| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 1 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 4 |
| Forrest at al. (procyclic) | no | yes: 4 |
| Silverman et al. | no | yes: 2 |
| Pissara et al. | yes | yes: 24 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | yes | yes: 4 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 8 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 1, no: 22 |
| NetGPI | no | yes: 0, no: 23 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005829 | cytosol | 2 | 3 |
| GO:0005853 | eukaryotic translation elongation factor 1 complex | 2 | 24 |
| GO:0032991 | protein-containing complex | 1 | 24 |
| GO:0110165 | cellular anatomical entity | 1 | 3 |
| GO:0005737 | cytoplasm | 2 | 1 |
Related structures:
AlphaFold database: Q4Q3C1
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006414 | translational elongation | 5 | 3 |
| GO:0008152 | metabolic process | 1 | 3 |
| GO:0009058 | biosynthetic process | 2 | 3 |
| GO:0009059 | macromolecule biosynthetic process | 4 | 3 |
| GO:0009987 | cellular process | 1 | 3 |
| GO:0034645 | obsolete cellular macromolecule biosynthetic process | 4 | 3 |
| GO:0043170 | macromolecule metabolic process | 3 | 3 |
| GO:0044237 | cellular metabolic process | 2 | 3 |
| GO:0044249 | cellular biosynthetic process | 3 | 3 |
| GO:0044260 | obsolete cellular macromolecule metabolic process | 3 | 3 |
| GO:0071704 | organic substance metabolic process | 2 | 3 |
| GO:1901576 | organic substance biosynthetic process | 3 | 3 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | 3 | 24 |
| GO:0003746 | translation elongation factor activity | 4 | 24 |
| GO:0005085 | guanyl-nucleotide exchange factor activity | 3 | 3 |
| GO:0005488 | binding | 1 | 24 |
| GO:0008135 | translation factor activity, RNA binding | 3 | 24 |
| GO:0030234 | enzyme regulator activity | 2 | 3 |
| GO:0030695 | GTPase regulator activity | 4 | 3 |
| GO:0045182 | translation regulator activity | 1 | 24 |
| GO:0060589 | nucleoside-triphosphatase regulator activity | 3 | 3 |
| GO:0090079 | translation regulator activity, nucleic acid binding | 2 | 24 |
| GO:0097159 | organic cyclic compound binding | 2 | 24 |
| GO:0098772 | molecular function regulator activity | 1 | 3 |
| GO:0140677 | molecular function activator activity | 2 | 3 |
| GO:0140678 | molecular function inhibitor activity | 2 | 3 |
| GO:1901363 | heterocyclic compound binding | 2 | 24 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 61 | 63 | PF00675 | 0.562 |
| CLV_PCSK_KEX2_1 | 94 | 96 | PF00082 | 0.767 |
| CLV_PCSK_PC1ET2_1 | 94 | 96 | PF00082 | 0.767 |
| CLV_PCSK_SKI1_1 | 128 | 132 | PF00082 | 0.653 |
| CLV_PCSK_SKI1_1 | 134 | 138 | PF00082 | 0.638 |
| CLV_PCSK_SKI1_1 | 142 | 146 | PF00082 | 0.572 |
| CLV_PCSK_SKI1_1 | 20 | 24 | PF00082 | 0.533 |
| CLV_PCSK_SKI1_1 | 49 | 53 | PF00082 | 0.521 |
| DOC_CYCLIN_yCln2_LP_2 | 76 | 82 | PF00134 | 0.678 |
| DOC_MAPK_gen_1 | 197 | 205 | PF00069 | 0.368 |
| DOC_MAPK_MEF2A_6 | 70 | 78 | PF00069 | 0.670 |
| DOC_PP2B_LxvP_1 | 76 | 79 | PF13499 | 0.673 |
| DOC_USP7_MATH_1 | 150 | 154 | PF00917 | 0.444 |
| DOC_USP7_MATH_1 | 85 | 89 | PF00917 | 0.827 |
| DOC_USP7_UBL2_3 | 137 | 141 | PF12436 | 0.616 |
| DOC_USP7_UBL2_3 | 142 | 146 | PF12436 | 0.579 |
| DOC_USP7_UBL2_3 | 16 | 20 | PF12436 | 0.485 |
| DOC_USP7_UBL2_3 | 4 | 8 | PF12436 | 0.549 |
| LIG_APCC_ABBA_1 | 117 | 122 | PF00400 | 0.631 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.555 |
| LIG_BRCT_BRCA1_1 | 152 | 156 | PF00533 | 0.387 |
| LIG_Clathr_ClatBox_1 | 202 | 206 | PF01394 | 0.368 |
| LIG_FHA_1 | 162 | 168 | PF00498 | 0.367 |
| LIG_FHA_2 | 121 | 127 | PF00498 | 0.626 |
| LIG_FHA_2 | 27 | 33 | PF00498 | 0.581 |
| LIG_FHA_2 | 54 | 60 | PF00498 | 0.535 |
| LIG_SH2_SRC | 57 | 60 | PF00017 | 0.394 |
| LIG_SH3_3 | 100 | 106 | PF00018 | 0.749 |
| LIG_SH3_3 | 68 | 74 | PF00018 | 0.611 |
| LIG_SUMO_SIM_par_1 | 162 | 168 | PF11976 | 0.388 |
| LIG_SUMO_SIM_par_1 | 201 | 208 | PF11976 | 0.368 |
| LIG_TRAF2_1 | 110 | 113 | PF00917 | 0.753 |
| LIG_TRAF2_1 | 123 | 126 | PF00917 | 0.580 |
| LIG_UBA3_1 | 154 | 159 | PF00899 | 0.431 |
| LIG_UBA3_1 | 202 | 209 | PF00899 | 0.366 |
| MOD_CK1_1 | 15 | 21 | PF00069 | 0.556 |
| MOD_CK2_1 | 120 | 126 | PF00069 | 0.651 |
| MOD_CK2_1 | 53 | 59 | PF00069 | 0.526 |
| MOD_GlcNHglycan | 17 | 20 | PF01048 | 0.518 |
| MOD_GlcNHglycan | 210 | 213 | PF01048 | 0.387 |
| MOD_Plk_1 | 161 | 167 | PF00069 | 0.381 |
| MOD_Plk_2-3 | 225 | 231 | PF00069 | 0.399 |
| MOD_Plk_4 | 150 | 156 | PF00069 | 0.360 |
| MOD_SUMO_for_1 | 144 | 147 | PF00179 | 0.576 |
| MOD_SUMO_rev_2 | 12 | 18 | PF00179 | 0.478 |
| MOD_SUMO_rev_2 | 122 | 130 | PF00179 | 0.663 |
| MOD_SUMO_rev_2 | 138 | 144 | PF00179 | 0.520 |
| MOD_SUMO_rev_2 | 152 | 160 | PF00179 | 0.333 |
| MOD_SUMO_rev_2 | 180 | 190 | PF00179 | 0.368 |
| MOD_SUMO_rev_2 | 206 | 211 | PF00179 | 0.368 |
| MOD_SUMO_rev_2 | 31 | 36 | PF00179 | 0.384 |
| MOD_SUMO_rev_2 | 59 | 64 | PF00179 | 0.579 |
| TRG_DiLeu_BaEn_4 | 126 | 132 | PF01217 | 0.625 |
| TRG_NLS_MonoExtC_3 | 141 | 146 | PF00514 | 0.644 |
| TRG_NLS_MonoExtN_4 | 141 | 146 | PF00514 | 0.716 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P4W7 | Leptomonas seymouri | 63% | 100% |
| A0A0N1HZF7 | Leptomonas seymouri | 80% | 100% |
| A0A0S4JC29 | Bodo saltans | 56% | 100% |
| A0A0S4JK70 | Bodo saltans | 68% | 97% |
| A0A1X0P9D3 | Trypanosomatidae | 58% | 100% |
| A0A1X0PA37 | Trypanosomatidae | 71% | 100% |
| A0A3Q8IVV7 | Leishmania donovani | 70% | 100% |
| A0A3R7MFZ8 | Trypanosoma rangeli | 54% | 100% |
| A0A3S5H7W1 | Leishmania donovani | 95% | 99% |
| A0A422N8N9 | Trypanosoma rangeli | 71% | 100% |
| A4HAJ1 | Leishmania braziliensis | 81% | 100% |
| A4HAJ3 | Leishmania braziliensis | 80% | 77% |
| A4HAJ7 | Leishmania braziliensis | 81% | 99% |
| A4HP03 | Leishmania braziliensis | 64% | 100% |
| A4I9P1 | Leishmania infantum | 95% | 99% |
| A4IDB2 | Leishmania infantum | 69% | 100% |
| A5D989 | Bos taurus | 46% | 85% |
| C9ZN03 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 65% | 71% |
| D0A2X9 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 54% | 100% |
| E9ASR3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 68% | 100% |
| E9B4Q3 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 82% | 97% |
| E9B4Q5 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 82% | 74% |
| O74173 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 35% | 100% |
| O81918 | Beta vulgaris | 35% | 100% |
| O96827 | Drosophila melanogaster | 38% | 100% |
| P12262 | Artemia salina | 38% | 100% |
| P29522 | Bombyx mori | 36% | 100% |
| P29545 | Oryza sativa subsp. japonica | 39% | 100% |
| P29546 | Triticum aestivum | 33% | 100% |
| P30151 | Xenopus laevis | 41% | 100% |
| P34460 | Caenorhabditis elegans | 38% | 100% |
| P34826 | Oryctolagus cuniculus | 38% | 100% |
| P34827 | Trypanosoma cruzi | 66% | 100% |
| P48006 | Arabidopsis thaliana | 36% | 100% |
| P57776 | Mus musculus | 45% | 84% |
| P93447 | Spuriopimpinella brachycarpa | 36% | 100% |
| Q40680 | Oryza sativa subsp. japonica | 35% | 100% |
| Q40682 | Oryza sativa subsp. japonica | 34% | 100% |
| Q66NE2 | Leishmania major | 66% | 100% |
| Q68FR9 | Rattus norvegicus | 47% | 84% |
| Q69BZ7 | Penicillium citrinum | 32% | 100% |
| Q6DET9 | Xenopus tropicalis | 37% | 100% |
| Q717R8 | Ovis aries | 42% | 86% |
| Q84WM9 | Arabidopsis thaliana | 35% | 100% |
| Q9GRF8 | Dictyostelium discoideum | 37% | 100% |
| Q9SI20 | Arabidopsis thaliana | 36% | 100% |