HECT domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

HECT-domain (ubiquitin-transferase), putative

Species:

Leishmania major

UniProt:

Q4Q2E5_LEIMA

TriTrypDb:

LmjF.34.3960 , LMJLV39_340046200 , LMJSD75_340046600

Length:

1369

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q2E5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0000209	protein polyubiquitination	8	2
GO:0006508	proteolysis	4	10
GO:0006511	ubiquitin-dependent protein catabolic process	7	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0008152	metabolic process	1	10
GO:0009056	catabolic process	2	10
GO:0009057	macromolecule catabolic process	4	10
GO:0009987	cellular process	1	10
GO:0010498	proteasomal protein catabolic process	5	2
GO:0016567	protein ubiquitination	7	2
GO:0019538	protein metabolic process	3	10
GO:0019941	modification-dependent protein catabolic process	6	10
GO:0030163	protein catabolic process	4	2
GO:0032446	protein modification by small protein conjugation	6	2
GO:0036211	protein modification process	4	2
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	6	2
GO:0043170	macromolecule metabolic process	3	10
GO:0043412	macromolecule modification	4	2
GO:0043632	modification-dependent macromolecule catabolic process	5	10
GO:0044237	cellular metabolic process	2	10
GO:0044238	primary metabolic process	2	10
GO:0044248	cellular catabolic process	3	10
GO:0044260	obsolete cellular macromolecule metabolic process	3	10
GO:0044265	obsolete cellular macromolecule catabolic process	4	10
GO:0051603	proteolysis involved in protein catabolic process	5	10
GO:0070647	protein modification by small protein conjugation or removal	5	2
GO:0071704	organic substance metabolic process	2	10
GO:1901564	organonitrogen compound metabolic process	3	10
GO:1901565	organonitrogen compound catabolic process	4	2
GO:1901575	organic substance catabolic process	3	10

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	10
GO:0004842	ubiquitin-protein transferase activity	4	10
GO:0016740	transferase activity	2	10
GO:0019787	ubiquitin-like protein transferase activity	3	10
GO:0061630	ubiquitin protein ligase activity	5	10
GO:0061659	ubiquitin-like protein ligase activity	4	10
GO:0140096	catalytic activity, acting on a protein	2	10
GO:0005488	binding	1	3
GO:0008270	zinc ion binding	6	2
GO:0043167	ion binding	2	3
GO:0043169	cation binding	3	3
GO:0046872	metal ion binding	4	3
GO:0046914	transition metal ion binding	5	2
GO:0016874	ligase activity	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	104	108	PF00656	0.537
CLV_C14_Caspase3-7	593	597	PF00656	0.510
CLV_NRD_NRD_1	1363	1365	PF00675	0.367
CLV_NRD_NRD_1	242	244	PF00675	0.649
CLV_NRD_NRD_1	245	247	PF00675	0.632
CLV_NRD_NRD_1	432	434	PF00675	0.497
CLV_NRD_NRD_1	515	517	PF00675	0.453
CLV_NRD_NRD_1	605	607	PF00675	0.564
CLV_NRD_NRD_1	622	624	PF00675	0.615
CLV_NRD_NRD_1	649	651	PF00675	0.572
CLV_NRD_NRD_1	735	737	PF00675	0.567
CLV_NRD_NRD_1	920	922	PF00675	0.493
CLV_NRD_NRD_1	973	975	PF00675	0.422
CLV_PCSK_KEX2_1	116	118	PF00082	0.522
CLV_PCSK_KEX2_1	1363	1365	PF00082	0.441
CLV_PCSK_KEX2_1	242	244	PF00082	0.658
CLV_PCSK_KEX2_1	247	249	PF00082	0.611
CLV_PCSK_KEX2_1	432	434	PF00082	0.532
CLV_PCSK_KEX2_1	457	459	PF00082	0.484
CLV_PCSK_KEX2_1	605	607	PF00082	0.634
CLV_PCSK_KEX2_1	622	624	PF00082	0.615
CLV_PCSK_KEX2_1	649	651	PF00082	0.572
CLV_PCSK_KEX2_1	723	725	PF00082	0.539
CLV_PCSK_KEX2_1	735	737	PF00082	0.528
CLV_PCSK_KEX2_1	920	922	PF00082	0.493
CLV_PCSK_KEX2_1	973	975	PF00082	0.415
CLV_PCSK_PC1ET2_1	116	118	PF00082	0.522
CLV_PCSK_PC1ET2_1	242	244	PF00082	0.654
CLV_PCSK_PC1ET2_1	247	249	PF00082	0.592
CLV_PCSK_PC1ET2_1	457	459	PF00082	0.484
CLV_PCSK_PC1ET2_1	723	725	PF00082	0.547
CLV_PCSK_PC7_1	243	249	PF00082	0.709
CLV_PCSK_SKI1_1	1085	1089	PF00082	0.420
CLV_PCSK_SKI1_1	1090	1094	PF00082	0.379
CLV_PCSK_SKI1_1	1236	1240	PF00082	0.469
CLV_PCSK_SKI1_1	1313	1317	PF00082	0.339
CLV_PCSK_SKI1_1	1354	1358	PF00082	0.339
CLV_PCSK_SKI1_1	190	194	PF00082	0.511
CLV_PCSK_SKI1_1	214	218	PF00082	0.480
CLV_PCSK_SKI1_1	333	337	PF00082	0.522
CLV_PCSK_SKI1_1	468	472	PF00082	0.508
CLV_PCSK_SKI1_1	479	483	PF00082	0.312
CLV_PCSK_SKI1_1	557	561	PF00082	0.493
CLV_PCSK_SKI1_1	649	653	PF00082	0.603
CLV_PCSK_SKI1_1	67	71	PF00082	0.390
CLV_PCSK_SKI1_1	843	847	PF00082	0.506
CLV_PCSK_SKI1_1	90	94	PF00082	0.382
CLV_PCSK_SKI1_1	920	924	PF00082	0.506
CLV_PCSK_SKI1_1	946	950	PF00082	0.483
CLV_PCSK_SKI1_1	974	978	PF00082	0.471
DEG_APCC_DBOX_1	339	347	PF00400	0.357
DEG_APCC_DBOX_1	460	468	PF00400	0.433
DEG_APCC_DBOX_1	636	644	PF00400	0.554
DEG_APCC_DBOX_1	734	742	PF00400	0.518
DEG_SCF_FBW7_1	610	615	PF00400	0.579
DEG_SCF_TRCP1_1	109	115	PF00400	0.485
DEG_SPOP_SBC_1	356	360	PF00917	0.513
DEG_SPOP_SBC_1	831	835	PF00917	0.499
DOC_CDC14_PxL_1	1120	1128	PF14671	0.444
DOC_CKS1_1	415	420	PF01111	0.572
DOC_CKS1_1	629	634	PF01111	0.543
DOC_CYCLIN_RxL_1	1082	1091	PF00134	0.485
DOC_CYCLIN_RxL_1	1348	1361	PF00134	0.441
DOC_CYCLIN_RxL_1	64	71	PF00134	0.394
DOC_CYCLIN_RxL_1	917	927	PF00134	0.509
DOC_CYCLIN_yCln2_LP_2	1311	1317	PF00134	0.252
DOC_CYCLIN_yCln2_LP_2	38	44	PF00134	0.601
DOC_MAPK_gen_1	1008	1017	PF00069	0.510
DOC_MAPK_gen_1	1352	1359	PF00069	0.433
DOC_MAPK_gen_1	211	221	PF00069	0.455
DOC_MAPK_gen_1	337	345	PF00069	0.511
DOC_MAPK_gen_1	432	442	PF00069	0.541
DOC_MAPK_gen_1	456	464	PF00069	0.508
DOC_MAPK_gen_1	723	730	PF00069	0.520
DOC_MAPK_HePTP_8	720	732	PF00069	0.557
DOC_MAPK_JIP1_4	1011	1017	PF00069	0.566
DOC_MAPK_MEF2A_6	1352	1359	PF00069	0.433
DOC_MAPK_MEF2A_6	153	162	PF00069	0.508
DOC_MAPK_MEF2A_6	214	223	PF00069	0.456
DOC_MAPK_MEF2A_6	723	732	PF00069	0.564
DOC_MAPK_NFAT4_5	1352	1360	PF00069	0.433
DOC_MAPK_RevD_3	720	736	PF00069	0.372
DOC_MAPK_RevD_3	958	974	PF00069	0.468
DOC_PP1_RVXF_1	1029	1035	PF00149	0.396
DOC_PP1_RVXF_1	477	483	PF00149	0.377
DOC_PP1_RVXF_1	841	848	PF00149	0.593
DOC_PP2B_LxvP_1	1121	1124	PF13499	0.444
DOC_PP2B_LxvP_1	1126	1129	PF13499	0.444
DOC_PP2B_LxvP_1	1340	1343	PF13499	0.476
DOC_PP4_FxxP_1	470	473	PF00568	0.422
DOC_PP4_FxxP_1	761	764	PF00568	0.561
DOC_SPAK_OSR1_1	1204	1208	PF12202	0.408
DOC_USP7_MATH_1	131	135	PF00917	0.471
DOC_USP7_MATH_1	16	20	PF00917	0.496
DOC_USP7_MATH_1	199	203	PF00917	0.522
DOC_USP7_MATH_1	260	264	PF00917	0.628
DOC_USP7_MATH_1	297	301	PF00917	0.474
DOC_USP7_MATH_1	317	321	PF00917	0.439
DOC_USP7_MATH_1	356	360	PF00917	0.534
DOC_USP7_MATH_1	497	501	PF00917	0.461
DOC_USP7_MATH_1	589	593	PF00917	0.474
DOC_USP7_MATH_1	831	835	PF00917	0.604
DOC_USP7_MATH_1	896	900	PF00917	0.320
DOC_USP7_MATH_1	925	929	PF00917	0.463
DOC_USP7_UBL2_3	80	84	PF12436	0.429
DOC_WW_Pin1_4	1024	1029	PF00397	0.441
DOC_WW_Pin1_4	1136	1141	PF00397	0.464
DOC_WW_Pin1_4	1297	1302	PF00397	0.339
DOC_WW_Pin1_4	227	232	PF00397	0.614
DOC_WW_Pin1_4	288	293	PF00397	0.474
DOC_WW_Pin1_4	414	419	PF00397	0.559
DOC_WW_Pin1_4	570	575	PF00397	0.511
DOC_WW_Pin1_4	608	613	PF00397	0.579
DOC_WW_Pin1_4	628	633	PF00397	0.515
DOC_WW_Pin1_4	855	860	PF00397	0.491
DOC_WW_Pin1_4	880	885	PF00397	0.490
DOC_WW_Pin1_4	995	1000	PF00397	0.648
LIG_14-3-3_CanoR_1	1167	1174	PF00244	0.370
LIG_14-3-3_CanoR_1	1258	1267	PF00244	0.436
LIG_14-3-3_CanoR_1	1313	1318	PF00244	0.339
LIG_14-3-3_CanoR_1	1363	1369	PF00244	0.339
LIG_14-3-3_CanoR_1	196	203	PF00244	0.514
LIG_14-3-3_CanoR_1	214	223	PF00244	0.492
LIG_14-3-3_CanoR_1	248	253	PF00244	0.728
LIG_14-3-3_CanoR_1	261	267	PF00244	0.487
LIG_14-3-3_CanoR_1	296	306	PF00244	0.443
LIG_14-3-3_CanoR_1	337	346	PF00244	0.549
LIG_14-3-3_CanoR_1	461	471	PF00244	0.398
LIG_14-3-3_CanoR_1	605	611	PF00244	0.582
LIG_14-3-3_CanoR_1	637	645	PF00244	0.393
LIG_14-3-3_CanoR_1	735	739	PF00244	0.528
LIG_14-3-3_CanoR_1	757	764	PF00244	0.499
LIG_14-3-3_CanoR_1	851	860	PF00244	0.463
LIG_14-3-3_CanoR_1	865	869	PF00244	0.254
LIG_14-3-3_CanoR_1	946	956	PF00244	0.513
LIG_Actin_WH2_2	160	177	PF00022	0.398
LIG_Actin_WH2_2	592	607	PF00022	0.499
LIG_Actin_WH2_2	636	651	PF00022	0.509
LIG_APCC_ABBAyCdc20_2	843	849	PF00400	0.585
LIG_BIR_II_1	1	5	PF00653	0.439
LIG_BIR_III_4	1244	1248	PF00653	0.291
LIG_BRCT_BRCA1_1	1054	1058	PF00533	0.460
LIG_BRCT_BRCA1_1	299	303	PF00533	0.506
LIG_BRCT_BRCA1_1	757	761	PF00533	0.558
LIG_Clathr_ClatBox_1	1029	1033	PF01394	0.510
LIG_deltaCOP1_diTrp_1	469	474	PF00928	0.453
LIG_EH_1	346	350	PF12763	0.502
LIG_eIF4E_1	540	546	PF01652	0.437
LIG_FAT_LD_1	660	668	PF03623	0.544
LIG_FAT_LD_1	713	721	PF03623	0.532
LIG_FHA_1	1082	1088	PF00498	0.485
LIG_FHA_1	1147	1153	PF00498	0.432
LIG_FHA_1	1333	1339	PF00498	0.339
LIG_FHA_1	1345	1351	PF00498	0.339
LIG_FHA_1	23	29	PF00498	0.417
LIG_FHA_1	289	295	PF00498	0.498
LIG_FHA_1	334	340	PF00498	0.508
LIG_FHA_1	362	368	PF00498	0.683
LIG_FHA_1	486	492	PF00498	0.527
LIG_FHA_1	571	577	PF00498	0.477
LIG_FHA_1	598	604	PF00498	0.564
LIG_FHA_1	629	635	PF00498	0.589
LIG_FHA_1	716	722	PF00498	0.492
LIG_FHA_1	818	824	PF00498	0.540
LIG_FHA_1	840	846	PF00498	0.603
LIG_FHA_1	865	871	PF00498	0.427
LIG_FHA_1	947	953	PF00498	0.518
LIG_FHA_1	963	969	PF00498	0.461
LIG_FHA_2	102	108	PF00498	0.524
LIG_FHA_2	1066	1072	PF00498	0.493
LIG_FHA_2	1187	1193	PF00498	0.494
LIG_FHA_2	1201	1207	PF00498	0.481
LIG_FHA_2	1251	1257	PF00498	0.441
LIG_FHA_2	196	202	PF00498	0.509
LIG_FHA_2	231	237	PF00498	0.596
LIG_FHA_2	464	470	PF00498	0.436
LIG_FHA_2	591	597	PF00498	0.503
LIG_FHA_2	654	660	PF00498	0.476
LIG_FHA_2	666	672	PF00498	0.403
LIG_FHA_2	817	823	PF00498	0.540
LIG_FHA_2	977	983	PF00498	0.461
LIG_GBD_Chelix_1	327	335	PF00786	0.594
LIG_Integrin_isoDGR_2	755	757	PF01839	0.460
LIG_LIR_Apic_2	469	473	PF02991	0.476
LIG_LIR_Apic_2	758	764	PF02991	0.541
LIG_LIR_Gen_1	1049	1058	PF02991	0.398
LIG_LIR_Gen_1	1162	1169	PF02991	0.400
LIG_LIR_Gen_1	1292	1301	PF02991	0.494
LIG_LIR_Gen_1	1335	1345	PF02991	0.339
LIG_LIR_Gen_1	14	23	PF02991	0.406
LIG_LIR_Gen_1	208	216	PF02991	0.389
LIG_LIR_Gen_1	300	310	PF02991	0.452
LIG_LIR_Gen_1	71	81	PF02991	0.261
LIG_LIR_Gen_1	91	100	PF02991	0.331
LIG_LIR_Gen_1	965	975	PF02991	0.406
LIG_LIR_LC3C_4	718	722	PF02991	0.413
LIG_LIR_Nem_3	1020	1025	PF02991	0.371
LIG_LIR_Nem_3	1049	1054	PF02991	0.416
LIG_LIR_Nem_3	1061	1067	PF02991	0.378
LIG_LIR_Nem_3	1091	1095	PF02991	0.378
LIG_LIR_Nem_3	1162	1166	PF02991	0.448
LIG_LIR_Nem_3	1292	1296	PF02991	0.494
LIG_LIR_Nem_3	1335	1340	PF02991	0.339
LIG_LIR_Nem_3	14	20	PF02991	0.411
LIG_LIR_Nem_3	208	212	PF02991	0.403
LIG_LIR_Nem_3	300	306	PF02991	0.461
LIG_LIR_Nem_3	397	403	PF02991	0.449
LIG_LIR_Nem_3	419	425	PF02991	0.495
LIG_LIR_Nem_3	71	76	PF02991	0.364
LIG_LIR_Nem_3	91	96	PF02991	0.323
LIG_LIR_Nem_3	965	970	PF02991	0.404
LIG_MLH1_MIPbox_1	1054	1058	PF16413	0.475
LIG_MYND_1	632	636	PF01753	0.565
LIG_NRBOX	1147	1153	PF00104	0.444
LIG_NRBOX	44	50	PF00104	0.520
LIG_NRBOX	545	551	PF00104	0.471
LIG_NRBOX	712	718	PF00104	0.536
LIG_NRBOX	900	906	PF00104	0.472
LIG_PCNA_TLS_4	67	74	PF02747	0.456
LIG_PCNA_yPIPBox_3	1213	1223	PF02747	0.441
LIG_Pex14_2	1088	1092	PF04695	0.444
LIG_Pex14_2	470	474	PF04695	0.382
LIG_PTB_Apo_2	441	448	PF02174	0.454
LIG_SH2_CRK	17	21	PF00017	0.429
LIG_SH2_NCK_1	489	493	PF00017	0.537
LIG_SH2_NCK_1	926	930	PF00017	0.475
LIG_SH2_PTP2	967	970	PF00017	0.466
LIG_SH2_STAP1	1345	1349	PF00017	0.298
LIG_SH2_STAP1	17	21	PF00017	0.429
LIG_SH2_STAP1	430	434	PF00017	0.497
LIG_SH2_STAP1	798	802	PF00017	0.408
LIG_SH2_STAT5	1051	1054	PF00017	0.429
LIG_SH2_STAT5	1057	1060	PF00017	0.381
LIG_SH2_STAT5	1339	1342	PF00017	0.339
LIG_SH2_STAT5	1345	1348	PF00017	0.339
LIG_SH2_STAT5	874	877	PF00017	0.515
LIG_SH2_STAT5	967	970	PF00017	0.406
LIG_SH3_3	1151	1157	PF00018	0.441
LIG_SH3_3	1298	1304	PF00018	0.339
LIG_SH3_3	395	401	PF00018	0.455
LIG_SH3_3	412	418	PF00018	0.543
LIG_SH3_3	493	499	PF00018	0.549
LIG_SH3_3	548	554	PF00018	0.482
LIG_SH3_3	626	632	PF00018	0.527
LIG_SH3_3	951	957	PF00018	0.463
LIG_SH3_3	993	999	PF00018	0.603
LIG_SUMO_SIM_anti_2	1110	1115	PF11976	0.358
LIG_SUMO_SIM_anti_2	1149	1156	PF11976	0.252
LIG_SUMO_SIM_anti_2	273	283	PF11976	0.494
LIG_SUMO_SIM_anti_2	341	347	PF11976	0.487
LIG_SUMO_SIM_anti_2	743	752	PF11976	0.474
LIG_SUMO_SIM_par_1	1119	1125	PF11976	0.485
LIG_SUMO_SIM_par_1	1149	1156	PF11976	0.396
LIG_SUMO_SIM_par_1	1218	1224	PF11976	0.441
LIG_SUMO_SIM_par_1	1355	1361	PF11976	0.433
LIG_SUMO_SIM_par_1	19	26	PF11976	0.406
LIG_SUMO_SIM_par_1	661	668	PF11976	0.433
LIG_TRAF2_1	1046	1049	PF00917	0.449
LIG_TRAF2_1	12	15	PF00917	0.550
LIG_TRAF2_1	1232	1235	PF00917	0.431
LIG_TRAF2_1	1253	1256	PF00917	0.460
LIG_TRAF2_1	144	147	PF00917	0.434
LIG_TRAF2_1	233	236	PF00917	0.534
LIG_TYR_ITSM	963	970	PF00017	0.502
LIG_UBA3_1	1025	1031	PF00899	0.444
LIG_UBA3_1	405	413	PF00899	0.450
LIG_UBA3_1	716	723	PF00899	0.531
LIG_WRC_WIRS_1	564	569	PF05994	0.502
LIG_WRC_WIRS_1	666	671	PF05994	0.461
MOD_CDK_SPK_2	1297	1302	PF00069	0.339
MOD_CDK_SPK_2	288	293	PF00069	0.468
MOD_CDK_SPK_2	995	1000	PF00069	0.615
MOD_CDK_SPxK_1	608	614	PF00069	0.592
MOD_CDK_SPxxK_3	1024	1031	PF00069	0.443
MOD_CK1_1	103	109	PF00069	0.548
MOD_CK1_1	1044	1050	PF00069	0.550
MOD_CK1_1	1265	1271	PF00069	0.404
MOD_CK1_1	1332	1338	PF00069	0.346
MOD_CK1_1	195	201	PF00069	0.492
MOD_CK1_1	254	260	PF00069	0.617
MOD_CK1_1	320	326	PF00069	0.493
MOD_CK1_1	627	633	PF00069	0.555
MOD_CK1_1	75	81	PF00069	0.427
MOD_CK1_1	759	765	PF00069	0.601
MOD_CK1_1	830	836	PF00069	0.526
MOD_CK1_1	855	861	PF00069	0.413
MOD_CK1_1	989	995	PF00069	0.592
MOD_CK2_1	1147	1153	PF00069	0.307
MOD_CK2_1	1167	1173	PF00069	0.367
MOD_CK2_1	1200	1206	PF00069	0.497
MOD_CK2_1	1218	1224	PF00069	0.221
MOD_CK2_1	1229	1235	PF00069	0.312
MOD_CK2_1	1250	1256	PF00069	0.412
MOD_CK2_1	1321	1327	PF00069	0.466
MOD_CK2_1	16	22	PF00069	0.482
MOD_CK2_1	195	201	PF00069	0.493
MOD_CK2_1	230	236	PF00069	0.669
MOD_CK2_1	383	389	PF00069	0.618
MOD_CK2_1	463	469	PF00069	0.484
MOD_CK2_1	655	661	PF00069	0.440
MOD_CK2_1	665	671	PF00069	0.378
MOD_CK2_1	789	795	PF00069	0.511
MOD_CK2_1	88	94	PF00069	0.487
MOD_Cter_Amidation	1361	1364	PF01082	0.364
MOD_Cter_Amidation	240	243	PF01082	0.742
MOD_GlcNHglycan	1043	1046	PF01048	0.563
MOD_GlcNHglycan	1053	1057	PF01048	0.484
MOD_GlcNHglycan	109	112	PF01048	0.292
MOD_GlcNHglycan	1264	1267	PF01048	0.421
MOD_GlcNHglycan	128	131	PF01048	0.526
MOD_GlcNHglycan	175	178	PF01048	0.414
MOD_GlcNHglycan	179	182	PF01048	0.423
MOD_GlcNHglycan	262	265	PF01048	0.641
MOD_GlcNHglycan	319	322	PF01048	0.539
MOD_GlcNHglycan	359	362	PF01048	0.621
MOD_GlcNHglycan	519	523	PF01048	0.466
MOD_GlcNHglycan	6	10	PF01048	0.518
MOD_GlcNHglycan	781	785	PF01048	0.386
MOD_GlcNHglycan	829	832	PF01048	0.526
MOD_GlcNHglycan	837	840	PF01048	0.473
MOD_GlcNHglycan	854	857	PF01048	0.249
MOD_GlcNHglycan	90	93	PF01048	0.475
MOD_GlcNHglycan	927	930	PF01048	0.464
MOD_GlcNHglycan	988	991	PF01048	0.598
MOD_GSK3_1	103	110	PF00069	0.536
MOD_GSK3_1	1155	1162	PF00069	0.348
MOD_GSK3_1	1182	1189	PF00069	0.466
MOD_GSK3_1	1258	1265	PF00069	0.494
MOD_GSK3_1	173	180	PF00069	0.463
MOD_GSK3_1	195	202	PF00069	0.454
MOD_GSK3_1	227	234	PF00069	0.528
MOD_GSK3_1	297	304	PF00069	0.456
MOD_GSK3_1	357	364	PF00069	0.603
MOD_GSK3_1	608	615	PF00069	0.549
MOD_GSK3_1	624	631	PF00069	0.520
MOD_GSK3_1	639	646	PF00069	0.512
MOD_GSK3_1	72	79	PF00069	0.383
MOD_GSK3_1	755	762	PF00069	0.494
MOD_GSK3_1	800	807	PF00069	0.503
MOD_GSK3_1	827	834	PF00069	0.538
MOD_GSK3_1	835	842	PF00069	0.427
MOD_GSK3_1	896	903	PF00069	0.466
MOD_LATS_1	555	561	PF00433	0.522
MOD_N-GLC_1	1364	1369	PF02516	0.339
MOD_N-GLC_1	254	259	PF02516	0.546
MOD_N-GLC_2	1334	1336	PF02516	0.339
MOD_N-GLC_2	150	152	PF02516	0.468
MOD_N-GLC_2	780	782	PF02516	0.299
MOD_NEK2_1	1018	1023	PF00069	0.401
MOD_NEK2_1	112	117	PF00069	0.464
MOD_NEK2_1	1147	1152	PF00069	0.405
MOD_NEK2_1	1159	1164	PF00069	0.325
MOD_NEK2_1	1186	1191	PF00069	0.436
MOD_NEK2_1	1197	1202	PF00069	0.447
MOD_NEK2_1	1276	1281	PF00069	0.364
MOD_NEK2_1	151	156	PF00069	0.423
MOD_NEK2_1	173	178	PF00069	0.393
MOD_NEK2_1	192	197	PF00069	0.229
MOD_NEK2_1	298	303	PF00069	0.460
MOD_NEK2_1	421	426	PF00069	0.583
MOD_NEK2_1	440	445	PF00069	0.446
MOD_NEK2_1	716	721	PF00069	0.426
MOD_NEK2_1	800	805	PF00069	0.510
MOD_NEK2_1	816	821	PF00069	0.466
MOD_NEK2_1	900	905	PF00069	0.440
MOD_NEK2_1	908	913	PF00069	0.401
MOD_NEK2_2	680	685	PF00069	0.518
MOD_NEK2_2	976	981	PF00069	0.449
MOD_PIKK_1	1001	1007	PF00454	0.696
MOD_PIKK_1	1044	1050	PF00454	0.436
MOD_PIKK_1	756	762	PF00454	0.520
MOD_PIKK_1	817	823	PF00454	0.504
MOD_PIKK_1	947	953	PF00454	0.327
MOD_PK_1	606	612	PF00069	0.579
MOD_PK_1	72	78	PF00069	0.261
MOD_PKA_1	248	254	PF00069	0.685
MOD_PKA_1	432	438	PF00069	0.568
MOD_PKA_1	457	463	PF00069	0.518
MOD_PKA_1	605	611	PF00069	0.558
MOD_PKA_2	195	201	PF00069	0.514
MOD_PKA_2	260	266	PF00069	0.632
MOD_PKA_2	298	304	PF00069	0.504
MOD_PKA_2	339	345	PF00069	0.543
MOD_PKA_2	432	438	PF00069	0.534
MOD_PKA_2	440	446	PF00069	0.461
MOD_PKA_2	457	463	PF00069	0.399
MOD_PKA_2	605	611	PF00069	0.578
MOD_PKA_2	680	686	PF00069	0.419
MOD_PKA_2	694	700	PF00069	0.445
MOD_PKA_2	734	740	PF00069	0.565
MOD_PKA_2	756	762	PF00069	0.566
MOD_PKA_2	827	833	PF00069	0.508
MOD_PKA_2	864	870	PF00069	0.432
MOD_PKA_2	94	100	PF00069	0.552
MOD_PKB_1	246	254	PF00069	0.686
MOD_Plk_1	1032	1038	PF00069	0.551
MOD_Plk_1	1052	1058	PF00069	0.484
MOD_Plk_1	1234	1240	PF00069	0.339
MOD_Plk_1	1326	1332	PF00069	0.339
MOD_Plk_1	156	162	PF00069	0.460
MOD_Plk_1	518	524	PF00069	0.431
MOD_Plk_1	56	62	PF00069	0.443
MOD_Plk_1	896	902	PF00069	0.543
MOD_Plk_2-3	665	671	PF00069	0.481
MOD_Plk_4	1147	1153	PF00069	0.399
MOD_Plk_4	1182	1188	PF00069	0.428
MOD_Plk_4	1197	1203	PF00069	0.462
MOD_Plk_4	1218	1224	PF00069	0.358
MOD_Plk_4	1276	1282	PF00069	0.441
MOD_Plk_4	151	157	PF00069	0.523
MOD_Plk_4	16	22	PF00069	0.391
MOD_Plk_4	298	304	PF00069	0.454
MOD_Plk_4	341	347	PF00069	0.357
MOD_Plk_4	540	546	PF00069	0.502
MOD_Plk_4	56	62	PF00069	0.474
MOD_Plk_4	563	569	PF00069	0.545
MOD_Plk_4	590	596	PF00069	0.473
MOD_Plk_4	716	722	PF00069	0.473
MOD_Plk_4	896	902	PF00069	0.529
MOD_Plk_4	903	909	PF00069	0.410
MOD_Plk_4	983	989	PF00069	0.518
MOD_ProDKin_1	1024	1030	PF00069	0.442
MOD_ProDKin_1	1136	1142	PF00069	0.464
MOD_ProDKin_1	1297	1303	PF00069	0.339
MOD_ProDKin_1	227	233	PF00069	0.619
MOD_ProDKin_1	288	294	PF00069	0.476
MOD_ProDKin_1	414	420	PF00069	0.565
MOD_ProDKin_1	570	576	PF00069	0.513
MOD_ProDKin_1	608	614	PF00069	0.580
MOD_ProDKin_1	628	634	PF00069	0.517
MOD_ProDKin_1	855	861	PF00069	0.491
MOD_ProDKin_1	880	886	PF00069	0.493
MOD_ProDKin_1	995	1001	PF00069	0.653
MOD_SUMO_rev_2	1055	1064	PF00179	0.466
TRG_DiLeu_BaEn_1	1235	1240	PF01217	0.473
TRG_DiLeu_BaEn_1	277	282	PF01217	0.572
TRG_DiLeu_BaEn_1	399	404	PF01217	0.476
TRG_DiLeu_BaEn_1	849	854	PF01217	0.543
TRG_DiLeu_BaLyEn_6	1116	1121	PF01217	0.485
TRG_DiLeu_BaLyEn_6	1351	1356	PF01217	0.339
TRG_DiLeu_BaLyEn_6	208	213	PF01217	0.519
TRG_DiLeu_BaLyEn_6	398	403	PF01217	0.468
TRG_DiLeu_BaLyEn_6	571	576	PF01217	0.515
TRG_DiLeu_BaLyEn_6	630	635	PF01217	0.629
TRG_DiLeu_BaLyEn_6	918	923	PF01217	0.488
TRG_DiLeu_BaLyEn_6	95	100	PF01217	0.477
TRG_ENDOCYTIC_2	1051	1054	PF00928	0.407
TRG_ENDOCYTIC_2	1339	1342	PF00928	0.339
TRG_ENDOCYTIC_2	17	20	PF00928	0.355
TRG_ENDOCYTIC_2	967	970	PF00928	0.420
TRG_ER_diArg_1	432	434	PF00400	0.532
TRG_ER_diArg_1	439	442	PF00400	0.492
TRG_ER_diArg_1	604	606	PF00400	0.556
TRG_ER_diArg_1	621	623	PF00400	0.618
TRG_ER_diArg_1	648	650	PF00400	0.566
TRG_ER_diArg_1	920	922	PF00400	0.493
TRG_ER_diArg_1	973	975	PF00400	0.422
TRG_NES_CRM1_1	1165	1175	PF08389	0.252
TRG_NES_CRM1_1	1195	1210	PF08389	0.408
TRG_NLS_MonoCore_2	245	250	PF00514	0.741
TRG_NLS_MonoExtC_3	241	246	PF00514	0.667
TRG_NLS_MonoExtN_4	242	247	PF00514	0.674
TRG_Pf-PMV_PEXEL_1	1016	1020	PF00026	0.477
TRG_Pf-PMV_PEXEL_1	1167	1171	PF00026	0.408
TRG_Pf-PMV_PEXEL_1	190	194	PF00026	0.496
TRG_Pf-PMV_PEXEL_1	214	218	PF00026	0.480
TRG_Pf-PMV_PEXEL_1	479	483	PF00026	0.494
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.495
TRG_Pf-PMV_PEXEL_1	736	740	PF00026	0.525
TRG_Pf-PMV_PEXEL_1	946	951	PF00026	0.332

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILS0	Leptomonas seymouri	59%	99%
A0A1X0PAF7	Trypanosomatidae	30%	100%
A0A3Q8INT8	Leishmania donovani	93%	100%
A0A3R7KJ27	Trypanosoma rangeli	30%	100%
A4HBB9	Leishmania braziliensis	78%	100%
A4IAG7	Leishmania infantum	93%	100%
E9B5J1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
V5BLT4	Trypanosoma cruzi	30%	100%