Enriched_in_surface-labeled_proteome_protein_-_putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Enriched in surface-labeled proteome protein 11, putative

Species:

Leishmania major

UniProt:

Q4Q386_LEIMA

TriTrypDb:

LmjF.34.1175 , LMJLV39_340019700 , LMJSD75_340019700

Length:

258

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 4, no: 1
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0020016	ciliary pocket	2	2
GO:0110165	cellular anatomical entity	1	5

Expansion

Sequence features

Q4Q386

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q386

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	10	12	PF00675	0.441
CLV_NRD_NRD_1	13	15	PF00675	0.260
CLV_NRD_NRD_1	174	176	PF00675	0.490
CLV_PCSK_FUR_1	11	15	PF00082	0.398
CLV_PCSK_KEX2_1	10	12	PF00082	0.441
CLV_PCSK_KEX2_1	13	15	PF00082	0.260
CLV_PCSK_KEX2_1	174	176	PF00082	0.490
CLV_PCSK_SKI1_1	111	115	PF00082	0.577
CLV_PCSK_SKI1_1	168	172	PF00082	0.462
DOC_CKS1_1	222	227	PF01111	0.716
DOC_PP2B_LxvP_1	78	81	PF13499	0.422
DOC_USP7_MATH_1	250	254	PF00917	0.678
DOC_WW_Pin1_4	162	167	PF00397	0.641
DOC_WW_Pin1_4	216	221	PF00397	0.737
LIG_14-3-3_CanoR_1	11	21	PF00244	0.512
LIG_14-3-3_CanoR_1	210	217	PF00244	0.639
LIG_14-3-3_CanoR_1	51	60	PF00244	0.435
LIG_14-3-3_CanoR_1	61	69	PF00244	0.328
LIG_AP2alpha_2	115	117	PF02296	0.427
LIG_BIR_II_1	1	5	PF00653	0.696
LIG_BRCT_BRCA1_1	196	200	PF00533	0.677
LIG_FHA_1	16	22	PF00498	0.356
LIG_FHA_1	167	173	PF00498	0.714
LIG_FHA_1	222	228	PF00498	0.733
LIG_FHA_1	250	256	PF00498	0.658
LIG_FHA_2	199	205	PF00498	0.693
LIG_LIR_Gen_1	133	143	PF02991	0.269
LIG_LIR_Nem_3	133	138	PF02991	0.298
LIG_LIR_Nem_3	145	150	PF02991	0.338
LIG_LIR_Nem_3	162	167	PF02991	0.644
LIG_MYND_1	112	116	PF01753	0.398
LIG_NRBOX	24	30	PF00104	0.376
LIG_Pex14_1	160	164	PF04695	0.682
LIG_PTB_Apo_2	84	91	PF02174	0.432
LIG_PTB_Phospho_1	84	90	PF10480	0.436
LIG_SH2_CRK	164	168	PF00017	0.656
LIG_SH2_GRB2like	85	88	PF00017	0.449
LIG_SH2_NCK_1	195	199	PF00017	0.680
LIG_SH2_SRC	85	88	PF00017	0.449
LIG_SH2_STAT5	151	154	PF00017	0.405
LIG_SH2_STAT5	164	167	PF00017	0.593
LIG_SH2_STAT5	85	88	PF00017	0.449
LIG_SH2_STAT5	90	93	PF00017	0.366
LIG_SH3_1	180	186	PF00018	0.601
LIG_SH3_3	176	182	PF00018	0.739
LIG_SH3_3	211	217	PF00018	0.684
LIG_SH3_3	219	225	PF00018	0.748
LIG_SH3_3	252	258	PF00018	0.697
LIG_SH3_3	46	52	PF00018	0.474
MOD_CDK_SPxK_1	162	168	PF00069	0.586
MOD_CK1_1	142	148	PF00069	0.515
MOD_CK1_1	212	218	PF00069	0.768
MOD_CK1_1	38	44	PF00069	0.582
MOD_CK1_1	50	56	PF00069	0.418
MOD_CK2_1	198	204	PF00069	0.698
MOD_CK2_1	235	241	PF00069	0.755
MOD_GlcNHglycan	1	4	PF01048	0.580
MOD_GlcNHglycan	141	144	PF01048	0.375
MOD_GlcNHglycan	196	199	PF01048	0.536
MOD_GlcNHglycan	211	214	PF01048	0.468
MOD_GlcNHglycan	252	255	PF01048	0.496
MOD_GlcNHglycan	54	57	PF01048	0.602
MOD_GlcNHglycan	94	97	PF01048	0.658
MOD_GSK3_1	126	133	PF00069	0.401
MOD_GSK3_1	162	169	PF00069	0.680
MOD_GSK3_1	194	201	PF00069	0.646
MOD_GSK3_1	212	219	PF00069	0.607
MOD_GSK3_1	35	42	PF00069	0.592
MOD_N-GLC_1	35	40	PF02516	0.677
MOD_NEK2_1	209	214	PF00069	0.713
MOD_NEK2_1	23	28	PF00069	0.461
MOD_NEK2_2	130	135	PF00069	0.243
MOD_OFUCOSY	104	110	PF10250	0.646
MOD_OFUCOSY	127	134	PF10250	0.526
MOD_PIKK_1	55	61	PF00454	0.424
MOD_PKA_1	13	19	PF00069	0.460
MOD_PKA_2	12	18	PF00069	0.509
MOD_PKA_2	209	215	PF00069	0.636
MOD_PKA_2	47	53	PF00069	0.490
MOD_PKB_1	11	19	PF00069	0.460
MOD_Plk_4	126	132	PF00069	0.431
MOD_Plk_4	23	29	PF00069	0.308
MOD_Plk_4	80	86	PF00069	0.453
MOD_ProDKin_1	162	168	PF00069	0.642
MOD_ProDKin_1	216	222	PF00069	0.740
MOD_SUMO_rev_2	38	46	PF00179	0.487
TRG_ENDOCYTIC_2	164	167	PF00928	0.693
TRG_ER_diArg_1	100	103	PF00400	0.394
TRG_ER_diArg_1	173	175	PF00400	0.695
TRG_ER_diArg_1	9	11	PF00400	0.600
TRG_Pf-PMV_PEXEL_1	185	189	PF00026	0.507

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X7R5	Leishmania donovani	90%	93%
A4HAN6	Leishmania braziliensis	62%	100%
A4I9S9	Leishmania infantum	91%	93%
E9B4U0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	93%