Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q2S4_LEIMA

TriTrypDb:

LmjF.34.2710 , LMJLV39_340032500 , LMJSD75_340032600

Length:

285

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q2S4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2S4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	70	74	PF00656	0.598
CLV_NRD_NRD_1	101	103	PF00675	0.453
CLV_NRD_NRD_1	191	193	PF00675	0.310
CLV_NRD_NRD_1	217	219	PF00675	0.372
CLV_NRD_NRD_1	45	47	PF00675	0.517
CLV_PCSK_KEX2_1	101	103	PF00082	0.446
CLV_PCSK_KEX2_1	191	193	PF00082	0.310
CLV_PCSK_KEX2_1	217	219	PF00082	0.467
CLV_PCSK_KEX2_1	45	47	PF00082	0.517
CLV_PCSK_PC7_1	213	219	PF00082	0.353
CLV_PCSK_SKI1_1	84	88	PF00082	0.476
DEG_Nend_UBRbox_1	1	4	PF02207	0.539
DEG_SCF_FBW7_1	10	15	PF00400	0.516
DOC_CKS1_1	9	14	PF01111	0.517
DOC_CYCLIN_RxL_1	191	201	PF00134	0.267
DOC_MAPK_gen_1	191	199	PF00069	0.274
DOC_MAPK_gen_1	235	245	PF00069	0.284
DOC_MAPK_gen_1	250	260	PF00069	0.300
DOC_PP1_RVXF_1	190	197	PF00149	0.281
DOC_PP1_SILK_1	222	227	PF00149	0.393
DOC_PP2B_LxvP_1	30	33	PF13499	0.501
DOC_SPAK_OSR1_1	149	153	PF12202	0.238
DOC_USP7_MATH_1	12	16	PF00917	0.546
DOC_USP7_MATH_1	5	9	PF00917	0.555
DOC_USP7_MATH_1	79	83	PF00917	0.478
DOC_WW_Pin1_4	20	25	PF00397	0.649
DOC_WW_Pin1_4	8	13	PF00397	0.698
DOC_WW_Pin1_4	88	93	PF00397	0.473
LIG_14-3-3_CanoR_1	102	108	PF00244	0.218
LIG_14-3-3_CanoR_1	186	194	PF00244	0.298
LIG_14-3-3_CanoR_1	217	221	PF00244	0.431
LIG_14-3-3_CanoR_1	84	94	PF00244	0.468
LIG_Actin_WH2_2	124	141	PF00022	0.263
LIG_BIR_III_2	31	35	PF00653	0.505
LIG_FHA_1	232	238	PF00498	0.519
LIG_FHA_1	255	261	PF00498	0.259
LIG_FHA_1	264	270	PF00498	0.282
LIG_FHA_1	89	95	PF00498	0.496
LIG_FHA_2	65	71	PF00498	0.519
LIG_HCF-1_HBM_1	211	214	PF13415	0.340
LIG_MYND_1	92	96	PF01753	0.427
LIG_Pex14_2	151	155	PF04695	0.243
LIG_Pex14_2	241	245	PF04695	0.238
LIG_REV1ctd_RIR_1	148	158	PF16727	0.261
LIG_SH2_CRK	110	114	PF00017	0.315
LIG_SH2_CRK	172	176	PF00017	0.404
LIG_SH2_STAT5	130	133	PF00017	0.382
LIG_SH2_STAT5	214	217	PF00017	0.501
LIG_SH2_STAT5	236	239	PF00017	0.559
LIG_SH2_STAT5	268	271	PF00017	0.234
LIG_SH3_1	111	117	PF00018	0.324
LIG_SH3_1	21	27	PF00018	0.517
LIG_SH3_3	110	116	PF00018	0.307
LIG_SH3_3	21	27	PF00018	0.517
LIG_SH3_3	73	79	PF00018	0.502
LIG_SUMO_SIM_anti_2	255	263	PF11976	0.266
LIG_WRC_WIRS_1	274	279	PF05994	0.483
MOD_CK1_1	132	138	PF00069	0.263
MOD_CK1_1	249	255	PF00069	0.591
MOD_CK1_1	276	282	PF00069	0.246
MOD_CK1_1	57	63	PF00069	0.550
MOD_CK1_1	8	14	PF00069	0.517
MOD_CK1_1	88	94	PF00069	0.468
MOD_CK2_1	249	255	PF00069	0.332
MOD_Cter_Amidation	43	46	PF01082	0.510
MOD_GlcNHglycan	14	17	PF01048	0.523
MOD_GlcNHglycan	229	232	PF01048	0.390
MOD_GlcNHglycan	35	38	PF01048	0.510
MOD_GlcNHglycan	87	90	PF01048	0.512
MOD_GSK3_1	227	234	PF00069	0.486
MOD_GSK3_1	4	11	PF00069	0.521
MOD_GSK3_1	54	61	PF00069	0.572
MOD_GSK3_1	90	97	PF00069	0.540
MOD_N-GLC_1	186	191	PF02516	0.299
MOD_N-GLC_1	263	268	PF02516	0.281
MOD_N-GLC_1	54	59	PF02516	0.529
MOD_NEK2_2	79	84	PF00069	0.478
MOD_PIKK_1	263	269	PF00454	0.281
MOD_PIKK_1	276	282	PF00454	0.211
MOD_PIKK_1	5	11	PF00454	0.519
MOD_PKA_2	216	222	PF00069	0.434
MOD_PKA_2	249	255	PF00069	0.483
MOD_Plk_1	254	260	PF00069	0.266
MOD_Plk_1	263	269	PF00069	0.257
MOD_Plk_4	132	138	PF00069	0.281
MOD_Plk_4	173	179	PF00069	0.430
MOD_Plk_4	180	186	PF00069	0.401
MOD_Plk_4	273	279	PF00069	0.294
MOD_ProDKin_1	20	26	PF00069	0.644
MOD_ProDKin_1	8	14	PF00069	0.700
MOD_ProDKin_1	88	94	PF00069	0.462
MOD_SUMO_rev_2	201	207	PF00179	0.264
MOD_SUMO_rev_2	54	60	PF00179	0.531
TRG_DiLeu_BaEn_1	256	261	PF01217	0.250
TRG_DiLeu_BaLyEn_6	82	87	PF01217	0.479
TRG_ENDOCYTIC_2	110	113	PF00928	0.310
TRG_ER_diArg_1	100	102	PF00400	0.456
TRG_ER_diArg_1	191	193	PF00400	0.310
TRG_ER_diArg_1	45	48	PF00400	0.518

Homologs


Protein	Taxonomy	Sequence identity	Coverage
V5DLT9	Trypanosoma cruzi	39%	85%