Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q2Q2_LEIMA

TriTrypDb:

LmjF.34.2920 , LMJLV39_340034500 , LMJSD75_340034800

Length:

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Show entries

Cellular components
Term	Name	Level	Count
GO:0005783	endoplasmic reticulum	5	2
GO:0016020	membrane	2	8
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	8

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Expansion

Sequence features

Q4Q2Q2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2Q2

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	6	8	PF00675	0.427
CLV_NRD_NRD_1	75	77	PF00675	0.672
CLV_PCSK_KEX2_1	6	8	PF00082	0.427
CLV_PCSK_KEX2_1	75	77	PF00082	0.613
CLV_PCSK_SKI1_1	14	18	PF00082	0.382
CLV_PCSK_SKI1_1	46	50	PF00082	0.369
CLV_PCSK_SKI1_1	6	10	PF00082	0.396
DEG_Nend_Nbox_1	1	3	PF02207	0.627
DEG_SCF_FBW7_2	65	72	PF00400	0.612
DOC_CKS1_1	66	71	PF01111	0.447

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5F0	Leptomonas seymouri	71%	100%
A0A0S4J4S3	Bodo saltans	53%	100%
A0A3Q8INJ8	Leishmania donovani	92%	100%
A4HB11	Leishmania braziliensis	84%	100%
A4IA68	Leishmania infantum	91%	100%
C9ZM38	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
E9B581	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%

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