| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 10 |
| NetGPI | no | yes: 0, no: 10 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005634 | nucleus | 5 | 2 |
| GO:0005737 | cytoplasm | 2 | 2 |
| GO:0031974 | membrane-enclosed lumen | 2 | 2 |
| GO:0031981 | nuclear lumen | 5 | 2 |
| GO:0032838 | plasma membrane bounded cell projection cytoplasm | 4 | 2 |
| GO:0043226 | organelle | 2 | 2 |
| GO:0043227 | membrane-bounded organelle | 3 | 2 |
| GO:0043229 | intracellular organelle | 3 | 2 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 2 |
| GO:0043233 | organelle lumen | 3 | 2 |
| GO:0070013 | intracellular organelle lumen | 4 | 2 |
| GO:0097014 | ciliary plasm | 5 | 2 |
| GO:0099568 | cytoplasmic region | 3 | 2 |
| GO:0110165 | cellular anatomical entity | 1 | 2 |
Related structures:
AlphaFold database: Q4Q346
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0000209 | protein polyubiquitination | 8 | 2 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 2 |
| GO:0008152 | metabolic process | 1 | 2 |
| GO:0016567 | protein ubiquitination | 7 | 2 |
| GO:0019538 | protein metabolic process | 3 | 2 |
| GO:0032446 | protein modification by small protein conjugation | 6 | 2 |
| GO:0036211 | protein modification process | 4 | 2 |
| GO:0043170 | macromolecule metabolic process | 3 | 2 |
| GO:0043412 | macromolecule modification | 4 | 2 |
| GO:0044238 | primary metabolic process | 2 | 2 |
| GO:0070647 | protein modification by small protein conjugation or removal | 5 | 2 |
| GO:0071704 | organic substance metabolic process | 2 | 2 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 2 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 7 |
| GO:0004842 | ubiquitin-protein transferase activity | 4 | 3 |
| GO:0016740 | transferase activity | 2 | 4 |
| GO:0016874 | ligase activity | 2 | 6 |
| GO:0019787 | ubiquitin-like protein transferase activity | 3 | 3 |
| GO:0061631 | ubiquitin conjugating enzyme activity | 5 | 3 |
| GO:0061650 | ubiquitin-like protein conjugating enzyme activity | 4 | 3 |
| GO:0140096 | catalytic activity, acting on a protein | 2 | 3 |
| GO:0000166 | nucleotide binding | 3 | 1 |
| GO:0005488 | binding | 1 | 1 |
| GO:0005524 | ATP binding | 5 | 1 |
| GO:0017076 | purine nucleotide binding | 4 | 1 |
| GO:0030554 | adenyl nucleotide binding | 5 | 1 |
| GO:0032553 | ribonucleotide binding | 3 | 1 |
| GO:0032555 | purine ribonucleotide binding | 4 | 1 |
| GO:0032559 | adenyl ribonucleotide binding | 5 | 1 |
| GO:0035639 | purine ribonucleoside triphosphate binding | 4 | 1 |
| GO:0036094 | small molecule binding | 2 | 1 |
| GO:0043167 | ion binding | 2 | 1 |
| GO:0043168 | anion binding | 3 | 1 |
| GO:0097159 | organic cyclic compound binding | 2 | 1 |
| GO:0097367 | carbohydrate derivative binding | 2 | 1 |
| GO:1901265 | nucleoside phosphate binding | 3 | 1 |
| GO:1901363 | heterocyclic compound binding | 2 | 1 |
| GO:0016746 | acyltransferase activity | 3 | 1 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 40 | 44 | PF00656 | 0.319 |
| CLV_NRD_NRD_1 | 7 | 9 | PF00675 | 0.495 |
| CLV_PCSK_KEX2_1 | 7 | 9 | PF00082 | 0.395 |
| CLV_PCSK_SKI1_1 | 124 | 128 | PF00082 | 0.426 |
| CLV_PCSK_SKI1_1 | 83 | 87 | PF00082 | 0.314 |
| DOC_CKS1_1 | 111 | 116 | PF01111 | 0.423 |
| DOC_MAPK_gen_1 | 4 | 13 | PF00069 | 0.402 |
| DOC_PP4_FxxP_1 | 77 | 80 | PF00568 | 0.322 |
| DOC_USP7_MATH_1 | 54 | 58 | PF00917 | 0.341 |
| DOC_USP7_MATH_1 | 91 | 95 | PF00917 | 0.344 |
| DOC_WW_Pin1_4 | 110 | 115 | PF00397 | 0.375 |
| DOC_WW_Pin1_4 | 145 | 150 | PF00397 | 0.456 |
| DOC_WW_Pin1_4 | 21 | 26 | PF00397 | 0.514 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.500 |
| LIG_FHA_1 | 110 | 116 | PF00498 | 0.401 |
| LIG_FHA_1 | 61 | 67 | PF00498 | 0.409 |
| LIG_FHA_2 | 146 | 152 | PF00498 | 0.408 |
| LIG_FHA_2 | 60 | 66 | PF00498 | 0.427 |
| LIG_LIR_Apic_2 | 74 | 80 | PF02991 | 0.386 |
| LIG_LIR_Gen_1 | 12 | 20 | PF02991 | 0.449 |
| LIG_LIR_Gen_1 | 62 | 70 | PF02991 | 0.411 |
| LIG_LIR_Nem_3 | 12 | 16 | PF02991 | 0.443 |
| LIG_LIR_Nem_3 | 129 | 133 | PF02991 | 0.328 |
| LIG_LIR_Nem_3 | 62 | 67 | PF02991 | 0.375 |
| LIG_MAD2 | 83 | 91 | PF02301 | 0.409 |
| LIG_SH2_CRK | 133 | 137 | PF00017 | 0.423 |
| LIG_SH2_CRK | 64 | 68 | PF00017 | 0.409 |
| LIG_SH2_STAP1 | 64 | 68 | PF00017 | 0.409 |
| LIG_SH3_3 | 108 | 114 | PF00018 | 0.409 |
| LIG_SH3_3 | 48 | 54 | PF00018 | 0.333 |
| LIG_SH3_3 | 73 | 79 | PF00018 | 0.296 |
| LIG_TRAF2_1 | 148 | 151 | PF00917 | 0.409 |
| MOD_CDK_SPxxK_3 | 21 | 28 | PF00069 | 0.307 |
| MOD_CK1_1 | 2 | 8 | PF00069 | 0.533 |
| MOD_CK2_1 | 145 | 151 | PF00069 | 0.408 |
| MOD_GlcNHglycan | 21 | 24 | PF01048 | 0.472 |
| MOD_GSK3_1 | 19 | 26 | PF00069 | 0.482 |
| MOD_NEK2_1 | 19 | 24 | PF00069 | 0.415 |
| MOD_NEK2_2 | 54 | 59 | PF00069 | 0.331 |
| MOD_PKA_2 | 14 | 20 | PF00069 | 0.487 |
| MOD_PKA_2 | 159 | 165 | PF00069 | 0.576 |
| MOD_Plk_4 | 54 | 60 | PF00069 | 0.331 |
| MOD_ProDKin_1 | 110 | 116 | PF00069 | 0.375 |
| MOD_ProDKin_1 | 145 | 151 | PF00069 | 0.456 |
| MOD_ProDKin_1 | 21 | 27 | PF00069 | 0.506 |
| MOD_SUMO_rev_2 | 107 | 112 | PF00179 | 0.414 |
| TRG_ENDOCYTIC_2 | 133 | 136 | PF00928 | 0.423 |
| TRG_ENDOCYTIC_2 | 64 | 67 | PF00928 | 0.373 |
| TRG_ER_diArg_1 | 47 | 50 | PF00400 | 0.423 |
| TRG_ER_diArg_1 | 6 | 8 | PF00400 | 0.508 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1IA94 | Leptomonas seymouri | 59% | 100% |
| A0A0S4IWQ9 | Bodo saltans | 34% | 86% |
| A0A0S4KJ33 | Bodo saltans | 25% | 100% |
| A0A1X0NH68 | Trypanosomatidae | 26% | 100% |
| A0A1X0NT81 | Trypanosomatidae | 28% | 79% |
| A0A1X0NW06 | Trypanosomatidae | 32% | 100% |
| A0A1X0P9M3 | Trypanosomatidae | 28% | 100% |
| A0A3Q8II37 | Leishmania donovani | 92% | 100% |
| A0A422MVJ2 | Trypanosoma rangeli | 26% | 100% |
| A0A422MW82 | Trypanosoma rangeli | 32% | 100% |
| A0A422NDI3 | Trypanosoma rangeli | 29% | 78% |
| A0A422NWQ7 | Trypanosoma rangeli | 27% | 100% |
| A4HAM6 | Leishmania braziliensis | 80% | 100% |
| A4I9W7 | Leishmania infantum | 92% | 100% |
| A5PKP9 | Xenopus laevis | 25% | 100% |
| C9ZMR5 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 31% | 100% |
| C9ZNM0 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 26% | 100% |
| C9ZW85 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 25% | 100% |
| E9B4Y0 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 93% | 100% |
| O14933 | Homo sapiens | 27% | 100% |
| O74201 | Candida albicans (strain SC5314 / ATCC MYA-2876) | 27% | 93% |
| P06104 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 28% | 97% |
| P0CS16 | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) | 26% | 98% |
| P0CS17 | Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) | 26% | 98% |
| P23566 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 25% | 100% |
| P25153 | Drosophila melanogaster | 27% | 100% |
| P25865 | Arabidopsis thaliana | 27% | 100% |
| P25866 | Triticum aestivum | 26% | 100% |
| P25868 | Triticum aestivum | 25% | 99% |
| P34477 | Caenorhabditis elegans | 29% | 100% |
| P35130 | Medicago sativa | 27% | 100% |
| P42745 | Arabidopsis thaliana | 27% | 100% |
| P42746 | Arabidopsis thaliana | 26% | 100% |
| P49459 | Homo sapiens | 29% | 100% |
| P52478 | Caenorhabditis elegans | 25% | 86% |
| P62253 | Homo sapiens | 27% | 98% |
| P62254 | Mus musculus | 27% | 98% |
| P62255 | Rattus norvegicus | 27% | 98% |
| P63146 | Homo sapiens | 30% | 100% |
| P63147 | Mus musculus | 30% | 100% |
| P63148 | Oryctolagus cuniculus | 30% | 100% |
| P63149 | Rattus norvegicus | 30% | 100% |
| Q32P99 | Bos taurus | 30% | 100% |
| Q42540 | Arabidopsis thaliana | 30% | 100% |
| Q42541 | Arabidopsis thaliana | 30% | 100% |
| Q4PFA5 | Ustilago maydis (strain 521 / FGSC 9021) | 27% | 90% |
| Q4WLA7 | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) | 24% | 100% |
| Q553F3 | Dictyostelium discoideum | 29% | 100% |
| Q5UQC9 | Acanthamoeba polyphaga mimivirus | 25% | 100% |
| Q6BU36 | Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) | 27% | 99% |
| Q6C093 | Yarrowia lipolytica (strain CLIB 122 / E 150) | 30% | 100% |
| Q6C9W0 | Yarrowia lipolytica (strain CLIB 122 / E 150) | 31% | 93% |
| Q6CUD9 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 28% | 100% |
| Q6DCZ9 | Xenopus laevis | 28% | 91% |
| Q6FR76 | Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) | 28% | 99% |
| Q6P8D9 | Xenopus tropicalis | 28% | 91% |
| Q75EB8 | Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) | 28% | 98% |
| Q7K738 | Drosophila melanogaster | 29% | 100% |
| Q8L7T3 | Arabidopsis thaliana | 28% | 92% |
| Q96UP5 | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) | 24% | 100% |
| Q9LJZ5 | Arabidopsis thaliana | 28% | 92% |
| Q9P6I1 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 28% | 100% |
| Q9QZU9 | Mus musculus | 29% | 100% |
| Q9VSF3 | Drosophila melanogaster | 26% | 92% |
| Q9VTY6 | Drosophila melanogaster | 28% | 93% |
| Q9Z255 | Mus musculus | 29% | 100% |
| V5BVS1 | Trypanosoma cruzi | 30% | 74% |