082 0.521
CLV_PCSK_KEX2_1 509 511 PF00082 0.623
CLV_PCSK_KEX2_1 605 607 PF00082 0.490
CLV_PCSK_KEX2_1 693 695 PF00082 0.610
CLV_PCSK_KEX2_1 758 760 PF00082 0.710
CLV_PCSK_PC1ET2_1 177 179 PF00082 0.384
CLV_PCSK_PC1ET2_1 509 511 PF00082 0.623
CLV_PCSK_PC1ET2_1 605 607 PF00082 0.490
CLV_PCSK_PC1ET2_1 693 695 PF00082 0.610
CLV_PCSK_PC1ET2_1 758 760 PF00082 0.769
CLV_PCSK_SKI1_1 216 220 PF00082 0.560
CLV_PCSK_SKI1_1 313 317 PF00082 0.460
CLV_PCSK_SKI1_1 393 397 PF00082 0.601
CLV_PCSK_SKI1_1 413 417 PF00082 0.289
CLV_PCSK_SKI1_1 434 438 PF00082 0.520
CLV_PCSK_SKI1_1 465 469 PF00082 0.494
CLV_PCSK_SKI1_1 621 625 PF00082 0.625
CLV_PCSK_SKI1_1 676 680 PF00082 0.532
CLV_PCSK_SKI1_1 719 723 PF00082 0.600
DEG_APCC_DBOX_1 718 726 PF00400 0.595
DEG_SCF_FBW7_2 528 535 PF00400 0.527
DEG_SPOP_SBC_1 585 589 PF00917 0.598
DOC_CKS1_1 70 75 PF01111 0.572
DOC_CYCLIN_RxL_1 523 531 PF00134 0.587
DOC_CYCLIN_RxL_1 713 726 PF00134 0.597
DOC_MAPK_gen_1 433 443 PF00069 0.565
DOC_MAPK_gen_1 509 518 PF00069 0.614
DOC_MAPK_gen_1 564 572 PF00069 0.596
DOC_MAPK_gen_1 602 611 PF00069 0.382
DOC_MAPK_gen_1 742 751 PF00069 0.618
DOC_MAPK_MEF2A_6 605 613 PF00069 0.370
DOC_MAPK_RevD_3 418 434 PF00069 0.558
DOC_PP4_FxxP_1 94 97 PF00568 0.563
DOC_USP7_MATH_1 257 261 PF00917 0.663
DOC_USP7_MATH_1 314 318 PF00917 0.561
DOC_USP7_MATH_1 547 551 PF00917 0.611
DOC_USP7_MATH_1 632 636 PF00917 0.490
DOC_USP7_MATH_1 86 90 PF00917 0.579
DOC_USP7_UBL2_3 753 757 PF12436 0.723
DOC_WW_Pin1_4 284 289 PF00397 0.606
DOC_WW_Pin1_4 406 411 PF00397 0.578
DOC_WW_Pin1_4 509 514 PF00397 0.509
DOC_WW_Pin1_4 528 533 PF00397 0.475
DOC_WW_Pin1_4 56 61 PF00397 0.615
DOC_WW_Pin1_4 69 74 PF00397 0.401
DOC_WW_Pin1_4 729 734 PF00397 0.696
DOC_WW_Pin1_4 764 769 PF00397 0.639
LIG_14-3-3_CanoR_1 110 119 PF00244 0.524
LIG_14-3-3_CanoR_1 127 137 PF00244 0.380
LIG_14-3-3_CanoR_1 313 320 PF00244 0.455
LIG_14-3-3_CanoR_1 351 355 PF00244 0.555
LIG_14-3-3_CanoR_1 393 400 PF00244 0.637
LIG_14-3-3_CanoR_1 434 443 PF00244 0.565
LIG_14-3-3_CanoR_1 470 476 PF00244 0.571
LIG_14-3-3_CanoR_1 50 60 PF00244 0.434
LIG_14-3-3_CanoR_1 566 570 PF00244 0.473
LIG_14-3-3_CanoR_1 581 585 PF00244 0.428
LIG_14-3-3_CanoR_1 621 630 PF00244 0.583
LIG_14-3-3_CanoR_1 694 698 PF00244 0.533
LIG_14-3-3_CanoR_1 719 725 PF00244 0.532
LIG_14-3-3_CanoR_1 759 766 PF00244 0.766
LIG_Actin_WH2_2 153 170 PF00022 0.511
LIG_Actin_WH2_2 459 475 PF00022 0.530
LIG_APCC_ABBA_1 569 574 PF00400 0.560
LIG_BRCT_BRCA1_1 207 211 PF00533 0.527
LIG_deltaCOP1_diTrp_1 294 302 PF00928 0.550
LIG_FHA_1 13 19 PF00498 0.688
LIG_FHA_1 162 168 PF00498 0.474
LIG_FHA_1 218 224 PF00498 0.569
LIG_FHA_1 242 248 PF00498 0.490
LIG_FHA_1 25 31 PF00498 0.514
LIG_FHA_1 327 333 PF00498 0.560
LIG_FHA_1 337 343 PF00498 0.479
LIG_FHA_1 427 433 PF00498 0.503
LIG_FHA_1 513 519 PF00498 0.509
LIG_FHA_1 529 535 PF00498 0.572
LIG_FHA_1 587 593 PF00498 0.425
LIG_FHA_1 699 705 PF00498 0.452
LIG_FHA_1 70 76 PF00498 0.581
LIG_FHA_2 134 140 PF00498 0.471
LIG_FHA_2 220 226 PF00498 0.582
LIG_FHA_2 276 282 PF00498 0.507
LIG_FHA_2 285 291 PF00498 0.540
LIG_FHA_2 5 11 PF00498 0.530
LIG_FHA_2 586 592 PF00498 0.497
LIG_GBD_Chelix_1 75 83 PF00786 0.497
LIG_LIR_Apic_2 236 241 PF02991 0.385
LIG_LIR_Gen_1 208 219 PF02991 0.553
LIG_LIR_Gen_1 669 679 PF02991 0.478
LIG_LIR_Gen_1 701 708 PF02991 0.553
LIG_LIR_Gen_1 761 768 PF02991 0.765
LIG_LIR_Nem_3 136 140 PF02991 0.475
LIG_LIR_Nem_3 208 214 PF02991 0.581
LIG_LIR_Nem_3 669 674 PF02991 0.494
LIG_LIR_Nem_3 701 706 PF02991 0.555
LIG_LIR_Nem_3 761 766 PF02991 0.771
LIG_NRBOX 171 177 PF00104 0.496
LIG_NRBOX 660 666 PF00104 0.474
LIG_NRBOX 720 726 PF00104 0.595
LIG_PAM2_1 439 451 PF00658 0.531
LIG_PCNA_yPIPBox_3 150 158 PF02747 0.622
LIG_Pex14_1 703 707 PF04695 0.446
LIG_Pex14_2 94 98 PF04695 0.470
LIG_REV1ctd_RIR_1 299 308 PF16727 0.452
LIG_REV1ctd_RIR_1 676 684 PF16727 0.585
LIG_SH2_CRK 671 675 PF00017 0.465
LIG_SH2_NCK_1 671 675 PF00017 0.465
LIG_SH2_STAP1 66 70 PF00017 0.490
LIG_SH2_STAT3 369 372 PF00017 0.439
LIG_SH2_STAT5 238 241 PF00017 0.428
LIG_SH2_STAT5 369 372 PF00017 0.439
LIG_SH2_STAT5 448 451 PF00017 0.481
LIG_SH2_STAT5 707 710 PF00017 0.474
LIG_SH2_STAT5 740 743 PF00017 0.585
LIG_SH3_2 182 187 PF14604 0.412
LIG_SH3_3 179 185 PF00018 0.450
LIG_SUMO_SIM_anti_2 139 145 PF11976 0.602
LIG_SUMO_SIM_anti_2 338 345 PF11976 0.355
LIG_SUMO_SIM_anti_2 515 520 PF11976 0.363
LIG_SUMO_SIM_anti_2 550 559 PF11976 0.566
LIG_SUMO_SIM_anti_2 586 597 PF11976 0.481
LIG_SUMO_SIM_anti_2 720 728 PF11976 0.612
LIG_SUMO_SIM_par_1 338 345 PF11976 0.370
LIG_SUMO_SIM_par_1 550 559 PF11976 0.572
LIG_SUMO_SIM_par_1 586 597 PF11976 0.565
LIG_SUMO_SIM_par_1 720 728 PF11976 0.612
LIG_TRAF2_1 163 166 PF00917 0.560
LIG_TRAF2_1 303 306 PF00917 0.442
LIG_TRAF2_1 638 641 PF00917 0.495
LIG_UBA3_1 142 151 PF00899 0.560
LIG_UBA3_1 17 22 PF00899 0.706
LIG_UBA3_1 172 177 PF00899 0.366
LIG_UBA3_1 431 437 PF00899 0.559
LIG_WRC_WIRS_1 5 10 PF05994 0.529
LIG_WRC_WIRS_1 595 600 PF05994 0.569
MOD_CDK_SPK_2 406 411 PF00069 0.578
MOD_CDK_SPK_2 509 514 PF00069 0.565
MOD_CDK_SPxxK_3 406 413 PF00069 0.592
MOD_CK1_1 114 120 PF00069 0.557
MOD_CK1_1 129 135 PF00069 0.367
MOD_CK1_1 258 264 PF00069 0.605
MOD_CK1_1 300 306 PF00069 0.534
MOD_CK1_1 309 315 PF00069 0.446
MOD_CK1_1 31 37 PF00069 0.548
MOD_CK1_1 360 366 PF00069 0.480
MOD_CK1_1 474 480 PF00069 0.595
MOD_CK1_1 488 494 PF00069 0.335
MOD_CK1_1 54 60 PF00069 0.624
MOD_CK1_1 559 565 PF00069 0.538
MOD_CK1_1 587 593 PF00069 0.562
MOD_CK1_1 635 641 PF00069 0.560
MOD_CK1_1 669 675 PF00069 0.611
MOD_CK1_1 71 77 PF00069 0.427
MOD_CK1_1 720 726 PF00069 0.595
MOD_CK1_1 727 733 PF00069 0.580
MOD_CK1_1 761 767 PF00069 0.723
MOD_CK2_1 138 144 PF00069 0.590
MOD_CK2_1 159 165 PF00069 0.563
MOD_CK2_1 219 225 PF00069 0.576
MOD_CK2_1 260 266 PF00069 0.546
MOD_CK2_1 275 281 PF00069 0.405
MOD_CK2_1 300 306 PF00069 0.379
MOD_CK2_1 322 328 PF00069 0.607
MOD_CK2_1 37 43 PF00069 0.601
MOD_CK2_1 635 641 PF00069 0.602
MOD_Cter_Amidation 603 606 PF01082 0.464
MOD_DYRK1A_RPxSP_1 731 735 PF00069 0.697
MOD_GlcNHglycan 161 164 PF01048 0.513
MOD_GlcNHglycan 235 238 PF01048 0.608
MOD_GlcNHglycan 255 258 PF01048 0.509
MOD_GlcNHglycan 316 319 PF01048 0.613
MOD_GlcNHglycan 323 327 PF01048 0.586
MOD_GlcNHglycan 33 36 PF01048 0.646
MOD_GlcNHglycan 373 376 PF01048 0.600
MOD_GlcNHglycan 38 42 PF01048 0.593
MOD_GlcNHglycan 43 47 PF01048 0.537
MOD_GlcNHglycan 443 446 PF01048 0.580
MOD_GlcNHglycan 487 490 PF01048 0.470
MOD_GlcNHglycan 624 627 PF01048 0.607
MOD_GlcNHglycan 687 690 PF01048 0.571
MOD_GSK3_1 106 113 PF00069 0.603
MOD_GSK3_1 129 136 PF00069 0.543
MOD_GSK3_1 138 145 PF00069 0.599
MOD_GSK3_1 24 31 PF00069 0.530
MOD_GSK3_1 251 258 PF00069 0.668
MOD_GSK3_1 280 287 PF00069 0.563
MOD_GSK3_1 305 312 PF00069 0.484
MOD_GSK3_1 322 329 PF00069 0.514
MOD_GSK3_1 357 364 PF00069 0.538
MOD_GSK3_1 435 442 PF00069 0.638
MOD_GSK3_1 52 59 PF00069 0.530
MOD_GSK3_1 580 587 PF00069 0.600
MOD_GSK3_1 594 601 PF00069 0.341
MOD_GSK3_1 632 639 PF00069 0.558
MOD_GSK3_1 713 720 PF00069 0.597
MOD_GSK3_1 723 730 PF00069 0.482
MOD_GSK3_1 747 754 PF00069 0.607
MOD_N-GLC_1 205 210 PF02516 0.367
MOD_N-GLC_1 547 552 PF02516 0.603
MOD_N-GLC_1 698 703 PF02516 0.564
MOD_NEK2_1 106 111 PF00069 0.681
MOD_NEK2_1 12 17 PF00069 0.636
MOD_NEK2_1 126 131 PF00069 0.579
MOD_NEK2_1 138 143 PF00069 0.401
MOD_NEK2_1 217 222 PF00069 0.545
MOD_NEK2_1 280 285 PF00069 0.560
MOD_NEK2_1 297 302 PF00069 0.451
MOD_NEK2_1 336 341 PF00069 0.435
MOD_NEK2_1 37 42 PF00069 0.607
MOD_NEK2_1 371 376 PF00069 0.580
MOD_NEK2_1 441 446 PF00069 0.516
MOD_NEK2_1 485 490 PF00069 0.496
MOD_NEK2_1 52 57 PF00069 0.374
MOD_NEK2_1 539 544 PF00069 0.574
MOD_NEK2_1 558 563 PF00069 0.263
MOD_NEK2_1 584 589 PF00069 0.490
MOD_NEK2_1 594 599 PF00069 0.452
MOD_NEK2_1 724 729 PF00069 0.583
MOD_NEK2_2 747 752 PF00069 0.531
MOD_PIKK_1 111 117 PF00454 0.556
MOD_PIKK_1 280 286 PF00454 0.669
MOD_PIKK_1 357 363 PF00454 0.601
MOD_PIKK_1 435 441 PF00454 0.608
MOD_PIKK_1 636 642 PF00454 0.495
MOD_PIKK_1 725 731 PF00454 0.604
MOD_PK_1 713 719 PF00069 0.498
MOD_PKA_1 251 257 PF00069 0.613
MOD_PKA_1 693 699 PF00069 0.537
MOD_PKA_1 758 764 PF00069 0.754
MOD_PKA_2 126 132 PF00069 0.556
MOD_PKA_2 251 257 PF00069 0.675
MOD_PKA_2 350 356 PF00069 0.547
MOD_PKA_2 565 571 PF00069 0.530
MOD_PKA_2 580 586 PF00069 0.343
MOD_PKA_2 669 675 PF00069 0.611
MOD_PKA_2 693 699 PF00069 0.537
MOD_PKA_2 758 764 PF00069 0.711
MOD_Plk_1 12 18 PF00069 0.607
MOD_Plk_1 138 144 PF00069 0.571
MOD_Plk_1 224 230 PF00069 0.484
MOD_Plk_1 305 311 PF00069 0.560
MOD_Plk_1 357 363 PF00069 0.523
MOD_Plk_1 439 445 PF00069 0.607
MOD_Plk_1 656 662 PF00069 0.518
MOD_Plk_1 698 704 PF00069 0.539
MOD_Plk_1 713 719 PF00069 0.381
MOD_Plk_1 761 767 PF00069 0.769
MOD_Plk_2-3 286 292 PF00069 0.502
MOD_Plk_4 13 19 PF00069 0.717
MOD_Plk_4 133 139 PF00069 0.506
MOD_Plk_4 219 225 PF00069 0.498
MOD_Plk_4 297 303 PF00069 0.433
MOD_Plk_4 306 312 PF00069 0.420
MOD_Plk_4 426 432 PF00069 0.458
MOD_Plk_4 565 571 PF00069 0.439
MOD_Plk_4 693 699 PF00069 0.540
MOD_Plk_4 71 77 PF00069 0.408
MOD_Plk_4 720 726 PF00069 0.595
MOD_ProDKin_1 284 290 PF00069 0.597
MOD_ProDKin_1 406 412 PF00069 0.569
MOD_ProDKin_1 509 515 PF00069 0.505
MOD_ProDKin_1 528 534 PF00069 0.469
MOD_ProDKin_1 56 62 PF00069 0.612
MOD_ProDKin_1 69 75 PF00069 0.396
MOD_ProDKin_1 729 735 PF00069 0.695
MOD_SUMO_rev_2 144 153 PF00179 0.615
MOD_SUMO_rev_2 162 170 PF00179 0.317
TRG_DiLeu_BaEn_1 152 157 PF01217 0.568
TRG_DiLeu_BaEn_1 306 311 PF01217 0.507
TRG_DiLeu_BaEn_1 481 486 PF01217 0.563
TRG_DiLeu_BaEn_1 535 540 PF01217 0.590
TRG_DiLeu_BaEn_1 657 662 PF01217 0.522
TRG_DiLeu_BaLyEn_6 529 534 PF01217 0.530
TRG_DiLeu_BaLyEn_6 660 665 PF01217 0.465
TRG_ENDOCYTIC_2 671 674 PF00928 0.474
TRG_ER_diArg_1 276 279 PF00400 0.551
TRG_ER_diArg_1 350 352 PF00400 0.547
TRG_ER_diArg_1 432 434 PF00400 0.586
TRG_ER_FFAT_1 59 71 PF00635 0.601
TRG_NES_CRM1_1 139 152 PF08389 0.598
TRG_NES_CRM1_1 641 654 PF08389 0.482
TRG_NLS_MonoExtC_3 508 513 PF00514 0.613
TRG_NLS_MonoExtC_3 756 762 PF00514 0.703
TRG_NLS_MonoExtN_4 755 761 PF00514 0.758
TRG_Pf-PMV_PEXEL_1 110 115 PF00026 0.481
TRG_Pf-PMV_PEXEL_1 197 201 PF00026 0.592
TRG_Pf-PMV_PEXEL_1 503 507 PF00026 0.579

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3F0 Leptomonas seymouri 32% 84%
A0A3Q8IKR6 Leishmania donovani 94% 100%
A4HAI0 Leishmania braziliensis 82% 95%
A4IAP1 Leishmania infantum 94% 100%
E9B4P1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS