OsmC-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

OsmC-like protein

Gene product:

OsmC-like protein, putative

Species:

Leishmania major

UniProt:

Q4Q372_LEIMA

TriTrypDb:

LmjF.34.1300 , LMJLV39_340021200 , LMJSD75_340021200

Length:

356

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q372

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q372

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	247	251	PF00656	0.753
CLV_C14_Caspase3-7	36	40	PF00656	0.538
CLV_NRD_NRD_1	207	209	PF00675	0.705
CLV_NRD_NRD_1	215	217	PF00675	0.601
CLV_NRD_NRD_1	268	270	PF00675	0.662
CLV_NRD_NRD_1	63	65	PF00675	0.505
CLV_NRD_NRD_1	88	90	PF00675	0.595
CLV_PCSK_FUR_1	60	64	PF00082	0.545
CLV_PCSK_KEX2_1	207	209	PF00082	0.705
CLV_PCSK_KEX2_1	215	217	PF00082	0.585
CLV_PCSK_KEX2_1	268	270	PF00082	0.662
CLV_PCSK_KEX2_1	298	300	PF00082	0.710
CLV_PCSK_KEX2_1	62	64	PF00082	0.509
CLV_PCSK_KEX2_1	88	90	PF00082	0.552
CLV_PCSK_PC1ET2_1	298	300	PF00082	0.640
CLV_PCSK_PC1ET2_1	62	64	PF00082	0.494
DEG_Nend_Nbox_1	1	3	PF02207	0.655
DEG_SPOP_SBC_1	251	255	PF00917	0.731
DOC_MAPK_gen_1	95	102	PF00069	0.583
DOC_MAPK_MEF2A_6	95	102	PF00069	0.577
DOC_MAPK_NFAT4_5	95	103	PF00069	0.577
DOC_PP1_RVXF_1	288	294	PF00149	0.517
DOC_PP1_RVXF_1	41	48	PF00149	0.569
DOC_PP1_RVXF_1	89	95	PF00149	0.381
DOC_PP4_FxxP_1	353	356	PF00568	0.527
DOC_USP7_MATH_1	105	109	PF00917	0.628
DOC_USP7_MATH_1	152	156	PF00917	0.456
DOC_USP7_MATH_1	171	175	PF00917	0.418
DOC_USP7_MATH_1	302	306	PF00917	0.740
DOC_USP7_MATH_1	342	346	PF00917	0.792
DOC_USP7_MATH_2	329	335	PF00917	0.638
DOC_WW_Pin1_4	348	353	PF00397	0.711
LIG_14-3-3_CanoR_1	269	275	PF00244	0.661
LIG_14-3-3_CanoR_1	89	95	PF00244	0.462
LIG_Actin_WH2_2	4	22	PF00022	0.519
LIG_BIR_III_4	169	173	PF00653	0.447
LIG_FHA_1	129	135	PF00498	0.498
LIG_FHA_1	252	258	PF00498	0.653
LIG_FHA_2	253	259	PF00498	0.653
LIG_FHA_2	299	305	PF00498	0.748
LIG_FHA_2	34	40	PF00498	0.567
LIG_LIR_Apic_2	351	356	PF02991	0.523
LIG_LIR_Gen_1	68	78	PF02991	0.483
LIG_LIR_Nem_3	68	73	PF02991	0.477
LIG_SH2_CRK	70	74	PF00017	0.560
LIG_SH2_SRC	167	170	PF00017	0.364
LIG_SH2_SRC	37	40	PF00017	0.570
LIG_SH2_STAT5	167	170	PF00017	0.365
LIG_SH2_STAT5	25	28	PF00017	0.577
LIG_SH2_STAT5	37	40	PF00017	0.488
LIG_SH3_3	324	330	PF00018	0.733
LIG_TRAF2_1	101	104	PF00917	0.491
LIG_TRAF2_1	174	177	PF00917	0.449
MOD_CDK_SPxxK_3	348	355	PF00069	0.647
MOD_CK1_1	203	209	PF00069	0.514
MOD_CK1_1	253	259	PF00069	0.692
MOD_CK1_1	272	278	PF00069	0.634
MOD_CK1_1	317	323	PF00069	0.788
MOD_CK1_1	334	340	PF00069	0.825
MOD_CK2_1	171	177	PF00069	0.460
MOD_CK2_1	226	232	PF00069	0.599
MOD_CK2_1	252	258	PF00069	0.653
MOD_CK2_1	90	96	PF00069	0.448
MOD_CK2_1	98	104	PF00069	0.446
MOD_Cter_Amidation	60	63	PF01082	0.513
MOD_GlcNHglycan	113	116	PF01048	0.623
MOD_GlcNHglycan	202	205	PF01048	0.600
MOD_GlcNHglycan	228	231	PF01048	0.656
MOD_GlcNHglycan	246	249	PF01048	0.647
MOD_GlcNHglycan	331	334	PF01048	0.726
MOD_GlcNHglycan	348	351	PF01048	0.659
MOD_GlcNHglycan	39	42	PF01048	0.559
MOD_GSK3_1	107	114	PF00069	0.438
MOD_GSK3_1	124	131	PF00069	0.363
MOD_GSK3_1	233	240	PF00069	0.710
MOD_GSK3_1	252	259	PF00069	0.638
MOD_GSK3_1	269	276	PF00069	0.587
MOD_GSK3_1	298	305	PF00069	0.703
MOD_GSK3_1	314	321	PF00069	0.743
MOD_GSK3_1	33	40	PF00069	0.595
MOD_GSK3_1	331	338	PF00069	0.742
MOD_GSK3_1	342	349	PF00069	0.749
MOD_NEK2_1	98	103	PF00069	0.517
MOD_PIKK_1	107	113	PF00454	0.429
MOD_PIKK_1	335	341	PF00454	0.776
MOD_PKA_1	298	304	PF00069	0.537
MOD_PKA_2	105	111	PF00069	0.554
MOD_PKA_2	2	8	PF00069	0.501
MOD_PKA_2	244	250	PF00069	0.586
MOD_PKA_2	276	282	PF00069	0.581
MOD_PKA_2	298	304	PF00069	0.537
MOD_PKA_2	90	96	PF00069	0.533
MOD_Plk_4	33	39	PF00069	0.550
MOD_ProDKin_1	348	354	PF00069	0.706
MOD_SUMO_for_1	48	51	PF00179	0.582
MOD_SUMO_rev_2	137	145	PF00179	0.411
MOD_SUMO_rev_2	283	291	PF00179	0.524
TRG_ENDOCYTIC_2	70	73	PF00928	0.429
TRG_ER_diArg_1	214	216	PF00400	0.617
TRG_ER_diArg_1	268	270	PF00400	0.568
TRG_ER_diArg_1	88	91	PF00400	0.652
TRG_NLS_MonoExtN_4	60	66	PF00514	0.517
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.483

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILB7	Leptomonas seymouri	54%	99%
A0A1X0PAR8	Trypanosomatidae	44%	100%
A0A3S7X7R4	Leishmania donovani	91%	99%
A0A422NU27	Trypanosoma rangeli	41%	100%
A4HAP7	Leishmania braziliensis	70%	97%
A4I9U3	Leishmania infantum	91%	99%
C9ZMT8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
E9B4V4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	99%
V5DJV1	Trypanosoma cruzi	41%	100%