SUN domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q2I7_LEIMA

TriTrypDb:

LmjF.34.3570 , LMJLV39_340041900 , LMJSD75_340042200

Length:

941

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 5, no: 0
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q2I7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2I7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	112	116	PF00656	0.594
CLV_C14_Caspase3-7	507	511	PF00656	0.579
CLV_C14_Caspase3-7	514	518	PF00656	0.502
CLV_MEL_PAP_1	475	481	PF00089	0.658
CLV_NRD_NRD_1	138	140	PF00675	0.723
CLV_NRD_NRD_1	149	151	PF00675	0.632
CLV_NRD_NRD_1	331	333	PF00675	0.571
CLV_NRD_NRD_1	343	345	PF00675	0.711
CLV_NRD_NRD_1	368	370	PF00675	0.657
CLV_NRD_NRD_1	373	375	PF00675	0.704
CLV_NRD_NRD_1	392	394	PF00675	0.645
CLV_NRD_NRD_1	406	408	PF00675	0.478
CLV_NRD_NRD_1	441	443	PF00675	0.605
CLV_NRD_NRD_1	658	660	PF00675	0.650
CLV_NRD_NRD_1	849	851	PF00675	0.750
CLV_NRD_NRD_1	923	925	PF00675	0.778
CLV_PCSK_FUR_1	656	660	PF00082	0.657
CLV_PCSK_KEX2_1	138	140	PF00082	0.723
CLV_PCSK_KEX2_1	149	151	PF00082	0.632
CLV_PCSK_KEX2_1	266	268	PF00082	0.760
CLV_PCSK_KEX2_1	306	308	PF00082	0.586
CLV_PCSK_KEX2_1	343	345	PF00082	0.691
CLV_PCSK_KEX2_1	368	370	PF00082	0.657
CLV_PCSK_KEX2_1	373	375	PF00082	0.704
CLV_PCSK_KEX2_1	391	393	PF00082	0.484
CLV_PCSK_KEX2_1	441	443	PF00082	0.610
CLV_PCSK_KEX2_1	658	660	PF00082	0.650
CLV_PCSK_KEX2_1	849	851	PF00082	0.750
CLV_PCSK_KEX2_1	922	924	PF00082	0.864
CLV_PCSK_PC1ET2_1	266	268	PF00082	0.760
CLV_PCSK_PC1ET2_1	306	308	PF00082	0.586
CLV_PCSK_PC1ET2_1	391	393	PF00082	0.484
CLV_PCSK_PC7_1	145	151	PF00082	0.632
CLV_PCSK_PC7_1	369	375	PF00082	0.623
CLV_PCSK_SKI1_1	13	17	PF00082	0.674
CLV_PCSK_SKI1_1	408	412	PF00082	0.479
CLV_PCSK_SKI1_1	547	551	PF00082	0.505
DEG_APCC_DBOX_1	12	20	PF00400	0.558
DEG_COP1_1	726	738	PF00400	0.606
DEG_SPOP_SBC_1	626	630	PF00917	0.771
DOC_CKS1_1	662	667	PF01111	0.627
DOC_CKS1_1	872	877	PF01111	0.750
DOC_CKS1_1	884	889	PF01111	0.610
DOC_CYCLIN_yCln2_LP_2	603	609	PF00134	0.565
DOC_CYCLIN_yCln2_LP_2	61	67	PF00134	0.814
DOC_MAPK_gen_1	691	698	PF00069	0.643
DOC_MAPK_gen_1	79	87	PF00069	0.750
DOC_MAPK_MEF2A_6	17	25	PF00069	0.519
DOC_MAPK_MEF2A_6	81	89	PF00069	0.826
DOC_PP1_RVXF_1	416	422	PF00149	0.519
DOC_PP2B_LxvP_1	104	107	PF13499	0.563
DOC_PP2B_LxvP_1	227	230	PF13499	0.699
DOC_PP2B_LxvP_1	603	606	PF13499	0.585
DOC_PP2B_LxvP_1	61	64	PF13499	0.813
DOC_PP4_FxxP_1	884	887	PF00568	0.634
DOC_PP4_FxxP_1	899	902	PF00568	0.684
DOC_PP4_MxPP_1	770	773	PF00568	0.600
DOC_USP7_MATH_1	176	180	PF00917	0.530
DOC_USP7_MATH_1	202	206	PF00917	0.722
DOC_USP7_MATH_1	209	213	PF00917	0.691
DOC_USP7_MATH_1	221	225	PF00917	0.543
DOC_USP7_MATH_1	230	234	PF00917	0.704
DOC_USP7_MATH_1	292	296	PF00917	0.837
DOC_USP7_MATH_1	300	304	PF00917	0.721
DOC_USP7_MATH_1	385	389	PF00917	0.501
DOC_USP7_MATH_1	515	519	PF00917	0.652
DOC_USP7_MATH_1	567	571	PF00917	0.522
DOC_USP7_MATH_1	597	601	PF00917	0.658
DOC_USP7_MATH_1	633	637	PF00917	0.729
DOC_USP7_MATH_1	650	654	PF00917	0.736
DOC_USP7_MATH_1	748	752	PF00917	0.655
DOC_USP7_MATH_1	763	767	PF00917	0.551
DOC_USP7_MATH_1	805	809	PF00917	0.773
DOC_USP7_MATH_2	612	618	PF00917	0.709
DOC_WW_Pin1_4	29	34	PF00397	0.759
DOC_WW_Pin1_4	595	600	PF00397	0.636
DOC_WW_Pin1_4	627	632	PF00397	0.693
DOC_WW_Pin1_4	643	648	PF00397	0.668
DOC_WW_Pin1_4	661	666	PF00397	0.543
DOC_WW_Pin1_4	744	749	PF00397	0.687
DOC_WW_Pin1_4	784	789	PF00397	0.637
DOC_WW_Pin1_4	801	806	PF00397	0.850
DOC_WW_Pin1_4	822	827	PF00397	0.756
DOC_WW_Pin1_4	836	841	PF00397	0.641
DOC_WW_Pin1_4	853	858	PF00397	0.700
DOC_WW_Pin1_4	868	873	PF00397	0.592
DOC_WW_Pin1_4	883	888	PF00397	0.595
DOC_WW_Pin1_4	900	905	PF00397	0.823
DOC_WW_Pin1_4	913	918	PF00397	0.662
LIG_14-3-3_CanoR_1	420	429	PF00244	0.559
LIG_14-3-3_CanoR_1	470	476	PF00244	0.480
LIG_14-3-3_CanoR_1	624	633	PF00244	0.606
LIG_14-3-3_CanoR_1	762	768	PF00244	0.612
LIG_14-3-3_CterR_2	939	941	PF00244	0.721
LIG_BIR_III_2	833	837	PF00653	0.789
LIG_BRCT_BRCA1_1	206	210	PF00533	0.777
LIG_EH_1	933	937	PF12763	0.813
LIG_FHA_1	535	541	PF00498	0.431
LIG_FHA_1	596	602	PF00498	0.724
LIG_FHA_1	699	705	PF00498	0.657
LIG_FHA_1	822	828	PF00498	0.640
LIG_FHA_1	853	859	PF00498	0.751
LIG_FHA_2	135	141	PF00498	0.632
LIG_FHA_2	294	300	PF00498	0.613
LIG_FHA_2	35	41	PF00498	0.825
LIG_FHA_2	361	367	PF00498	0.515
LIG_FHA_2	428	434	PF00498	0.572
LIG_FHA_2	454	460	PF00498	0.429
LIG_FHA_2	534	540	PF00498	0.556
LIG_FHA_2	550	556	PF00498	0.631
LIG_FHA_2	577	583	PF00498	0.622
LIG_FHA_2	728	734	PF00498	0.805
LIG_GBD_Chelix_1	446	454	PF00786	0.670
LIG_NRBOX	20	26	PF00104	0.682
LIG_Pex14_2	936	940	PF04695	0.802
LIG_PTAP_UEV_1	634	639	PF05743	0.765
LIG_RPA_C_Fungi	388	400	PF08784	0.489
LIG_SH2_STAT5	250	253	PF00017	0.674
LIG_SH3_2	872	877	PF14604	0.750
LIG_SH3_3	583	589	PF00018	0.578
LIG_SH3_3	613	619	PF00018	0.609
LIG_SH3_3	632	638	PF00018	0.558
LIG_SH3_3	641	647	PF00018	0.581
LIG_SH3_3	70	76	PF00018	0.794
LIG_SH3_3	839	845	PF00018	0.692
LIG_SH3_3	86	92	PF00018	0.560
LIG_SH3_3	861	867	PF00018	0.745
LIG_SH3_3	869	875	PF00018	0.649
LIG_SH3_3	889	895	PF00018	0.540
LIG_SH3_3	899	905	PF00018	0.769
LIG_SUMO_SIM_anti_2	455	462	PF11976	0.421
LIG_SUMO_SIM_anti_2	539	544	PF11976	0.564
LIG_SUMO_SIM_anti_2	600	605	PF11976	0.585
LIG_SUMO_SIM_anti_2	701	706	PF11976	0.657
LIG_SUMO_SIM_par_1	614	621	PF11976	0.716
LIG_SUMO_SIM_par_1	63	69	PF11976	0.557
LIG_SUMO_SIM_par_1	82	88	PF11976	0.771
LIG_TRAF2_1	121	124	PF00917	0.538
LIG_TRAF2_1	183	186	PF00917	0.485
LIG_TRAF2_1	196	199	PF00917	0.632
LIG_TRAF2_1	252	255	PF00917	0.662
LIG_TRAF2_1	363	366	PF00917	0.665
LIG_TRAF2_1	430	433	PF00917	0.576
LIG_TRAF2_1	611	614	PF00917	0.771
LIG_TRAF2_1	815	818	PF00917	0.715
LIG_WW_2	892	895	PF00397	0.587
LIG_WW_3	771	775	PF00397	0.609
MOD_CDC14_SPxK_1	747	750	PF00782	0.729
MOD_CDK_SPK_2	643	648	PF00069	0.779
MOD_CDK_SPxK_1	744	750	PF00069	0.731
MOD_CDK_SPxK_1	871	877	PF00069	0.752
MOD_CDK_SPxxK_3	661	668	PF00069	0.708
MOD_CDK_SPxxK_3	822	829	PF00069	0.751
MOD_CDK_SPxxK_3	883	890	PF00069	0.754
MOD_CK1_1	188	194	PF00069	0.691
MOD_CK1_1	239	245	PF00069	0.743
MOD_CK1_1	28	34	PF00069	0.762
MOD_CK1_1	453	459	PF00069	0.421
MOD_CK1_1	486	492	PF00069	0.592
MOD_CK1_1	617	623	PF00069	0.797
MOD_CK1_1	675	681	PF00069	0.757
MOD_CK1_1	741	747	PF00069	0.778
MOD_CK1_1	766	772	PF00069	0.845
MOD_CK1_1	806	812	PF00069	0.865
MOD_CK1_1	871	877	PF00069	0.818
MOD_CK2_1	160	166	PF00069	0.611
MOD_CK2_1	193	199	PF00069	0.844
MOD_CK2_1	249	255	PF00069	0.604
MOD_CK2_1	292	298	PF00069	0.778
MOD_CK2_1	360	366	PF00069	0.513
MOD_CK2_1	427	433	PF00069	0.571
MOD_CK2_1	453	459	PF00069	0.424
MOD_CK2_1	508	514	PF00069	0.582
MOD_CK2_1	533	539	PF00069	0.564
MOD_CK2_1	576	582	PF00069	0.691
MOD_CK2_1	63	69	PF00069	0.543
MOD_CK2_1	670	676	PF00069	0.675
MOD_CK2_1	786	792	PF00069	0.848
MOD_CK2_1	873	879	PF00069	0.757
MOD_DYRK1A_RPxSP_1	643	647	PF00069	0.702
MOD_GlcNHglycan	190	193	PF01048	0.758
MOD_GlcNHglycan	204	207	PF01048	0.669
MOD_GlcNHglycan	211	214	PF01048	0.681
MOD_GlcNHglycan	241	244	PF01048	0.604
MOD_GlcNHglycan	387	390	PF01048	0.656
MOD_GlcNHglycan	437	440	PF01048	0.648
MOD_GlcNHglycan	471	474	PF01048	0.524
MOD_GlcNHglycan	479	482	PF01048	0.614
MOD_GlcNHglycan	635	638	PF01048	0.807
MOD_GlcNHglycan	718	721	PF01048	0.756
MOD_GlcNHglycan	754	757	PF01048	0.804
MOD_GlcNHglycan	792	795	PF01048	0.748
MOD_GlcNHglycan	805	808	PF01048	0.703
MOD_GlcNHglycan	907	910	PF01048	0.730
MOD_GSK3_1	239	246	PF00069	0.790
MOD_GSK3_1	25	32	PF00069	0.698
MOD_GSK3_1	423	430	PF00069	0.498
MOD_GSK3_1	482	489	PF00069	0.541
MOD_GSK3_1	534	541	PF00069	0.441
MOD_GSK3_1	595	602	PF00069	0.641
MOD_GSK3_1	627	634	PF00069	0.727
MOD_GSK3_1	639	646	PF00069	0.545
MOD_GSK3_1	670	677	PF00069	0.610
MOD_GSK3_1	744	751	PF00069	0.636
MOD_GSK3_1	782	789	PF00069	0.624
MOD_GSK3_1	797	804	PF00069	0.657
MOD_GSK3_1	853	860	PF00069	0.758
MOD_GSK3_1	867	874	PF00069	0.695
MOD_NEK2_1	238	243	PF00069	0.605
MOD_NEK2_1	25	30	PF00069	0.678
MOD_NEK2_1	482	487	PF00069	0.675
MOD_PIKK_1	427	433	PF00454	0.571
MOD_PIKK_1	486	492	PF00454	0.606
MOD_PIKK_1	51	57	PF00454	0.579
MOD_PIKK_1	797	803	PF00454	0.831
MOD_PKA_2	125	131	PF00069	0.523
MOD_PKA_2	193	199	PF00069	0.770
MOD_PKA_2	469	475	PF00069	0.627
MOD_PKA_2	477	483	PF00069	0.542
MOD_PKA_2	626	632	PF00069	0.612
MOD_PKB_1	418	426	PF00069	0.559
MOD_Plk_1	122	128	PF00069	0.685
MOD_Plk_1	185	191	PF00069	0.613
MOD_Plk_1	442	448	PF00069	0.453
MOD_Plk_1	538	544	PF00069	0.414
MOD_Plk_1	670	676	PF00069	0.678
MOD_Plk_1	741	747	PF00069	0.698
MOD_Plk_1	85	91	PF00069	0.817
MOD_Plk_2-3	160	166	PF00069	0.475
MOD_Plk_2-3	728	734	PF00069	0.727
MOD_Plk_4	246	252	PF00069	0.632
MOD_Plk_4	31	37	PF00069	0.801
MOD_Plk_4	599	605	PF00069	0.671
MOD_Plk_4	698	704	PF00069	0.652
MOD_Plk_4	766	772	PF00069	0.612
MOD_ProDKin_1	29	35	PF00069	0.766
MOD_ProDKin_1	595	601	PF00069	0.642
MOD_ProDKin_1	627	633	PF00069	0.691
MOD_ProDKin_1	643	649	PF00069	0.668
MOD_ProDKin_1	661	667	PF00069	0.546
MOD_ProDKin_1	744	750	PF00069	0.690
MOD_ProDKin_1	784	790	PF00069	0.636
MOD_ProDKin_1	801	807	PF00069	0.851
MOD_ProDKin_1	822	828	PF00069	0.758
MOD_ProDKin_1	836	842	PF00069	0.638
MOD_ProDKin_1	853	859	PF00069	0.702
MOD_ProDKin_1	868	874	PF00069	0.592
MOD_ProDKin_1	883	889	PF00069	0.595
MOD_ProDKin_1	900	906	PF00069	0.820
MOD_ProDKin_1	913	919	PF00069	0.662
MOD_SUMO_rev_2	248	258	PF00179	0.689
MOD_SUMO_rev_2	263	268	PF00179	0.584
MOD_SUMO_rev_2	293	303	PF00179	0.775
MOD_SUMO_rev_2	449	458	PF00179	0.553
MOD_SUMO_rev_2	577	586	PF00179	0.475
TRG_DiLeu_BaEn_4	817	823	PF01217	0.704
TRG_ER_diArg_1	149	151	PF00400	0.632
TRG_ER_diArg_1	367	369	PF00400	0.511
TRG_ER_diArg_1	418	421	PF00400	0.633
TRG_ER_diArg_1	440	442	PF00400	0.552
TRG_ER_diArg_1	475	478	PF00400	0.589
TRG_ER_diArg_1	657	659	PF00400	0.664
TRG_ER_diArg_1	848	850	PF00400	0.761
TRG_ER_diArg_1	922	924	PF00400	0.729
TRG_NES_CRM1_1	225	237	PF08389	0.610
TRG_NES_CRM1_1	449	464	PF08389	0.433
TRG_NLS_Bipartite_1	373	395	PF00514	0.483
TRG_NLS_MonoCore_2	390	395	PF00514	0.464
TRG_Pf-PMV_PEXEL_1	120	124	PF00026	0.605
TRG_Pf-PMV_PEXEL_1	149	153	PF00026	0.597
TRG_Pf-PMV_PEXEL_1	659	663	PF00026	0.652

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X8C0	Leishmania donovani	82%	100%
A4HB75	Leishmania braziliensis	49%	90%
A4IAC3	Leishmania infantum	82%	100%
E9B5E6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	93%