LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Phospholipid-transporting ATPase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Phospholipid-transporting ATPase
Gene product:
aminophospholipid translocase, putative
Species:
Leishmania major
UniProt:
Q4Q2M2_LEIMA
TriTrypDb:
LmjF.34.3220 , LMJLV39_340037900 , LMJSD75_340038200 *
Length:
1157

Annotations

LeishMANIAdb annotations

Homologous to endosomal / ER-localized phospholipid flippases of other Eukaryotes.. These genes only duplicated in Trypasoma conorini and Trypansoma cruzi. Localization: ER (by homology) / Endosomal (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005768 endosome 7 2
GO:0005802 trans-Golgi network 4 2
GO:0005886 plasma membrane 3 2
GO:0016020 membrane 2 11
GO:0031410 cytoplasmic vesicle 6 2
GO:0031982 vesicle 4 2
GO:0031984 organelle subcompartment 2 2
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043231 intracellular membrane-bounded organelle 4 2
GO:0097708 intracellular vesicle 5 2
GO:0098791 Golgi apparatus subcompartment 3 2
GO:0110165 cellular anatomical entity 1 11

Expansion

Sequence features

Q4Q2M2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2M2

Function

Biological processes
Term Name Level Count
GO:0006810 transport 3 11
GO:0006869 lipid transport 5 11
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 6 2
GO:0006897 endocytosis 5 2
GO:0009987 cellular process 1 2
GO:0015748 organophosphate ester transport 5 11
GO:0015914 phospholipid transport 6 11
GO:0016043 cellular component organization 3 2
GO:0016192 vesicle-mediated transport 4 2
GO:0034204 lipid translocation 4 2
GO:0045332 phospholipid translocation 5 2
GO:0048193 Golgi vesicle transport 5 2
GO:0051179 localization 1 11
GO:0051234 establishment of localization 2 11
GO:0061024 membrane organization 4 2
GO:0065007 biological regulation 1 2
GO:0065008 regulation of biological quality 2 2
GO:0071702 organic substance transport 4 11
GO:0071840 cellular component organization or biogenesis 2 2
GO:0097035 regulation of membrane lipid distribution 3 2
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 11
GO:0000287 magnesium ion binding 5 11
GO:0003824 catalytic activity 1 11
GO:0005215 transporter activity 1 11
GO:0005319 lipid transporter activity 2 11
GO:0005488 binding 1 11
GO:0005524 ATP binding 5 11
GO:0016462 pyrophosphatase activity 5 11
GO:0016787 hydrolase activity 2 11
GO:0016817 hydrolase activity, acting on acid anhydrides 3 11
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 11
GO:0016887 ATP hydrolysis activity 7 11
GO:0017076 purine nucleotide binding 4 11
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 11
GO:0030554 adenyl nucleotide binding 5 11
GO:0032553 ribonucleotide binding 3 11
GO:0032555 purine ribonucleotide binding 4 11
GO:0032559 adenyl ribonucleotide binding 5 11
GO:0035639 purine ribonucleoside triphosphate binding 4 11
GO:0036094 small molecule binding 2 11
GO:0043167 ion binding 2 11
GO:0043168 anion binding 3 11
GO:0043169 cation binding 3 11
GO:0046872 metal ion binding 4 11
GO:0097159 organic cyclic compound binding 2 11
GO:0097367 carbohydrate derivative binding 2 11
GO:0140303 intramembrane lipid transporter activity 3 11
GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2 11
GO:0140657 ATP-dependent activity 1 11
GO:1901265 nucleoside phosphate binding 3 11
GO:1901363 heterocyclic compound binding 2 11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 247 251 PF00656 0.447
CLV_C14_Caspase3-7 870 874 PF00656 0.630
CLV_NRD_NRD_1 1078 1080 PF00675 0.248
CLV_NRD_NRD_1 117 119 PF00675 0.258
CLV_NRD_NRD_1 185 187 PF00675 0.337
CLV_NRD_NRD_1 2 4 PF00675 0.530
CLV_NRD_NRD_1 624 626 PF00675 0.248
CLV_NRD_NRD_1 75 77 PF00675 0.418
CLV_NRD_NRD_1 799 801 PF00675 0.321
CLV_PCSK_FUR_1 1076 1080 PF00082 0.334
CLV_PCSK_FUR_1 183 187 PF00082 0.352
CLV_PCSK_FUR_1 343 347 PF00082 0.206
CLV_PCSK_KEX2_1 1078 1080 PF00082 0.247
CLV_PCSK_KEX2_1 117 119 PF00082 0.258
CLV_PCSK_KEX2_1 182 184 PF00082 0.330
CLV_PCSK_KEX2_1 185 187 PF00082 0.319
CLV_PCSK_KEX2_1 2 4 PF00082 0.530
CLV_PCSK_KEX2_1 345 347 PF00082 0.206
CLV_PCSK_KEX2_1 75 77 PF00082 0.398
CLV_PCSK_KEX2_1 799 801 PF00082 0.321
CLV_PCSK_PC1ET2_1 182 184 PF00082 0.358
CLV_PCSK_PC1ET2_1 345 347 PF00082 0.206
CLV_PCSK_SKI1_1 1007 1011 PF00082 0.253
CLV_PCSK_SKI1_1 1018 1022 PF00082 0.235
CLV_PCSK_SKI1_1 1081 1085 PF00082 0.334
CLV_PCSK_SKI1_1 1109 1113 PF00082 0.472
CLV_PCSK_SKI1_1 1140 1144 PF00082 0.308
CLV_PCSK_SKI1_1 175 179 PF00082 0.361
CLV_PCSK_SKI1_1 334 338 PF00082 0.334
CLV_PCSK_SKI1_1 439 443 PF00082 0.382
CLV_PCSK_SKI1_1 493 497 PF00082 0.525
CLV_PCSK_SKI1_1 595 599 PF00082 0.308
CLV_PCSK_SKI1_1 79 83 PF00082 0.432
CLV_TASPASE1 248 254 PF01112 0.447
DEG_APCC_DBOX_1 1017 1025 PF00400 0.472
DEG_APCC_DBOX_1 74 82 PF00400 0.634
DEG_Nend_UBRbox_1 1 4 PF02207 0.750
DEG_ODPH_VHL_1 86 97 PF01847 0.620
DEG_SPOP_SBC_1 28 32 PF00917 0.621
DOC_ANK_TNKS_1 874 881 PF00023 0.478
DOC_CYCLIN_RxL_1 436 446 PF00134 0.580
DOC_CYCLIN_yClb5_NLxxxL_5 427 435 PF00134 0.592
DOC_MAPK_gen_1 1076 1086 PF00069 0.460
DOC_MAPK_gen_1 185 194 PF00069 0.605
DOC_MAPK_gen_1 45 52 PF00069 0.620
DOC_MAPK_gen_1 453 461 PF00069 0.607
DOC_MAPK_gen_1 583 592 PF00069 0.553
DOC_MAPK_gen_1 625 632 PF00069 0.447
DOC_MAPK_gen_1 75 86 PF00069 0.593
DOC_MAPK_MEF2A_6 583 592 PF00069 0.472
DOC_MAPK_MEF2A_6 625 632 PF00069 0.447
DOC_MAPK_MEF2A_6 79 86 PF00069 0.608
DOC_MAPK_MEF2A_6 916 925 PF00069 0.458
DOC_MAPK_NFAT4_5 79 87 PF00069 0.635
DOC_PP1_RVXF_1 1070 1076 PF00149 0.450
DOC_PP1_RVXF_1 1138 1145 PF00149 0.534
DOC_PP1_RVXF_1 152 158 PF00149 0.258
DOC_PP1_RVXF_1 491 497 PF00149 0.610
DOC_PP1_RVXF_1 680 687 PF00149 0.479
DOC_PP1_RVXF_1 920 927 PF00149 0.447
DOC_PP2B_LxvP_1 64 67 PF13499 0.577
DOC_PP2B_PxIxI_1 163 169 PF00149 0.242
DOC_SPAK_OSR1_1 276 280 PF12202 0.549
DOC_SPAK_OSR1_1 387 391 PF12202 0.447
DOC_USP7_MATH_1 1053 1057 PF00917 0.315
DOC_USP7_MATH_1 260 264 PF00917 0.549
DOC_USP7_MATH_1 336 340 PF00917 0.486
DOC_USP7_MATH_1 550 554 PF00917 0.717
DOC_USP7_MATH_1 59 63 PF00917 0.704
DOC_USP7_MATH_1 620 624 PF00917 0.447
DOC_USP7_MATH_1 8 12 PF00917 0.623
DOC_USP7_UBL2_3 1007 1011 PF12436 0.447
DOC_USP7_UBL2_3 451 455 PF12436 0.612
DOC_USP7_UBL2_3 649 653 PF12436 0.461
DOC_WW_Pin1_4 102 107 PF00397 0.607
DOC_WW_Pin1_4 160 165 PF00397 0.334
DOC_WW_Pin1_4 22 27 PF00397 0.758
DOC_WW_Pin1_4 338 343 PF00397 0.549
DOC_WW_Pin1_4 529 534 PF00397 0.493
DOC_WW_Pin1_4 572 577 PF00397 0.455
DOC_WW_Pin1_4 853 858 PF00397 0.509
DOC_WW_Pin1_4 86 91 PF00397 0.636
LIG_14-3-3_CanoR_1 117 122 PF00244 0.459
LIG_14-3-3_CanoR_1 19 29 PF00244 0.769
LIG_14-3-3_CanoR_1 408 414 PF00244 0.499
LIG_14-3-3_CanoR_1 439 449 PF00244 0.557
LIG_14-3-3_CanoR_1 502 506 PF00244 0.725
LIG_14-3-3_CanoR_1 689 696 PF00244 0.527
LIG_14-3-3_CanoR_1 845 851 PF00244 0.539
LIG_14-3-3_CanoR_1 929 933 PF00244 0.447
LIG_14-3-3_CanoR_1 937 943 PF00244 0.447
LIG_APCC_ABBA_1 218 223 PF00400 0.534
LIG_BRCT_BRCA1_1 1043 1047 PF00533 0.349
LIG_BRCT_BRCA1_1 598 602 PF00533 0.452
LIG_BRCT_BRCA1_1 956 960 PF00533 0.299
LIG_BRCT_BRCA1_1 976 980 PF00533 0.117
LIG_Clathr_ClatBox_1 49 53 PF01394 0.621
LIG_CtBP_PxDLS_1 397 401 PF00389 0.447
LIG_CtBP_PxDLS_1 432 436 PF00389 0.480
LIG_deltaCOP1_diTrp_1 179 184 PF00928 0.594
LIG_FHA_1 1053 1059 PF00498 0.314
LIG_FHA_1 1066 1072 PF00498 0.299
LIG_FHA_1 23 29 PF00498 0.759
LIG_FHA_1 239 245 PF00498 0.452
LIG_FHA_1 262 268 PF00498 0.469
LIG_FHA_1 292 298 PF00498 0.513
LIG_FHA_1 317 323 PF00498 0.510
LIG_FHA_1 444 450 PF00498 0.477
LIG_FHA_1 470 476 PF00498 0.650
LIG_FHA_1 610 616 PF00498 0.534
LIG_FHA_1 725 731 PF00498 0.596
LIG_FHA_1 775 781 PF00498 0.493
LIG_FHA_1 820 826 PF00498 0.483
LIG_FHA_1 90 96 PF00498 0.473
LIG_FHA_1 933 939 PF00498 0.534
LIG_FHA_1 962 968 PF00498 0.258
LIG_FHA_2 327 333 PF00498 0.447
LIG_FHA_2 541 547 PF00498 0.736
LIG_FHA_2 591 597 PF00498 0.488
LIG_FHA_2 688 694 PF00498 0.546
LIG_FHA_2 733 739 PF00498 0.482
LIG_GBD_Chelix_1 1090 1098 PF00786 0.427
LIG_Integrin_RGD_1 378 380 PF01839 0.334
LIG_LIR_Apic_2 160 164 PF02991 0.315
LIG_LIR_Gen_1 1044 1054 PF02991 0.260
LIG_LIR_Gen_1 266 277 PF02991 0.511
LIG_LIR_Gen_1 368 377 PF02991 0.467
LIG_LIR_Gen_1 380 389 PF02991 0.413
LIG_LIR_Gen_1 612 621 PF02991 0.419
LIG_LIR_Gen_1 838 848 PF02991 0.503
LIG_LIR_Gen_1 954 961 PF02991 0.420
LIG_LIR_LC3C_4 319 324 PF02991 0.549
LIG_LIR_Nem_3 1001 1005 PF02991 0.473
LIG_LIR_Nem_3 103 107 PF02991 0.635
LIG_LIR_Nem_3 1044 1050 PF02991 0.274
LIG_LIR_Nem_3 1051 1057 PF02991 0.347
LIG_LIR_Nem_3 1116 1121 PF02991 0.266
LIG_LIR_Nem_3 122 127 PF02991 0.450
LIG_LIR_Nem_3 160 165 PF02991 0.334
LIG_LIR_Nem_3 179 184 PF02991 0.577
LIG_LIR_Nem_3 193 198 PF02991 0.482
LIG_LIR_Nem_3 266 272 PF02991 0.511
LIG_LIR_Nem_3 368 372 PF02991 0.489
LIG_LIR_Nem_3 593 597 PF02991 0.507
LIG_LIR_Nem_3 612 616 PF02991 0.419
LIG_LIR_Nem_3 838 843 PF02991 0.499
LIG_LIR_Nem_3 846 851 PF02991 0.497
LIG_LIR_Nem_3 954 959 PF02991 0.357
LIG_LIR_Nem_3 966 971 PF02991 0.198
LIG_LYPXL_yS_3 1002 1005 PF13949 0.534
LIG_NRBOX 366 372 PF00104 0.531
LIG_NRBOX 77 83 PF00104 0.598
LIG_PCNA_yPIPBox_3 401 410 PF02747 0.494
LIG_PCNA_yPIPBox_3 678 689 PF02747 0.490
LIG_Pex14_1 1025 1029 PF04695 0.299
LIG_Pex14_1 255 259 PF04695 0.447
LIG_Pex14_2 100 104 PF04695 0.640
LIG_Pex14_2 1107 1111 PF04695 0.283
LIG_Pex14_2 133 137 PF04695 0.438
LIG_Pex14_2 139 143 PF04695 0.287
LIG_Pex14_2 377 381 PF04695 0.472
LIG_Pex14_2 385 389 PF04695 0.467
LIG_Pex14_2 956 960 PF04695 0.315
LIG_PTB_Apo_2 113 120 PF02174 0.458
LIG_PTB_Apo_2 135 142 PF02174 0.291
LIG_PTB_Phospho_1 113 119 PF10480 0.458
LIG_PTB_Phospho_1 135 141 PF10480 0.315
LIG_SH2_CRK 1054 1058 PF00017 0.315
LIG_SH2_CRK 6 10 PF00017 0.746
LIG_SH2_CRK 613 617 PF00017 0.400
LIG_SH2_CRK 848 852 PF00017 0.483
LIG_SH2_CRK 949 953 PF00017 0.299
LIG_SH2_CRK 976 980 PF00017 0.315
LIG_SH2_NCK_1 949 953 PF00017 0.299
LIG_SH2_NCK_1 976 980 PF00017 0.299
LIG_SH2_STAP1 1054 1058 PF00017 0.315
LIG_SH2_STAP1 269 273 PF00017 0.442
LIG_SH2_STAP1 411 415 PF00017 0.473
LIG_SH2_STAP1 703 707 PF00017 0.606
LIG_SH2_STAP1 848 852 PF00017 0.483
LIG_SH2_STAP1 976 980 PF00017 0.315
LIG_SH2_STAT5 1054 1057 PF00017 0.332
LIG_SH2_STAT5 1141 1144 PF00017 0.584
LIG_SH2_STAT5 119 122 PF00017 0.317
LIG_SH2_STAT5 141 144 PF00017 0.315
LIG_SH2_STAT5 161 164 PF00017 0.287
LIG_SH2_STAT5 269 272 PF00017 0.406
LIG_SH2_STAT5 328 331 PF00017 0.508
LIG_SH2_STAT5 440 443 PF00017 0.463
LIG_SH2_STAT5 482 485 PF00017 0.604
LIG_SH2_STAT5 613 616 PF00017 0.496
LIG_SH2_STAT5 788 791 PF00017 0.553
LIG_SH2_STAT5 832 835 PF00017 0.568
LIG_SH2_STAT5 971 974 PF00017 0.299
LIG_SH2_STAT5 99 102 PF00017 0.648
LIG_SH3_3 104 110 PF00018 0.589
LIG_SH3_3 1098 1104 PF00018 0.420
LIG_SH3_3 33 39 PF00018 0.751
LIG_SH3_3 416 422 PF00018 0.617
LIG_SH3_3 532 538 PF00018 0.549
LIG_SUMO_SIM_anti_2 1060 1066 PF11976 0.299
LIG_SUMO_SIM_anti_2 1088 1095 PF11976 0.420
LIG_SUMO_SIM_anti_2 163 169 PF11976 0.270
LIG_SUMO_SIM_anti_2 216 221 PF11976 0.454
LIG_SUMO_SIM_anti_2 48 54 PF11976 0.620
LIG_SUMO_SIM_anti_2 577 583 PF11976 0.534
LIG_SUMO_SIM_par_1 1099 1106 PF11976 0.299
LIG_SUMO_SIM_par_1 203 209 PF11976 0.543
LIG_SUMO_SIM_par_1 362 368 PF11976 0.470
LIG_SUMO_SIM_par_1 48 54 PF11976 0.620
LIG_SUMO_SIM_par_1 532 537 PF11976 0.619
LIG_SUMO_SIM_par_1 821 826 PF11976 0.458
LIG_SxIP_EBH_1 389 401 PF03271 0.534
LIG_TRAF2_1 13 16 PF00917 0.739
LIG_TRAF2_1 478 481 PF00917 0.628
LIG_TRAF2_1 643 646 PF00917 0.529
LIG_TYR_ITIM 1052 1057 PF00017 0.315
LIG_TYR_ITIM 267 272 PF00017 0.420
LIG_TYR_ITIM 4 9 PF00017 0.711
LIG_TYR_ITIM 592 597 PF00017 0.420
LIG_TYR_ITIM 947 952 PF00017 0.385
LIG_TYR_ITSM 844 851 PF00017 0.400
LIG_UBA3_1 1035 1043 PF00899 0.442
LIG_UBA3_1 1133 1140 PF00899 0.442
LIG_Vh1_VBS_1 1084 1102 PF01044 0.442
LIG_WRC_WIRS_1 121 126 PF05994 0.299
LIG_WRC_WIRS_1 288 293 PF05994 0.407
LIG_WRC_WIRS_1 366 371 PF05994 0.385
MOD_CDK_SPK_2 338 343 PF00069 0.442
MOD_CDK_SPxxK_3 338 345 PF00069 0.442
MOD_CDK_SPxxK_3 853 860 PF00069 0.377
MOD_CDK_SPxxK_3 86 93 PF00069 0.413
MOD_CK1_1 1014 1020 PF00069 0.357
MOD_CK1_1 20 26 PF00069 0.687
MOD_CK1_1 236 242 PF00069 0.338
MOD_CK1_1 263 269 PF00069 0.412
MOD_CK1_1 443 449 PF00069 0.425
MOD_CK1_1 54 60 PF00069 0.619
MOD_CK1_1 566 572 PF00069 0.631
MOD_CK1_1 62 68 PF00069 0.534
MOD_CK1_1 640 646 PF00069 0.428
MOD_CK1_1 835 841 PF00069 0.490
MOD_CK1_1 89 95 PF00069 0.537
MOD_CK2_1 326 332 PF00069 0.420
MOD_CK2_1 540 546 PF00069 0.704
MOD_CK2_1 572 578 PF00069 0.286
MOD_CK2_1 640 646 PF00069 0.428
MOD_CK2_1 687 693 PF00069 0.510
MOD_CK2_1 732 738 PF00069 0.359
MOD_CMANNOS 1115 1118 PF00535 0.357
MOD_Cter_Amidation 797 800 PF01082 0.437
MOD_GlcNHglycan 10 13 PF01048 0.687
MOD_GlcNHglycan 208 211 PF01048 0.313
MOD_GlcNHglycan 237 241 PF01048 0.352
MOD_GlcNHglycan 31 34 PF01048 0.720
MOD_GlcNHglycan 334 337 PF01048 0.379
MOD_GlcNHglycan 499 502 PF01048 0.621
MOD_GlcNHglycan 552 555 PF01048 0.735
MOD_GlcNHglycan 639 642 PF01048 0.424
MOD_GSK3_1 1048 1055 PF00069 0.306
MOD_GSK3_1 108 115 PF00069 0.432
MOD_GSK3_1 1085 1092 PF00069 0.413
MOD_GSK3_1 17 24 PF00069 0.711
MOD_GSK3_1 232 239 PF00069 0.321
MOD_GSK3_1 263 270 PF00069 0.285
MOD_GSK3_1 287 294 PF00069 0.361
MOD_GSK3_1 326 333 PF00069 0.324
MOD_GSK3_1 409 416 PF00069 0.467
MOD_GSK3_1 443 450 PF00069 0.345
MOD_GSK3_1 465 472 PF00069 0.552
MOD_GSK3_1 497 504 PF00069 0.662
MOD_GSK3_1 505 512 PF00069 0.613
MOD_GSK3_1 540 547 PF00069 0.721
MOD_GSK3_1 558 565 PF00069 0.757
MOD_GSK3_1 596 603 PF00069 0.336
MOD_GSK3_1 611 618 PF00069 0.245
MOD_GSK3_1 640 647 PF00069 0.352
MOD_GSK3_1 685 692 PF00069 0.470
MOD_GSK3_1 769 776 PF00069 0.396
MOD_GSK3_1 832 839 PF00069 0.337
MOD_GSK3_1 928 935 PF00069 0.299
MOD_GSK3_1 947 954 PF00069 0.299
MOD_GSK3_1 974 981 PF00069 0.315
MOD_N-GLC_1 21 26 PF02516 0.740
MOD_N-GLC_1 261 266 PF02516 0.381
MOD_N-GLC_1 337 342 PF02516 0.315
MOD_N-GLC_1 497 502 PF02516 0.702
MOD_N-GLC_1 529 534 PF02516 0.379
MOD_N-GLC_1 544 549 PF02516 0.587
MOD_N-GLC_1 994 999 PF02516 0.442
MOD_NEK2_1 1111 1116 PF00069 0.303
MOD_NEK2_1 144 149 PF00069 0.313
MOD_NEK2_1 157 162 PF00069 0.306
MOD_NEK2_1 261 266 PF00069 0.315
MOD_NEK2_1 29 34 PF00069 0.717
MOD_NEK2_1 337 342 PF00069 0.315
MOD_NEK2_1 365 370 PF00069 0.361
MOD_NEK2_1 391 396 PF00069 0.437
MOD_NEK2_1 505 510 PF00069 0.543
MOD_NEK2_1 584 589 PF00069 0.312
MOD_NEK2_1 729 734 PF00069 0.470
MOD_NEK2_1 867 872 PF00069 0.530
MOD_NEK2_1 912 917 PF00069 0.315
MOD_NEK2_1 960 965 PF00069 0.347
MOD_NEK2_1 974 979 PF00069 0.299
MOD_NEK2_2 501 506 PF00069 0.688
MOD_NEK2_2 644 649 PF00069 0.389
MOD_NEK2_2 932 937 PF00069 0.315
MOD_NEK2_2 975 980 PF00069 0.299
MOD_OFUCOSY 809 814 PF10250 0.609
MOD_PIKK_1 144 150 PF00454 0.299
MOD_PIKK_1 855 861 PF00454 0.383
MOD_PIKK_1 936 942 PF00454 0.315
MOD_PK_1 658 664 PF00069 0.466
MOD_PKA_1 117 123 PF00069 0.315
MOD_PKA_1 70 76 PF00069 0.512
MOD_PKA_2 117 123 PF00069 0.300
MOD_PKA_2 330 336 PF00069 0.413
MOD_PKA_2 469 475 PF00069 0.554
MOD_PKA_2 501 507 PF00069 0.686
MOD_PKA_2 663 669 PF00069 0.415
MOD_PKA_2 774 780 PF00069 0.378
MOD_PKA_2 867 873 PF00069 0.541
MOD_PKA_2 928 934 PF00069 0.299
MOD_PKA_2 936 942 PF00069 0.299
MOD_PKB_1 633 641 PF00069 0.420
MOD_Plk_1 595 601 PF00069 0.388
MOD_Plk_1 884 890 PF00069 0.400
MOD_Plk_1 910 916 PF00069 0.299
MOD_Plk_2-3 303 309 PF00069 0.334
MOD_Plk_4 1024 1030 PF00069 0.334
MOD_Plk_4 1053 1059 PF00069 0.299
MOD_Plk_4 1089 1095 PF00069 0.339
MOD_Plk_4 120 126 PF00069 0.301
MOD_Plk_4 169 175 PF00069 0.315
MOD_Plk_4 239 245 PF00069 0.420
MOD_Plk_4 318 324 PF00069 0.366
MOD_Plk_4 365 371 PF00069 0.354
MOD_Plk_4 391 397 PF00069 0.400
MOD_Plk_4 462 468 PF00069 0.414
MOD_Plk_4 59 65 PF00069 0.610
MOD_Plk_4 611 617 PF00069 0.410
MOD_Plk_4 658 664 PF00069 0.415
MOD_Plk_4 705 711 PF00069 0.459
MOD_Plk_4 813 819 PF00069 0.625
MOD_Plk_4 846 852 PF00069 0.318
MOD_Plk_4 862 868 PF00069 0.371
MOD_Plk_4 884 890 PF00069 0.384
MOD_Plk_4 947 953 PF00069 0.296
MOD_Plk_4 963 969 PF00069 0.311
MOD_Plk_4 975 981 PF00069 0.299
MOD_ProDKin_1 102 108 PF00069 0.520
MOD_ProDKin_1 160 166 PF00069 0.334
MOD_ProDKin_1 22 28 PF00069 0.736
MOD_ProDKin_1 338 344 PF00069 0.442
MOD_ProDKin_1 529 535 PF00069 0.374
MOD_ProDKin_1 572 578 PF00069 0.311
MOD_ProDKin_1 853 859 PF00069 0.382
MOD_ProDKin_1 86 92 PF00069 0.563
MOD_SUMO_rev_2 176 184 PF00179 0.457
MOD_SUMO_rev_2 250 257 PF00179 0.299
MOD_SUMO_rev_2 622 628 PF00179 0.319
MOD_SUMO_rev_2 899 906 PF00179 0.416
TRG_DiLeu_BaEn_1 1089 1094 PF01217 0.420
TRG_DiLeu_BaEn_4 433 439 PF01217 0.359
TRG_DiLeu_BaLyEn_6 161 166 PF01217 0.367
TRG_DiLeu_BaLyEn_6 775 780 PF01217 0.379
TRG_DiLeu_BaLyEn_6 919 924 PF01217 0.299
TRG_ENDOCYTIC_2 1002 1005 PF00928 0.315
TRG_ENDOCYTIC_2 1006 1009 PF00928 0.282
TRG_ENDOCYTIC_2 1054 1057 PF00928 0.332
TRG_ENDOCYTIC_2 1141 1144 PF00928 0.521
TRG_ENDOCYTIC_2 141 144 PF00928 0.315
TRG_ENDOCYTIC_2 269 272 PF00928 0.403
TRG_ENDOCYTIC_2 594 597 PF00928 0.420
TRG_ENDOCYTIC_2 6 9 PF00928 0.718
TRG_ENDOCYTIC_2 613 616 PF00928 0.220
TRG_ENDOCYTIC_2 848 851 PF00928 0.367
TRG_ENDOCYTIC_2 949 952 PF00928 0.299
TRG_ENDOCYTIC_2 971 974 PF00928 0.311
TRG_ENDOCYTIC_2 976 979 PF00928 0.315
TRG_ER_diArg_1 1 3 PF00400 0.710
TRG_ER_diArg_1 1078 1081 PF00400 0.357
TRG_ER_diArg_1 117 119 PF00400 0.334
TRG_ER_diArg_1 184 186 PF00400 0.441
TRG_ER_diArg_1 437 440 PF00400 0.497
TRG_ER_diArg_1 74 76 PF00400 0.572
TRG_ER_diArg_1 799 801 PF00400 0.402
TRG_NES_CRM1_1 287 301 PF08389 0.393
TRG_NLS_MonoExtC_3 181 186 PF00514 0.487
TRG_Pf-PMV_PEXEL_1 1072 1077 PF00026 0.315
TRG_Pf-PMV_PEXEL_1 346 350 PF00026 0.242
TRG_Pf-PMV_PEXEL_1 439 444 PF00026 0.486
TRG_Pf-PMV_PEXEL_1 689 693 PF00026 0.389
TRG_Pf-PMV_PEXEL_1 76 80 PF00026 0.551
TRG_Pf-PMV_PEXEL_1 799 803 PF00026 0.410

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P450 Leptomonas seymouri 74% 98%
A0A0N1I0X4 Leptomonas seymouri 30% 100%
A0A0N1PF54 Leptomonas seymouri 26% 89%
A0A0S4IM76 Bodo saltans 54% 100%
A0A0S4ITW3 Bodo saltans 26% 84%
A0A0S4J0T6 Bodo saltans 28% 90%
A0A0S4JDQ9 Bodo saltans 29% 100%
A0A0S4JP22 Bodo saltans 30% 93%
A0A0S4JUG6 Bodo saltans 29% 100%
A0A1X0NJY2 Trypanosomatidae 29% 100%
A0A1X0PAR5 Trypanosomatidae 58% 100%
A0A3Q8IFQ5 Leishmania donovani 27% 90%
A0A3Q8INM6 Leishmania donovani 94% 100%
A0A3R7P4C4 Trypanosoma rangeli 29% 100%
A0A422NNI9 Trypanosoma rangeli 57% 100%
A1A4J6 Bos taurus 41% 100%
A3FIN4 Mus musculus 28% 98%
A4H7E2 Leishmania braziliensis 30% 100%
A4H7E4 Leishmania braziliensis 30% 100%
A4HIF8 Leishmania braziliensis 26% 93%
A4HVT2 Leishmania infantum 30% 100%
A4I5Q4 Leishmania infantum 27% 90%
A4IA89 Leishmania infantum 94% 100%
C7EXK4 Bos taurus 30% 100%
C9ZM06 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 55% 100%
D0A6F9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
D4AA47 Rattus norvegicus 27% 92%
D4ABB8 Rattus norvegicus 41% 100%
E9APH7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 100%
E9B0Z9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 90%
E9B5B1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
F1Q4S1 Danio rerio 42% 100%
G5EBH1 Caenorhabditis elegans 40% 100%
J9VQQ3 Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) 22% 82%
O36028 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 28% 85%
O43520 Homo sapiens 27% 92%
O43861 Homo sapiens 41% 100%
O70228 Mus musculus 40% 100%
O75110 Homo sapiens 41% 100%
O94296 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 29% 92%
P32660 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 29% 74%
P39524 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 29% 85%
P40527 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 37% 100%
P57792 Arabidopsis thaliana 28% 98%
P70704 Mus musculus 29% 99%
P98195 Mus musculus 41% 100%
P98196 Homo sapiens 27% 100%
P98197 Mus musculus 27% 97%
P98198 Homo sapiens 28% 96%
P98199 Mus musculus 28% 96%
P98200 Mus musculus 30% 100%
P98204 Arabidopsis thaliana 28% 100%
P98205 Arabidopsis thaliana 30% 100%
Q09891 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 27% 83%
Q10309 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 37% 100%
Q12675 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 27% 72%
Q148W0 Mus musculus 27% 92%
Q29449 Bos taurus 29% 100%
Q4Q767 Leishmania major 27% 90%
Q4QG01 Leishmania major 30% 100%
Q5BL50 Xenopus tropicalis 29% 93%
Q6DFW5 Mus musculus 28% 98%
Q6VXY9 Leishmania donovani 30% 100%
Q8NB49 Homo sapiens 27% 100%
Q8TF62 Homo sapiens 29% 97%
Q9LI83 Arabidopsis thaliana 28% 96%
Q9LK90 Arabidopsis thaliana 28% 97%
Q9LNQ4 Arabidopsis thaliana 28% 95%
Q9LVK9 Arabidopsis thaliana 28% 93%
Q9N0Z4 Oryctolagus cuniculus 28% 99%
Q9NTI2 Homo sapiens 30% 97%
Q9QZW0 Mus musculus 27% 100%
Q9SAF5 Arabidopsis thaliana 27% 96%
Q9SGG3 Arabidopsis thaliana 27% 94%
Q9SLK6 Arabidopsis thaliana 29% 93%
Q9SX33 Arabidopsis thaliana 27% 96%
Q9U280 Caenorhabditis elegans 27% 100%
Q9XIE6 Arabidopsis thaliana 29% 95%
Q9Y2G3 Homo sapiens 28% 98%
Q9Y2Q0 Homo sapiens 28% 99%
V5BHI7 Trypanosoma cruzi 28% 100%
V5BV40 Trypanosoma cruzi 58% 100%
V5DCY9 Trypanosoma cruzi 30% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS