LeishMANIAdb
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
Gene product:
NADH:ubiquinone oxidoreductase, ESSS subunit, putative
Species:
Leishmania major
UniProt:
Q4Q291_LEIMA
TriTrypDb:
LmjF.34.4440 , LMJLV39_340049900 , LMJSD75_340050200
Length:
112

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0005747 mitochondrial respiratory chain complex I 4 2
GO:0030964 NADH dehydrogenase complex 3 2
GO:0032991 protein-containing complex 1 2
GO:0045271 respiratory chain complex I 4 2
GO:0098796 membrane protein complex 2 2
GO:0098798 mitochondrial protein-containing complex 2 2
GO:0098800 inner mitochondrial membrane protein complex 3 2
GO:0098803 respiratory chain complex 3 2
GO:1902494 catalytic complex 2 2
GO:1902495 transmembrane transporter complex 3 2
GO:1990204 oxidoreductase complex 3 2
GO:1990351 transporter complex 2 2
GO:0016020 membrane 2 8
GO:0110165 cellular anatomical entity 1 8

Expansion

Sequence features

Q4Q291
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q291

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 14 16 PF00675 0.586
CLV_NRD_NRD_1 19 21 PF00675 0.592
CLV_NRD_NRD_1 84 86 PF00675 0.268
CLV_NRD_NRD_1 89 91 PF00675 0.265
CLV_PCSK_FUR_1 87 91 PF00082 0.260
CLV_PCSK_KEX2_1 14 16 PF00082 0.586
CLV_PCSK_KEX2_1 19 21 PF00082 0.592
CLV_PCSK_KEX2_1 84 86 PF00082 0.261
CLV_PCSK_KEX2_1 89 91 PF00082 0.261
CLV_PCSK_PC7_1 15 21 PF00082 0.593
CLV_PCSK_PC7_1 85 91 PF00082 0.260
CLV_PCSK_SKI1_1 7 11 PF00082 0.582
DEG_SCF_FBW7_1 30 36 PF00400 0.405
DOC_CKS1_1 30 35 PF01111 0.406
DOC_MAPK_gen_1 87 97 PF00069 0.460
DOC_MAPK_MEF2A_6 49 57 PF00069 0.303
DOC_PP1_RVXF_1 17 24 PF00149 0.399
DOC_WW_Pin1_4 29 34 PF00397 0.410
LIG_14-3-3_CanoR_1 34 38 PF00244 0.279
LIG_Clathr_ClatBox_1 95 99 PF01394 0.460
LIG_deltaCOP1_diTrp_1 42 51 PF00928 0.261
LIG_LIR_Nem_3 16 21 PF02991 0.390
LIG_Pex14_2 37 41 PF04695 0.261
LIG_SH2_CRK 68 72 PF00017 0.479
LIG_SH2_STAT5 31 34 PF00017 0.413
LIG_SH3_3 27 33 PF00018 0.408
LIG_SUMO_SIM_anti_2 94 99 PF11976 0.462
LIG_TRAF2_1 78 81 PF00917 0.469
MOD_CDK_SPK_2 29 34 PF00069 0.428
MOD_CMANNOS 41 44 PF00535 0.461
MOD_GSK3_1 29 36 PF00069 0.404
MOD_GSK3_1 66 73 PF00069 0.329
MOD_NEK2_1 13 18 PF00069 0.395
MOD_NEK2_2 33 38 PF00069 0.261
MOD_PKA_2 13 19 PF00069 0.389
MOD_PKA_2 33 39 PF00069 0.155
MOD_ProDKin_1 29 35 PF00069 0.406
TRG_DiLeu_BaEn_1 91 96 PF01217 0.464
TRG_ENDOCYTIC_2 68 71 PF00928 0.479
TRG_ER_diArg_1 13 15 PF00400 0.393
TRG_ER_diArg_1 18 20 PF00400 0.391
TRG_ER_diArg_1 83 85 PF00400 0.461
TRG_ER_diArg_1 86 89 PF00400 0.461

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P2D2 Leptomonas seymouri 95% 100%
A0A0S4IKM0 Bodo saltans 81% 100%
A0A1X0PB38 Trypanosomatidae 90% 100%
A0A3Q8IFX1 Leishmania donovani 98% 100%
A4HBF4 Leishmania braziliensis 99% 100%
A4IAK3 Leishmania infantum 98% 100%
C9ZLN8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 89% 100%
E9B5M7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS