Putative DEAH-box RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

pre-mRNA splicing factor ATP-dependent RNA helicase, putative

Species:

Leishmania major

UniProt:

Q4Q1Y9_LEIMA

TriTrypDb:

LmjF.36.0870 , LMJLV39_360014400 , LMJSD75_360014400

Length:

942

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	2
GO:0005681	spliceosomal complex	3	2
GO:0032991	protein-containing complex	1	2
GO:0110165	cellular anatomical entity	1	2
GO:0140513	nuclear protein-containing complex	2	2
GO:1990904	ribonucleoprotein complex	2	2

Expansion

Sequence features

Q4Q1Y9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q1Y9

Function

Biological processes
Term	Name	Level	Count
GO:0000375	RNA splicing, via transesterification reactions	8	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006396	RNA processing	6	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0008380	RNA splicing	7	2
GO:0009987	cellular process	1	2
GO:0016070	RNA metabolic process	5	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0046483	heterocycle metabolic process	3	2
GO:0071704	organic substance metabolic process	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	2
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0016787	hydrolase activity	2	9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	612	616	PF00656	0.369
CLV_C14_Caspase3-7	772	776	PF00656	0.671
CLV_NRD_NRD_1	18	20	PF00675	0.549
CLV_NRD_NRD_1	190	192	PF00675	0.450
CLV_NRD_NRD_1	241	243	PF00675	0.304
CLV_NRD_NRD_1	286	288	PF00675	0.262
CLV_NRD_NRD_1	373	375	PF00675	0.252
CLV_NRD_NRD_1	500	502	PF00675	0.256
CLV_NRD_NRD_1	646	648	PF00675	0.275
CLV_NRD_NRD_1	7	9	PF00675	0.571
CLV_NRD_NRD_1	74	76	PF00675	0.647
CLV_NRD_NRD_1	838	840	PF00675	0.542
CLV_NRD_NRD_1	863	865	PF00675	0.642
CLV_NRD_NRD_1	899	901	PF00675	0.556
CLV_NRD_NRD_1	936	938	PF00675	0.589
CLV_PCSK_KEX2_1	190	192	PF00082	0.479
CLV_PCSK_KEX2_1	243	245	PF00082	0.272
CLV_PCSK_KEX2_1	286	288	PF00082	0.278
CLV_PCSK_KEX2_1	373	375	PF00082	0.252
CLV_PCSK_KEX2_1	646	648	PF00082	0.275
CLV_PCSK_KEX2_1	7	9	PF00082	0.631
CLV_PCSK_KEX2_1	73	75	PF00082	0.628
CLV_PCSK_KEX2_1	838	840	PF00082	0.646
CLV_PCSK_KEX2_1	899	901	PF00082	0.506
CLV_PCSK_KEX2_1	903	905	PF00082	0.384
CLV_PCSK_KEX2_1	938	940	PF00082	0.653
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.272
CLV_PCSK_PC1ET2_1	903	905	PF00082	0.422
CLV_PCSK_PC1ET2_1	938	940	PF00082	0.653
CLV_PCSK_PC7_1	369	375	PF00082	0.336
CLV_PCSK_PC7_1	899	905	PF00082	0.455
CLV_PCSK_SKI1_1	14	18	PF00082	0.555
CLV_PCSK_SKI1_1	156	160	PF00082	0.527
CLV_PCSK_SKI1_1	243	247	PF00082	0.329
CLV_PCSK_SKI1_1	3	7	PF00082	0.642
CLV_PCSK_SKI1_1	324	328	PF00082	0.253
CLV_PCSK_SKI1_1	335	339	PF00082	0.277
CLV_PCSK_SKI1_1	473	477	PF00082	0.262
CLV_PCSK_SKI1_1	569	573	PF00082	0.413
CLV_PCSK_SKI1_1	690	694	PF00082	0.338
CLV_PCSK_SKI1_1	742	746	PF00082	0.396
CLV_PCSK_SKI1_1	748	752	PF00082	0.358
CLV_PCSK_SKI1_1	75	79	PF00082	0.670
CLV_PCSK_SKI1_1	803	807	PF00082	0.369
CLV_PCSK_SKI1_1	904	908	PF00082	0.530
CLV_Separin_Metazoa	587	591	PF03568	0.389
DEG_APCC_DBOX_1	198	206	PF00400	0.319
DEG_APCC_DBOX_1	747	755	PF00400	0.399
DEG_Nend_UBRbox_2	1	3	PF02207	0.609
DEG_SPOP_SBC_1	99	103	PF00917	0.549
DOC_AGCK_PIF_1	571	576	PF00069	0.493
DOC_CKS1_1	246	251	PF01111	0.555
DOC_CYCLIN_RxL_1	240	248	PF00134	0.524
DOC_CYCLIN_RxL_1	318	330	PF00134	0.476
DOC_CYCLIN_RxL_1	800	807	PF00134	0.420
DOC_CYCLIN_yCln2_LP_2	246	252	PF00134	0.545
DOC_MAPK_DCC_7	469	477	PF00069	0.498
DOC_MAPK_gen_1	204	214	PF00069	0.459
DOC_MAPK_gen_1	286	293	PF00069	0.462
DOC_MAPK_gen_1	373	380	PF00069	0.450
DOC_MAPK_gen_1	887	896	PF00069	0.389
DOC_MAPK_HePTP_8	886	898	PF00069	0.472
DOC_MAPK_MEF2A_6	207	215	PF00069	0.441
DOC_MAPK_MEF2A_6	373	382	PF00069	0.450
DOC_MAPK_MEF2A_6	469	478	PF00069	0.462
DOC_MAPK_MEF2A_6	756	765	PF00069	0.549
DOC_MAPK_MEF2A_6	887	896	PF00069	0.396
DOC_PP1_RVXF_1	310	316	PF00149	0.450
DOC_PP1_RVXF_1	322	328	PF00149	0.450
DOC_PP2B_LxvP_1	476	479	PF13499	0.462
DOC_PP2B_LxvP_1	614	617	PF13499	0.425
DOC_USP7_MATH_1	139	143	PF00917	0.612
DOC_USP7_MATH_1	252	256	PF00917	0.540
DOC_USP7_MATH_1	304	308	PF00917	0.562
DOC_USP7_MATH_1	510	514	PF00917	0.450
DOC_USP7_MATH_1	769	773	PF00917	0.650
DOC_USP7_MATH_1	837	841	PF00917	0.698
DOC_USP7_MATH_1	846	850	PF00917	0.534
DOC_USP7_MATH_1	911	915	PF00917	0.442
DOC_USP7_MATH_1	99	103	PF00917	0.746
DOC_WW_Pin1_4	245	250	PF00397	0.526
DOC_WW_Pin1_4	493	498	PF00397	0.452
DOC_WW_Pin1_4	868	873	PF00397	0.732
LIG_14-3-3_CanoR_1	138	148	PF00244	0.734
LIG_14-3-3_CanoR_1	190	194	PF00244	0.403
LIG_14-3-3_CanoR_1	244	249	PF00244	0.553
LIG_14-3-3_CanoR_1	279	285	PF00244	0.475
LIG_14-3-3_CanoR_1	357	367	PF00244	0.457
LIG_14-3-3_CanoR_1	558	564	PF00244	0.462
LIG_14-3-3_CanoR_1	569	576	PF00244	0.399
LIG_14-3-3_CanoR_1	590	600	PF00244	0.345
LIG_14-3-3_CanoR_1	640	644	PF00244	0.462
LIG_14-3-3_CanoR_1	87	95	PF00244	0.720
LIG_14-3-3_CanoR_1	899	906	PF00244	0.469
LIG_Actin_WH2_2	356	371	PF00022	0.450
LIG_Actin_WH2_2	710	727	PF00022	0.414
LIG_AP2alpha_1	392	396	PF02296	0.471
LIG_BIR_III_4	261	265	PF00653	0.389
LIG_BRCT_BRCA1_1	100	104	PF00533	0.521
LIG_BRCT_BRCA1_1	392	396	PF00533	0.385
LIG_BRCT_BRCA1_1	65	69	PF00533	0.675
LIG_BRCT_BRCA1_1	806	810	PF00533	0.390
LIG_BRCT_BRCA1_1	856	860	PF00533	0.423
LIG_BRCT_BRCA1_2	392	398	PF00533	0.517
LIG_Clathr_ClatBox_1	608	612	PF01394	0.380
LIG_FHA_1	101	107	PF00498	0.545
LIG_FHA_1	221	227	PF00498	0.459
LIG_FHA_1	317	323	PF00498	0.469
LIG_FHA_1	359	365	PF00498	0.475
LIG_FHA_1	406	412	PF00498	0.413
LIG_FHA_1	498	504	PF00498	0.459
LIG_FHA_1	617	623	PF00498	0.413
LIG_FHA_1	712	718	PF00498	0.460
LIG_FHA_1	800	806	PF00498	0.336
LIG_FHA_1	854	860	PF00498	0.465
LIG_FHA_1	869	875	PF00498	0.723
LIG_FHA_2	165	171	PF00498	0.525
LIG_FHA_2	196	202	PF00498	0.509
LIG_FHA_2	29	35	PF00498	0.637
LIG_FHA_2	582	588	PF00498	0.391
LIG_FHA_2	62	68	PF00498	0.627
LIG_LIR_Apic_2	531	535	PF02991	0.491
LIG_LIR_Gen_1	142	153	PF02991	0.582
LIG_LIR_Gen_1	165	176	PF02991	0.630
LIG_LIR_Gen_1	390	400	PF02991	0.504
LIG_LIR_Gen_1	714	724	PF02991	0.472
LIG_LIR_Gen_1	757	765	PF02991	0.513
LIG_LIR_Gen_1	819	829	PF02991	0.439
LIG_LIR_Gen_1	86	96	PF02991	0.703
LIG_LIR_LC3C_4	822	826	PF02991	0.440
LIG_LIR_Nem_3	165	171	PF02991	0.633
LIG_LIR_Nem_3	390	395	PF02991	0.502
LIG_LIR_Nem_3	566	571	PF02991	0.403
LIG_LIR_Nem_3	714	719	PF02991	0.405
LIG_LIR_Nem_3	757	761	PF02991	0.493
LIG_LIR_Nem_3	807	813	PF02991	0.342
LIG_LIR_Nem_3	819	824	PF02991	0.363
LIG_LIR_Nem_3	86	91	PF02991	0.737
LIG_MLH1_MIPbox_1	392	396	PF16413	0.385
LIG_MLH1_MIPbox_1	806	810	PF16413	0.390
LIG_NRBOX	363	369	PF00104	0.450
LIG_PCNA_yPIPBox_3	710	718	PF02747	0.362
LIG_Pex14_2	392	396	PF04695	0.351
LIG_REV1ctd_RIR_1	393	399	PF16727	0.491
LIG_SH2_CRK	481	485	PF00017	0.374
LIG_SH2_GRB2like	532	535	PF00017	0.491
LIG_SH2_PTP2	716	719	PF00017	0.347
LIG_SH2_SRC	231	234	PF00017	0.511
LIG_SH2_STAT3	533	536	PF00017	0.511
LIG_SH2_STAT5	145	148	PF00017	0.612
LIG_SH2_STAT5	162	165	PF00017	0.464
LIG_SH2_STAT5	229	232	PF00017	0.469
LIG_SH2_STAT5	423	426	PF00017	0.382
LIG_SH2_STAT5	521	524	PF00017	0.450
LIG_SH2_STAT5	574	577	PF00017	0.432
LIG_SH2_STAT5	716	719	PF00017	0.347
LIG_SH2_STAT5	823	826	PF00017	0.362
LIG_SH2_STAT5	926	929	PF00017	0.440
LIG_SH3_3	121	127	PF00018	0.655
LIG_SH3_3	298	304	PF00018	0.536
LIG_SH3_3	443	449	PF00018	0.475
LIG_SH3_3	649	655	PF00018	0.442
LIG_SH3_3	822	828	PF00018	0.473
LIG_SH3_3	93	99	PF00018	0.712
LIG_SH3_5	419	423	PF00018	0.410
LIG_Sin3_3	128	135	PF02671	0.506
LIG_SUMO_SIM_par_1	211	218	PF11976	0.442
LIG_SUMO_SIM_par_1	678	684	PF11976	0.475
LIG_TRAF2_1	198	201	PF00917	0.488
LIG_TRFH_1	235	239	PF08558	0.536
LIG_TRFH_1	651	655	PF08558	0.511
LIG_UBA3_1	629	636	PF00899	0.454
LIG_WRC_WIRS_1	755	760	PF05994	0.470
MOD_CK1_1	220	226	PF00069	0.450
MOD_CK1_1	358	364	PF00069	0.459
MOD_CK1_1	405	411	PF00069	0.524
MOD_CK1_1	427	433	PF00069	0.444
MOD_CK1_1	548	554	PF00069	0.448
MOD_CK1_1	618	624	PF00069	0.419
MOD_CK1_1	770	776	PF00069	0.574
MOD_CK1_1	832	838	PF00069	0.746
MOD_CK1_1	873	879	PF00069	0.659
MOD_CK2_1	146	152	PF00069	0.570
MOD_CK2_1	164	170	PF00069	0.433
MOD_CK2_1	195	201	PF00069	0.331
MOD_CK2_1	28	34	PF00069	0.598
MOD_CK2_1	289	295	PF00069	0.450
MOD_CK2_1	45	51	PF00069	0.349
MOD_CK2_1	581	587	PF00069	0.398
MOD_CK2_1	61	67	PF00069	0.512
MOD_CK2_1	697	703	PF00069	0.577
MOD_CK2_1	846	852	PF00069	0.514
MOD_Cter_Amidation	644	647	PF01082	0.275
MOD_Cter_Amidation	862	865	PF01082	0.619
MOD_GlcNHglycan	124	127	PF01048	0.712
MOD_GlcNHglycan	128	131	PF01048	0.704
MOD_GlcNHglycan	141	144	PF01048	0.641
MOD_GlcNHglycan	219	222	PF01048	0.241
MOD_GlcNHglycan	383	386	PF01048	0.250
MOD_GlcNHglycan	404	407	PF01048	0.567
MOD_GlcNHglycan	426	429	PF01048	0.423
MOD_GlcNHglycan	550	553	PF01048	0.250
MOD_GlcNHglycan	58	61	PF01048	0.588
MOD_GlcNHglycan	593	596	PF01048	0.458
MOD_GlcNHglycan	699	702	PF01048	0.443
MOD_GlcNHglycan	789	792	PF01048	0.628
MOD_GlcNHglycan	806	809	PF01048	0.238
MOD_GlcNHglycan	841	844	PF01048	0.668
MOD_GlcNHglycan	913	916	PF01048	0.477
MOD_GlcNHglycan	920	923	PF01048	0.439
MOD_GSK3_1	122	129	PF00069	0.709
MOD_GSK3_1	134	141	PF00069	0.681
MOD_GSK3_1	217	224	PF00069	0.450
MOD_GSK3_1	316	323	PF00069	0.462
MOD_GSK3_1	493	500	PF00069	0.521
MOD_GSK3_1	544	551	PF00069	0.487
MOD_GSK3_1	767	774	PF00069	0.653
MOD_GSK3_1	828	835	PF00069	0.655
MOD_GSK3_1	868	875	PF00069	0.606
MOD_GSK3_1	907	914	PF00069	0.395
MOD_GSK3_1	94	101	PF00069	0.727
MOD_LATS_1	355	361	PF00433	0.555
MOD_NEK2_1	133	138	PF00069	0.652
MOD_NEK2_1	280	285	PF00069	0.447
MOD_NEK2_1	402	407	PF00069	0.473
MOD_NEK2_1	434	439	PF00069	0.396
MOD_NEK2_1	589	594	PF00069	0.392
MOD_NEK2_1	641	646	PF00069	0.450
MOD_NEK2_1	829	834	PF00069	0.618
MOD_NEK2_1	898	903	PF00069	0.471
MOD_PIKK_1	106	112	PF00454	0.509
MOD_PIKK_1	221	227	PF00454	0.450
MOD_PIKK_1	280	286	PF00454	0.464
MOD_PIKK_1	545	551	PF00454	0.471
MOD_PIKK_1	559	565	PF00454	0.378
MOD_PK_1	870	876	PF00069	0.595
MOD_PKA_1	373	379	PF00069	0.389
MOD_PKA_1	899	905	PF00069	0.539
MOD_PKA_2	189	195	PF00069	0.401
MOD_PKA_2	373	379	PF00069	0.500
MOD_PKA_2	589	595	PF00069	0.374
MOD_PKA_2	639	645	PF00069	0.462
MOD_PKA_2	837	843	PF00069	0.505
MOD_PKA_2	86	92	PF00069	0.716
MOD_PKA_2	863	869	PF00069	0.667
MOD_PKA_2	898	904	PF00069	0.437
MOD_PKB_1	242	250	PF00069	0.500
MOD_Plk_1	106	112	PF00069	0.565
MOD_Plk_1	164	170	PF00069	0.604
MOD_Plk_1	341	347	PF00069	0.501
MOD_Plk_1	355	361	PF00069	0.387
MOD_Plk_1	510	516	PF00069	0.419
MOD_Plk_1	829	835	PF00069	0.570
MOD_Plk_1	846	852	PF00069	0.545
MOD_Plk_4	28	34	PF00069	0.626
MOD_Plk_4	304	310	PF00069	0.491
MOD_Plk_4	427	433	PF00069	0.459
MOD_Plk_4	460	466	PF00069	0.555
MOD_Plk_4	681	687	PF00069	0.451
MOD_Plk_4	854	860	PF00069	0.392
MOD_ProDKin_1	245	251	PF00069	0.526
MOD_ProDKin_1	493	499	PF00069	0.452
MOD_ProDKin_1	868	874	PF00069	0.732
MOD_SUMO_for_1	814	817	PF00179	0.511
MOD_SUMO_rev_2	770	779	PF00179	0.709
TRG_AP2beta_CARGO_1	165	175	PF09066	0.637
TRG_DiLeu_BaEn_1	201	206	PF01217	0.498
TRG_DiLeu_BaEn_1	51	56	PF01217	0.606
TRG_DiLeu_BaEn_1	888	893	PF01217	0.380
TRG_DiLeu_BaEn_4	232	238	PF01217	0.536
TRG_DiLeu_BaEn_4	273	279	PF01217	0.446
TRG_DiLeu_BaLyEn_6	241	246	PF01217	0.500
TRG_DiLeu_BaLyEn_6	276	281	PF01217	0.425
TRG_DiLeu_BaLyEn_6	471	476	PF01217	0.491
TRG_ENDOCYTIC_2	145	148	PF00928	0.619
TRG_ENDOCYTIC_2	481	484	PF00928	0.441
TRG_ENDOCYTIC_2	568	571	PF00928	0.438
TRG_ENDOCYTIC_2	716	719	PF00928	0.347
TRG_ENDOCYTIC_2	823	826	PF00928	0.396
TRG_ER_diArg_1	239	242	PF00400	0.460
TRG_ER_diArg_1	285	287	PF00400	0.462
TRG_ER_diArg_1	372	374	PF00400	0.464
TRG_ER_diArg_1	6	8	PF00400	0.647
TRG_ER_diArg_1	646	648	PF00400	0.475
TRG_ER_diArg_1	73	75	PF00400	0.647
TRG_ER_diArg_1	745	748	PF00400	0.394
TRG_ER_diArg_1	898	900	PF00400	0.558
TRG_ER_diArg_1	936	939	PF00400	0.625
TRG_NES_CRM1_1	587	599	PF08389	0.370
TRG_NLS_MonoExtC_3	936	941	PF00514	0.636
TRG_NLS_MonoExtN_4	239	246	PF00514	0.522
TRG_NLS_MonoExtN_4	937	942	PF00514	0.684
TRG_Pf-PMV_PEXEL_1	268	272	PF00026	0.189
TRG_Pf-PMV_PEXEL_1	357	362	PF00026	0.262
TRG_Pf-PMV_PEXEL_1	38	42	PF00026	0.655
TRG_Pf-PMV_PEXEL_1	777	781	PF00026	0.486

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5V0	Leptomonas seymouri	36%	100%
A0A0N0P8Y1	Leptomonas seymouri	36%	100%
A0A0N0P9D2	Leptomonas seymouri	36%	100%
A0A0N1I0Z0	Leptomonas seymouri	35%	87%
A0A0N1PEU4	Leptomonas seymouri	74%	99%
A0A0S4IQ76	Bodo saltans	34%	100%
A0A0S4IR78	Bodo saltans	49%	100%
A0A0S4IS51	Bodo saltans	35%	100%
A0A0S4ITR4	Bodo saltans	36%	88%
A0A0S4IWU8	Bodo saltans	50%	100%
A0A0S4J157	Bodo saltans	37%	100%
A0A0S4JCY8	Bodo saltans	36%	92%
A0A1X0NJ46	Trypanosomatidae	36%	100%
A0A1X0NKY7	Trypanosomatidae	35%	88%
A0A1X0NUZ7	Trypanosomatidae	31%	72%
A0A1X0NVG5	Trypanosomatidae	38%	88%
A0A1X0P0D7	Trypanosomatidae	36%	100%
A0A1X0P872	Trypanosomatidae	60%	100%
A0A1X0P9K6	Trypanosomatidae	36%	100%
A0A3Q8II71	Leishmania donovani	36%	100%
A0A3Q8IJ24	Leishmania donovani	95%	100%
A0A3Q8IWG4	Leishmania donovani	35%	100%
A0A3R7MA90	Trypanosoma rangeli	36%	100%
A0A3R7MLF0	Trypanosoma rangeli	29%	67%
A0A3R7NT42	Trypanosoma rangeli	36%	100%
A0A3S7WYA1	Leishmania donovani	34%	87%
A0A3S7X8Z5	Leishmania donovani	36%	100%
A0A3S7XB01	Leishmania donovani	35%	87%
A0A422MXB1	Trypanosoma rangeli	37%	89%
A0A422N8L3	Trypanosoma rangeli	34%	93%
A1Z9L3	Drosophila melanogaster	39%	76%
A2A4P0	Mus musculus	39%	76%
A4HAT8	Leishmania braziliensis	36%	100%
A4HME2	Leishmania braziliensis	37%	100%
A4HNU7	Leishmania braziliensis	85%	100%
A4HPE9	Leishmania braziliensis	34%	87%
A4HQ83	Leishmania braziliensis	35%	100%
A4I0U7	Leishmania infantum	34%	87%
A4IA06	Leishmania infantum	36%	100%
A4IB14	Leishmania infantum	36%	100%
A4ICJ0	Leishmania infantum	35%	87%
A4ICP7	Leishmania infantum	95%	100%
A4IDY1	Leishmania infantum	35%	100%
B0XDC4	Culex quinquefasciatus	29%	67%
B8A4F4	Danio rerio	30%	70%
C9ZMN0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
C9ZNP6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
D0A2R5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	58%	100%
D0A3F8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	89%
D0A429	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
D0A778	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	90%
E9AEU3	Leishmania major	36%	93%
E9ASK7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
E9AT60	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	87%
E9AU01	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9B512	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9B5Z9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
F4IE66	Arabidopsis thaliana	34%	100%
F4IJV4	Arabidopsis thaliana	41%	90%
F4JMJ3	Arabidopsis thaliana	37%	100%
F4JRJ6	Arabidopsis thaliana	36%	100%
F4K2E9	Arabidopsis thaliana	34%	75%
O22899	Arabidopsis thaliana	36%	100%
O35286	Mus musculus	36%	100%
O42643	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	81%
O42945	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	100%
O43143	Homo sapiens	36%	100%
O45244	Caenorhabditis elegans	39%	93%
O60231	Homo sapiens	41%	90%
O70133	Mus musculus	28%	68%
P15938	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	88%
P20095	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	100%
P24384	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	82%
P34498	Caenorhabditis elegans	37%	83%
P36009	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	100%
P43329	Escherichia coli (strain K12)	32%	72%
P45018	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	32%	72%
P53131	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	100%
Q03319	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	100%
Q09530	Caenorhabditis elegans	39%	78%
Q10752	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	89%
Q14562	Homo sapiens	39%	77%
Q14BI7	Mus musculus	28%	68%
Q17R09	Bos taurus	36%	77%
Q20875	Caenorhabditis elegans	35%	100%
Q2NKY8	Bos taurus	31%	77%
Q38953	Arabidopsis thaliana	39%	81%
Q3ZBE0	Bos taurus	30%	100%
Q4Q0J4	Leishmania major	35%	91%
Q4Q1D7	Leishmania major	35%	100%
Q4Q2X4	Leishmania major	36%	100%
Q54F05	Dictyostelium discoideum	38%	81%
Q54MH3	Dictyostelium discoideum	40%	85%
Q54NJ4	Dictyostelium discoideum	39%	100%
Q5BJS0	Rattus norvegicus	32%	79%
Q5R607	Pongo abelii	32%	79%
Q5R864	Pongo abelii	36%	100%
Q5RAZ4	Pongo abelii	36%	100%
Q5RBD4	Pongo abelii	37%	100%
Q5XH12	Xenopus laevis	27%	100%
Q5XI69	Rattus norvegicus	35%	100%
Q68FK8	Xenopus laevis	30%	75%
Q6PE54	Mus musculus	36%	100%
Q767K6	Sus scrofa	41%	90%
Q7K3M5	Drosophila melanogaster	36%	100%
Q7L2E3	Homo sapiens	32%	79%
Q7L7V1	Homo sapiens	25%	100%
Q7YR39	Pan troglodytes	41%	90%
Q80VY9	Mus musculus	34%	100%
Q8BZS9	Mus musculus	26%	100%
Q8IX18	Homo sapiens	36%	100%
Q8TE96	Homo sapiens	29%	100%
Q8VY00	Arabidopsis thaliana	40%	90%
Q924H9	Mus musculus	29%	100%
Q92620	Homo sapiens	36%	77%
Q99PU8	Mus musculus	32%	77%
Q9BKQ8	Caenorhabditis elegans	38%	100%
Q9C6G0	Arabidopsis thaliana	31%	66%
Q9H5Z1	Homo sapiens	37%	100%
Q9H6R0	Homo sapiens	34%	100%
Q9HDY4	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	80%
Q9HE06	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
Q9LZQ9	Arabidopsis thaliana	40%	100%
V5B3L7	Trypanosoma cruzi	35%	100%
V5B7H6	Trypanosoma cruzi	32%	86%
V5BKH2	Trypanosoma cruzi	38%	100%
V5BND8	Trypanosoma cruzi	29%	67%
V5BPV3	Trypanosoma cruzi	37%	89%
V5BV22	Trypanosoma cruzi	57%	100%
V5C0I9	Trypanosoma cruzi	35%	100%
V5D886	Trypanosoma cruzi	36%	100%