ATP-dependent RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase, putative

Species:

Leishmania major

UniProt:

Q4Q2Z6_LEIMA

TriTrypDb:

LmjF.34.2050 , LMJLV39_340025000 , LMJSD75_340025500

Length:

803

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	12
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

Q4Q2Z6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2Z6

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006364	rRNA processing	8	2
GO:0006396	RNA processing	6	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0009987	cellular process	1	2
GO:0016070	RNA metabolic process	5	2
GO:0016072	rRNA metabolic process	7	2
GO:0034470	ncRNA processing	7	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0034660	ncRNA metabolic process	6	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0046483	heterocycle metabolic process	3	2
GO:0071704	organic substance metabolic process	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	12
GO:0003724	RNA helicase activity	3	12
GO:0003743	translation initiation factor activity	4	11
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008135	translation factor activity, RNA binding	3	11
GO:0008186	ATP-dependent activity, acting on RNA	2	12
GO:0016462	pyrophosphatase activity	5	11
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	11
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	11
GO:0016887	ATP hydrolysis activity	7	11
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	11
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0045182	translation regulator activity	1	11
GO:0090079	translation regulator activity, nucleic acid binding	2	11
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	13	17	PF00656	0.633
CLV_C14_Caspase3-7	622	626	PF00656	0.580
CLV_C14_Caspase3-7	630	634	PF00656	0.591
CLV_NRD_NRD_1	309	311	PF00675	0.247
CLV_NRD_NRD_1	465	467	PF00675	0.559
CLV_NRD_NRD_1	49	51	PF00675	0.255
CLV_NRD_NRD_1	567	569	PF00675	0.576
CLV_NRD_NRD_1	620	622	PF00675	0.671
CLV_NRD_NRD_1	756	758	PF00675	0.633
CLV_NRD_NRD_1	778	780	PF00675	0.604
CLV_NRD_NRD_1	789	791	PF00675	0.532
CLV_PCSK_FUR_1	567	571	PF00082	0.594
CLV_PCSK_KEX2_1	258	260	PF00082	0.318
CLV_PCSK_KEX2_1	309	311	PF00082	0.247
CLV_PCSK_KEX2_1	318	320	PF00082	0.247
CLV_PCSK_KEX2_1	427	429	PF00082	0.398
CLV_PCSK_KEX2_1	500	502	PF00082	0.460
CLV_PCSK_KEX2_1	567	569	PF00082	0.567
CLV_PCSK_KEX2_1	620	622	PF00082	0.610
CLV_PCSK_KEX2_1	718	720	PF00082	0.651
CLV_PCSK_KEX2_1	760	762	PF00082	0.628
CLV_PCSK_KEX2_1	778	780	PF00082	0.454
CLV_PCSK_PC1ET2_1	258	260	PF00082	0.346
CLV_PCSK_PC1ET2_1	318	320	PF00082	0.271
CLV_PCSK_PC1ET2_1	427	429	PF00082	0.518
CLV_PCSK_PC1ET2_1	500	502	PF00082	0.460
CLV_PCSK_PC1ET2_1	569	571	PF00082	0.581
CLV_PCSK_PC1ET2_1	718	720	PF00082	0.651
CLV_PCSK_PC1ET2_1	760	762	PF00082	0.716
CLV_PCSK_PC7_1	314	320	PF00082	0.307
CLV_PCSK_PC7_1	496	502	PF00082	0.467
CLV_PCSK_PC7_1	563	569	PF00082	0.618
CLV_PCSK_SKI1_1	200	204	PF00082	0.247
CLV_PCSK_SKI1_1	258	262	PF00082	0.314
CLV_PCSK_SKI1_1	31	35	PF00082	0.389
CLV_PCSK_SKI1_1	500	504	PF00082	0.470
CLV_PCSK_SKI1_1	505	509	PF00082	0.508
CLV_PCSK_SKI1_1	632	636	PF00082	0.641
CLV_PCSK_SKI1_1	650	654	PF00082	0.228
CLV_PCSK_SKI1_1	671	675	PF00082	0.295
CLV_PCSK_SKI1_1	696	700	PF00082	0.304
CLV_PCSK_SKI1_1	718	722	PF00082	0.656
DEG_APCC_DBOX_1	473	481	PF00400	0.578
DEG_Nend_Nbox_1	1	3	PF02207	0.629
DEG_SPOP_SBC_1	574	578	PF00917	0.677
DOC_CKS1_1	147	152	PF01111	0.443
DOC_CKS1_1	403	408	PF01111	0.550
DOC_CKS1_1	44	49	PF01111	0.310
DOC_CYCLIN_RxL_1	197	206	PF00134	0.447
DOC_CYCLIN_RxL_1	28	35	PF00134	0.495
DOC_CYCLIN_RxL_1	329	340	PF00134	0.471
DOC_CYCLIN_RxL_1	500	513	PF00134	0.580
DOC_CYCLIN_RxL_1	549	558	PF00134	0.540
DOC_CYCLIN_yClb5_NLxxxL_5	24	33	PF00134	0.465
DOC_CYCLIN_yCln2_LP_2	219	225	PF00134	0.392
DOC_MAPK_FxFP_2	345	348	PF00069	0.471
DOC_MAPK_gen_1	318	326	PF00069	0.447
DOC_MAPK_gen_1	489	497	PF00069	0.392
DOC_MAPK_gen_1	500	509	PF00069	0.514
DOC_MAPK_gen_1	657	667	PF00069	0.299
DOC_MAPK_gen_1	696	705	PF00069	0.440
DOC_MAPK_JIP1_4	503	509	PF00069	0.621
DOC_MAPK_MEF2A_6	249	257	PF00069	0.327
DOC_MAPK_MEF2A_6	503	511	PF00069	0.586
DOC_MAPK_RevD_3	703	719	PF00069	0.590
DOC_PP1_RVXF_1	550	557	PF00149	0.672
DOC_PP2B_LxvP_1	334	337	PF13499	0.447
DOC_PP4_FxxP_1	345	348	PF00568	0.458
DOC_PP4_FxxP_1	42	45	PF00568	0.487
DOC_PP4_FxxP_1	76	79	PF00568	0.454
DOC_USP7_MATH_1	10	14	PF00917	0.645
DOC_USP7_MATH_1	267	271	PF00917	0.385
DOC_USP7_MATH_1	312	316	PF00917	0.533
DOC_USP7_MATH_1	364	368	PF00917	0.556
DOC_USP7_MATH_1	392	396	PF00917	0.541
DOC_USP7_MATH_1	530	534	PF00917	0.489
DOC_USP7_MATH_1	574	578	PF00917	0.738
DOC_USP7_MATH_1	724	728	PF00917	0.704
DOC_USP7_MATH_1	789	793	PF00917	0.454
DOC_USP7_UBL2_3	696	700	PF12436	0.397
DOC_USP7_UBL2_3	760	764	PF12436	0.693
DOC_USP7_UBL2_3	799	803	PF12436	0.697
DOC_USP7_UBL2_3	85	89	PF12436	0.454
DOC_WW_Pin1_4	146	151	PF00397	0.443
DOC_WW_Pin1_4	402	407	PF00397	0.535
DOC_WW_Pin1_4	43	48	PF00397	0.411
DOC_WW_Pin1_4	472	477	PF00397	0.459
DOC_WW_Pin1_4	544	549	PF00397	0.688
DOC_WW_Pin1_4	96	101	PF00397	0.454
LIG_14-3-3_CanoR_1	200	210	PF00244	0.447
LIG_14-3-3_CanoR_1	391	397	PF00244	0.496
LIG_Actin_WH2_2	224	240	PF00022	0.409
LIG_Actin_WH2_2	660	677	PF00022	0.315
LIG_BRCT_BRCA1_1	345	349	PF00533	0.507
LIG_DLG_GKlike_1	102	109	PF00625	0.454
LIG_FHA_1	295	301	PF00498	0.518
LIG_FHA_1	99	105	PF00498	0.455
LIG_FHA_2	373	379	PF00498	0.353
LIG_FHA_2	403	409	PF00498	0.436
LIG_FHA_2	640	646	PF00498	0.410
LIG_FXI_DFP_1	376	380	PF00024	0.397
LIG_GBD_Chelix_1	223	231	PF00786	0.449
LIG_LIR_Apic_2	73	79	PF02991	0.443
LIG_LIR_Gen_1	120	127	PF02991	0.455
LIG_LIR_Gen_1	133	143	PF02991	0.433
LIG_LIR_Gen_1	284	293	PF02991	0.471
LIG_LIR_Gen_1	369	379	PF02991	0.367
LIG_LIR_Gen_1	506	515	PF02991	0.590
LIG_LIR_Gen_1	612	622	PF02991	0.651
LIG_LIR_Gen_1	739	747	PF02991	0.668
LIG_LIR_Gen_1	770	777	PF02991	0.542
LIG_LIR_Nem_3	120	126	PF02991	0.455
LIG_LIR_Nem_3	133	139	PF02991	0.433
LIG_LIR_Nem_3	375	379	PF02991	0.381
LIG_LIR_Nem_3	408	414	PF02991	0.437
LIG_LIR_Nem_3	506	511	PF02991	0.628
LIG_LIR_Nem_3	612	618	PF02991	0.705
LIG_LIR_Nem_3	739	744	PF02991	0.675
LIG_NRBOX	252	258	PF00104	0.351
LIG_Pex14_2	281	285	PF04695	0.524
LIG_Pex14_2	345	349	PF04695	0.496
LIG_PTB_Apo_2	341	348	PF02174	0.447
LIG_PTB_Apo_2	623	630	PF02174	0.707
LIG_PTB_Phospho_1	623	629	PF10480	0.705
LIG_SH2_CRK	411	415	PF00017	0.452
LIG_SH2_PTP2	382	385	PF00017	0.369
LIG_SH2_STAP1	694	698	PF00017	0.304
LIG_SH2_STAT5	382	385	PF00017	0.351
LIG_SH2_STAT5	662	665	PF00017	0.334
LIG_SH3_3	144	150	PF00018	0.443
LIG_SH3_3	345	351	PF00018	0.458
LIG_SH3_3	41	47	PF00018	0.422
LIG_SH3_3	473	479	PF00018	0.431
LIG_SH3_3	587	593	PF00018	0.675
LIG_SH3_3	94	100	PF00018	0.484
LIG_SUMO_SIM_anti_2	320	328	PF11976	0.448
LIG_TRAF2_1	461	464	PF00917	0.486
LIG_TRAF2_1	642	645	PF00917	0.334
LIG_TRAF2_1	770	773	PF00917	0.557
LIG_UBA3_1	253	258	PF00899	0.353
LIG_UBA3_1	33	39	PF00899	0.486
LIG_UBA3_1	507	516	PF00899	0.557
LIG_UBA3_1	673	678	PF00899	0.347
LIG_UBA3_1	77	85	PF00899	0.294
LIG_WRC_WIRS_1	24	29	PF05994	0.456
LIG_WRC_WIRS_1	313	318	PF05994	0.420
LIG_WRC_WIRS_1	373	378	PF05994	0.366
LIG_WRC_WIRS_1	768	773	PF05994	0.564
MOD_CDC14_SPxK_1	99	102	PF00782	0.310
MOD_CDK_SPxK_1	146	152	PF00069	0.294
MOD_CDK_SPxK_1	96	102	PF00069	0.310
MOD_CDK_SPxxK_3	43	50	PF00069	0.310
MOD_CK1_1	294	300	PF00069	0.368
MOD_CK1_1	372	378	PF00069	0.369
MOD_CK1_1	43	49	PF00069	0.427
MOD_CK1_1	576	582	PF00069	0.771
MOD_CK1_1	603	609	PF00069	0.662
MOD_CK1_1	70	76	PF00069	0.294
MOD_CK1_1	792	798	PF00069	0.484
MOD_CK2_1	530	536	PF00069	0.629
MOD_CK2_1	552	558	PF00069	0.550
MOD_CK2_1	639	645	PF00069	0.384
MOD_CK2_1	767	773	PF00069	0.567
MOD_Cter_Amidation	749	752	PF01082	0.605
MOD_Cter_Amidation	755	758	PF01082	0.630
MOD_Cter_Amidation	797	800	PF01082	0.689
MOD_GlcNHglycan	12	15	PF01048	0.587
MOD_GlcNHglycan	203	206	PF01048	0.295
MOD_GlcNHglycan	215	218	PF01048	0.367
MOD_GlcNHglycan	239	242	PF01048	0.368
MOD_GlcNHglycan	269	272	PF01048	0.308
MOD_GlcNHglycan	297	300	PF01048	0.302
MOD_GlcNHglycan	366	369	PF01048	0.414
MOD_GlcNHglycan	394	397	PF01048	0.559
MOD_GlcNHglycan	69	72	PF01048	0.294
MOD_GlcNHglycan	794	797	PF01048	0.739
MOD_GSK3_1	10	17	PF00069	0.672
MOD_GSK3_1	158	165	PF00069	0.299
MOD_GSK3_1	291	298	PF00069	0.441
MOD_GSK3_1	525	532	PF00069	0.653
MOD_GSK3_1	575	582	PF00069	0.688
MOD_GSK3_1	632	639	PF00069	0.673
MOD_GSK3_1	98	105	PF00069	0.344
MOD_N-GLC_1	343	348	PF02516	0.299
MOD_N-GLC_1	450	455	PF02516	0.577
MOD_NEK2_1	138	143	PF00069	0.329
MOD_NEK2_1	162	167	PF00069	0.315
MOD_NEK2_1	203	208	PF00069	0.296
MOD_NEK2_1	237	242	PF00069	0.363
MOD_NEK2_1	276	281	PF00069	0.299
MOD_NEK2_1	288	293	PF00069	0.299
MOD_NEK2_1	450	455	PF00069	0.472
MOD_NEK2_1	485	490	PF00069	0.523
MOD_NEK2_1	529	534	PF00069	0.638
MOD_NEK2_1	65	70	PF00069	0.294
MOD_NEK2_1	653	658	PF00069	0.420
MOD_NEK2_1	698	703	PF00069	0.457
MOD_NEK2_1	80	85	PF00069	0.294
MOD_NEK2_2	627	632	PF00069	0.645
MOD_PIKK_1	724	730	PF00454	0.660
MOD_PIKK_1	789	795	PF00454	0.464
MOD_PK_1	319	325	PF00069	0.335
MOD_PKA_1	318	324	PF00069	0.299
MOD_PKA_1	455	461	PF00069	0.488
MOD_PKA_1	620	626	PF00069	0.591
MOD_PKA_2	318	324	PF00069	0.315
MOD_PKA_2	530	536	PF00069	0.573
MOD_PKA_2	620	626	PF00069	0.608
MOD_PKA_2	789	795	PF00069	0.533
MOD_Plk_1	102	108	PF00069	0.310
MOD_Plk_1	158	164	PF00069	0.299
MOD_Plk_1	319	325	PF00069	0.384
MOD_Plk_1	343	349	PF00069	0.299
MOD_Plk_1	632	638	PF00069	0.592
MOD_Plk_1	783	789	PF00069	0.631
MOD_Plk_4	206	212	PF00069	0.299
MOD_Plk_4	319	325	PF00069	0.333
MOD_Plk_4	369	375	PF00069	0.352
MOD_ProDKin_1	146	152	PF00069	0.294
MOD_ProDKin_1	402	408	PF00069	0.531
MOD_ProDKin_1	43	49	PF00069	0.310
MOD_ProDKin_1	472	478	PF00069	0.451
MOD_ProDKin_1	544	550	PF00069	0.685
MOD_ProDKin_1	96	102	PF00069	0.310
MOD_SUMO_for_1	317	320	PF00179	0.420
MOD_SUMO_for_1	677	680	PF00179	0.299
MOD_SUMO_rev_2	228	234	PF00179	0.451
MOD_SUMO_rev_2	277	281	PF00179	0.394
MOD_SUMO_rev_2	493	502	PF00179	0.483
TRG_DiLeu_BaEn_1	710	715	PF01217	0.599
TRG_DiLeu_BaEn_4	416	422	PF01217	0.417
TRG_DiLeu_BaLyEn_6	149	154	PF01217	0.310
TRG_DiLeu_BaLyEn_6	29	34	PF01217	0.403
TRG_DiLeu_BaLyEn_6	334	339	PF01217	0.288
TRG_ENDOCYTIC_2	371	374	PF00928	0.332
TRG_ENDOCYTIC_2	382	385	PF00928	0.335
TRG_ENDOCYTIC_2	411	414	PF00928	0.402
TRG_ENDOCYTIC_2	662	665	PF00928	0.334
TRG_ER_diArg_1	309	311	PF00400	0.384
TRG_ER_diArg_1	567	570	PF00400	0.690
TRG_ER_diArg_1	777	779	PF00400	0.672
TRG_ER_diLys_1	799	803	PF00400	0.666
TRG_NLS_MonoExtC_3	499	504	PF00514	0.590
TRG_NLS_MonoExtC_3	656	661	PF00514	0.288
TRG_NLS_MonoExtC_3	756	761	PF00514	0.627
TRG_NLS_MonoExtC_3	798	803	PF00514	0.681
TRG_NLS_MonoExtN_4	452	458	PF00514	0.470
TRG_NLS_MonoExtN_4	657	662	PF00514	0.288
TRG_NLS_MonoExtN_4	716	722	PF00514	0.640
TRG_NLS_MonoExtN_4	754	761	PF00514	0.626
TRG_Pf-PMV_PEXEL_1	102	107	PF00026	0.294
TRG_Pf-PMV_PEXEL_1	168	173	PF00026	0.446
TRG_Pf-PMV_PEXEL_1	427	431	PF00026	0.438

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE92	Leptomonas seymouri	86%	98%
A0A0S4JD47	Bodo saltans	59%	98%
A0A1X0P9U0	Trypanosomatidae	66%	96%
A0A3Q8ID91	Leishmania donovani	31%	100%
A0A3R7NR45	Trypanosoma rangeli	66%	97%
A0A3S5H7C7	Leishmania donovani	23%	100%
A0A3S7X7Z2	Leishmania donovani	96%	100%
A1CTZ6	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	33%	86%
A1DNG2	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	32%	86%
A2QRY2	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	33%	86%
A2YV85	Oryza sativa subsp. indica	37%	94%
A3BT52	Oryza sativa subsp. japonica	37%	94%
A3LZT3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	32%	86%
A4HAR7	Leishmania braziliensis	88%	100%
A4HGR1	Leishmania braziliensis	33%	100%
A4I3T6	Leishmania infantum	31%	100%
A4I9Y2	Leishmania infantum	96%	100%
A4R5B8	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	35%	88%
A5DZT7	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	29%	85%
A6QUM7	Ajellomyces capsulatus (strain NAm1 / WU24)	35%	89%
A6ZXU0	Saccharomyces cerevisiae (strain YJM789)	31%	81%
A7ESL7	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	40%	87%
A7TGW7	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	31%	82%
C9ZMQ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	64%	95%
E9AH36	Leishmania infantum	23%	100%
E9AWL4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B4Z0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
O49289	Arabidopsis thaliana	37%	95%
P0CR06	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	31%	100%
P0CR07	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	31%	100%
Q09719	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	95%
Q0CMM8	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	34%	87%
Q0UMB6	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	91%
Q12389	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	81%
Q2UHC1	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	34%	86%
Q4HZ42	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	33%	90%
Q4Q858	Leishmania major	33%	100%
Q4QAV6	Leishmania major	23%	100%
Q5ANB2	Candida albicans (strain SC5314 / ATCC MYA-2876)	29%	88%
Q5BFU7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	33%	86%
Q6C7X8	Yarrowia lipolytica (strain CLIB 122 / E 150)	32%	87%
Q6FNA2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	32%	83%
Q757U8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	32%	84%
Q8K4L0	Mus musculus	37%	92%
Q8NJM2	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	33%	92%
Q8TDD1	Homo sapiens	38%	91%
V5DJX8	Trypanosoma cruzi	69%	100%