LeishMANIAdb
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ATP-dependent RNA helicase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP-dependent RNA helicase-like protein
Gene product:
ATP-dependent RNA helicase-like protein
Species:
Leishmania major
UniProt:
Q4Q384_LEIMA
TriTrypDb:
LmjF.34.1190 * , LMJLV39_340019900 * , LMJSD75_340019900 *
Length:
1531

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 19
NetGPI no yes: 0, no: 19
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 3
GO:0005739 mitochondrion 5 3
GO:0020023 kinetoplast 2 3
GO:0031974 membrane-enclosed lumen 2 3
GO:0031981 nuclear lumen 5 3
GO:0032838 plasma membrane bounded cell projection cytoplasm 4 3
GO:0043226 organelle 2 3
GO:0043227 membrane-bounded organelle 3 3
GO:0043229 intracellular organelle 3 3
GO:0043231 intracellular membrane-bounded organelle 4 3
GO:0043233 organelle lumen 3 3
GO:0070013 intracellular organelle lumen 4 3
GO:0097014 ciliary plasm 5 3
GO:0099568 cytoplasmic region 3 3
GO:0110165 cellular anatomical entity 1 3
GO:0031019 mitochondrial mRNA editing complex 3 1
GO:0032991 protein-containing complex 1 1
GO:0045293 mRNA editing complex 3 1
GO:0098798 mitochondrial protein-containing complex 2 1
GO:1902494 catalytic complex 2 1

Expansion

Sequence features

Q4Q384
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0008152 metabolic process 1 1
GO:0009451 RNA modification 5 1
GO:0009892 negative regulation of metabolic process 4 1
GO:0009893 positive regulation of metabolic process 4 1
GO:0009894 regulation of catabolic process 4 1
GO:0009895 negative regulation of catabolic process 5 1
GO:0009987 cellular process 1 1
GO:0010468 regulation of gene expression 5 1
GO:0010604 positive regulation of macromolecule metabolic process 5 1
GO:0010605 negative regulation of macromolecule metabolic process 5 1
GO:0010608 post-transcriptional regulation of gene expression 6 1
GO:0010628 positive regulation of gene expression 6 1
GO:0016070 RNA metabolic process 5 1
GO:0016071 mRNA metabolic process 6 1
GO:0016553 base conversion or substitution editing 6 1
GO:0016554 cytidine to uridine editing 7 1
GO:0016556 mRNA modification 6 1
GO:0019219 regulation of nucleobase-containing compound metabolic process 5 1
GO:0019222 regulation of metabolic process 3 1
GO:0031323 regulation of cellular metabolic process 4 1
GO:0031324 negative regulation of cellular metabolic process 5 1
GO:0031329 regulation of cellular catabolic process 5 1
GO:0031330 negative regulation of cellular catabolic process 6 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0043170 macromolecule metabolic process 3 1
GO:0043412 macromolecule modification 4 1
GO:0043487 regulation of RNA stability 3 1
GO:0043488 regulation of mRNA stability 4 1
GO:0043489 RNA stabilization 4 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 6 1
GO:0046483 heterocycle metabolic process 3 1
GO:0048255 mRNA stabilization 5 1
GO:0048518 positive regulation of biological process 3 1
GO:0048519 negative regulation of biological process 3 1
GO:0048523 negative regulation of cellular process 4 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0051171 regulation of nitrogen compound metabolic process 4 1
GO:0051172 negative regulation of nitrogen compound metabolic process 5 1
GO:0051252 regulation of RNA metabolic process 5 1
GO:0051253 negative regulation of RNA metabolic process 6 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0061013 regulation of mRNA catabolic process 6 1
GO:0065007 biological regulation 1 1
GO:0065008 regulation of biological quality 2 1
GO:0071704 organic substance metabolic process 2 1
GO:0080090 regulation of primary metabolic process 4 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:1902369 negative regulation of RNA catabolic process 7 1
GO:1902373 negative regulation of mRNA catabolic process 7 1
GO:1903311 regulation of mRNA metabolic process 6 1
GO:1903312 negative regulation of mRNA metabolic process 7 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 20
GO:0003676 nucleic acid binding 3 20
GO:0003723 RNA binding 4 11
GO:0003824 catalytic activity 1 20
GO:0004386 helicase activity 2 20
GO:0005488 binding 1 20
GO:0005524 ATP binding 5 20
GO:0016787 hydrolase activity 2 13
GO:0017076 purine nucleotide binding 4 20
GO:0030554 adenyl nucleotide binding 5 20
GO:0032553 ribonucleotide binding 3 20
GO:0032555 purine ribonucleotide binding 4 20
GO:0032559 adenyl ribonucleotide binding 5 20
GO:0035639 purine ribonucleoside triphosphate binding 4 20
GO:0036094 small molecule binding 2 20
GO:0043167 ion binding 2 20
GO:0043168 anion binding 3 20
GO:0097159 organic cyclic compound binding 2 20
GO:0097367 carbohydrate derivative binding 2 20
GO:0140640 catalytic activity, acting on a nucleic acid 2 20
GO:0140657 ATP-dependent activity 1 20
GO:1901265 nucleoside phosphate binding 3 20
GO:1901363 heterocyclic compound binding 2 20
GO:0003724 RNA helicase activity 3 1
GO:0003729 mRNA binding 5 1
GO:0008186 ATP-dependent activity, acting on RNA 2 1
GO:0034458 3'-5' RNA helicase activity 4 1
GO:0140098 catalytic activity, acting on RNA 3 1
GO:0008270 zinc ion binding 6 3
GO:0043169 cation binding 3 3
GO:0046872 metal ion binding 4 3
GO:0046914 transition metal ion binding 5 3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1147 1151 PF00656 0.620
CLV_C14_Caspase3-7 1185 1189 PF00656 0.453
CLV_C14_Caspase3-7 123 127 PF00656 0.496
CLV_C14_Caspase3-7 1283 1287 PF00656 0.351
CLV_C14_Caspase3-7 183 187 PF00656 0.438
CLV_C14_Caspase3-7 430 434 PF00656 0.649
CLV_C14_Caspase3-7 806 810 PF00656 0.450
CLV_C14_Caspase3-7 996 1000 PF00656 0.392
CLV_NRD_NRD_1 1071 1073 PF00675 0.432
CLV_NRD_NRD_1 1256 1258 PF00675 0.566
CLV_NRD_NRD_1 1278 1280 PF00675 0.456
CLV_NRD_NRD_1 1299 1301 PF00675 0.378
CLV_NRD_NRD_1 1424 1426 PF00675 0.437
CLV_NRD_NRD_1 1471 1473 PF00675 0.395
CLV_NRD_NRD_1 165 167 PF00675 0.557
CLV_NRD_NRD_1 258 260 PF00675 0.519
CLV_NRD_NRD_1 290 292 PF00675 0.580
CLV_NRD_NRD_1 476 478 PF00675 0.531
CLV_NRD_NRD_1 488 490 PF00675 0.416
CLV_NRD_NRD_1 550 552 PF00675 0.274
CLV_NRD_NRD_1 734 736 PF00675 0.529
CLV_NRD_NRD_1 929 931 PF00675 0.250
CLV_NRD_NRD_1 963 965 PF00675 0.491
CLV_PCSK_FUR_1 1072 1076 PF00082 0.365
CLV_PCSK_FUR_1 255 259 PF00082 0.499
CLV_PCSK_KEX2_1 1074 1076 PF00082 0.423
CLV_PCSK_KEX2_1 1278 1280 PF00082 0.456
CLV_PCSK_KEX2_1 1299 1301 PF00082 0.378
CLV_PCSK_KEX2_1 1424 1426 PF00082 0.441
CLV_PCSK_KEX2_1 1471 1473 PF00082 0.441
CLV_PCSK_KEX2_1 165 167 PF00082 0.557
CLV_PCSK_KEX2_1 226 228 PF00082 0.468
CLV_PCSK_KEX2_1 257 259 PF00082 0.521
CLV_PCSK_KEX2_1 366 368 PF00082 0.322
CLV_PCSK_KEX2_1 476 478 PF00082 0.510
CLV_PCSK_KEX2_1 488 490 PF00082 0.327
CLV_PCSK_KEX2_1 550 552 PF00082 0.275
CLV_PCSK_KEX2_1 734 736 PF00082 0.529
CLV_PCSK_KEX2_1 963 965 PF00082 0.246
CLV_PCSK_PC1ET2_1 1074 1076 PF00082 0.448
CLV_PCSK_PC1ET2_1 226 228 PF00082 0.582
CLV_PCSK_PC1ET2_1 366 368 PF00082 0.322
CLV_PCSK_PC7_1 730 736 PF00082 0.265
CLV_PCSK_SKI1_1 1035 1039 PF00082 0.280
CLV_PCSK_SKI1_1 1075 1079 PF00082 0.444
CLV_PCSK_SKI1_1 1127 1131 PF00082 0.334
CLV_PCSK_SKI1_1 1270 1274 PF00082 0.498
CLV_PCSK_SKI1_1 1303 1307 PF00082 0.580
CLV_PCSK_SKI1_1 1424 1428 PF00082 0.402
CLV_PCSK_SKI1_1 198 202 PF00082 0.513
CLV_PCSK_SKI1_1 223 227 PF00082 0.479
CLV_PCSK_SKI1_1 32 36 PF00082 0.421
CLV_PCSK_SKI1_1 404 408 PF00082 0.637
CLV_PCSK_SKI1_1 448 452 PF00082 0.540
CLV_PCSK_SKI1_1 51 55 PF00082 0.638
CLV_PCSK_SKI1_1 585 589 PF00082 0.276
CLV_PCSK_SKI1_1 60 64 PF00082 0.371
CLV_PCSK_SKI1_1 631 635 PF00082 0.265
CLV_PCSK_SKI1_1 641 645 PF00082 0.289
CLV_PCSK_SKI1_1 735 739 PF00082 0.440
CLV_PCSK_SKI1_1 764 768 PF00082 0.253
CLV_PCSK_SKI1_1 774 778 PF00082 0.262
CLV_PCSK_SKI1_1 826 830 PF00082 0.277
CLV_PCSK_SKI1_1 944 948 PF00082 0.452
CLV_Separin_Metazoa 1003 1007 PF03568 0.436
CLV_Separin_Metazoa 148 152 PF03568 0.697
CLV_Separin_Metazoa 162 166 PF03568 0.501
DEG_APCC_DBOX_1 330 338 PF00400 0.412
DEG_APCC_DBOX_1 963 971 PF00400 0.368
DEG_Nend_Nbox_1 1 3 PF02207 0.507
DEG_ODPH_VHL_1 954 967 PF01847 0.260
DEG_SCF_FBW7_1 306 311 PF00400 0.416
DEG_SCF_FBW7_1 907 914 PF00400 0.495
DEG_SCF_FBW7_2 1017 1022 PF00400 0.536
DEG_SCF_SKP2-CKS1_1 710 717 PF00560 0.504
DEG_SPOP_SBC_1 1310 1314 PF00917 0.463
DEG_SPOP_SBC_1 875 879 PF00917 0.420
DOC_ANK_TNKS_1 246 253 PF00023 0.468
DOC_CDC14_PxL_1 1426 1434 PF14671 0.346
DOC_CKS1_1 110 115 PF01111 0.677
DOC_CKS1_1 908 913 PF01111 0.392
DOC_CYCLIN_RxL_1 1072 1082 PF00134 0.412
DOC_CYCLIN_RxL_1 60 74 PF00134 0.512
DOC_CYCLIN_RxL_1 628 635 PF00134 0.458
DOC_MAPK_gen_1 1252 1261 PF00069 0.546
DOC_MAPK_gen_1 30 39 PF00069 0.378
DOC_MAPK_gen_1 476 482 PF00069 0.504
DOC_MAPK_gen_1 60 70 PF00069 0.515
DOC_MAPK_gen_1 636 644 PF00069 0.496
DOC_MAPK_gen_1 734 740 PF00069 0.388
DOC_MAPK_gen_1 963 970 PF00069 0.238
DOC_MAPK_HePTP_8 1422 1434 PF00069 0.346
DOC_MAPK_MEF2A_6 1425 1434 PF00069 0.350
DOC_MAPK_MEF2A_6 30 39 PF00069 0.555
DOC_MAPK_MEF2A_6 636 644 PF00069 0.477
DOC_MAPK_MEF2A_6 963 972 PF00069 0.311
DOC_MAPK_NFAT4_5 32 40 PF00069 0.550
DOC_PP1_RVXF_1 64 71 PF00149 0.538
DOC_PP2B_LxvP_1 1240 1243 PF13499 0.524
DOC_PP2B_LxvP_1 1427 1430 PF13499 0.491
DOC_PP2B_LxvP_1 35 38 PF13499 0.515
DOC_PP2B_LxvP_1 990 993 PF13499 0.585
DOC_PP4_FxxP_1 15 18 PF00568 0.533
DOC_PP4_FxxP_1 691 694 PF00568 0.478
DOC_PP4_FxxP_1 989 992 PF00568 0.463
DOC_SPAK_OSR1_1 798 802 PF12202 0.396
DOC_USP7_MATH_1 1182 1186 PF00917 0.596
DOC_USP7_MATH_1 1246 1250 PF00917 0.581
DOC_USP7_MATH_1 1272 1276 PF00917 0.376
DOC_USP7_MATH_1 1310 1314 PF00917 0.463
DOC_USP7_MATH_1 1357 1361 PF00917 0.441
DOC_USP7_MATH_1 18 22 PF00917 0.513
DOC_USP7_MATH_1 278 282 PF00917 0.588
DOC_USP7_MATH_1 377 381 PF00917 0.500
DOC_USP7_MATH_1 487 491 PF00917 0.452
DOC_USP7_MATH_1 606 610 PF00917 0.382
DOC_USP7_MATH_1 698 702 PF00917 0.568
DOC_USP7_MATH_1 715 719 PF00917 0.583
DOC_USP7_MATH_1 794 798 PF00917 0.448
DOC_USP7_MATH_1 819 823 PF00917 0.436
DOC_USP7_MATH_1 87 91 PF00917 0.500
DOC_USP7_MATH_1 875 879 PF00917 0.567
DOC_USP7_UBL2_3 713 717 PF12436 0.500
DOC_WW_Pin1_4 1015 1020 PF00397 0.455
DOC_WW_Pin1_4 109 114 PF00397 0.602
DOC_WW_Pin1_4 1134 1139 PF00397 0.574
DOC_WW_Pin1_4 1312 1317 PF00397 0.571
DOC_WW_Pin1_4 1436 1441 PF00397 0.471
DOC_WW_Pin1_4 1450 1455 PF00397 0.578
DOC_WW_Pin1_4 304 309 PF00397 0.458
DOC_WW_Pin1_4 379 384 PF00397 0.597
DOC_WW_Pin1_4 659 664 PF00397 0.448
DOC_WW_Pin1_4 690 695 PF00397 0.432
DOC_WW_Pin1_4 711 716 PF00397 0.684
DOC_WW_Pin1_4 721 726 PF00397 0.543
DOC_WW_Pin1_4 83 88 PF00397 0.641
DOC_WW_Pin1_4 878 883 PF00397 0.577
DOC_WW_Pin1_4 907 912 PF00397 0.585
DOC_WW_Pin1_4 92 97 PF00397 0.563
LIG_14-3-3_CanoR_1 1217 1221 PF00244 0.503
LIG_14-3-3_CanoR_1 1383 1387 PF00244 0.387
LIG_14-3-3_CanoR_1 1393 1397 PF00244 0.330
LIG_14-3-3_CanoR_1 1411 1419 PF00244 0.557
LIG_14-3-3_CanoR_1 329 335 PF00244 0.528
LIG_14-3-3_CanoR_1 452 460 PF00244 0.454
LIG_14-3-3_CanoR_1 488 493 PF00244 0.386
LIG_14-3-3_CanoR_1 550 557 PF00244 0.476
LIG_14-3-3_CanoR_1 565 570 PF00244 0.478
LIG_14-3-3_CanoR_1 585 590 PF00244 0.469
LIG_14-3-3_CanoR_1 860 866 PF00244 0.524
LIG_14-3-3_CanoR_1 933 943 PF00244 0.544
LIG_Actin_WH2_2 1101 1119 PF00022 0.456
LIG_Actin_WH2_2 1456 1473 PF00022 0.395
LIG_Actin_WH2_2 18 34 PF00022 0.467
LIG_Actin_WH2_2 388 406 PF00022 0.557
LIG_Actin_WH2_2 626 643 PF00022 0.496
LIG_AP2alpha_1 1327 1331 PF02296 0.439
LIG_APCC_ABBA_1 1324 1329 PF00400 0.445
LIG_APCC_ABBA_1 1377 1382 PF00400 0.306
LIG_APCC_ABBA_1 954 959 PF00400 0.319
LIG_BIR_III_2 1286 1290 PF00653 0.351
LIG_BIR_III_2 1503 1507 PF00653 0.513
LIG_BRCT_BRCA1_1 692 696 PF00533 0.344
LIG_BRCT_BRCA1_1 880 884 PF00533 0.421
LIG_CaM_IQ_9 925 940 PF13499 0.441
LIG_CaM_NSCaTE_8 1350 1357 PF13499 0.400
LIG_Clathr_ClatBox_1 1489 1493 PF01394 0.479
LIG_deltaCOP1_diTrp_1 949 957 PF00928 0.331
LIG_FHA_1 1179 1185 PF00498 0.376
LIG_FHA_1 1205 1211 PF00498 0.556
LIG_FHA_1 1383 1389 PF00498 0.407
LIG_FHA_1 159 165 PF00498 0.608
LIG_FHA_1 197 203 PF00498 0.410
LIG_FHA_1 520 526 PF00498 0.473
LIG_FHA_1 589 595 PF00498 0.476
LIG_FHA_1 660 666 PF00498 0.422
LIG_FHA_1 714 720 PF00498 0.666
LIG_FHA_1 822 828 PF00498 0.437
LIG_FHA_1 847 853 PF00498 0.432
LIG_FHA_1 907 913 PF00498 0.419
LIG_FHA_1 945 951 PF00498 0.382
LIG_FHA_2 1061 1067 PF00498 0.429
LIG_FHA_2 1167 1173 PF00498 0.483
LIG_FHA_2 1312 1318 PF00498 0.387
LIG_FHA_2 143 149 PF00498 0.553
LIG_FHA_2 417 423 PF00498 0.690
LIG_FHA_2 599 605 PF00498 0.453
LIG_FHA_2 837 843 PF00498 0.474
LIG_FHA_2 853 859 PF00498 0.474
LIG_FHA_2 986 992 PF00498 0.586
LIG_FHA_2 994 1000 PF00498 0.523
LIG_GBD_Chelix_1 1388 1396 PF00786 0.439
LIG_GBD_Chelix_1 395 403 PF00786 0.566
LIG_Integrin_isoDGR_2 40 42 PF01839 0.382
LIG_Integrin_RGD_1 1284 1286 PF01839 0.391
LIG_LIR_Apic_2 12 18 PF02991 0.782
LIG_LIR_Apic_2 688 694 PF02991 0.467
LIG_LIR_Apic_2 785 789 PF02991 0.557
LIG_LIR_Apic_2 988 992 PF02991 0.515
LIG_LIR_Gen_1 1022 1031 PF02991 0.442
LIG_LIR_Gen_1 1103 1111 PF02991 0.425
LIG_LIR_Gen_1 1263 1272 PF02991 0.557
LIG_LIR_Gen_1 1348 1357 PF02991 0.318
LIG_LIR_Gen_1 1374 1384 PF02991 0.351
LIG_LIR_Gen_1 1385 1392 PF02991 0.325
LIG_LIR_Gen_1 1395 1404 PF02991 0.452
LIG_LIR_Gen_1 1453 1463 PF02991 0.632
LIG_LIR_Gen_1 741 749 PF02991 0.258
LIG_LIR_Gen_1 796 804 PF02991 0.424
LIG_LIR_Gen_1 881 892 PF02991 0.421
LIG_LIR_Gen_1 949 958 PF02991 0.391
LIG_LIR_LC3C_4 394 397 PF02991 0.380
LIG_LIR_Nem_3 1022 1026 PF02991 0.442
LIG_LIR_Nem_3 1103 1108 PF02991 0.466
LIG_LIR_Nem_3 120 124 PF02991 0.466
LIG_LIR_Nem_3 1263 1269 PF02991 0.566
LIG_LIR_Nem_3 1348 1353 PF02991 0.312
LIG_LIR_Nem_3 1374 1379 PF02991 0.360
LIG_LIR_Nem_3 1385 1389 PF02991 0.305
LIG_LIR_Nem_3 1395 1400 PF02991 0.417
LIG_LIR_Nem_3 1453 1458 PF02991 0.646
LIG_LIR_Nem_3 652 657 PF02991 0.507
LIG_LIR_Nem_3 693 699 PF02991 0.418
LIG_LIR_Nem_3 741 745 PF02991 0.291
LIG_LIR_Nem_3 796 802 PF02991 0.481
LIG_LIR_Nem_3 881 887 PF02991 0.525
LIG_LIR_Nem_3 949 954 PF02991 0.407
LIG_NRBOX 1348 1354 PF00104 0.296
LIG_NRBOX 970 976 PF00104 0.333
LIG_NRP_CendR_1 1529 1531 PF00754 0.520
LIG_Pex14_2 1327 1331 PF04695 0.439
LIG_Pex14_2 654 658 PF04695 0.374
LIG_Pex14_2 769 773 PF04695 0.450
LIG_PTAP_UEV_1 274 279 PF05743 0.492
LIG_SH2_CRK 1386 1390 PF00017 0.408
LIG_SH2_CRK 171 175 PF00017 0.499
LIG_SH2_CRK 290 294 PF00017 0.352
LIG_SH2_CRK 742 746 PF00017 0.323
LIG_SH2_CRK 786 790 PF00017 0.494
LIG_SH2_NCK_1 1386 1390 PF00017 0.378
LIG_SH2_NCK_1 1404 1408 PF00017 0.336
LIG_SH2_NCK_1 692 696 PF00017 0.328
LIG_SH2_NCK_1 742 746 PF00017 0.384
LIG_SH2_NCK_1 790 794 PF00017 0.421
LIG_SH2_SRC 124 127 PF00017 0.487
LIG_SH2_STAP1 364 368 PF00017 0.393
LIG_SH2_STAP1 464 468 PF00017 0.415
LIG_SH2_STAP1 575 579 PF00017 0.452
LIG_SH2_STAP1 921 925 PF00017 0.459
LIG_SH2_STAT3 1122 1125 PF00017 0.283
LIG_SH2_STAT3 1325 1328 PF00017 0.315
LIG_SH2_STAT3 464 467 PF00017 0.388
LIG_SH2_STAT3 481 484 PF00017 0.448
LIG_SH2_STAT3 921 924 PF00017 0.475
LIG_SH2_STAT5 1023 1026 PF00017 0.441
LIG_SH2_STAT5 1076 1079 PF00017 0.555
LIG_SH2_STAT5 124 127 PF00017 0.380
LIG_SH2_STAT5 131 134 PF00017 0.378
LIG_SH2_STAT5 1325 1328 PF00017 0.386
LIG_SH2_STAT5 171 174 PF00017 0.512
LIG_SH2_STAT5 481 484 PF00017 0.458
LIG_SH2_STAT5 528 531 PF00017 0.461
LIG_SH2_STAT5 657 660 PF00017 0.378
LIG_SH2_STAT5 678 681 PF00017 0.301
LIG_SH2_STAT5 747 750 PF00017 0.348
LIG_SH3_1 104 110 PF00018 0.552
LIG_SH3_1 1404 1410 PF00018 0.584
LIG_SH3_3 1025 1031 PF00018 0.450
LIG_SH3_3 104 110 PF00018 0.655
LIG_SH3_3 1152 1158 PF00018 0.437
LIG_SH3_3 1189 1195 PF00018 0.550
LIG_SH3_3 1313 1319 PF00018 0.439
LIG_SH3_3 1404 1410 PF00018 0.584
LIG_SH3_3 272 278 PF00018 0.569
LIG_SH3_3 543 549 PF00018 0.478
LIG_SH3_3 765 771 PF00018 0.469
LIG_SH3_3 905 911 PF00018 0.392
LIG_SH3_3 93 99 PF00018 0.639
LIG_SUMO_SIM_anti_2 1022 1028 PF11976 0.436
LIG_SUMO_SIM_anti_2 1221 1226 PF11976 0.311
LIG_SUMO_SIM_par_1 1035 1041 PF11976 0.425
LIG_SUMO_SIM_par_1 203 208 PF11976 0.412
LIG_SUMO_SIM_par_1 394 401 PF11976 0.387
LIG_SUMO_SIM_par_1 800 807 PF11976 0.441
LIG_TRAF2_1 100 103 PF00917 0.572
LIG_TRAF2_1 145 148 PF00917 0.658
LIG_TRAF2_2 1454 1459 PF00917 0.421
LIG_TYR_ITIM 294 299 PF00017 0.345
LIG_TYR_ITIM 740 745 PF00017 0.384
LIG_UBA3_1 1396 1403 PF00899 0.607
LIG_UBA3_1 626 631 PF00899 0.308
LIG_UBA3_1 766 774 PF00899 0.352
LIG_UBA3_1 967 973 PF00899 0.435
LIG_WRC_WIRS_1 986 991 PF05994 0.506
LIG_WW_3 106 110 PF00397 0.549
MOD_CDC14_SPxK_1 1315 1318 PF00782 0.368
MOD_CDK_SPK_2 109 114 PF00069 0.510
MOD_CDK_SPxK_1 1312 1318 PF00069 0.401
MOD_CDK_SPxK_1 711 717 PF00069 0.503
MOD_CK1_1 1048 1054 PF00069 0.253
MOD_CK1_1 1079 1085 PF00069 0.366
MOD_CK1_1 1216 1222 PF00069 0.442
MOD_CK1_1 1309 1315 PF00069 0.518
MOD_CK1_1 1345 1351 PF00069 0.307
MOD_CK1_1 1358 1364 PF00069 0.337
MOD_CK1_1 1439 1445 PF00069 0.481
MOD_CK1_1 189 195 PF00069 0.399
MOD_CK1_1 221 227 PF00069 0.591
MOD_CK1_1 316 322 PF00069 0.670
MOD_CK1_1 382 388 PF00069 0.518
MOD_CK1_1 724 730 PF00069 0.557
MOD_CK1_1 836 842 PF00069 0.287
MOD_CK1_1 859 865 PF00069 0.323
MOD_CK1_1 876 882 PF00069 0.392
MOD_CK2_1 1153 1159 PF00069 0.628
MOD_CK2_1 117 123 PF00069 0.541
MOD_CK2_1 1172 1178 PF00069 0.476
MOD_CK2_1 1357 1363 PF00069 0.304
MOD_CK2_1 1392 1398 PF00069 0.312
MOD_CK2_1 1411 1417 PF00069 0.512
MOD_CK2_1 142 148 PF00069 0.588
MOD_CK2_1 416 422 PF00069 0.592
MOD_CK2_1 79 85 PF00069 0.384
MOD_CK2_1 852 858 PF00069 0.465
MOD_CK2_1 985 991 PF00069 0.585
MOD_Cter_Amidation 1011 1014 PF01082 0.270
MOD_DYRK1A_RPxSP_1 109 113 PF00069 0.515
MOD_GlcNHglycan 1112 1115 PF01048 0.440
MOD_GlcNHglycan 1184 1187 PF01048 0.428
MOD_GlcNHglycan 1188 1192 PF01048 0.428
MOD_GlcNHglycan 1198 1201 PF01048 0.453
MOD_GlcNHglycan 126 130 PF01048 0.354
MOD_GlcNHglycan 1308 1311 PF01048 0.597
MOD_GlcNHglycan 1344 1347 PF01048 0.332
MOD_GlcNHglycan 1413 1416 PF01048 0.473
MOD_GlcNHglycan 1444 1447 PF01048 0.490
MOD_GlcNHglycan 1493 1496 PF01048 0.652
MOD_GlcNHglycan 151 154 PF01048 0.548
MOD_GlcNHglycan 1518 1524 PF01048 0.664
MOD_GlcNHglycan 275 278 PF01048 0.607
MOD_GlcNHglycan 316 319 PF01048 0.709
MOD_GlcNHglycan 387 390 PF01048 0.560
MOD_GlcNHglycan 425 428 PF01048 0.660
MOD_GlcNHglycan 433 436 PF01048 0.579
MOD_GlcNHglycan 552 555 PF01048 0.308
MOD_GlcNHglycan 645 648 PF01048 0.328
MOD_GlcNHglycan 700 703 PF01048 0.578
MOD_GlcNHglycan 777 780 PF01048 0.408
MOD_GlcNHglycan 809 812 PF01048 0.437
MOD_GlcNHglycan 821 824 PF01048 0.275
MOD_GlcNHglycan 835 838 PF01048 0.267
MOD_GlcNHglycan 878 881 PF01048 0.423
MOD_GlcNHglycan 897 900 PF01048 0.348
MOD_GlcNHglycan 901 904 PF01048 0.452
MOD_GSK3_1 1081 1088 PF00069 0.382
MOD_GSK3_1 1166 1173 PF00069 0.579
MOD_GSK3_1 1178 1185 PF00069 0.561
MOD_GSK3_1 1196 1203 PF00069 0.483
MOD_GSK3_1 1209 1216 PF00069 0.399
MOD_GSK3_1 1241 1248 PF00069 0.551
MOD_GSK3_1 1299 1306 PF00069 0.543
MOD_GSK3_1 1308 1315 PF00069 0.550
MOD_GSK3_1 1355 1362 PF00069 0.405
MOD_GSK3_1 1411 1418 PF00069 0.645
MOD_GSK3_1 185 192 PF00069 0.569
MOD_GSK3_1 269 276 PF00069 0.615
MOD_GSK3_1 304 311 PF00069 0.464
MOD_GSK3_1 313 320 PF00069 0.607
MOD_GSK3_1 335 342 PF00069 0.452
MOD_GSK3_1 416 423 PF00069 0.617
MOD_GSK3_1 585 592 PF00069 0.359
MOD_GSK3_1 681 688 PF00069 0.280
MOD_GSK3_1 711 718 PF00069 0.545
MOD_GSK3_1 726 733 PF00069 0.400
MOD_GSK3_1 758 765 PF00069 0.314
MOD_GSK3_1 79 86 PF00069 0.508
MOD_GSK3_1 803 810 PF00069 0.389
MOD_GSK3_1 852 859 PF00069 0.351
MOD_GSK3_1 870 877 PF00069 0.388
MOD_GSK3_1 895 902 PF00069 0.350
MOD_GSK3_1 907 914 PF00069 0.299
MOD_LATS_1 486 492 PF00433 0.386
MOD_LATS_1 536 542 PF00433 0.246
MOD_N-GLC_1 1342 1347 PF02516 0.309
MOD_N-GLC_1 1411 1416 PF02516 0.447
MOD_N-GLC_1 180 185 PF02516 0.558
MOD_N-GLC_1 758 763 PF02516 0.361
MOD_N-GLC_1 925 930 PF02516 0.327
MOD_NEK2_1 1038 1043 PF00069 0.253
MOD_NEK2_1 1110 1115 PF00069 0.406
MOD_NEK2_1 1392 1397 PF00069 0.356
MOD_NEK2_1 180 185 PF00069 0.526
MOD_NEK2_1 196 201 PF00069 0.266
MOD_NEK2_1 213 218 PF00069 0.435
MOD_NEK2_1 645 650 PF00069 0.305
MOD_NEK2_1 803 808 PF00069 0.274
MOD_NEK2_1 851 856 PF00069 0.474
MOD_NEK2_1 950 955 PF00069 0.473
MOD_NEK2_2 493 498 PF00069 0.454
MOD_NEK2_2 821 826 PF00069 0.255
MOD_PIKK_1 1079 1085 PF00454 0.286
MOD_PIKK_1 1293 1299 PF00454 0.610
MOD_PIKK_1 1387 1393 PF00454 0.368
MOD_PIKK_1 25 31 PF00454 0.420
MOD_PIKK_1 398 404 PF00454 0.596
MOD_PIKK_1 480 486 PF00454 0.448
MOD_PIKK_1 520 526 PF00454 0.351
MOD_PIKK_1 544 550 PF00454 0.321
MOD_PIKK_1 912 918 PF00454 0.246
MOD_PIKK_1 920 926 PF00454 0.239
MOD_PIKK_1 934 940 PF00454 0.245
MOD_PKA_1 1299 1305 PF00069 0.383
MOD_PKA_1 488 494 PF00069 0.383
MOD_PKA_1 550 556 PF00069 0.287
MOD_PKA_2 1216 1222 PF00069 0.504
MOD_PKA_2 1299 1305 PF00069 0.383
MOD_PKA_2 1382 1388 PF00069 0.362
MOD_PKA_2 1392 1398 PF00069 0.314
MOD_PKA_2 158 164 PF00069 0.573
MOD_PKA_2 172 178 PF00069 0.466
MOD_PKA_2 330 336 PF00069 0.540
MOD_PKA_2 451 457 PF00069 0.468
MOD_PKA_2 487 493 PF00069 0.441
MOD_PKA_2 550 556 PF00069 0.266
MOD_PKA_2 564 570 PF00069 0.287
MOD_PKA_2 859 865 PF00069 0.349
MOD_Plk_1 1342 1348 PF00069 0.456
MOD_Plk_1 1366 1372 PF00069 0.449
MOD_Plk_1 1411 1417 PF00069 0.441
MOD_Plk_1 185 191 PF00069 0.585
MOD_Plk_1 196 202 PF00069 0.472
MOD_Plk_1 446 452 PF00069 0.638
MOD_Plk_1 998 1004 PF00069 0.285
MOD_Plk_2-3 117 123 PF00069 0.547
MOD_Plk_2-3 1459 1465 PF00069 0.530
MOD_Plk_4 1038 1044 PF00069 0.462
MOD_Plk_4 1045 1051 PF00069 0.422
MOD_Plk_4 1345 1351 PF00069 0.339
MOD_Plk_4 1392 1398 PF00069 0.456
MOD_Plk_4 1459 1465 PF00069 0.530
MOD_Plk_4 186 192 PF00069 0.575
MOD_Plk_4 196 202 PF00069 0.398
MOD_Plk_4 278 284 PF00069 0.667
MOD_Plk_4 323 329 PF00069 0.632
MOD_Plk_4 762 768 PF00069 0.289
MOD_Plk_4 985 991 PF00069 0.535
MOD_ProDKin_1 1015 1021 PF00069 0.295
MOD_ProDKin_1 109 115 PF00069 0.597
MOD_ProDKin_1 1134 1140 PF00069 0.579
MOD_ProDKin_1 1312 1318 PF00069 0.561
MOD_ProDKin_1 1436 1442 PF00069 0.477
MOD_ProDKin_1 1450 1456 PF00069 0.574
MOD_ProDKin_1 304 310 PF00069 0.464
MOD_ProDKin_1 379 385 PF00069 0.598
MOD_ProDKin_1 659 665 PF00069 0.446
MOD_ProDKin_1 690 696 PF00069 0.455
MOD_ProDKin_1 711 717 PF00069 0.681
MOD_ProDKin_1 721 727 PF00069 0.535
MOD_ProDKin_1 83 89 PF00069 0.646
MOD_ProDKin_1 878 884 PF00069 0.465
MOD_ProDKin_1 907 913 PF00069 0.477
MOD_ProDKin_1 92 98 PF00069 0.562
MOD_SUMO_rev_2 756 766 PF00179 0.421
TRG_DiLeu_BaEn_1 1022 1027 PF01217 0.267
TRG_DiLeu_BaEn_2 196 202 PF01217 0.336
TRG_DiLeu_BaLyEn_6 1422 1427 PF01217 0.326
TRG_DiLeu_BaLyEn_6 235 240 PF01217 0.321
TRG_ENDOCYTIC_2 1023 1026 PF00928 0.267
TRG_ENDOCYTIC_2 1093 1096 PF00928 0.378
TRG_ENDOCYTIC_2 1126 1129 PF00928 0.379
TRG_ENDOCYTIC_2 1386 1389 PF00928 0.431
TRG_ENDOCYTIC_2 290 293 PF00928 0.420
TRG_ENDOCYTIC_2 296 299 PF00928 0.451
TRG_ENDOCYTIC_2 742 745 PF00928 0.332
TRG_ENDOCYTIC_2 943 946 PF00928 0.359
TRG_ER_diArg_1 1278 1280 PF00400 0.476
TRG_ER_diArg_1 1298 1300 PF00400 0.311
TRG_ER_diArg_1 1424 1426 PF00400 0.436
TRG_ER_diArg_1 1470 1472 PF00400 0.440
TRG_ER_diArg_1 164 166 PF00400 0.584
TRG_ER_diArg_1 255 258 PF00400 0.734
TRG_ER_diArg_1 328 331 PF00400 0.504
TRG_ER_diArg_1 475 477 PF00400 0.505
TRG_ER_diArg_1 487 489 PF00400 0.344
TRG_ER_diArg_1 507 510 PF00400 0.403
TRG_ER_diArg_1 549 551 PF00400 0.321
TRG_ER_diArg_1 638 641 PF00400 0.350
TRG_ER_diArg_1 962 964 PF00400 0.252
TRG_ER_FFAT_2 685 697 PF00635 0.470
TRG_NES_CRM1_1 1015 1030 PF08389 0.267
TRG_NES_CRM1_1 604 615 PF08389 0.286
TRG_NLS_MonoCore_2 1071 1076 PF00514 0.495
TRG_NLS_MonoExtN_4 1072 1077 PF00514 0.497
TRG_Pf-PMV_PEXEL_1 238 242 PF00026 0.383
TRG_Pf-PMV_PEXEL_1 291 295 PF00026 0.345
TRG_Pf-PMV_PEXEL_1 677 681 PF00026 0.336

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P5H2 Leptomonas seymouri 58% 84%
A0A1X0P9B9 Trypanosomatidae 43% 100%
A0A1X0P9W8 Trypanosomatidae 28% 69%
A0A3R7MLF0 Trypanosoma rangeli 44% 100%
A0A3S7WQG7 Leishmania donovani 29% 100%
A0A3S7X7P0 Leishmania donovani 92% 100%
A4HAN8 Leishmania braziliensis 78% 79%
A4HB41 Leishmania braziliensis 31% 68%
A4HTS5 Leishmania infantum 29% 100%
A4I9T1 Leishmania infantum 93% 84%
C9ZM05 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 70%
C9ZMU8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 42% 100%
E9AMK8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 30% 100%
E9B4U2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
E9B5B2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 32% 69%
Q4Q2M1 Leishmania major 31% 69%
Q581T1 Trypanosoma brucei brucei (strain 927/4 GUTat10.1) 31% 71%
V5BKW2 Trypanosoma cruzi 31% 95%
V5BND8 Trypanosoma cruzi 44% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS