SUZ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q240_LEIMA

TriTrypDb:

LmjF.36.0380 , LMJLV39_360009100 , LMJSD75_360008900

Length:

184

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 1, no: 5
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q240

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q240

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	132	134	PF00675	0.450
CLV_NRD_NRD_1	178	180	PF00675	0.473
CLV_NRD_NRD_1	181	183	PF00675	0.513
CLV_NRD_NRD_1	61	63	PF00675	0.456
CLV_PCSK_KEX2_1	130	132	PF00082	0.460
CLV_PCSK_KEX2_1	60	62	PF00082	0.453
CLV_PCSK_PC1ET2_1	130	132	PF00082	0.460
CLV_PCSK_PC7_1	57	63	PF00082	0.446
CLV_PCSK_SKI1_1	12	16	PF00082	0.415
CLV_PCSK_SKI1_1	62	66	PF00082	0.463
DEG_Nend_UBRbox_2	1	3	PF02207	0.474
DOC_PP1_RVXF_1	10	17	PF00149	0.431
DOC_USP7_MATH_1	101	105	PF00917	0.663
DOC_USP7_MATH_1	117	121	PF00917	0.468
DOC_USP7_MATH_1	143	147	PF00917	0.601
DOC_USP7_MATH_1	8	12	PF00917	0.438
DOC_USP7_MATH_1	93	97	PF00917	0.649
DOC_USP7_UBL2_3	176	180	PF12436	0.473
DOC_WW_Pin1_4	144	149	PF00397	0.656
DOC_WW_Pin1_4	75	80	PF00397	0.684
DOC_WW_Pin1_4	91	96	PF00397	0.525
LIG_FHA_1	21	27	PF00498	0.417
LIG_HP1_1	28	32	PF01393	0.422
LIG_SH2_STAT3	106	109	PF00017	0.693
LIG_SH2_STAT3	121	124	PF00017	0.360
LIG_SH2_STAT5	121	124	PF00017	0.440
LIG_SH2_STAT5	84	87	PF00017	0.593
LIG_UBA3_1	122	130	PF00899	0.440
MOD_CK1_1	102	108	PF00069	0.675
MOD_CK1_1	94	100	PF00069	0.628
MOD_CK2_1	169	175	PF00069	0.625
MOD_GlcNHglycan	101	104	PF01048	0.625
MOD_GlcNHglycan	106	109	PF01048	0.626
MOD_GlcNHglycan	141	144	PF01048	0.647
MOD_GlcNHglycan	18	21	PF01048	0.485
MOD_GlcNHglycan	6	9	PF01048	0.503
MOD_GlcNHglycan	96	99	PF01048	0.611
MOD_GSK3_1	135	142	PF00069	0.587
MOD_GSK3_1	16	23	PF00069	0.419
MOD_GSK3_1	4	11	PF00069	0.542
MOD_GSK3_1	80	87	PF00069	0.600
MOD_NEK2_1	16	21	PF00069	0.454
MOD_NEK2_2	20	25	PF00069	0.419
MOD_PIKK_1	111	117	PF00454	0.457
MOD_PIKK_1	154	160	PF00454	0.628
MOD_PIKK_1	163	169	PF00454	0.599
MOD_Plk_1	169	175	PF00069	0.522
MOD_Plk_1	87	93	PF00069	0.604
MOD_Plk_4	117	123	PF00069	0.500
MOD_Plk_4	80	86	PF00069	0.660
MOD_ProDKin_1	144	150	PF00069	0.660
MOD_ProDKin_1	75	81	PF00069	0.685
MOD_ProDKin_1	91	97	PF00069	0.525
TRG_DiLeu_BaLyEn_6	151	156	PF01217	0.549
TRG_ER_diArg_1	131	133	PF00400	0.448
TRG_ER_diArg_1	60	62	PF00400	0.453
TRG_NLS_MonoExtC_3	178	183	PF00514	0.536
TRG_NLS_MonoExtN_4	176	183	PF00514	0.478

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7D8	Leptomonas seymouri	48%	98%
A0A3S7XA93	Leishmania donovani	92%	100%
A4HNP6	Leishmania braziliensis	74%	100%
A4ICU9	Leishmania infantum	92%	100%
E9ASF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%