Zinc_finger_protein_family_member_-_putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

zinc finger protein family member, putative

Species:

Leishmania major

UniProt:

Q4Q203_LEIMA

TriTrypDb:

LmjF.36.0730 , LMJLV39_360013000 , LMJSD75_360012900

Length:

554

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q203

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q203

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003723	RNA binding	4	2
GO:0005488	binding	1	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	201	205	PF00656	0.433
CLV_C14_Caspase3-7	421	425	PF00656	0.678
CLV_MEL_PAP_1	478	484	PF00089	0.638
CLV_NRD_NRD_1	539	541	PF00675	0.645
CLV_NRD_NRD_1	75	77	PF00675	0.586
CLV_NRD_NRD_1	81	83	PF00675	0.513
CLV_PCSK_KEX2_1	539	541	PF00082	0.645
CLV_PCSK_KEX2_1	75	77	PF00082	0.586
CLV_PCSK_KEX2_1	81	83	PF00082	0.513
CLV_PCSK_SKI1_1	158	162	PF00082	0.515
DEG_SPOP_SBC_1	548	552	PF00917	0.679
DEG_SPOP_SBC_1	68	72	PF00917	0.597
DOC_CKS1_1	271	276	PF01111	0.474
DOC_CKS1_1	499	504	PF01111	0.671
DOC_MAPK_DCC_7	256	266	PF00069	0.417
DOC_MAPK_DCC_7	299	309	PF00069	0.408
DOC_MAPK_DCC_7	488	498	PF00069	0.659
DOC_MAPK_FxFP_2	161	164	PF00069	0.372
DOC_MAPK_MEF2A_6	20	29	PF00069	0.436
DOC_MAPK_MEF2A_6	328	337	PF00069	0.375
DOC_MAPK_MEF2A_6	492	500	PF00069	0.663
DOC_PP1_RVXF_1	18	24	PF00149	0.434
DOC_PP2B_LxvP_1	5	8	PF13499	0.425
DOC_PP4_FxxP_1	161	164	PF00568	0.372
DOC_PP4_FxxP_1	93	96	PF00568	0.366
DOC_USP7_MATH_1	428	432	PF00917	0.652
DOC_USP7_MATH_1	457	461	PF00917	0.733
DOC_USP7_MATH_1	69	73	PF00917	0.561
DOC_USP7_MATH_2	342	348	PF00917	0.579
DOC_WW_Pin1_4	149	154	PF00397	0.448
DOC_WW_Pin1_4	169	174	PF00397	0.350
DOC_WW_Pin1_4	270	275	PF00397	0.466
DOC_WW_Pin1_4	336	341	PF00397	0.429
DOC_WW_Pin1_4	348	353	PF00397	0.549
DOC_WW_Pin1_4	366	371	PF00397	0.569
DOC_WW_Pin1_4	480	485	PF00397	0.716
DOC_WW_Pin1_4	491	496	PF00397	0.591
DOC_WW_Pin1_4	498	503	PF00397	0.606
DOC_WW_Pin1_4	511	516	PF00397	0.510
DOC_WW_Pin1_4	523	528	PF00397	0.634
DOC_WW_Pin1_4	533	538	PF00397	0.606
DOC_WW_Pin1_4	544	549	PF00397	0.627
DOC_WW_Pin1_4	64	69	PF00397	0.588
DOC_WW_Pin1_4	74	79	PF00397	0.576
LIG_14-3-3_CanoR_1	20	24	PF00244	0.435
LIG_14-3-3_CanoR_1	30	36	PF00244	0.429
LIG_14-3-3_CanoR_1	435	440	PF00244	0.551
LIG_14-3-3_CanoR_1	52	62	PF00244	0.646
LIG_14-3-3_CanoR_1	81	85	PF00244	0.492
LIG_14-3-3_CanoR_1	87	92	PF00244	0.399
LIG_APCC_ABBA_1	151	156	PF00400	0.397
LIG_APCC_ABBA_1	175	180	PF00400	0.342
LIG_APCC_ABBA_1	196	201	PF00400	0.433
LIG_CtBP_PxDLS_1	472	476	PF00389	0.607
LIG_FHA_1	299	305	PF00498	0.590
LIG_FHA_1	315	321	PF00498	0.266
LIG_FHA_1	382	388	PF00498	0.635
LIG_FHA_1	439	445	PF00498	0.630
LIG_FHA_1	533	539	PF00498	0.707
LIG_FHA_2	112	118	PF00498	0.607
LIG_FHA_2	271	277	PF00498	0.506
LIG_FHA_2	290	296	PF00498	0.507
LIG_IBAR_NPY_1	542	544	PF08397	0.627
LIG_Integrin_isoDGR_2	433	435	PF01839	0.678
LIG_Integrin_isoDGR_2	79	81	PF01839	0.545
LIG_LIR_Apic_2	159	164	PF02991	0.390
LIG_LIR_Apic_2	90	96	PF02991	0.370
LIG_LIR_Gen_1	192	199	PF02991	0.424
LIG_LIR_Gen_1	22	31	PF02991	0.440
LIG_LIR_Nem_3	192	198	PF02991	0.520
LIG_LIR_Nem_3	22	27	PF02991	0.434
LIG_LIR_Nem_3	239	244	PF02991	0.393
LIG_MYND_2	261	265	PF01753	0.422
LIG_NRBOX	146	152	PF00104	0.437
LIG_Pex14_2	24	28	PF04695	0.436
LIG_SH2_CRK	179	183	PF00017	0.391
LIG_SH2_CRK	470	474	PF00017	0.572
LIG_SH2_NCK_1	179	183	PF00017	0.343
LIG_SH2_NCK_1	294	298	PF00017	0.389
LIG_SH2_PTP2	139	142	PF00017	0.406
LIG_SH2_PTP2	195	198	PF00017	0.378
LIG_SH2_SRC	139	142	PF00017	0.406
LIG_SH2_SRC	179	182	PF00017	0.345
LIG_SH2_SRC	294	297	PF00017	0.389
LIG_SH2_STAP1	294	298	PF00017	0.429
LIG_SH2_STAT3	439	442	PF00017	0.697
LIG_SH2_STAT3	458	461	PF00017	0.507
LIG_SH2_STAT5	139	142	PF00017	0.417
LIG_SH2_STAT5	146	149	PF00017	0.400
LIG_SH2_STAT5	171	174	PF00017	0.434
LIG_SH2_STAT5	195	198	PF00017	0.469
LIG_SH2_STAT5	418	421	PF00017	0.797
LIG_SH3_3	137	143	PF00018	0.350
LIG_SH3_3	265	271	PF00018	0.436
LIG_SH3_3	466	472	PF00018	0.561
LIG_SH3_3	496	502	PF00018	0.739
LIG_SH3_3	513	519	PF00018	0.534
LIG_SUMO_SIM_par_1	514	520	PF11976	0.626
LIG_TRAF2_1	342	345	PF00917	0.662
LIG_TRAF2_1	83	86	PF00917	0.456
LIG_TRFH_1	544	548	PF08558	0.628
MOD_CDC14_SPxK_1	494	497	PF00782	0.595
MOD_CDC14_SPxK_1	536	539	PF00782	0.640
MOD_CDK_SPxK_1	491	497	PF00069	0.594
MOD_CDK_SPxK_1	533	539	PF00069	0.642
MOD_CDK_SPxxK_3	533	540	PF00069	0.642
MOD_CDK_SPxxK_3	74	81	PF00069	0.568
MOD_CK1_1	19	25	PF00069	0.437
MOD_CK1_1	347	353	PF00069	0.610
MOD_CK1_1	360	366	PF00069	0.527
MOD_CK1_1	46	52	PF00069	0.686
MOD_CK1_1	514	520	PF00069	0.627
MOD_CK1_1	523	529	PF00069	0.635
MOD_CK1_1	533	539	PF00069	0.642
MOD_CK1_1	547	553	PF00069	0.541
MOD_CK1_1	56	62	PF00069	0.615
MOD_CK1_1	64	70	PF00069	0.623
MOD_CK2_1	111	117	PF00069	0.463
MOD_CK2_1	289	295	PF00069	0.450
MOD_CK2_1	338	344	PF00069	0.503
MOD_CK2_1	67	73	PF00069	0.591
MOD_CK2_1	80	86	PF00069	0.493
MOD_CK2_1	94	100	PF00069	0.392
MOD_Cter_Amidation	73	76	PF01082	0.596
MOD_Cter_Amidation	79	82	PF01082	0.543
MOD_GlcNHglycan	132	135	PF01048	0.590
MOD_GlcNHglycan	359	362	PF01048	0.643
MOD_GlcNHglycan	45	48	PF01048	0.736
MOD_GlcNHglycan	489	492	PF01048	0.692
MOD_GlcNHglycan	519	522	PF01048	0.630
MOD_GlcNHglycan	523	526	PF01048	0.634
MOD_GlcNHglycan	58	61	PF01048	0.499
MOD_GSK3_1	243	250	PF00069	0.428
MOD_GSK3_1	285	292	PF00069	0.441
MOD_GSK3_1	31	38	PF00069	0.442
MOD_GSK3_1	344	351	PF00069	0.596
MOD_GSK3_1	353	360	PF00069	0.549
MOD_GSK3_1	366	373	PF00069	0.549
MOD_GSK3_1	379	386	PF00069	0.554
MOD_GSK3_1	487	494	PF00069	0.709
MOD_GSK3_1	517	524	PF00069	0.696
MOD_GSK3_1	52	59	PF00069	0.598
MOD_GSK3_1	542	549	PF00069	0.687
MOD_GSK3_1	64	71	PF00069	0.588
MOD_GSK3_1	94	101	PF00069	0.438
MOD_N-GLC_1	52	57	PF02516	0.647
MOD_N-GLC_2	135	137	PF02516	0.379
MOD_NEK2_1	122	127	PF00069	0.411
MOD_NEK2_1	31	36	PF00069	0.478
MOD_NEK2_1	383	388	PF00069	0.558
MOD_NEK2_1	423	428	PF00069	0.556
MOD_PIKK_1	289	295	PF00454	0.450
MOD_PIKK_1	438	444	PF00454	0.673
MOD_PIKK_1	457	463	PF00454	0.501
MOD_PIKK_1	46	52	PF00454	0.635
MOD_PIKK_1	525	531	PF00454	0.701
MOD_PKA_2	19	25	PF00069	0.435
MOD_PKA_2	247	253	PF00069	0.394
MOD_PKA_2	487	493	PF00069	0.594
MOD_PKA_2	80	86	PF00069	0.493
MOD_Plk_1	344	350	PF00069	0.549
MOD_Plk_1	423	429	PF00069	0.620
MOD_Plk_4	122	128	PF00069	0.419
MOD_Plk_4	156	162	PF00069	0.377
MOD_Plk_4	19	25	PF00069	0.464
MOD_Plk_4	31	37	PF00069	0.535
MOD_Plk_4	463	469	PF00069	0.606
MOD_ProDKin_1	149	155	PF00069	0.444
MOD_ProDKin_1	169	175	PF00069	0.348
MOD_ProDKin_1	270	276	PF00069	0.471
MOD_ProDKin_1	336	342	PF00069	0.436
MOD_ProDKin_1	348	354	PF00069	0.550
MOD_ProDKin_1	366	372	PF00069	0.567
MOD_ProDKin_1	480	486	PF00069	0.716
MOD_ProDKin_1	491	497	PF00069	0.594
MOD_ProDKin_1	498	504	PF00069	0.606
MOD_ProDKin_1	511	517	PF00069	0.510
MOD_ProDKin_1	523	529	PF00069	0.635
MOD_ProDKin_1	533	539	PF00069	0.607
MOD_ProDKin_1	544	550	PF00069	0.626
MOD_ProDKin_1	64	70	PF00069	0.588
MOD_ProDKin_1	74	80	PF00069	0.571
MOD_SUMO_rev_2	152	160	PF00179	0.574
TRG_DiLeu_BaLyEn_6	146	151	PF01217	0.431
TRG_ENDOCYTIC_2	139	142	PF00928	0.406
TRG_ENDOCYTIC_2	163	166	PF00928	0.415
TRG_ENDOCYTIC_2	178	181	PF00928	0.511
TRG_ENDOCYTIC_2	195	198	PF00928	0.426
TRG_ENDOCYTIC_2	257	260	PF00928	0.449
TRG_ENDOCYTIC_2	470	473	PF00928	0.663
TRG_ER_diArg_1	538	540	PF00400	0.646
TRG_Pf-PMV_PEXEL_1	391	395	PF00026	0.597

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P889	Leptomonas seymouri	63%	100%
A0A3S7XAD0	Leishmania donovani	95%	100%
A4HNT3	Leishmania braziliensis	84%	100%
A4ICR1	Leishmania infantum	95%	100%
E9ASJ3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%