Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q2G8_LEIMA

TriTrypDb:

LmjF.34.3750 , LMJLV39_340043900 , LMJSD75_340044300

Length:

517

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q2G8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2G8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	300	304	PF00656	0.600
CLV_C14_Caspase3-7	424	428	PF00656	0.718
CLV_NRD_NRD_1	30	32	PF00675	0.783
CLV_NRD_NRD_1	334	336	PF00675	0.670
CLV_NRD_NRD_1	363	365	PF00675	0.728
CLV_NRD_NRD_1	402	404	PF00675	0.712
CLV_NRD_NRD_1	406	408	PF00675	0.682
CLV_PCSK_KEX2_1	149	151	PF00082	0.619
CLV_PCSK_KEX2_1	162	164	PF00082	0.377
CLV_PCSK_KEX2_1	30	32	PF00082	0.688

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5K2	Leptomonas seymouri	38%	89%
A0A3Q8INS4	Leishmania donovani	83%	100%
A4HB95	Leishmania braziliensis	60%	90%
A4IAE3	Leishmania infantum	84%	100%
E9B5G7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	96%

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