Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

KREPA4, putative

Species:

Leishmania major

UniProt:

Q4Q207_LEIMA

TriTrypDb:

LmjF.36.0690 , LMJLV39_360012600 , LMJSD75_360012500

Length:

268

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q207

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q207

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	2	4	PF00675	0.557
CLV_NRD_NRD_1	209	211	PF00675	0.562
CLV_NRD_NRD_1	51	53	PF00675	0.627
CLV_NRD_NRD_1	76	78	PF00675	0.594
CLV_PCSK_KEX2_1	132	134	PF00082	0.671
CLV_PCSK_KEX2_1	2	4	PF00082	0.557
CLV_PCSK_KEX2_1	209	211	PF00082	0.562
CLV_PCSK_KEX2_1	51	53	PF00082	0.683
CLV_PCSK_KEX2_1	75	77	PF00082	0.644
CLV_PCSK_PC1ET2_1	132	134	PF00082	0.773
CLV_PCSK_PC1ET2_1	75	77	PF00082	0.728
CLV_PCSK_SKI1_1	133	137	PF00082	0.537
CLV_PCSK_SKI1_1	163	167	PF00082	0.580
CLV_PCSK_SKI1_1	209	213	PF00082	0.455
CLV_PCSK_SKI1_1	27	31	PF00082	0.702
CLV_PCSK_SKI1_1	62	66	PF00082	0.657
CLV_PCSK_SKI1_1	85	89	PF00082	0.667
DEG_Nend_UBRbox_1	1	4	PF02207	0.759
DEG_SPOP_SBC_1	197	201	PF00917	0.542
DEG_SPOP_SBC_1	64	68	PF00917	0.654
DOC_MAPK_DCC_7	242	251	PF00069	0.520
DOC_MAPK_MEF2A_6	242	251	PF00069	0.520
DOC_PP2B_LxvP_1	261	264	PF13499	0.397
DOC_USP7_MATH_1	122	126	PF00917	0.756
DOC_USP7_MATH_1	17	21	PF00917	0.783
DOC_USP7_MATH_1	180	184	PF00917	0.628
DOC_USP7_MATH_1	196	200	PF00917	0.717
DOC_USP7_MATH_1	42	46	PF00917	0.596
DOC_WW_Pin1_4	153	158	PF00397	0.656
DOC_WW_Pin1_4	164	169	PF00397	0.512
LIG_14-3-3_CanoR_1	133	140	PF00244	0.527
LIG_14-3-3_CanoR_1	209	215	PF00244	0.389
LIG_14-3-3_CanoR_1	62	71	PF00244	0.633
LIG_14-3-3_CanoR_1	85	93	PF00244	0.766
LIG_FHA_1	135	141	PF00498	0.621
LIG_FHA_1	90	96	PF00498	0.649
LIG_FHA_2	199	205	PF00498	0.614
LIG_LIR_Nem_3	68	74	PF02991	0.639
LIG_MYND_3	246	250	PF01753	0.598
LIG_PCNA_yPIPBox_3	222	236	PF02747	0.514
LIG_SH2_SRC	108	111	PF00017	0.563
LIG_SH2_STAT5	108	111	PF00017	0.601
LIG_SH3_3	241	247	PF00018	0.555
LIG_SUMO_SIM_par_1	22	28	PF11976	0.641
LIG_SUMO_SIM_par_1	90	96	PF11976	0.641
LIG_TRAF2_1	70	73	PF00917	0.711
MOD_CK1_1	11	17	PF00069	0.673
MOD_CK1_1	153	159	PF00069	0.667
MOD_CK1_1	183	189	PF00069	0.634
MOD_CK1_1	200	206	PF00069	0.708
MOD_CK1_1	45	51	PF00069	0.651
MOD_CK1_1	66	72	PF00069	0.690
MOD_CK2_1	198	204	PF00069	0.500
MOD_CK2_1	210	216	PF00069	0.331
MOD_CK2_1	22	28	PF00069	0.660
MOD_CK2_1	66	72	PF00069	0.646
MOD_Cter_Amidation	130	133	PF01082	0.696
MOD_GlcNHglycan	10	13	PF01048	0.667
MOD_GlcNHglycan	124	127	PF01048	0.649
MOD_GlcNHglycan	19	22	PF01048	0.728
MOD_GlcNHglycan	226	229	PF01048	0.480
MOD_GlcNHglycan	40	43	PF01048	0.765
MOD_GlcNHglycan	55	58	PF01048	0.630
MOD_GSK3_1	134	141	PF00069	0.616
MOD_GSK3_1	180	187	PF00069	0.767
MOD_GSK3_1	188	195	PF00069	0.666
MOD_GSK3_1	196	203	PF00069	0.673
MOD_GSK3_1	38	45	PF00069	0.662
MOD_GSK3_1	62	69	PF00069	0.675
MOD_GSK3_1	8	15	PF00069	0.686
MOD_GSK3_1	85	92	PF00069	0.646
MOD_N-GLC_1	12	17	PF02516	0.695
MOD_N-GLC_1	141	146	PF02516	0.576
MOD_N-GLC_1	42	47	PF02516	0.602
MOD_N-GLC_1	62	67	PF02516	0.612
MOD_NEK2_1	150	155	PF00069	0.605
MOD_NEK2_1	256	261	PF00069	0.601
MOD_NEK2_1	8	13	PF00069	0.644
MOD_NEK2_2	103	108	PF00069	0.536
MOD_NEK2_2	22	27	PF00069	0.687
MOD_PKA_1	51	57	PF00069	0.618
MOD_PKA_2	51	57	PF00069	0.676
MOD_Plk_1	27	33	PF00069	0.609
MOD_Plk_1	89	95	PF00069	0.573
MOD_Plk_4	103	109	PF00069	0.529
MOD_Plk_4	256	262	PF00069	0.370
MOD_Plk_4	45	51	PF00069	0.766
MOD_ProDKin_1	153	159	PF00069	0.654
MOD_ProDKin_1	164	170	PF00069	0.508
TRG_ER_diArg_1	1	3	PF00400	0.558
TRG_ER_diArg_1	208	210	PF00400	0.579
TRG_ER_diArg_1	50	52	PF00400	0.681
TRG_NES_CRM1_1	239	250	PF08389	0.542
TRG_Pf-PMV_PEXEL_1	85	90	PF00026	0.671

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFQ8	Leptomonas seymouri	37%	89%
A0A3S7XAG1	Leishmania donovani	90%	100%
A4HNS9	Leishmania braziliensis	76%	100%
A4ICR5	Leishmania infantum	90%	100%
E9ASI9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%