Robl_LC7 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q2B8_LEIMA

TriTrypDb:

LmjF.34.4230 , LMJLV39_340048900 , LMJSD75_340049300

Length:

180

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q2B8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q2B8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	15	19	PF00656	0.647
CLV_C14_Caspase3-7	159	163	PF00656	0.492
CLV_NRD_NRD_1	61	63	PF00675	0.666
CLV_PCSK_KEX2_1	144	146	PF00082	0.656
CLV_PCSK_KEX2_1	172	174	PF00082	0.661
CLV_PCSK_PC1ET2_1	144	146	PF00082	0.656
CLV_PCSK_PC1ET2_1	172	174	PF00082	0.661
CLV_PCSK_SKI1_1	122	126	PF00082	0.607
CLV_PCSK_SKI1_1	144	148	PF00082	0.590
CLV_PCSK_SKI1_1	62	66	PF00082	0.657
DEG_SPOP_SBC_1	103	107	PF00917	0.550
DOC_MAPK_gen_1	144	150	PF00069	0.639
DOC_PP4_FxxP_1	57	60	PF00568	0.692
DOC_USP7_MATH_1	39	43	PF00917	0.791
DOC_USP7_MATH_1	51	55	PF00917	0.689
DOC_WW_Pin1_4	30	35	PF00397	0.695
LIG_14-3-3_CanoR_1	145	149	PF00244	0.629
LIG_14-3-3_CanoR_1	20	25	PF00244	0.686
LIG_14-3-3_CanoR_1	79	86	PF00244	0.723
LIG_BRCT_BRCA1_1	113	117	PF00533	0.646
LIG_BRCT_BRCA1_1	53	57	PF00533	0.673
LIG_FHA_1	75	81	PF00498	0.598
LIG_FHA_2	13	19	PF00498	0.597
LIG_FHA_2	157	163	PF00498	0.615
LIG_LIR_Apic_2	54	60	PF02991	0.659
LIG_LIR_Gen_1	147	157	PF02991	0.625
LIG_LIR_Nem_3	147	153	PF02991	0.639
LIG_LIR_Nem_3	165	170	PF02991	0.313
LIG_SH2_CRK	127	131	PF00017	0.476
LIG_SH2_CRK	167	171	PF00017	0.614
LIG_SH2_STAT5	155	158	PF00017	0.489
LIG_SH2_STAT5	36	39	PF00017	0.762
LIG_SH3_3	25	31	PF00018	0.778
LIG_SUMO_SIM_anti_2	84	91	PF11976	0.522
LIG_TYR_ITIM	125	130	PF00017	0.610
LIG_TYR_ITSM	163	170	PF00017	0.645
MOD_CK1_1	11	17	PF00069	0.687
MOD_CK1_1	42	48	PF00069	0.793
MOD_CK1_1	84	90	PF00069	0.651
MOD_GlcNHglycan	106	109	PF01048	0.659
MOD_GlcNHglycan	112	116	PF01048	0.552
MOD_GlcNHglycan	133	136	PF01048	0.559
MOD_GlcNHglycan	162	165	PF01048	0.659
MOD_GlcNHglycan	37	40	PF01048	0.582
MOD_GSK3_1	156	163	PF00069	0.619
MOD_GSK3_1	16	23	PF00069	0.649
MOD_GSK3_1	172	179	PF00069	0.437
MOD_GSK3_1	35	42	PF00069	0.560
MOD_GSK3_1	7	14	PF00069	0.713
MOD_GSK3_1	74	81	PF00069	0.633
MOD_NEK2_1	104	109	PF00069	0.636
MOD_NEK2_1	74	79	PF00069	0.635
MOD_PIKK_1	81	87	PF00454	0.702
MOD_PKA_1	144	150	PF00069	0.639
MOD_PKA_1	172	178	PF00069	0.704
MOD_PKA_2	144	150	PF00069	0.639
MOD_PKA_2	16	22	PF00069	0.650
MOD_PKA_2	172	178	PF00069	0.704
MOD_PKA_2	42	48	PF00069	0.810
MOD_PKA_2	78	84	PF00069	0.756
MOD_Plk_4	162	168	PF00069	0.651
MOD_Plk_4	84	90	PF00069	0.651
MOD_ProDKin_1	30	36	PF00069	0.697
MOD_SUMO_for_1	138	141	PF00179	0.701
TRG_ENDOCYTIC_2	127	130	PF00928	0.470
TRG_ENDOCYTIC_2	167	170	PF00928	0.616
TRG_ER_diArg_1	40	43	PF00400	0.651

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9B5L8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	77%