Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania major

UniProt:

Q4Q2G9_LEIMA

TriTrypDb:

LmjF.34.3745 , LMJLV39_340043800 , LMJSD75_340044200

Length:

499

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q2G9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2G9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	224	228	PF00656	0.628
CLV_C14_Caspase3-7	463	467	PF00656	0.549
CLV_C14_Caspase3-7	48	52	PF00656	0.498
CLV_MEL_PAP_1	151	157	PF00089	0.578
CLV_NRD_NRD_1	215	217	PF00675	0.772
CLV_NRD_NRD_1	246	248	PF00675	0.628
CLV_NRD_NRD_1	346	348	PF00675	0.603
CLV_PCSK_KEX2_1	215	217	PF00082	0.772
CLV_PCSK_KEX2_1	246	248	PF00082	0.619
CLV_PCSK_KEX2_1	84	86	PF00082	0.568
CLV_PCSK_PC1ET2_1	84	86	PF00082	0.650
CLV_PCSK_SKI1_1	165	169	PF00082	0.511
CLV_PCSK_SKI1_1	265	269	PF00082	0.661
CLV_PCSK_SKI1_1	422	426	PF00082	0.632
CLV_PCSK_SKI1_1	67	71	PF00082	0.534
CLV_PCSK_SKI1_1	99	103	PF00082	0.654
DEG_APCC_DBOX_1	215	223	PF00400	0.670
DOC_CKS1_1	431	436	PF01111	0.546
DOC_CYCLIN_RxL_1	449	460	PF00134	0.545
DOC_PP2B_LxvP_1	182	185	PF13499	0.563
DOC_PP2B_LxvP_1	267	270	PF13499	0.574
DOC_USP7_MATH_1	138	142	PF00917	0.598
DOC_USP7_MATH_1	252	256	PF00917	0.624
DOC_USP7_MATH_1	351	355	PF00917	0.626
DOC_USP7_MATH_1	360	364	PF00917	0.609
DOC_USP7_MATH_1	448	452	PF00917	0.536
DOC_USP7_MATH_1	475	479	PF00917	0.632
DOC_WW_Pin1_4	108	113	PF00397	0.802
DOC_WW_Pin1_4	271	276	PF00397	0.752
DOC_WW_Pin1_4	314	319	PF00397	0.708
DOC_WW_Pin1_4	331	336	PF00397	0.634
DOC_WW_Pin1_4	338	343	PF00397	0.579
DOC_WW_Pin1_4	379	384	PF00397	0.741
DOC_WW_Pin1_4	430	435	PF00397	0.549
DOC_WW_Pin1_4	440	445	PF00397	0.620
DOC_WW_Pin1_4	491	496	PF00397	0.556
DOC_WW_Pin1_4	73	78	PF00397	0.556
LIG_14-3-3_CanoR_1	154	164	PF00244	0.553
LIG_14-3-3_CanoR_1	308	318	PF00244	0.629
LIG_BIR_II_1	1	5	PF00653	0.630
LIG_BIR_III_1	1	5	PF00653	0.630
LIG_BIR_III_3	1	5	PF00653	0.630
LIG_BIR_III_4	49	53	PF00653	0.581
LIG_BRCT_BRCA1_1	157	161	PF00533	0.558
LIG_BRCT_BRCA1_1	353	357	PF00533	0.679
LIG_BRCT_BRCA1_1	365	369	PF00533	0.581
LIG_BRCT_BRCA1_1	371	375	PF00533	0.562
LIG_BRCT_BRCA1_1	409	413	PF00533	0.645
LIG_BRCT_BRCA1_1	75	79	PF00533	0.598
LIG_Clathr_ClatBox_1	78	82	PF01394	0.628
LIG_FHA_1	284	290	PF00498	0.650
LIG_FHA_1	339	345	PF00498	0.602
LIG_FHA_1	382	388	PF00498	0.588
LIG_FHA_1	423	429	PF00498	0.586
LIG_FHA_1	437	443	PF00498	0.513
LIG_FHA_1	451	457	PF00498	0.528
LIG_FHA_1	66	72	PF00498	0.471
LIG_FHA_1	96	102	PF00498	0.564
LIG_FHA_2	158	164	PF00498	0.551
LIG_FHA_2	222	228	PF00498	0.674
LIG_FHA_2	46	52	PF00498	0.476
LIG_LIR_Gen_1	372	383	PF02991	0.558
LIG_LIR_Gen_1	38	46	PF02991	0.504
LIG_LIR_Nem_3	158	164	PF02991	0.563
LIG_LIR_Nem_3	372	378	PF02991	0.558
LIG_LIR_Nem_3	38	43	PF02991	0.513
LIG_MYND_1	207	211	PF01753	0.593
LIG_MYND_1	217	221	PF01753	0.644
LIG_Rb_LxCxE_1	310	326	PF01857	0.563
LIG_SH2_CRK	164	168	PF00017	0.558
LIG_SH2_CRK	40	44	PF00017	0.441
LIG_SH2_CRK	75	79	PF00017	0.521
LIG_SH2_STAT5	152	155	PF00017	0.557
LIG_SH2_STAT5	40	43	PF00017	0.443
LIG_SH3_2	211	216	PF14604	0.656
LIG_SH3_3	106	112	PF00018	0.590
LIG_SH3_3	208	214	PF00018	0.664
LIG_SH3_3	267	273	PF00018	0.641
LIG_SH3_3	286	292	PF00018	0.553
LIG_SH3_3	315	321	PF00018	0.622
LIG_SH3_3	428	434	PF00018	0.550
LIG_SH3_CIN85_PxpxPR_1	288	293	PF14604	0.551
LIG_SUMO_SIM_par_1	195	202	PF11976	0.560
LIG_TYR_ITSM	36	43	PF00017	0.468
MOD_CDK_SPxxK_3	108	115	PF00069	0.613
MOD_CDK_SPxxK_3	442	449	PF00069	0.611
MOD_CK1_1	113	119	PF00069	0.608
MOD_CK1_1	127	133	PF00069	0.617
MOD_CK1_1	141	147	PF00069	0.519
MOD_CK1_1	186	192	PF00069	0.660
MOD_CK1_1	230	236	PF00069	0.681
MOD_CK1_1	253	259	PF00069	0.632
MOD_CK1_1	274	280	PF00069	0.700
MOD_CK1_1	317	323	PF00069	0.707
MOD_CK1_1	35	41	PF00069	0.662
MOD_CK1_1	363	369	PF00069	0.561
MOD_CK1_1	379	385	PF00069	0.648
MOD_CK1_1	392	398	PF00069	0.616
MOD_CK1_1	407	413	PF00069	0.501
MOD_CK1_1	440	446	PF00069	0.727
MOD_CK2_1	157	163	PF00069	0.557
MOD_CK2_1	196	202	PF00069	0.560
MOD_CK2_1	309	315	PF00069	0.600
MOD_GlcNHglycan	115	118	PF01048	0.535
MOD_GlcNHglycan	136	139	PF01048	0.707
MOD_GlcNHglycan	143	146	PF01048	0.613
MOD_GlcNHglycan	21	24	PF01048	0.664
MOD_GlcNHglycan	252	255	PF01048	0.712
MOD_GlcNHglycan	357	360	PF01048	0.643
MOD_GlcNHglycan	366	369	PF01048	0.538
MOD_GlcNHglycan	384	387	PF01048	0.777
MOD_GlcNHglycan	391	394	PF01048	0.756
MOD_GlcNHglycan	406	409	PF01048	0.532
MOD_GlcNHglycan	428	431	PF01048	0.558
MOD_GlcNHglycan	477	480	PF01048	0.553
MOD_GlcNHglycan	496	499	PF01048	0.477
MOD_GSK3_1	124	131	PF00069	0.805
MOD_GSK3_1	134	141	PF00069	0.696
MOD_GSK3_1	271	278	PF00069	0.724
MOD_GSK3_1	351	358	PF00069	0.599
MOD_GSK3_1	360	367	PF00069	0.578
MOD_GSK3_1	377	384	PF00069	0.580
MOD_GSK3_1	385	392	PF00069	0.735
MOD_GSK3_1	400	407	PF00069	0.594
MOD_GSK3_1	418	425	PF00069	0.479
MOD_GSK3_1	426	433	PF00069	0.558
MOD_GSK3_1	436	443	PF00069	0.592
MOD_GSK3_1	448	455	PF00069	0.530
MOD_GSK3_1	457	464	PF00069	0.555
MOD_GSK3_1	61	68	PF00069	0.564
MOD_GSK3_1	95	102	PF00069	0.628
MOD_LATS_1	420	426	PF00433	0.577
MOD_N-GLC_1	156	161	PF02516	0.582
MOD_N-GLC_1	32	37	PF02516	0.608
MOD_NEK2_1	307	312	PF00069	0.557
MOD_NEK2_1	369	374	PF00069	0.566
MOD_NEK2_1	376	381	PF00069	0.574
MOD_NEK2_1	400	405	PF00069	0.658
MOD_NEK2_1	435	440	PF00069	0.552
MOD_NEK2_1	452	457	PF00069	0.495
MOD_NEK2_2	196	201	PF00069	0.562
MOD_PIKK_1	253	259	PF00454	0.720
MOD_PIKK_1	377	383	PF00454	0.587
MOD_PIKK_1	433	439	PF00454	0.540
MOD_PIKK_1	469	475	PF00454	0.608
MOD_PKA_1	215	221	PF00069	0.670
MOD_PKA_2	170	176	PF00069	0.574
MOD_PKA_2	215	221	PF00069	0.657
MOD_PKA_2	307	313	PF00069	0.558
MOD_PKA_2	404	410	PF00069	0.570
MOD_PKA_2	418	424	PF00069	0.495
MOD_PKA_2	61	67	PF00069	0.564
MOD_Plk_1	156	162	PF00069	0.583
MOD_Plk_1	186	192	PF00069	0.647
MOD_Plk_1	32	38	PF00069	0.549
MOD_Plk_1	422	428	PF00069	0.637
MOD_Plk_2-3	45	51	PF00069	0.467
MOD_Plk_4	32	38	PF00069	0.626
MOD_Plk_4	370	376	PF00069	0.562
MOD_Plk_4	67	73	PF00069	0.610
MOD_ProDKin_1	108	114	PF00069	0.805
MOD_ProDKin_1	271	277	PF00069	0.750
MOD_ProDKin_1	314	320	PF00069	0.707
MOD_ProDKin_1	331	337	PF00069	0.633
MOD_ProDKin_1	338	344	PF00069	0.581
MOD_ProDKin_1	379	385	PF00069	0.744
MOD_ProDKin_1	430	436	PF00069	0.551
MOD_ProDKin_1	440	446	PF00069	0.619
MOD_ProDKin_1	491	497	PF00069	0.556
MOD_ProDKin_1	73	79	PF00069	0.559
MOD_SUMO_rev_2	264	270	PF00179	0.720
MOD_SUMO_rev_2	76	86	PF00179	0.551
TRG_DiLeu_BaEn_1	423	428	PF01217	0.586
TRG_ENDOCYTIC_2	152	155	PF00928	0.557
TRG_ENDOCYTIC_2	164	167	PF00928	0.551
TRG_ENDOCYTIC_2	40	43	PF00928	0.448
TRG_ENDOCYTIC_2	75	78	PF00928	0.515
TRG_ER_diArg_1	214	216	PF00400	0.773
TRG_ER_diArg_1	245	247	PF00400	0.577
TRG_ER_diArg_1	85	88	PF00400	0.643
TRG_NLS_MonoExtC_3	83	89	PF00514	0.574
TRG_Pf-PMV_PEXEL_1	327	331	PF00026	0.579

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PF19	Leptomonas seymouri	33%	100%
A0A3S5H7X8	Leishmania donovani	81%	100%
A4HB94	Leishmania braziliensis	58%	100%
A4IAE2	Leishmania infantum	81%	100%
E9B5G6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%