Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q2Q8_LEIMA

TriTrypDb:

LmjF.34.2860 , LMJLV39_340034100 , LMJSD75_340034300

Length:

118


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	12
GO:0032991	protein-containing complex	1	12
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12
GO:1990904	ribonucleoprotein complex	2	12

Q4Q2Q8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2Q8

PDB structure(s): 7aih_U , 7ane_U


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	59	63	PF00656	0.428
CLV_NRD_NRD_1	31	33	PF00675	0.521
CLV_NRD_NRD_1	65	67	PF00675	0.410
CLV_NRD_NRD_1	99	101	PF00675	0.466
CLV_PCSK_KEX2_1	20	22	PF00082	0.516
CLV_PCSK_PC1ET2_1	20	22	PF00082	0.516
DEG_Nend_Nbox_1	1	3	PF02207	0.482
DOC_MAPK_gen_1	17	25	PF00069	0.477
DOC_MAPK_gen_1	32	41	PF00069	0.378
DOC_MAPK_RevD_3	104	118	PF00069	0.424
DOC_PP1_RVXF_1	19	26	PF00149	0.456
DOC_PP1_RVXF_1	98	105	PF00149	0.409
DOC_USP7_MATH_1	40	44	PF00917	0.320
DOC_USP7_UBL2_3	113	117	PF12436	0.587
DOC_USP7_UBL2_3	15	19	PF12436	0.462
LIG_14-3-3_CanoR_1	3	9	PF00244	0.489
LIG_14-3-3_CanoR_1	79	83	PF00244	0.415
LIG_BIR_III_4	62	66	PF00653	0.440
LIG_FHA_2	54	60	PF00498	0.383
LIG_FHA_2	69	75	PF00498	0.469
LIG_LIR_Nem_3	71	76	PF02991	0.335
LIG_SH2_STAT5	53	56	PF00017	0.375
LIG_SH2_STAT5	80	83	PF00017	0.405
LIG_SH3_3	85	91	PF00018	0.481
LIG_SH3_3	99	105	PF00018	0.346
LIG_SUMO_SIM_par_1	37	44	PF11976	0.337
MOD_CK2_1	53	59	PF00069	0.375
MOD_Cter_Amidation	115	118	PF01082	0.617
MOD_Cter_Amidation	64	67	PF01082	0.409
MOD_GSK3_1	40	47	PF00069	0.329
MOD_NEK2_1	109	114	PF00069	0.506
MOD_NEK2_1	2	7	PF00069	0.463
MOD_NEK2_1	61	66	PF00069	0.428
MOD_NEK2_1	68	73	PF00069	0.344
MOD_NEK2_1	83	88	PF00069	0.286
MOD_NEK2_1	93	98	PF00069	0.353
MOD_PKA_2	2	8	PF00069	0.491
MOD_PKA_2	78	84	PF00069	0.422
MOD_Plk_4	4	10	PF00069	0.429
MOD_Plk_4	68	74	PF00069	0.559
MOD_Plk_4	78	84	PF00069	0.521
MOD_SUMO_for_1	54	57	PF00179	0.382
TRG_ENDOCYTIC_2	80	83	PF00928	0.380
TRG_NLS_Bipartite_1	19	36	PF00514	0.461
TRG_NLS_MonoExtN_4	17	23	PF00514	0.513
TRG_NLS_MonoExtN_4	31	36	PF00514	0.592


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2X7	Leptomonas seymouri	86%	100%
A0A0S4IY48	Bodo saltans	71%	100%
A0A1X0PA43	Trypanosomatidae	84%	100%
A0A3R7NLI3	Trypanosoma rangeli	79%	100%
A0A3S7X845	Leishmania donovani	94%	100%
A4HB08	Leishmania braziliensis	92%	100%
A4IA65	Leishmania infantum	94%	100%
C9ZM42	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	81%	100%
E9B577	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
V5BKZ6	Trypanosoma cruzi	81%	100%