Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q233_LEIMA

TriTrypDb:

LmjF.36.0450 , LMJLV39_360009900 , LMJSD75_360009800

Length:

819

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q233

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q233

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	464	468	PF00656	0.421
CLV_C14_Caspase3-7	601	605	PF00656	0.424
CLV_C14_Caspase3-7	61	65	PF00656	0.610
CLV_C14_Caspase3-7	660	664	PF00656	0.410
CLV_C14_Caspase3-7	799	803	PF00656	0.392
CLV_NRD_NRD_1	154	156	PF00675	0.390
CLV_NRD_NRD_1	570	572	PF00675	0.630
CLV_NRD_NRD_1	670	672	PF00675	0.633
CLV_NRD_NRD_1	679	681	PF00675	0.631
CLV_PCSK_KEX2_1	154	156	PF00082	0.390
CLV_PCSK_KEX2_1	187	189	PF00082	0.295
CLV_PCSK_KEX2_1	570	572	PF00082	0.630
CLV_PCSK_KEX2_1	670	672	PF00082	0.633
CLV_PCSK_KEX2_1	679	681	PF00082	0.631
CLV_PCSK_PC1ET2_1	187	189	PF00082	0.295
CLV_PCSK_PC7_1	150	156	PF00082	0.377
CLV_PCSK_SKI1_1	187	191	PF00082	0.199
CLV_PCSK_SKI1_1	373	377	PF00082	0.290
CLV_PCSK_SKI1_1	415	419	PF00082	0.199
CLV_PCSK_SKI1_1	740	744	PF00082	0.630
CLV_PCSK_SKI1_1	769	773	PF00082	0.627
DEG_APCC_DBOX_1	27	35	PF00400	0.586
DEG_APCC_DBOX_1	372	380	PF00400	0.487
DEG_SPOP_SBC_1	319	323	PF00917	0.585
DEG_SPOP_SBC_1	527	531	PF00917	0.417
DEG_SPOP_SBC_1	586	590	PF00917	0.424
DEG_SPOP_SBC_1	723	727	PF00917	0.434
DOC_CYCLIN_RxL_1	235	248	PF00134	0.494
DOC_CYCLIN_yClb3_PxF_3	121	127	PF00134	0.364
DOC_CYCLIN_yCln2_LP_2	123	129	PF00134	0.366
DOC_CYCLIN_yCln2_LP_2	243	249	PF00134	0.503
DOC_MAPK_DCC_7	21	29	PF00069	0.596
DOC_MAPK_gen_1	21	29	PF00069	0.596
DOC_MAPK_gen_1	370	378	PF00069	0.492
DOC_MAPK_MEF2A_6	23	31	PF00069	0.591
DOC_MAPK_MEF2A_6	370	378	PF00069	0.492
DOC_PP1_RVXF_1	186	193	PF00149	0.400
DOC_PP1_RVXF_1	239	246	PF00149	0.486
DOC_PP2B_LxvP_1	123	126	PF13499	0.363
DOC_PP2B_LxvP_1	227	230	PF13499	0.199
DOC_PP2B_LxvP_1	249	252	PF13499	0.534
DOC_PP2B_LxvP_1	292	295	PF13499	0.588
DOC_PP4_FxxP_1	90	93	PF00568	0.199
DOC_USP7_MATH_1	283	287	PF00917	0.596
DOC_USP7_MATH_1	320	324	PF00917	0.586
DOC_USP7_MATH_1	422	426	PF00917	0.199
DOC_USP7_MATH_1	432	436	PF00917	0.400
DOC_USP7_MATH_1	490	494	PF00917	0.421
DOC_USP7_MATH_1	496	500	PF00917	0.417
DOC_USP7_MATH_1	526	530	PF00917	0.417
DOC_USP7_MATH_1	612	616	PF00917	0.419
DOC_USP7_MATH_1	652	656	PF00917	0.411
DOC_USP7_MATH_1	691	695	PF00917	0.403
DOC_USP7_MATH_1	722	726	PF00917	0.428
DOC_USP7_MATH_1	729	733	PF00917	0.426
DOC_USP7_MATH_1	792	796	PF00917	0.412
DOC_USP7_MATH_1	93	97	PF00917	0.199
DOC_WW_Pin1_4	125	130	PF00397	0.367
DOC_WW_Pin1_4	22	27	PF00397	0.594
DOC_WW_Pin1_4	250	255	PF00397	0.535
DOC_WW_Pin1_4	358	363	PF00397	0.598
DOC_WW_Pin1_4	457	462	PF00397	0.405
DOC_WW_Pin1_4	505	510	PF00397	0.423
DOC_WW_Pin1_4	641	646	PF00397	0.419
DOC_WW_Pin1_4	65	70	PF00397	0.594
DOC_WW_Pin1_4	653	658	PF00397	0.407
DOC_WW_Pin1_4	689	694	PF00397	0.409
DOC_WW_Pin1_4	761	766	PF00397	0.418
LIG_14-3-3_CanoR_1	154	158	PF00244	0.593
LIG_14-3-3_CanoR_1	28	32	PF00244	0.588
LIG_14-3-3_CanoR_1	334	338	PF00244	0.582
LIG_14-3-3_CanoR_1	354	362	PF00244	0.603
LIG_14-3-3_CanoR_1	403	408	PF00244	0.487
LIG_14-3-3_CanoR_1	436	444	PF00244	0.408
LIG_14-3-3_CanoR_1	489	495	PF00244	0.420
LIG_14-3-3_CanoR_1	560	568	PF00244	0.431
LIG_14-3-3_CanoR_1	740	748	PF00244	0.428
LIG_14-3-3_CanoR_1	755	765	PF00244	0.421
LIG_14-3-3_CanoR_1	769	774	PF00244	0.420
LIG_14-3-3_CanoR_1	79	86	PF00244	0.578
LIG_BIR_III_4	736	740	PF00653	0.433
LIG_BRCT_BRCA1_1	111	115	PF00533	0.371
LIG_BRCT_BRCA1_1	222	226	PF00533	0.199
LIG_BRCT_BRCA1_1	236	240	PF00533	0.490
LIG_DLG_GKlike_1	403	410	PF00625	0.490
LIG_FHA_1	102	108	PF00498	0.434
LIG_FHA_1	160	166	PF00498	0.591
LIG_FHA_1	260	266	PF00498	0.539
LIG_FHA_1	319	325	PF00498	0.584
LIG_FHA_1	412	418	PF00498	0.541
LIG_FHA_1	421	427	PF00498	0.199
LIG_FHA_1	45	51	PF00498	0.620
LIG_FHA_1	563	569	PF00498	0.429
LIG_FHA_1	743	749	PF00498	0.427
LIG_FHA_2	367	373	PF00498	0.503
LIG_FHA_2	390	396	PF00498	0.485
LIG_FHA_2	619	625	PF00498	0.433
LIG_FHA_2	658	664	PF00498	0.410
LIG_FHA_2	744	750	PF00498	0.424
LIG_LIR_Apic_2	87	93	PF02991	0.400
LIG_LIR_Gen_1	173	183	PF02991	0.561
LIG_LIR_Gen_1	260	269	PF02991	0.535
LIG_LIR_Nem_3	173	179	PF02991	0.566
LIG_LIR_Nem_3	237	243	PF02991	0.486
LIG_LIR_Nem_3	260	266	PF02991	0.539
LIG_LIR_Nem_3	442	447	PF02991	0.408
LIG_LIR_Nem_3	801	807	PF02991	0.359
LIG_LIR_Nem_3	96	101	PF02991	0.199
LIG_MLH1_MIPbox_1	222	226	PF16413	0.199
LIG_MYND_1	121	125	PF01753	0.359
LIG_NRBOX	374	380	PF00104	0.487
LIG_Pex14_2	222	226	PF04695	0.199
LIG_SH2_CRK	176	180	PF00017	0.561
LIG_SH2_CRK	444	448	PF00017	0.402
LIG_SH2_NCK_1	172	176	PF00017	0.571
LIG_SH2_NCK_1	659	663	PF00017	0.410
LIG_SH2_NCK_1	758	762	PF00017	0.427
LIG_SH2_STAP1	172	176	PF00017	0.571
LIG_SH2_STAP1	261	265	PF00017	0.538
LIG_SH2_STAP1	758	762	PF00017	0.427
LIG_SH2_STAP1	807	811	PF00017	0.302
LIG_SH2_STAT3	380	383	PF00017	0.484
LIG_SH2_STAT3	481	484	PF00017	0.417
LIG_SH2_STAT5	172	175	PF00017	0.571
LIG_SH2_STAT5	225	228	PF00017	0.199
LIG_SH2_STAT5	261	264	PF00017	0.538
LIG_SH2_STAT5	331	334	PF00017	0.589
LIG_SH2_STAT5	659	662	PF00017	0.407
LIG_SH3_1	670	676	PF00018	0.424
LIG_SH3_3	118	124	PF00018	0.362
LIG_SH3_3	126	132	PF00018	0.359
LIG_SH3_3	248	254	PF00018	0.535
LIG_SH3_3	301	307	PF00018	0.588
LIG_SH3_3	538	544	PF00018	0.419
LIG_SH3_3	639	645	PF00018	0.421
LIG_SH3_3	66	72	PF00018	0.590
LIG_SH3_3	662	668	PF00018	0.407
LIG_SH3_3	670	676	PF00018	0.424
LIG_SH3_3	762	768	PF00018	0.412
LIG_SUMO_SIM_anti_2	135	140	PF11976	0.199
LIG_SUMO_SIM_par_1	268	274	PF11976	0.542
LIG_TRAF2_1	499	502	PF00917	0.427
LIG_WW_2	121	124	PF00397	0.425
MOD_CDC14_SPxK_1	25	28	PF00782	0.465
MOD_CDK_SPxK_1	22	28	PF00069	0.473
MOD_CDK_SPxxK_3	252	259	PF00069	0.402
MOD_CK1_1	109	115	PF00069	0.435
MOD_CK1_1	137	143	PF00069	0.199
MOD_CK1_1	14	20	PF00069	0.477
MOD_CK1_1	271	277	PF00069	0.421
MOD_CK1_1	318	324	PF00069	0.462
MOD_CK1_1	329	335	PF00069	0.461
MOD_CK1_1	357	363	PF00069	0.478
MOD_CK1_1	411	417	PF00069	0.385
MOD_CK1_1	424	430	PF00069	0.199
MOD_CK1_1	435	441	PF00069	0.485
MOD_CK1_1	479	485	PF00069	0.503
MOD_CK1_1	511	517	PF00069	0.527
MOD_CK1_1	533	539	PF00069	0.517
MOD_CK1_1	548	554	PF00069	0.526
MOD_CK1_1	559	565	PF00069	0.524
MOD_CK1_1	577	583	PF00069	0.523
MOD_CK1_1	606	612	PF00069	0.506
MOD_CK1_1	615	621	PF00069	0.518
MOD_CK1_1	622	628	PF00069	0.526
MOD_CK1_1	644	650	PF00069	0.505
MOD_CK1_1	692	698	PF00069	0.487
MOD_CK1_1	727	733	PF00069	0.520
MOD_CK1_1	806	812	PF00069	0.348
MOD_CK2_1	297	303	PF00069	0.475
MOD_CK2_1	358	364	PF00069	0.478
MOD_CK2_1	389	395	PF00069	0.321
MOD_CK2_1	436	442	PF00069	0.488
MOD_CK2_1	49	55	PF00069	0.514
MOD_CK2_1	496	502	PF00069	0.510
MOD_CK2_1	711	717	PF00069	0.513
MOD_CK2_1	743	749	PF00069	0.517
MOD_Cter_Amidation	568	571	PF01082	0.519
MOD_DYRK1A_RPxSP_1	505	509	PF00069	0.512
MOD_GlcNHglycan	139	142	PF01048	0.199
MOD_GlcNHglycan	217	220	PF01048	0.199
MOD_GlcNHglycan	280	283	PF01048	0.477
MOD_GlcNHglycan	299	302	PF01048	0.475
MOD_GlcNHglycan	337	340	PF01048	0.461
MOD_GlcNHglycan	356	359	PF01048	0.484
MOD_GlcNHglycan	428	431	PF01048	0.199
MOD_GlcNHglycan	438	441	PF01048	0.483
MOD_GlcNHglycan	463	466	PF01048	0.509
MOD_GlcNHglycan	474	477	PF01048	0.499
MOD_GlcNHglycan	481	484	PF01048	0.503
MOD_GlcNHglycan	492	495	PF01048	0.506
MOD_GlcNHglycan	524	527	PF01048	0.520
MOD_GlcNHglycan	535	538	PF01048	0.515
MOD_GlcNHglycan	550	553	PF01048	0.533
MOD_GlcNHglycan	565	568	PF01048	0.523
MOD_GlcNHglycan	608	611	PF01048	0.502
MOD_GlcNHglycan	617	620	PF01048	0.523
MOD_GlcNHglycan	660	663	PF01048	0.496
MOD_GlcNHglycan	703	706	PF01048	0.491
MOD_GlcNHglycan	713	716	PF01048	0.515
MOD_GlcNHglycan	758	761	PF01048	0.518
MOD_GlcNHglycan	792	795	PF01048	0.499
MOD_GSK3_1	130	137	PF00069	0.384
MOD_GSK3_1	153	160	PF00069	0.474
MOD_GSK3_1	315	322	PF00069	0.467
MOD_GSK3_1	329	336	PF00069	0.458
MOD_GSK3_1	354	361	PF00069	0.485
MOD_GSK3_1	36	43	PF00069	0.473
MOD_GSK3_1	4	11	PF00069	0.461
MOD_GSK3_1	411	418	PF00069	0.390
MOD_GSK3_1	420	427	PF00069	0.199
MOD_GSK3_1	432	439	PF00069	0.481
MOD_GSK3_1	457	464	PF00069	0.493
MOD_GSK3_1	472	479	PF00069	0.500
MOD_GSK3_1	496	503	PF00069	0.510
MOD_GSK3_1	511	518	PF00069	0.527
MOD_GSK3_1	522	529	PF00069	0.517
MOD_GSK3_1	544	551	PF00069	0.516
MOD_GSK3_1	556	563	PF00069	0.524
MOD_GSK3_1	574	581	PF00069	0.522
MOD_GSK3_1	608	615	PF00069	0.502
MOD_GSK3_1	618	625	PF00069	0.526
MOD_GSK3_1	653	660	PF00069	0.490
MOD_GSK3_1	687	694	PF00069	0.499
MOD_GSK3_1	703	710	PF00069	0.493
MOD_GSK3_1	723	730	PF00069	0.526
MOD_GSK3_1	78	85	PF00069	0.450
MOD_GSK3_1	786	793	PF00069	0.507
MOD_GSK3_1	93	100	PF00069	0.199
MOD_LATS_1	413	419	PF00433	0.199
MOD_LATS_1	487	493	PF00433	0.506
MOD_LATS_1	558	564	PF00433	0.525
MOD_N-GLC_1	278	283	PF02516	0.471
MOD_N-GLC_1	545	550	PF02516	0.516
MOD_N-GLC_2	108	110	PF02516	0.429
MOD_NEK2_1	134	139	PF00069	0.199
MOD_NEK2_1	183	188	PF00069	0.368
MOD_NEK2_1	192	197	PF00069	0.199
MOD_NEK2_1	215	220	PF00069	0.199
MOD_NEK2_1	268	273	PF00069	0.396
MOD_NEK2_1	327	332	PF00069	0.462
MOD_NEK2_1	4	9	PF00069	0.461
MOD_NEK2_1	426	431	PF00069	0.199
MOD_NEK2_1	456	461	PF00069	0.481
MOD_NEK2_1	575	580	PF00069	0.524
MOD_NEK2_1	603	608	PF00069	0.508
MOD_NEK2_1	711	716	PF00069	0.513
MOD_NEK2_1	728	733	PF00069	0.519
MOD_NEK2_2	93	98	PF00069	0.199
MOD_OFUCOSY	103	110	PF10250	0.435
MOD_PIKK_1	159	165	PF00454	0.474
MOD_PIKK_1	622	628	PF00454	0.526
MOD_PIKK_1	78	84	PF00454	0.452
MOD_PKA_2	153	159	PF00069	0.471
MOD_PKA_2	27	33	PF00069	0.462
MOD_PKA_2	333	339	PF00069	0.458
MOD_PKA_2	408	414	PF00069	0.348
MOD_PKA_2	435	441	PF00069	0.485
MOD_PKA_2	488	494	PF00069	0.508
MOD_PKA_2	559	565	PF00069	0.524
MOD_PKA_2	754	760	PF00069	0.511
MOD_PKA_2	78	84	PF00069	0.452
MOD_PKB_1	738	746	PF00069	0.524
MOD_Plk_1	14	20	PF00069	0.477
MOD_Plk_1	259	265	PF00069	0.399
MOD_Plk_1	545	551	PF00069	0.519
MOD_Plk_1	603	609	PF00069	0.510
MOD_Plk_1	707	713	PF00069	0.501
MOD_Plk_1	743	749	PF00069	0.517
MOD_Plk_1	796	802	PF00069	0.480
MOD_Plk_4	134	140	PF00069	0.199
MOD_Plk_4	192	198	PF00069	0.199
MOD_Plk_4	245	251	PF00069	0.360
MOD_Plk_4	259	265	PF00069	0.399
MOD_Plk_4	268	274	PF00069	0.399
MOD_Plk_4	476	482	PF00069	0.502
MOD_Plk_4	93	99	PF00069	0.199
MOD_ProDKin_1	125	131	PF00069	0.427
MOD_ProDKin_1	22	28	PF00069	0.473
MOD_ProDKin_1	250	256	PF00069	0.393
MOD_ProDKin_1	358	364	PF00069	0.478
MOD_ProDKin_1	457	463	PF00069	0.489
MOD_ProDKin_1	505	511	PF00069	0.515
MOD_ProDKin_1	641	647	PF00069	0.508
MOD_ProDKin_1	65	71	PF00069	0.471
MOD_ProDKin_1	653	659	PF00069	0.490
MOD_ProDKin_1	689	695	PF00069	0.491
MOD_ProDKin_1	761	767	PF00069	0.505
MOD_SUMO_rev_2	590	600	PF00179	0.519
TRG_DiLeu_BaEn_1	371	376	PF01217	0.324
TRG_DiLeu_BaEn_2	259	265	PF01217	0.399
TRG_DiLeu_BaLyEn_6	185	190	PF01217	0.334
TRG_DiLeu_BaLyEn_6	374	379	PF01217	0.322
TRG_DiLeu_BaLyEn_6	571	576	PF01217	0.519
TRG_ENDOCYTIC_2	172	175	PF00928	0.439
TRG_ENDOCYTIC_2	176	179	PF00928	0.428
TRG_ENDOCYTIC_2	261	264	PF00928	0.393
TRG_ENDOCYTIC_2	444	447	PF00928	0.487
TRG_ENDOCYTIC_2	669	672	PF00928	0.527
TRG_ER_diArg_1	21	24	PF00400	0.486
TRG_ER_diArg_1	669	671	PF00400	0.525
TRG_ER_diArg_1	679	681	PF00400	0.524
TRG_Pf-PMV_PEXEL_1	377	382	PF00026	0.320