DNAJ protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNAJ protein-like protein

Species:

Leishmania major

UniProt:

Q4Q215_LEIMA

TriTrypDb:

LmjF.36.0610 , LMJLV39_360011800 , LMJSD75_360011700

Length:

261

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q215

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q215

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	147	149	PF00675	0.633
CLV_NRD_NRD_1	232	234	PF00675	0.335
CLV_PCSK_KEX2_1	189	191	PF00082	0.313
CLV_PCSK_KEX2_1	232	234	PF00082	0.335
CLV_PCSK_PC1ET2_1	189	191	PF00082	0.337
CLV_PCSK_SKI1_1	114	118	PF00082	0.556
CLV_PCSK_SKI1_1	194	198	PF00082	0.335
CLV_PCSK_SKI1_1	217	221	PF00082	0.335
DEG_APCC_DBOX_1	147	155	PF00400	0.705
DEG_APCC_DBOX_1	163	171	PF00400	0.391
DOC_CYCLIN_RxL_1	189	202	PF00134	0.335
DOC_MAPK_gen_1	162	170	PF00069	0.472
DOC_MAPK_gen_1	189	199	PF00069	0.331
DOC_PP4_FxxP_1	69	72	PF00568	0.591
DOC_USP7_MATH_1	181	185	PF00917	0.413
DOC_USP7_MATH_1	33	37	PF00917	0.593
DOC_USP7_MATH_1	52	56	PF00917	0.515
DOC_USP7_MATH_1	59	63	PF00917	0.749
DOC_USP7_UBL2_3	114	118	PF12436	0.545
DOC_USP7_UBL2_3	158	162	PF12436	0.524
DOC_USP7_UBL2_3	189	193	PF12436	0.453
DOC_USP7_UBL2_3	217	221	PF12436	0.335
DOC_WW_Pin1_4	50	55	PF00397	0.685
LIG_14-3-3_CanoR_1	148	152	PF00244	0.624
LIG_APCC_ABBA_1	197	202	PF00400	0.335
LIG_FHA_1	11	17	PF00498	0.681
LIG_FHA_2	148	154	PF00498	0.615
LIG_FHA_2	180	186	PF00498	0.335
LIG_LIR_Apic_2	66	72	PF02991	0.583
LIG_LIR_Nem_3	214	219	PF02991	0.335
LIG_LIR_Nem_3	80	86	PF02991	0.635
LIG_Rb_pABgroove_1	104	112	PF01858	0.687
LIG_SH2_CRK	174	178	PF00017	0.335
LIG_SH2_CRK	83	87	PF00017	0.691
LIG_SH2_NCK_1	121	125	PF00017	0.548
LIG_SH2_SRC	94	97	PF00017	0.572
LIG_SH2_STAP1	235	239	PF00017	0.470
LIG_SH2_STAT5	41	44	PF00017	0.599
LIG_SH2_STAT5	94	97	PF00017	0.594
LIG_SH3_3	23	29	PF00018	0.606
LIG_SH3_4	114	121	PF00018	0.636
LIG_TRAF2_1	183	186	PF00917	0.349
LIG_UBA3_1	109	117	PF00899	0.550
LIG_UBA3_1	215	221	PF00899	0.335
LIG_WRC_WIRS_1	1	6	PF05994	0.627
MOD_CK1_1	10	16	PF00069	0.561
MOD_CK1_1	123	129	PF00069	0.469
MOD_CK1_1	238	244	PF00069	0.619
MOD_CK1_1	44	50	PF00069	0.687
MOD_CK1_1	63	69	PF00069	0.566
MOD_CK2_1	123	129	PF00069	0.660
MOD_CK2_1	179	185	PF00069	0.335
MOD_CK2_1	224	230	PF00069	0.441
MOD_CK2_1	82	88	PF00069	0.668
MOD_Cter_Amidation	134	137	PF01082	0.608
MOD_GlcNHglycan	122	125	PF01048	0.480
MOD_GlcNHglycan	137	140	PF01048	0.634
MOD_GlcNHglycan	240	243	PF01048	0.604
MOD_GlcNHglycan	250	253	PF01048	0.475
MOD_GlcNHglycan	26	29	PF01048	0.719
MOD_GlcNHglycan	35	38	PF01048	0.575
MOD_GlcNHglycan	44	47	PF01048	0.572
MOD_GlcNHglycan	54	57	PF01048	0.567
MOD_GlcNHglycan	69	72	PF01048	0.591
MOD_GlcNHglycan	9	12	PF01048	0.543
MOD_GlcNHglycan	98	101	PF01048	0.591
MOD_GSK3_1	20	27	PF00069	0.549
MOD_GSK3_1	29	36	PF00069	0.564
MOD_GSK3_1	40	47	PF00069	0.588
MOD_GSK3_1	59	66	PF00069	0.522
MOD_GSK3_1	6	13	PF00069	0.642
MOD_GSK3_1	82	89	PF00069	0.625
MOD_N-GLC_1	24	29	PF02516	0.574
MOD_N-GLC_1	50	55	PF02516	0.659
MOD_N-GLC_1	59	64	PF02516	0.547
MOD_N-GLC_1	6	11	PF02516	0.704
MOD_NEK2_1	110	115	PF00069	0.544
MOD_NEK2_1	19	24	PF00069	0.732
MOD_NEK2_1	40	45	PF00069	0.600
MOD_PIKK_1	46	52	PF00454	0.623
MOD_PK_1	82	88	PF00069	0.623
MOD_PKA_2	147	153	PF00069	0.652
MOD_Plk_1	11	17	PF00069	0.537
MOD_Plk_1	235	241	PF00069	0.489
MOD_Plk_1	59	65	PF00069	0.515
MOD_Plk_2-3	147	153	PF00069	0.618
MOD_Plk_2-3	224	230	PF00069	0.335
MOD_Plk_4	11	17	PF00069	0.587
MOD_Plk_4	123	129	PF00069	0.549
MOD_Plk_4	60	66	PF00069	0.585
MOD_ProDKin_1	50	56	PF00069	0.686
MOD_SUMO_rev_2	146	151	PF00179	0.676
MOD_SUMO_rev_2	159	163	PF00179	0.457
MOD_SUMO_rev_2	184	191	PF00179	0.494
TRG_DiLeu_BaLyEn_6	163	168	PF01217	0.463
TRG_ENDOCYTIC_2	173	176	PF00928	0.344
TRG_ENDOCYTIC_2	83	86	PF00928	0.632
TRG_ER_diArg_1	163	166	PF00400	0.471
TRG_ER_diArg_1	232	234	PF00400	0.453
TRG_NLS_MonoExtN_4	190	197	PF00514	0.313

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7W1	Leptomonas seymouri	59%	85%
A0A3Q8IQI1	Leishmania donovani	92%	100%
A4HNS1	Leishmania braziliensis	71%	100%
A4ICS3	Leishmania infantum	92%	100%
E9ASI1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%