Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q2S1_LEIMA

TriTrypDb:

LmjF.34.2740 , LMJLV39_340032800 , LMJSD75_340032900

Length:

184

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q2S1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2S1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	14	18	PF00656	0.531
CLV_NRD_NRD_1	163	165	PF00675	0.572
CLV_PCSK_SKI1_1	83	87	PF00082	0.532
DEG_SCF_FBW7_1	110	117	PF00400	0.638
DEG_SCF_FBW7_1	24	30	PF00400	0.542
DEG_SCF_FBW7_1	70	77	PF00400	0.498
DOC_CDC14_PxL_1	134	142	PF14671	0.603
DOC_CKS1_1	111	116	PF01111	0.639
DOC_CKS1_1	24	29	PF01111	0.544
DOC_PP4_FxxP_1	107	110	PF00568	0.762
DOC_PP4_FxxP_1	21	24	PF00568	0.522
DOC_USP7_MATH_1	10	14	PF00917	0.622
DOC_USP7_MATH_1	100	104	PF00917	0.516
DOC_USP7_MATH_1	148	152	PF00917	0.597
DOC_USP7_MATH_1	156	160	PF00917	0.593
DOC_USP7_MATH_1	48	52	PF00917	0.484
DOC_USP7_MATH_1	74	78	PF00917	0.545
DOC_USP7_UBL2_3	95	99	PF12436	0.519
DOC_WW_Pin1_4	102	107	PF00397	0.534
DOC_WW_Pin1_4	110	115	PF00397	0.583
DOC_WW_Pin1_4	121	126	PF00397	0.463
DOC_WW_Pin1_4	140	145	PF00397	0.488
DOC_WW_Pin1_4	146	151	PF00397	0.531
DOC_WW_Pin1_4	23	28	PF00397	0.528
DOC_WW_Pin1_4	35	40	PF00397	0.504
DOC_WW_Pin1_4	44	49	PF00397	0.480
DOC_WW_Pin1_4	59	64	PF00397	0.506
DOC_WW_Pin1_4	70	75	PF00397	0.504
LIG_BRCT_BRCA1_1	103	107	PF00533	0.481
LIG_BRCT_BRCA1_1	17	21	PF00533	0.541
LIG_DCNL_PONY_1	1	4	PF03556	0.541
LIG_EH_1	22	26	PF12763	0.450
LIG_FHA_1	60	66	PF00498	0.556
LIG_FHA_1	88	94	PF00498	0.463
LIG_FHA_2	45	51	PF00498	0.520
LIG_LIR_Apic_2	104	110	PF02991	0.581
LIG_LIR_Apic_2	18	24	PF02991	0.506
LIG_LIR_Nem_3	50	56	PF02991	0.497
LIG_NRBOX	92	98	PF00104	0.477
LIG_Pex14_2	21	25	PF04695	0.568
LIG_PTB_Apo_2	31	38	PF02174	0.438
LIG_PTB_Phospho_1	31	37	PF10480	0.439
LIG_SH2_NCK_1	56	60	PF00017	0.546
LIG_SH2_STAT5	11	14	PF00017	0.530
LIG_SH3_1	33	39	PF00018	0.506
LIG_SH3_3	176	182	PF00018	0.525
LIG_SH3_3	21	27	PF00018	0.560
LIG_SH3_3	33	39	PF00018	0.619
LIG_TRAF2_1	47	50	PF00917	0.404
LIG_UBA3_1	93	99	PF00899	0.483
MOD_CDK_SPxK_1	110	116	PF00069	0.636
MOD_CDK_SPxK_1	140	146	PF00069	0.619
MOD_CDK_SPxK_1	27	33	PF00069	0.511
MOD_CDK_SPxK_1	70	76	PF00069	0.501
MOD_CDK_SPxxK_3	146	153	PF00069	0.622
MOD_CK1_1	124	130	PF00069	0.673
MOD_CK1_1	139	145	PF00069	0.534
MOD_CK1_1	149	155	PF00069	0.593
MOD_CK1_1	15	21	PF00069	0.552
MOD_CK1_1	44	50	PF00069	0.660
MOD_CK1_1	98	104	PF00069	0.498
MOD_CK2_1	139	145	PF00069	0.591
MOD_CK2_1	44	50	PF00069	0.422
MOD_DYRK1A_RPxSP_1	146	150	PF00069	0.623
MOD_GlcNHglycan	158	161	PF01048	0.551
MOD_GlcNHglycan	174	177	PF01048	0.545
MOD_GlcNHglycan	4	7	PF01048	0.633
MOD_GSK3_1	106	113	PF00069	0.587
MOD_GSK3_1	11	18	PF00069	0.570
MOD_GSK3_1	117	124	PF00069	0.588
MOD_GSK3_1	132	139	PF00069	0.699
MOD_GSK3_1	23	30	PF00069	0.476
MOD_GSK3_1	44	51	PF00069	0.478
MOD_GSK3_1	70	77	PF00069	0.498
MOD_GSK3_1	98	105	PF00069	0.514
MOD_NEK2_1	41	46	PF00069	0.527
MOD_NEK2_2	48	53	PF00069	0.489
MOD_OFUCOSY	40	46	PF10250	0.542
MOD_PIKK_1	87	93	PF00454	0.504
MOD_PKA_2	172	178	PF00069	0.545
MOD_Plk_1	48	54	PF00069	0.490
MOD_Plk_4	124	130	PF00069	0.609
MOD_Plk_4	48	54	PF00069	0.490
MOD_ProDKin_1	102	108	PF00069	0.536
MOD_ProDKin_1	110	116	PF00069	0.585
MOD_ProDKin_1	121	127	PF00069	0.463
MOD_ProDKin_1	140	146	PF00069	0.489
MOD_ProDKin_1	23	29	PF00069	0.528
MOD_ProDKin_1	35	41	PF00069	0.505
MOD_ProDKin_1	44	50	PF00069	0.481
MOD_ProDKin_1	59	65	PF00069	0.509
MOD_ProDKin_1	70	76	PF00069	0.506
TRG_DiLeu_BaEn_1	89	94	PF01217	0.491
TRG_ENDOCYTIC_2	56	59	PF00928	0.545

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL34	Leptomonas seymouri	46%	71%
A0A3S7X828	Leishmania donovani	95%	100%
A4IA50	Leishmania infantum	95%	100%
E9B564	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%