Putative dual specificity protein phosphatase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinatase, putative

Species:

Leishmania major

UniProt:

Q4Q2Y1_LEIMA

TriTrypDb:

LmjF.34.2190 , LMJLV39_340026700 , LMJSD75_340027500

Length:

1382

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005929	cilium	4	7
GO:0042995	cell projection	2	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0110165	cellular anatomical entity	1	7
GO:0120025	plasma membrane bounded cell projection	3	7

Expansion

Sequence features

Q4Q2Y1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	7
GO:0006470	protein dephosphorylation	5	7
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009966	regulation of signal transduction	4	2
GO:0009968	negative regulation of signal transduction	5	2
GO:0009987	cellular process	1	7
GO:0010646	regulation of cell communication	4	2
GO:0010648	negative regulation of cell communication	5	2
GO:0016310	phosphorylation	5	7
GO:0016311	dephosphorylation	5	7
GO:0019538	protein metabolic process	3	7
GO:0023051	regulation of signaling	3	2
GO:0023057	negative regulation of signaling	4	2
GO:0036211	protein modification process	4	7
GO:0043170	macromolecule metabolic process	3	7
GO:0043408	regulation of MAPK cascade	6	2
GO:0043409	negative regulation of MAPK cascade	7	2
GO:0043412	macromolecule modification	4	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0048519	negative regulation of biological process	3	2
GO:0048523	negative regulation of cellular process	4	2
GO:0048583	regulation of response to stimulus	3	2
GO:0048585	negative regulation of response to stimulus	4	2
GO:0050789	regulation of biological process	2	2
GO:0050794	regulation of cellular process	3	2
GO:0065007	biological regulation	1	2
GO:0071704	organic substance metabolic process	2	7
GO:1901564	organonitrogen compound metabolic process	3	7
GO:1902531	regulation of intracellular signal transduction	5	2
GO:1902532	negative regulation of intracellular signal transduction	6	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004672	protein kinase activity	3	7
GO:0004721	phosphoprotein phosphatase activity	3	7
GO:0004725	protein tyrosine phosphatase activity	4	6
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4	7
GO:0008330	protein tyrosine/threonine phosphatase activity	4	2
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7
GO:0016787	hydrolase activity	2	7
GO:0016788	hydrolase activity, acting on ester bonds	3	7
GO:0016791	phosphatase activity	5	7
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5	2
GO:0017076	purine nucleotide binding	4	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0033549	MAP kinase phosphatase activity	4	2
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0042578	phosphoric ester hydrolase activity	4	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140096	catalytic activity, acting on a protein	2	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1054	1058	PF00656	0.426
CLV_C14_Caspase3-7	1066	1070	PF00656	0.275
CLV_C14_Caspase3-7	1100	1104	PF00656	0.374
CLV_C14_Caspase3-7	3	7	PF00656	0.338
CLV_C14_Caspase3-7	41	45	PF00656	0.365
CLV_C14_Caspase3-7	564	568	PF00656	0.245
CLV_C14_Caspase3-7	616	620	PF00656	0.345
CLV_C14_Caspase3-7	724	728	PF00656	0.484
CLV_NRD_NRD_1	1042	1044	PF00675	0.315
CLV_NRD_NRD_1	106	108	PF00675	0.335
CLV_NRD_NRD_1	1247	1249	PF00675	0.315
CLV_NRD_NRD_1	169	171	PF00675	0.315
CLV_NRD_NRD_1	354	356	PF00675	0.393
CLV_NRD_NRD_1	424	426	PF00675	0.315
CLV_NRD_NRD_1	442	444	PF00675	0.315
CLV_NRD_NRD_1	457	459	PF00675	0.295
CLV_NRD_NRD_1	463	465	PF00675	0.315
CLV_NRD_NRD_1	966	968	PF00675	0.547
CLV_PCSK_KEX2_1	105	107	PF00082	0.330
CLV_PCSK_KEX2_1	1328	1330	PF00082	0.345
CLV_PCSK_KEX2_1	169	171	PF00082	0.315
CLV_PCSK_KEX2_1	329	331	PF00082	0.345
CLV_PCSK_KEX2_1	424	426	PF00082	0.315
CLV_PCSK_KEX2_1	442	444	PF00082	0.315
CLV_PCSK_KEX2_1	457	459	PF00082	0.229
CLV_PCSK_PC1ET2_1	1328	1330	PF00082	0.345
CLV_PCSK_PC1ET2_1	329	331	PF00082	0.345
CLV_PCSK_SKI1_1	106	110	PF00082	0.343
CLV_PCSK_SKI1_1	1316	1320	PF00082	0.315
CLV_PCSK_SKI1_1	1351	1355	PF00082	0.315
CLV_PCSK_SKI1_1	169	173	PF00082	0.315
CLV_PCSK_SKI1_1	438	442	PF00082	0.294
CLV_PCSK_SKI1_1	630	634	PF00082	0.245
CLV_PCSK_SKI1_1	662	666	PF00082	0.457
CLV_PCSK_SKI1_1	817	821	PF00082	0.484
CLV_PCSK_SKI1_1	872	876	PF00082	0.462
CLV_PCSK_SKI1_1	95	99	PF00082	0.323
CLV_PCSK_SKI1_1	968	972	PF00082	0.551
DEG_APCC_DBOX_1	105	113	PF00400	0.314
DEG_APCC_DBOX_1	168	176	PF00400	0.315
DEG_APCC_KENBOX_2	138	142	PF00400	0.315
DEG_MDM2_SWIB_1	610	618	PF02201	0.395
DEG_Nend_Nbox_1	1	3	PF02207	0.329
DEG_SCF_FBW7_1	942	947	PF00400	0.437
DEG_SPOP_SBC_1	348	352	PF00917	0.411
DOC_ANK_TNKS_1	442	449	PF00023	0.395
DOC_CKS1_1	1126	1131	PF01111	0.506
DOC_CKS1_1	641	646	PF01111	0.395
DOC_CYCLIN_RxL_1	103	113	PF00134	0.312
DOC_CYCLIN_RxL_1	454	463	PF00134	0.395
DOC_CYCLIN_yClb5_NLxxxL_5	1208	1214	PF00134	0.402
DOC_CYCLIN_yCln2_LP_2	952	958	PF00134	0.399
DOC_MAPK_DCC_7	795	805	PF00069	0.348
DOC_MAPK_gen_1	1184	1193	PF00069	0.432
DOC_MAPK_gen_1	167	177	PF00069	0.294
DOC_MAPK_gen_1	329	336	PF00069	0.345
DOC_MAPK_gen_1	454	462	PF00069	0.350
DOC_MAPK_gen_1	962	971	PF00069	0.494
DOC_MAPK_JIP1_4	330	336	PF00069	0.395
DOC_MAPK_JIP1_4	749	755	PF00069	0.405
DOC_MAPK_MEF2A_6	1187	1195	PF00069	0.378
DOC_MAPK_MEF2A_6	167	175	PF00069	0.299
DOC_MAPK_MEF2A_6	18	25	PF00069	0.310
DOC_MAPK_MEF2A_6	414	423	PF00069	0.315
DOC_MAPK_MEF2A_6	9	17	PF00069	0.384
DOC_PP1_RVXF_1	456	463	PF00149	0.395
DOC_PP1_RVXF_1	669	676	PF00149	0.316
DOC_PP1_RVXF_1	96	103	PF00149	0.325
DOC_PP1_SILK_1	438	443	PF00149	0.282
DOC_PP2B_LxvP_1	444	447	PF13499	0.395
DOC_PP2B_LxvP_1	950	953	PF13499	0.475
DOC_PP2B_LxvP_1	969	972	PF13499	0.484
DOC_PP2B_PxIxI_1	1214	1220	PF00149	0.480
DOC_USP7_MATH_1	1112	1116	PF00917	0.441
DOC_USP7_MATH_1	1143	1147	PF00917	0.330
DOC_USP7_MATH_1	1172	1176	PF00917	0.382
DOC_USP7_MATH_1	21	25	PF00917	0.291
DOC_USP7_MATH_1	285	289	PF00917	0.315
DOC_USP7_MATH_1	69	73	PF00917	0.405
DOC_USP7_MATH_1	694	698	PF00917	0.530
DOC_USP7_MATH_1	7	11	PF00917	0.397
DOC_USP7_MATH_1	77	81	PF00917	0.476
DOC_USP7_MATH_1	842	846	PF00917	0.411
DOC_USP7_MATH_1	856	860	PF00917	0.449
DOC_USP7_MATH_1	861	865	PF00917	0.468
DOC_USP7_MATH_1	922	926	PF00917	0.500
DOC_USP7_MATH_1	944	948	PF00917	0.445
DOC_USP7_UBL2_3	325	329	PF12436	0.345
DOC_USP7_UBL2_3	434	438	PF12436	0.294
DOC_USP7_UBL2_3	964	968	PF12436	0.443
DOC_WW_Pin1_4	1125	1130	PF00397	0.542
DOC_WW_Pin1_4	1159	1164	PF00397	0.424
DOC_WW_Pin1_4	506	511	PF00397	0.345
DOC_WW_Pin1_4	583	588	PF00397	0.391
DOC_WW_Pin1_4	640	645	PF00397	0.395
DOC_WW_Pin1_4	72	77	PF00397	0.468
DOC_WW_Pin1_4	940	945	PF00397	0.541
LIG_14-3-3_CanoR_1	1135	1140	PF00244	0.386
LIG_14-3-3_CanoR_1	1239	1247	PF00244	0.315
LIG_14-3-3_CanoR_1	1286	1290	PF00244	0.315
LIG_14-3-3_CanoR_1	1316	1322	PF00244	0.315
LIG_14-3-3_CanoR_1	160	168	PF00244	0.366
LIG_14-3-3_CanoR_1	180	188	PF00244	0.183
LIG_14-3-3_CanoR_1	306	312	PF00244	0.509
LIG_14-3-3_CanoR_1	355	360	PF00244	0.368
LIG_14-3-3_CanoR_1	414	421	PF00244	0.315
LIG_14-3-3_CanoR_1	671	676	PF00244	0.315
LIG_14-3-3_CanoR_1	9	14	PF00244	0.346
LIG_14-3-3_CanoR_1	900	906	PF00244	0.391
LIG_14-3-3_CanoR_1	957	961	PF00244	0.546
LIG_14-3-3_CanoR_1	988	997	PF00244	0.507
LIG_Actin_RPEL_3	179	198	PF02755	0.345
LIG_AP2alpha_2	714	716	PF02296	0.432
LIG_BRCT_BRCA1_1	1137	1141	PF00533	0.312
LIG_BRCT_BRCA1_1	361	365	PF00533	0.372
LIG_BRCT_BRCA1_1	427	431	PF00533	0.395
LIG_BRCT_BRCA1_1	622	626	PF00533	0.245
LIG_Clathr_ClatBox_1	1357	1361	PF01394	0.315
LIG_Clathr_ClatBox_1	296	300	PF01394	0.305
LIG_CtBP_PxDLS_1	221	225	PF00389	0.315
LIG_deltaCOP1_diTrp_1	264	268	PF00928	0.315
LIG_EVH1_2	234	238	PF00568	0.315
LIG_FHA_1	1126	1132	PF00498	0.477
LIG_FHA_1	1176	1182	PF00498	0.416
LIG_FHA_1	1190	1196	PF00498	0.341
LIG_FHA_1	1251	1257	PF00498	0.345
LIG_FHA_1	1317	1323	PF00498	0.315
LIG_FHA_1	244	250	PF00498	0.294
LIG_FHA_1	348	354	PF00498	0.409
LIG_FHA_1	416	422	PF00498	0.315
LIG_FHA_1	62	68	PF00498	0.454
LIG_FHA_1	623	629	PF00498	0.383
LIG_FHA_1	641	647	PF00498	0.227
LIG_FHA_1	749	755	PF00498	0.559
LIG_FHA_1	768	774	PF00498	0.211
LIG_FHA_1	845	851	PF00498	0.418
LIG_FHA_2	509	515	PF00498	0.294
LIG_FHA_2	562	568	PF00498	0.301
LIG_FHA_2	680	686	PF00498	0.443
LIG_FHA_2	699	705	PF00498	0.382
LIG_FHA_2	823	829	PF00498	0.521
LIG_FHA_2	941	947	PF00498	0.500
LIG_Integrin_isoDGR_2	898	900	PF01839	0.343
LIG_Integrin_isoDGR_2	936	938	PF01839	0.448
LIG_IRF3_LxIS_1	1019	1025	PF10401	0.345
LIG_LIR_Apic_2	1010	1015	PF02991	0.403
LIG_LIR_Apic_2	1363	1368	PF02991	0.507
LIG_LIR_Gen_1	1048	1056	PF02991	0.338
LIG_LIR_Gen_1	1081	1088	PF02991	0.335
LIG_LIR_Gen_1	1094	1102	PF02991	0.346
LIG_LIR_Gen_1	1218	1229	PF02991	0.358
LIG_LIR_Gen_1	286	297	PF02991	0.315
LIG_LIR_Gen_1	608	618	PF02991	0.315
LIG_LIR_Gen_1	901	908	PF02991	0.510
LIG_LIR_LC3C_4	345	348	PF02991	0.346
LIG_LIR_Nem_3	1048	1052	PF02991	0.338
LIG_LIR_Nem_3	1081	1085	PF02991	0.338
LIG_LIR_Nem_3	1094	1098	PF02991	0.348
LIG_LIR_Nem_3	1200	1205	PF02991	0.511
LIG_LIR_Nem_3	1218	1224	PF02991	0.379
LIG_LIR_Nem_3	209	215	PF02991	0.294
LIG_LIR_Nem_3	286	292	PF02991	0.315
LIG_LIR_Nem_3	554	558	PF02991	0.315
LIG_LIR_Nem_3	608	613	PF02991	0.315
LIG_LIR_Nem_3	668	673	PF02991	0.394
LIG_LIR_Nem_3	901	905	PF02991	0.551
LIG_PCNA_yPIPBox_3	186	198	PF02747	0.294
LIG_Pex14_1	1221	1225	PF04695	0.357
LIG_Pex14_1	309	313	PF04695	0.345
LIG_Pex14_2	212	216	PF04695	0.294
LIG_Pex14_2	299	303	PF04695	0.315
LIG_Pex14_2	555	559	PF04695	0.315
LIG_Pex14_2	610	614	PF04695	0.395
LIG_PTB_Apo_2	1347	1354	PF02174	0.315
LIG_PTB_Apo_2	669	676	PF02174	0.416
LIG_REV1ctd_RIR_1	339	347	PF16727	0.335
LIG_RPA_C_Fungi	807	819	PF08784	0.472
LIG_SH2_CRK	1012	1016	PF00017	0.405
LIG_SH2_CRK	1049	1053	PF00017	0.315
LIG_SH2_CRK	1247	1251	PF00017	0.315
LIG_SH2_CRK	289	293	PF00017	0.315
LIG_SH2_CRK	437	441	PF00017	0.305
LIG_SH2_CRK	576	580	PF00017	0.395
LIG_SH2_SRC	1012	1015	PF00017	0.437
LIG_SH2_STAP1	1206	1210	PF00017	0.419
LIG_SH2_STAT3	396	399	PF00017	0.603
LIG_SH2_STAT5	1084	1087	PF00017	0.333
LIG_SH2_STAT5	1169	1172	PF00017	0.345
LIG_SH2_STAT5	1232	1235	PF00017	0.313
LIG_SH2_STAT5	1254	1257	PF00017	0.294
LIG_SH2_STAT5	1324	1327	PF00017	0.315
LIG_SH2_STAT5	61	64	PF00017	0.359
LIG_SH2_STAT5	669	672	PF00017	0.364
LIG_SH2_STAT5	782	785	PF00017	0.420
LIG_SH3_1	1365	1371	PF00018	0.521
LIG_SH3_3	1008	1014	PF00018	0.404
LIG_SH3_3	1073	1079	PF00018	0.387
LIG_SH3_3	1106	1112	PF00018	0.396
LIG_SH3_3	1260	1266	PF00018	0.315
LIG_SH3_3	1365	1371	PF00018	0.521
LIG_SH3_3	215	221	PF00018	0.506
LIG_SH3_3	234	240	PF00018	0.193
LIG_SH3_3	301	307	PF00018	0.315
LIG_SH3_3	388	394	PF00018	0.321
LIG_SH3_3	463	469	PF00018	0.315
LIG_SH3_3	879	885	PF00018	0.430
LIG_SUMO_SIM_anti_2	1103	1110	PF11976	0.437
LIG_SUMO_SIM_par_1	1018	1023	PF11976	0.405
LIG_SUMO_SIM_par_1	1189	1196	PF11976	0.398
LIG_SUMO_SIM_par_1	1273	1279	PF11976	0.315
LIG_SUMO_SIM_par_1	1355	1361	PF11976	0.304
LIG_SUMO_SIM_par_1	1369	1376	PF11976	0.498
LIG_SUMO_SIM_par_1	140	146	PF11976	0.315
LIG_SUMO_SIM_par_1	280	286	PF11976	0.315
LIG_SUMO_SIM_par_1	682	690	PF11976	0.440
LIG_SUMO_SIM_par_1	801	807	PF11976	0.376
LIG_TRAF2_1	1288	1291	PF00917	0.370
LIG_TRAF2_1	511	514	PF00917	0.320
LIG_TRAF2_1	687	690	PF00917	0.437
LIG_TRAF2_1	715	718	PF00917	0.432
LIG_TYR_ITIM	1047	1052	PF00017	0.351
LIG_TYR_ITIM	1322	1327	PF00017	0.345
LIG_TYR_ITIM	435	440	PF00017	0.305
LIG_UBA3_1	1039	1044	PF00899	0.294
LIG_WRC_WIRS_1	1095	1100	PF05994	0.279
LIG_WRC_WIRS_1	1136	1141	PF05994	0.339
LIG_WRC_WIRS_1	370	375	PF05994	0.378
LIG_WRC_WIRS_1	646	651	PF05994	0.315
LIG_WRC_WIRS_1	902	907	PF05994	0.496
LIG_WRC_WIRS_1	99	104	PF05994	0.323
LIG_WW_3	303	307	PF00397	0.320
MOD_CDK_SPK_2	1159	1164	PF00069	0.424
MOD_CDK_SPK_2	940	945	PF00069	0.541
MOD_CDK_SPxxK_3	1159	1166	PF00069	0.422
MOD_CK1_1	1086	1092	PF00069	0.335
MOD_CK1_1	1097	1103	PF00069	0.339
MOD_CK1_1	1115	1121	PF00069	0.355
MOD_CK1_1	1151	1157	PF00069	0.390
MOD_CK1_1	1175	1181	PF00069	0.409
MOD_CK1_1	1237	1243	PF00069	0.315
MOD_CK1_1	1301	1307	PF00069	0.432
MOD_CK1_1	1317	1323	PF00069	0.249
MOD_CK1_1	162	168	PF00069	0.320
MOD_CK1_1	26	32	PF00069	0.349
MOD_CK1_1	358	364	PF00069	0.371
MOD_CK1_1	387	393	PF00069	0.417
MOD_CK1_1	508	514	PF00069	0.347
MOD_CK1_1	72	78	PF00069	0.448
MOD_CK1_1	889	895	PF00069	0.451
MOD_CK1_1	901	907	PF00069	0.413
MOD_CK1_1	992	998	PF00069	0.489
MOD_CK2_1	1060	1066	PF00069	0.315
MOD_CK2_1	1285	1291	PF00069	0.315
MOD_CK2_1	508	514	PF00069	0.253
MOD_CK2_1	565	571	PF00069	0.343
MOD_CK2_1	645	651	PF00069	0.315
MOD_CK2_1	679	685	PF00069	0.434
MOD_CK2_1	694	700	PF00069	0.472
MOD_CK2_1	732	738	PF00069	0.459
MOD_GlcNHglycan	1089	1092	PF01048	0.311
MOD_GlcNHglycan	1115	1118	PF01048	0.434
MOD_GlcNHglycan	1239	1242	PF01048	0.315
MOD_GlcNHglycan	1303	1306	PF01048	0.391
MOD_GlcNHglycan	1316	1319	PF01048	0.264
MOD_GlcNHglycan	1379	1382	PF01048	0.526
MOD_GlcNHglycan	378	381	PF01048	0.449
MOD_GlcNHglycan	492	495	PF01048	0.391
MOD_GlcNHglycan	692	695	PF01048	0.549
MOD_GlcNHglycan	723	726	PF01048	0.520
MOD_GlcNHglycan	765	768	PF01048	0.375
MOD_GlcNHglycan	919	922	PF01048	0.550
MOD_GlcNHglycan	946	949	PF01048	0.433
MOD_GSK3_1	1060	1067	PF00069	0.315
MOD_GSK3_1	1083	1090	PF00069	0.412
MOD_GSK3_1	1097	1104	PF00069	0.278
MOD_GSK3_1	1131	1138	PF00069	0.340
MOD_GSK3_1	1149	1156	PF00069	0.394
MOD_GSK3_1	1250	1257	PF00069	0.294
MOD_GSK3_1	1312	1319	PF00069	0.315
MOD_GSK3_1	1373	1380	PF00069	0.561
MOD_GSK3_1	325	332	PF00069	0.446
MOD_GSK3_1	355	362	PF00069	0.380
MOD_GSK3_1	504	511	PF00069	0.303
MOD_GSK3_1	53	60	PF00069	0.354
MOD_GSK3_1	532	539	PF00069	0.315
MOD_GSK3_1	561	568	PF00069	0.294
MOD_GSK3_1	68	75	PF00069	0.423
MOD_GSK3_1	690	697	PF00069	0.528
MOD_GSK3_1	716	723	PF00069	0.535
MOD_GSK3_1	726	733	PF00069	0.507
MOD_GSK3_1	763	770	PF00069	0.368
MOD_GSK3_1	774	781	PF00069	0.272
MOD_GSK3_1	78	85	PF00069	0.493
MOD_GSK3_1	804	811	PF00069	0.432
MOD_GSK3_1	831	838	PF00069	0.422
MOD_GSK3_1	862	869	PF00069	0.619
MOD_GSK3_1	924	931	PF00069	0.599
MOD_GSK3_1	940	947	PF00069	0.570
MOD_GSK3_1	988	995	PF00069	0.510
MOD_LATS_1	696	702	PF00433	0.506
MOD_N-GLC_1	1060	1065	PF02516	0.315
MOD_N-GLC_1	1122	1127	PF02516	0.375
MOD_N-GLC_1	1131	1136	PF02516	0.297
MOD_N-GLC_1	1172	1177	PF02516	0.385
MOD_N-GLC_1	1215	1220	PF02516	0.401
MOD_N-GLC_1	1250	1255	PF02516	0.294
MOD_N-GLC_1	26	31	PF02516	0.348
MOD_N-GLC_1	425	430	PF02516	0.320
MOD_N-GLC_1	671	676	PF02516	0.390
MOD_N-GLC_1	922	927	PF02516	0.534
MOD_N-GLC_1	992	997	PF02516	0.477
MOD_NEK2_1	1022	1027	PF00069	0.335
MOD_NEK2_1	1045	1050	PF00069	0.329
MOD_NEK2_1	1068	1073	PF00069	0.315
MOD_NEK2_1	1113	1118	PF00069	0.374
MOD_NEK2_1	1250	1255	PF00069	0.427
MOD_NEK2_1	1314	1319	PF00069	0.315
MOD_NEK2_1	1377	1382	PF00069	0.541
MOD_NEK2_1	299	304	PF00069	0.441
MOD_NEK2_1	337	342	PF00069	0.441
MOD_NEK2_1	357	362	PF00069	0.286
MOD_NEK2_1	369	374	PF00069	0.375
MOD_NEK2_1	415	420	PF00069	0.343
MOD_NEK2_1	460	465	PF00069	0.395
MOD_NEK2_1	565	570	PF00069	0.315
MOD_NEK2_1	601	606	PF00069	0.307
MOD_NEK2_1	609	614	PF00069	0.327
MOD_NEK2_1	665	670	PF00069	0.378
MOD_NEK2_1	716	721	PF00069	0.446
MOD_NEK2_1	8	13	PF00069	0.340
MOD_NEK2_1	835	840	PF00069	0.433
MOD_NEK2_1	956	961	PF00069	0.388
MOD_NEK2_2	1234	1239	PF00069	0.395
MOD_NEK2_2	544	549	PF00069	0.345
MOD_NEK2_2	726	731	PF00069	0.552
MOD_PIKK_1	1022	1028	PF00454	0.315
MOD_PIKK_1	1240	1246	PF00454	0.315
MOD_PIKK_1	1296	1302	PF00454	0.315
MOD_PIKK_1	395	401	PF00454	0.445
MOD_PIKK_1	716	722	PF00454	0.450
MOD_PK_1	329	335	PF00069	0.345
MOD_PK_1	384	390	PF00069	0.313
MOD_PK_1	9	15	PF00069	0.429
MOD_PKA_1	329	335	PF00069	0.345
MOD_PKA_1	355	361	PF00069	0.399
MOD_PKA_2	1285	1291	PF00069	0.315
MOD_PKA_2	1337	1343	PF00069	0.245
MOD_PKA_2	159	165	PF00069	0.395
MOD_PKA_2	329	335	PF00069	0.315
MOD_PKA_2	413	419	PF00069	0.315
MOD_PKA_2	8	14	PF00069	0.331
MOD_PKA_2	862	868	PF00069	0.443
MOD_PKA_2	956	962	PF00069	0.537
MOD_PKA_2	989	995	PF00069	0.503
MOD_Plk_1	1034	1040	PF00069	0.304
MOD_Plk_1	1122	1128	PF00069	0.372
MOD_Plk_1	1172	1178	PF00069	0.493
MOD_Plk_1	1189	1195	PF00069	0.330
MOD_Plk_1	1215	1221	PF00069	0.395
MOD_Plk_1	1250	1256	PF00069	0.294
MOD_Plk_1	21	27	PF00069	0.341
MOD_Plk_1	285	291	PF00069	0.315
MOD_Plk_1	299	305	PF00069	0.315
MOD_Plk_1	374	380	PF00069	0.363
MOD_Plk_1	39	45	PF00069	0.359
MOD_Plk_1	544	550	PF00069	0.314
MOD_Plk_1	671	677	PF00069	0.391
MOD_Plk_1	726	732	PF00069	0.537
MOD_Plk_1	737	743	PF00069	0.373
MOD_Plk_1	767	773	PF00069	0.315
MOD_Plk_1	856	862	PF00069	0.455
MOD_Plk_1	889	895	PF00069	0.531
MOD_Plk_2-3	1064	1070	PF00069	0.315
MOD_Plk_2-3	82	88	PF00069	0.462
MOD_Plk_4	1034	1040	PF00069	0.348
MOD_Plk_4	1078	1084	PF00069	0.340
MOD_Plk_4	1101	1107	PF00069	0.348
MOD_Plk_4	1135	1141	PF00069	0.404
MOD_Plk_4	1143	1149	PF00069	0.416
MOD_Plk_4	1197	1203	PF00069	0.388
MOD_Plk_4	1317	1323	PF00069	0.315
MOD_Plk_4	329	335	PF00069	0.315
MOD_Plk_4	337	343	PF00069	0.315
MOD_Plk_4	349	355	PF00069	0.227
MOD_Plk_4	415	421	PF00069	0.335
MOD_Plk_4	436	442	PF00069	0.305
MOD_Plk_4	532	538	PF00069	0.345
MOD_Plk_4	561	567	PF00069	0.260
MOD_Plk_4	601	607	PF00069	0.307
MOD_Plk_4	609	615	PF00069	0.327
MOD_Plk_4	665	671	PF00069	0.310
MOD_Plk_4	679	685	PF00069	0.376
MOD_Plk_4	737	743	PF00069	0.475
MOD_Plk_4	748	754	PF00069	0.304
MOD_Plk_4	778	784	PF00069	0.279
MOD_Plk_4	877	883	PF00069	0.440
MOD_Plk_4	956	962	PF00069	0.525
MOD_ProDKin_1	1125	1131	PF00069	0.537
MOD_ProDKin_1	1159	1165	PF00069	0.423
MOD_ProDKin_1	506	512	PF00069	0.345
MOD_ProDKin_1	583	589	PF00069	0.391
MOD_ProDKin_1	640	646	PF00069	0.395
MOD_ProDKin_1	72	78	PF00069	0.471
MOD_ProDKin_1	940	946	PF00069	0.542
MOD_SUMO_for_1	972	975	PF00179	0.502
MOD_SUMO_rev_2	476	483	PF00179	0.315
TRG_DiLeu_BaEn_1	1035	1040	PF01217	0.294
TRG_DiLeu_BaEn_1	115	120	PF01217	0.315
TRG_DiLeu_BaEn_2	1290	1296	PF01217	0.315
TRG_DiLeu_BaLyEn_6	1012	1017	PF01217	0.405
TRG_DiLeu_BaLyEn_6	104	109	PF01217	0.360
TRG_DiLeu_BaLyEn_6	332	337	PF01217	0.294
TRG_DiLeu_LyEn_5	799	804	PF01217	0.362
TRG_ENDOCYTIC_2	1049	1052	PF00928	0.351
TRG_ENDOCYTIC_2	1095	1098	PF00928	0.349
TRG_ENDOCYTIC_2	1247	1250	PF00928	0.315
TRG_ENDOCYTIC_2	1324	1327	PF00928	0.315
TRG_ENDOCYTIC_2	2	5	PF00928	0.325
TRG_ENDOCYTIC_2	289	292	PF00928	0.315
TRG_ENDOCYTIC_2	437	440	PF00928	0.305
TRG_ER_diArg_1	104	107	PF00400	0.329
TRG_ER_diArg_1	168	170	PF00400	0.315
TRG_ER_diArg_1	423	425	PF00400	0.315
TRG_ER_diArg_1	441	443	PF00400	0.315
TRG_ER_diArg_1	456	458	PF00400	0.295
TRG_ER_diArg_1	46	49	PF00400	0.399
TRG_NES_CRM1_1	1183	1196	PF08389	0.427
TRG_NES_CRM1_1	514	528	PF08389	0.311
TRG_NLS_Bipartite_1	1328	1345	PF00514	0.315
TRG_NLS_MonoExtC_3	1340	1345	PF00514	0.315
TRG_NLS_MonoExtN_4	1338	1345	PF00514	0.245
TRG_Pf-PMV_PEXEL_1	1030	1035	PF00026	0.320
TRG_Pf-PMV_PEXEL_1	106	110	PF00026	0.332
TRG_Pf-PMV_PEXEL_1	1370	1375	PF00026	0.449
TRG_Pf-PMV_PEXEL_1	170	174	PF00026	0.315

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P9A1	Leptomonas seymouri	68%	85%
A0A3Q8IH90	Leishmania donovani	95%	100%
A4HAT1	Leishmania braziliensis	80%	100%
A4I9Z1	Leishmania infantum	95%	100%
E9B505	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%